• Title/Summary/Keyword: Large breast

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Prevalence of Known Risk Factors in Women Diagnosed with Breast Cancer at Inmol Hospital, Lahore, Punjab

  • Mansha, Muhammad;Saleem, Maryam;Wasim, Muhammad;Tariq, Muhammad
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.2
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    • pp.563-568
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    • 2016
  • Background: Breast cancer is the most prevalent cancer in women worldwide and its frequency is increasing gradually in many countries. Over the last three decades an increase in the breast cancer has been witnessed in the earlier low-risk Asian countries including Pakistan. Purpose: The objective of the current study was to assess the prevalence of known risk factors like early menarche, late menopause, socio economic, reproductive and demographic factors, among women diagnosed with breast cancer at INMOL hospital, Lahore, Punjab, as little information exists in this regard. Materials and Methods: A survey study was conducted on 200 women diagnosed with breast cancer who were seen at Institute of Nuclear Medicine and Oncology (INMOL) hospital, Lahore. A structured questionnaire was administered to these patients regarding the known risk factors through face to face interviews after obtaining appropriate consent. Results: Regarding non-modifiable risk factors, our study showed that majority of the breast cancer patients were diagnosed at 35-45 years (32.5%) or at older age (${\leq}46$) and experienced menarche at 12 years or older (66 %). Likewise, a large number of patients reached menopause at the age of 45 years (60%), had no family and personal history of breast cancer (80%) and hence fell in a low risk category. Regarding modifiable risk factors in women diagnosed with breast cancer, most of the patients fell in low risk strata as the majority were married (98%) at young age, breastfed their children for 12 months or more (88%) and bore two to three children (80%). Considering income criteria, the majority of the patients had a low risk profile as they belonged to middle class (70%), urban area (60%) and were house wives (80%). However, it was noted that a considerable number of women (34%) diagnosed with breast cancer experienced menarche at an early age (<12) and reached menopause after the age of 45 years. This situation is further augmented by environmental changes and dietary habits and places them in a high risk category.

Selemium Intake in Breast-fed Infants during Course of Lactation

  • Kim, Eul-Sang;Keum, Hae-Kyoung;Yuzo Tamari
    • Preventive Nutrition and Food Science
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    • v.1 no.2
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    • pp.230-233
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    • 1996
  • The purposes of this study was to investigate selenium content of human milk and selenium intake of breast-fed infants at each period of lactation longitudinally. The human milk intake in breast-fed infants was measured by test weighing method from 20 lactating mothers at 1,2 and 3 months postpartum. Selenium content in the milks was determined by atomic absorption spectrophotometry with hydride generation after wet digestion of samples. Selenium intake in breast-fed infants was calculated by multiplying human milk intakes by selenium contents. The milk intakes were 640, 726 and 715g/day at 1,2 and 3 months postpartum. The selenium contents in human milk were characterized by a pattern of slight decline with advancing stage of lactation;13.1, 11.5 and 9.8$\mu\textrm{g}$/L at 1,2 and 3 months during lactation. There was a large individual variation at any stage of this study. The mean dietary selenium intakes in breast-fed infants were 8.38, 8.32 and 6.97$\mu\textrm{g}$/day at 1,2 and 3 months postpartum, respectively. The mean daily intakes on a body weight basis were gradually decreased during the course of lactation.

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Absence of P53 Gene Mutations in Exons 5 - 7 Among Breast Cancer Patients of Bengalee Hindu Caste Females, West Bengal, India

  • Roy, Abhishikta Ghosh;Sarkar, B.N.;Roy, Rakesh;Rao, V.R.;Bandyopadhyay, A.R.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.9
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    • pp.4477-4479
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    • 2012
  • Background: The high incidence and relatively good prognosis of breast cancer has made it the most prevalent cancer in the world today. A large number of distinct mutations and polymorphisms in the p53 gene have been reported worldwide, but there is no report regarding the role of this inherited susceptibility gene in breast cancer risk among the Bengalee Hindu Caste females of West Bengal, India. Aim of the Study: We investigated the distribution and the nature of p53 gene mutations and polymorphisms in exons 5-7 in a cohort of 110 Bengalee Hindu breast cancer patients and 127 age, sex and caste matched controls by direct sequencing. Results: We did not observe any mutations and polymorphisms in our studied individuals. Conclusion: We therefore conclude that mutations in exons 5-7 of p53 gene are rare causes of breast cancer among Bengalee Hindu caste females, and therefore of little help for genetic counseling and diagnostic purposes.

Fine Needle Aspiration Cytology of Primay Malignant Lymphoma of the Breast - A Case Report - (유방에 발견한 원발신 악성 림프종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Kim, Hyun-Joong;Lee, Kyung-Hwa;Kim, Jo-Heon;Shim, Min-Keun;Choi, Chan;Lee, Ji-Shin
    • The Korean Journal of Cytopathology
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    • v.15 no.2
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    • pp.112-115
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    • 2004
  • Lymphoproliferative disorders, manifesting either as a primary lesion or as part of a generalized process, rarely involve the breast. The primary malignant lymphoma of the breast is rare. The cytologic features of this neoplasm have not been reported in Korea thus far. We described a case of primary malignant lymphoma of the breast, as diagnosed by fine needle aspiration cytology (FNAC) in an 84-year-old female. FNAC smears showed high cellularity. The main cytologic feature observed was a carpeting of monotonous, atypical, enlarged lymphoid cells. These lymphocytes showed relatively round elliptical nuclei with some indentation. One or more prominent nucleoli were seen. Biopy from the breast mass revealed diagnostic features of non-Hodgkin's lymphoma, diffuse large B-cell type.

Effect of Intervention Programs for Improving Maternal Adaptation in Korea: Systematic Review (유방암 생존자 부부를 위한 중재 연구 문헌고찰)

  • Kang, Hee Sun;Yeom, Soo Young;Jun, Eun-Young
    • Women's Health Nursing
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    • v.19 no.3
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    • pp.153-165
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    • 2013
  • Purpose: The purpose of this study was to review the literature on intervention for breast cancer survivors and their partners. Methods: The literature search was performed using MEDLINE, Pubmed, and Proquest to summarize the current state of knowledge regarding intervention for breast cancer survivors and their partners. Articles published between January 2000 and December 2011 were included. Results: A total of 14 studies were identified. Couple-base d intervention was more effective than intervention for survivors alone. Intervention to partners had also effects on their wives. Most studies were conducted in USA with Caucasian women. Sample size of intervention studies was small with most being pilot studies. Conclusion: Providing couple-based intervention to breast cancer survivors could have positive impacts on physical, interpersonal, and social aspects in breast cancer survivors. Future studies with large sample and different ethnicity are needed to confirm the effects of couple-based interventions for breast cancer survivors.

Thermal Infrared Image Analysis for Breast Cancer Detection

  • Min, Sedong;Heo, Jiyoung;Kong, Youngsun;Nam, Yunyoung;Ley, Preap;Jung, Bong-Keun;Oh, Dongik;Shin, Wonhan
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.2
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    • pp.1134-1147
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    • 2017
  • With the rise in popularity of photographic and video cameras, an increasing number of fields are now using thermal imaging cameras. One such application is in the diagnosis of breast cancer, as thermal imaging provides a low-cost and noninvasive method. Thermal imaging is particularly safe for pregnant women, and those with large, dense, or sensitive breasts. In addition, excessive doses of radiation, which may be used in traditional methods of breast cancer detection, can increase the risk of cancer. This paper presents one method of breast cancer detection. Breast images were taken using a thermal camera, with preliminary experiments conducted on Cambodian women. Then the experimental results were analyzed and compared using Shannon entropy and logistic regression.

Unusual US Findings of Diffuse Large B-Cell Lymphoma of the Breast: A Case Report (유방의 B세포 림프종의 비전형적 초음파 영상 소견: 증례 보고)

  • Kyung Eun Lee;Ok Hee Woo;Chung Yeul Kim;Kyu Ran Cho;Bo Kyoung Seo
    • Journal of the Korean Society of Radiology
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    • v.85 no.2
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    • pp.415-420
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    • 2024
  • Lymphoma is an uncommon type of breast malignancy, with low prevalence. The ultrasonographic findings of breast lymphoma have been described as nonspecific. Breast lymphoma most commonly appears as a solitary hypoechoic mass on US, and usually shows hypervascularity on color Doppler US. Herein, we report an unusual case of breast lymphoma that presented as multiple bilateral hyperechoic nodules on US.

Current Progress in the Treatment of Metaplastic Breast Carcinoma

  • Hu, Qing;Chen, Wei-Xian;Zhong, Shan-Liang;Li, Jian;Luo, Zhou;Tang, Jin-Hai;Zhao, Jian-Hua
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6221-6225
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    • 2013
  • Metaplastic breast cancer (MBC) is a rare type of breast carcinoma, characterized by various combinations of mesenchymal, adenocarcinoma and other epithelial components. MBC often manifests as a large mass, with low axillary lymph node involvement and poor prognosis. Knowledge and treatment patterns about MBC demographics, presentation and tumor characteristics are very limited. In clinical practice, MBC is usually treated based on the guidelines developed for infiltrating ductal carcinoma (IDC). The ideal treatment paradigm for MBC is unknown due to its low incidence and pathological variability, so potential predictors of treatment efficacy need to be explored. This review summarizes the current models and strategies for MBC according to the published literature.

Malignant Phyolldes Tumor of the Breast Metastatic to the Lung - A Case Report of Fine Needle Aspiration Cytologic Features - (폐로 전이한 유방의 악성 엽상종양 - 세침흡인 세포학적 소견의 1례 보고 -)

  • Yim, Hyun-Ee;Lee, Kwang-Gil
    • The Korean Journal of Cytopathology
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    • v.4 no.2
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    • pp.160-165
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    • 1993
  • Phyllodes tumor of the breast, especially malignant, is a rare tumor which has characteristic cytologic features. We recently experienced a case of fine needle aspiration cytology of malignant phyllodes tumor of the breast metastatic to the lung. The aspirate showed cellular smear with biphasic population of epithelial and stromal cells. Many individual large cells with round hyperchromatic nuclei were found in the necrotic background and stromal cell atypia was also present. Chondrosarcomatous fragments were also seen in cytologic specimens.

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Fine Needle Aspiration Cytology of Atypical Proliferative Lesion of the Breast (유방의 비정형 증식성 병변의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Song, Kun-Chang;Lee, Kwang-Gil
    • The Korean Journal of Cytopathology
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    • v.5 no.1
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    • pp.52-56
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    • 1994
  • We experienced a case of fine-needle aspiration (FNA) cytology of breast which showed atypical proliferative lesion. It was very difficult to differentiate this case from malignancy, because of hypercellular smear and many clusters composed of large, atypical ductal cells. However, it showed other features favoring benignancy, such as tendency of cellular cohesiveness, only slightly increased nucleus/cytoplasm ratio and most importantly presence of myoepithelial cells. It's histologic diagnosis was intraductal hyperplasia with atypia. This case indicates that all atypical breast FNA specimen should lead to the suggestion of surgical biopsy for avoiding over- or under-diagnosis.

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