• Title/Summary/Keyword: Large breast

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Carbon Emission Study of Transplanting Large Trees from Gangwon Province to Seoul (강원지역 대형 조경수 서울 이식에 따른 탄소 배출 연구)

  • Choi, Yoo;Ahn, Tong-Mahn;Lee, Jae-Won
    • Journal of the Korean Institute of Landscape Architecture
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    • v.41 no.4
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    • pp.10-16
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    • 2013
  • Korean housing developers are in a very competitive market and their way of attracting buyers is landscaping better than competing firms do. Thus, transplanting larger pine trees(Pinus densiflora S. et. Z.) is in vogue. A typical case is a pine tree about 30-year old, 35 diameters at breast height, transplanted 223 km afar from the Gangwon Province to Seoul. We estimated and compared carbon emissions during the whole transplanting works, and carbon intake by the tree if it survives 50 more years on site. Findings are; first, a large tree will take up and sequestrate approximately 90 kgC if it survives 50 more years. Second, transplanting works emit approximately 113.69 kgC, which is about 1.26 times of its possible future intake of carbon. Landscaping is a legal requirement for the purposes not only of aesthetics but also of environmental quality. Transplanting larger trees that came from a dam or a road building site may be inevitable and acceptable. However, transplanting larger trees long distance was evaluated to be harmful to the environment. It is strongly recommended to prohibit transplanting large trees. Landscape professionals need to guide clients to have desirable consumer attitude.

Preoperative Prediction of Ductal Carcinoma in situ Underestimation of the Breast using Dynamic Contrast Enhanced and Diffusion-weighted Imaging (역동적 유방 자기공명 영상 및 확산 강조영상을 이용한 관상피내암종 저평가 수술전 예측)

  • Park, Mina;Kim, Eun-Kyung;Kim, Min Jung;Moon, Hee Jung
    • Investigative Magnetic Resonance Imaging
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    • v.17 no.2
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    • pp.101-109
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    • 2013
  • Objective: To investigate roles of dynamic contrast enhanced magnetic resonance (DCE MR) and diffusion-weighted (DW) imaging in preoperative prediction of underestimation of ductal carcinoma in situ (DCIS) ${\geq}2cm$ on US guided core needle biopsy. Materials and Methods: Twenty two patients with DCIS on US-guided 14 gauge core needle biopsy were included. Patients were divided into a group with and without DCIS underestimation based on histopathology. MR images including DCE and DW imaging were obtained with a 3.0-T MR. The lesion type (mass or non-mass), enhancement pattern, peak enhancement, and apparent diffusion coefficient (ADC) values of proven malignant masses were generated using software of CADstream and compared between two groups using Fisher's exact test and Mann Whitney test. Results: Eight patients were in the group with underestimation and 14 patients were in the group without underestimation. The lesion type and enhancement pattern were not different between two groups (P values = 1.000 and 0.613, respectively). The median peak enhancement of lesions with underestimation was 159.5%, higher than 133.5% of those without underestimation, but not significant (P value = 0.413). The median ADC value of lesions with underestimation was $1.26{\times}10^{-3}mm^2/sec$, substantially lower than $1.35{\times}10^{-3}mm^2/sec$ of those without underestimation (P value = 0.094). Conclusion: ADC values had the potential to preoperatively predict DCIS underestimation on US-guided core needle biopsy, although a large prospective series study should be conducted to confirm these results.

Plasma Transforming Growth Factor-$\beta$1 Levels of Cancer Patients (암 환자의 혈장 Transforming Growth Factor-$\beta$1 농도)

  • 전지현;이시은;이수진;박찬후;장정순;하우송;박순태;박병규
    • Biomedical Science Letters
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    • v.5 no.2
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    • pp.181-190
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    • 1999
  • To evaluate the usefulness of transforming growth factor-$\beta$1 (TGF-$\beta$1) as a new tumor marker, we determined the plasma TGF-$\beta$1 levels using sandwich ELISA assay in cancer patients. Patients with three most common adult cancers in Korea (stomach, liver and breast cancer) and children's cancers (leukemia and two kinds of solid tumor) were enrolled for the study. Furthermore, 39 individuals were subjected to age and sex-stratified plasma TGF-$\beta$1 analysis. No statistical difference was demonstrated with respect to age or sex. The mean plasma TGF-$\beta$1 level (16.0 ng/ ml) of stomach cancer patients was significantly higher than that (8.3 ng/ml) of controls. However, there was no difference among the mean plasma TGF-$\beta$1 levels of liver, breast cancer patients and controls. Seven of 16 patients (43.7%) with stomach cancer, one of 8 (12.5%) with liver cancer, and one of 7 (14.3%) with breast cancer showed higher TGF-$\beta$1 levels compared to controls. Plasma TGF-$\beta$1 concentrations of five leukemic children remained in the normal range regardless of the remission state. In contrast, initial high TGF-$\beta$1 levels from two children with solid tumors returned to normal range on surgical resection of tumors. From the above results, we could conclude that plasma TGF-$\beta$1 levels of apparently healthy individuals seem to be rather constant irrespective of difference in age or sex, and the plasma TGF-$\beta$1 has the limited value as a screening test for the diagnosis of aforementioned adult cancers because of its low sensitivity. Finally, additional studies need to be pursed for the large number of stomach cancer and pediatric solid tumor patients in order to reach a secure conclusion on the usefulness of plasma TGF-$\beta$1 as a tumor marker in these patients.

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Evaluation of the usefulness of IGRT(Image Guided Radiation Therapy) for markerless patients using SGPS(Surface-Guided Patient Setup) (표면유도환자셋업(Surface-Guided Patient Setup, SGPS)을 활용한 Markerless환자의 영상유도방사선치료(Image Guided Radiation Therapy, IGRT)시 유용성 평가)

  • Lee, Kyeong-jae;Lee, Eung-man;Lee, Jeong-su;Kim, Da-yeon;Ko, Hyeon-jun;Choi, Shin-cheol
    • The Journal of Korean Society for Radiation Therapy
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    • v.33
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    • pp.109-116
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    • 2021
  • Purpose: The purpose of this study is to evaluate the usefulness of Surface-Guided Patient Setup by comparing the patient positioning accuracy when image-guided radiation therapy was used for Markerless patients(unmarked on the skin) using Surface-Guided Patient Setup and Marker patients(marked on the skin) using Laser-Based Patient Setup. Materials And Methods: The position error during IGRT was compared between a Markerless patient initially set up with SGPS using an optical surface scanning system using three cameras and a Marker patient initially set up with LBPS that aligns the laser with the marker drawn on the patient's skin. Both SGPS and LBPS were performed on 20 prostate cancer patients and 10 Stereotactic Radiation Surgery patients, respectively, and SGPS was performed on an additional 60 breast cancer patients. All were performed IGRT using CBCT or OBI. Position error of 6 degrees of freedom was obtained using Auto-Matching System, and comparison and analysis were performed using Offline-Review in the treatment planning system. Result: The difference between the root mean square (RMS) of SGPS and LBPS in prostate cancer patients was Vrt -0.02cm, Log -0.02cm, Lat 0.01cm, Pit -0.01°, Rol -0.01°, Rtn -0.01°, SRS patients was Vrt 0.02cm, Log -0.05cm, Lat 0.00cm, Pit -0.30°, Rol -0.15°, Rtn -0.33°. there was no significant difference between the two regions. According to the IGRT standard of breast cancer patients, RMS was Vrt 0.26, Log 0.21, Lat 0.15, Pit 0.81, Rol 0.49, Rtn 0.59. Conclusion:. As a result of this study, the position error value of SGPS compared to LBPS did not show a significant difference between prostate cancer patients and SRS patients. In the case of additionally performed SGPS breast cancer patients, the position error value was not large based on IGRT. Therefore, it is considered that it will be useful to replace LBPS with SGPS, which has the great advantage of not requiring patient skin marking..

The Dose Distribution of Arc therapy for High Energy Electron (고에너지 전자선 진자조사에 의한 선량분포)

  • Chu, S.S.;Kim, G.E.;Suh, C.O.;Park, C.Y.
    • Radiation Oncology Journal
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    • v.1 no.1
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    • pp.29-36
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    • 1983
  • The treatment of tumors along curved surfaces with stationary electron beams using cone collimation may lead to non-uniform dose distributions due to a varying air gap between the cone surface and patient. For large tumors, more than one port may have to be used in irradiation of the chest wall, often leading to regions of high or low dose at the junction of the adjacent ports. Electron-beam arc therapy may elimination many of these fixed port problems. When treating breast tumors with electrons, the energy of the internal mammary port is usually higher than that of the chest wall port. Bolus is used to increase the skin dose or limit the range of the electrons. We invertiaged the effect of various arc beam parameters in the isodose distributions, and combined into a single arc port for adjacent fixed ports of different electron beam eneries. The higher fixed port energy would be used as the arc beam energy while the beam penetration in the lower energy region would be controlled by a proper thickness of bolus. We obtained the results of following: 1. It is more uniform dose distribution of electron to use rotation than stationary irradiation. 2. Increasing isocenter depth on arc irradiation, increased depth of maximum dose, reduction in surface dose and an increasing penetration of the linear portion of the curve. 3. The deeper penetration of the depth dose curve and higher X-ray background for the smaller field sized. 4. If the isocenter depth increase, the field effect is small. 5. The decreasing arc beam penetration with decreasing isocenter depth and the isocenter depth effect appears at a greater depth as the energy increases. 6. The addition of bolus produces a shift in the penetration that is the same for all depths leaving the shape of the curves unchanged. 7. Lead strips 5 mm thick were placed at both ends of the arc to produce a rapid dose drop-off.

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Interleukin-10 Polymorphisms in Association with Prognosis in Patients with B-Cell Lymphoma Treated by R-CHOP

  • Kim, Min Kyeong;Yoo, Kyong-Ah;Park, Eun Young;Joo, Jungnam;Lee, Eun Young;Eom, Hyeon-Seok;Kong, Sun-Young
    • Genomics & Informatics
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    • v.14 no.4
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    • pp.205-210
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    • 2016
  • Interleukin-10 (IL10) plays an important role in initiating and maintaining an appropriate immune response to non-Hodgkin lymphoma (NHL). Previous studies have revealed that the transcription of IL10 mRNA and its protein expression may be infl uenced by several single-nucleotide polymorphisms in the promoter and intron regions, including rs1800896, rs1800871, and rs1800872. However, the impact of polymorphisms of the IL10 gene on NHL prognosis has not been fully elucidated. Here, we investigated the association between IL10 polymorphisms and NHL prognosis. This study involved 112 NHL patients treated at the National Cancer Center, Korea. The median age was 57 years, and 70 patients (62.5%) were men. Clinical characteristics, including age, performance status, stage, and extra-nodal involvement, as well as cell lineage and International Prognostic Index (IPI), were evaluated. A total of four polymorphisms in IL10 with heterozygous alleles were analyzed for hazard ratios of overall survival (OS) and progression-free survival (PFS) using Cox proportional hazards regression analysis. Diffuse large B-cell lymphoma was the most common histologic type (n = 83), followed by T-cell lymphoma (n = 18), mantle cell lymphoma (n = 6), and others (n = 5). Cell lineage, IPI, and extra-nodal involvement were predictors of prognosis. In the additive genetic model results for each IL10 polymorphism, the rs1800871 and rs1800872 polymorphisms represented a marginal association with OS (p = 0.09 and p = 0.06) and PFS (p = 0.05 and p = 0.08) in B-cell lymphoma patients treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). These findings suggest that IL10 polymorphisms might be prognostic indicators for patients with B-cell NHL treated with R-CHOP.

A Study on the Correlation between the Childhood Linguistic Development and Family Fostering Environment (아동의 언어발달과 가정의 양육환경과의 관계)

  • Lee, Jin-Hee
    • The Korean Journal of Rehabilitation Nursing
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    • v.2 no.2
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    • pp.234-242
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    • 1999
  • The meaning of the study is in the following points. The first is to find the linguistic development of children through IQ test. The second is to find the family fostering factor for the linguistic development. For these meaning this study will have the following aims. 1) To judge the similarly agreement between the children lexical ability with the teachers evaluation to the children. 2) To compare the gender differences of lexical abilities between the urban with the rural. 3) To find the family fostering factors for the children linguistic development. The collection data has been from April 13, 1999 to April 27. The subjects for this study were two grade of elementary school, which is located in "K" city and "O"rural a chosen students(273), teachers(5), parents(176). The instruments used for this study were IQ test by Korea Behavioral Science institute and family fostering environment 25 items. Teachers linguistic evaluation. The data analysis was done using Pearson's Correlation Coefficient, t-test, ANOVA using SPSS/pc program. This study found following results. 1) The similarly agreement degree between children lexical abilities with teachers comprehending evaluation maler r= .745, female r=0.809 The similarly agreement degree between children lexical abilities with teachers expressing evaluation, male r= .657, female r= .797(P<.01) 2) In comparing of the gender difference of urban, the femail is a little high than male(t= .5065), but the especial point is more large difference in male than in female. In comparing of the gender difference of rural, the female is especial high than the male(t=-4.411). (P<.01) 3) The higher factor of influencing the linguistic development is the breast-feeding(r=-.3279) in all the gender(P<.01), So that the brast-feeding better than cow's milk, mother better than the other family members in feeding, 6~8months better than one or two years in feeding term.

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A Study of the Young Aged Women′s Bust (청년기 여성의 상반신 체형 연구)

  • 엄정옥;문명옥
    • Journal of the Korean Society of Costume
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    • v.50 no.5
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    • pp.117-130
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    • 2000
  • The purpose of this thesis is to offer basic data for clothing design which is intended to apply appropriate shape and capacity to clothes. The following are the analyzed results of an investigation which was conducted to characterize the upper half of the female body of 193 women whose ages are 18 to 25, taking part in this investigation. According to the results of analyzing young women's bust, I came to find a large individual difference of the wide varying factor numbers at the items of the side feature, the body stance, and the dart quantity. For the analysis of the female's upper body, 11 factors are used. The are as follows: Factor 1. width of the bust Factor 2. height of the bust and length of the arm Factor 3. side thickness of the bust and the upside type Factor 4. length of the bust on the front Factor 5. length of the bust on the back Factor 6. salient ratio of the breast Factor 7. width of the neck. the armhole, and measurement of the droop Factor 8. length of the shoulder Factor 9. flat ratio of the bust Factor 10. inclination of the shoulder factor 11. form of the back The shape of young women's upper bodies can be divided into four groups. The character ization of each group are as follows : Group 1 . 28.5% of the women who take part in this investigation belong to Group 1 These women have the shortest body, with a longer length of the front than the back and more thickness on the front than the back. Group 2. 21.1% of the women who take part in this investigation belong to this group. They show a longer length of the back and more thickness of the back than the front. In addition, this group is bent forward. Group 3. This group is the mast common type, showing the shortest and thickest character. 37.8% of the women who take part in this investigation have this bust character Group 4. 12.4% of the women belong to Group 4. They possess the highest and fattest character, skewing smaller necks, armholes, and waists than the other groups. This group also shows the drooping shoulders.

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Venlafaxine for Management of Hot Flashes: A Review of Randomized Controlled Trials in Human (Venlafaxine의 안면홍조 증상개선효과에 대한 최근 연구 고찰)

  • Lee, Yu-Jeung
    • Korean Journal of Clinical Pharmacy
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    • v.20 no.2
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    • pp.138-144
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    • 2010
  • The results from eight randomized controlled studies demonstrate that venlafaxine is effective in the treatment of hot flashes with tolerable adverse effects. Based on the results of the above studies, venlafaxine can be recommended for the treatment of hot flashes. However, there are limitations in the above studies. The inclusion criteria of 5 studies reviewed in this paper was breast cancer patients, so it's hard to apply the results to the general population in clinical practice. Also 5 studies had less than 100 subjects included, and 18-week study was the longest one among studies reviewed in this paper. Therefore, large and long-term clinical studies with the general population should be conducted to use venlafaxine for the treatment of hot flashes in clinical practice.

The Spatial Distribution of Quercus mongolica and Its Association with Other Tree Species in Two Quercus mongolica Stands in Mt. Jiri, Korea

  • Jang, Woong-Soon;Park, Pil-Sun;Han, Ah-Reum;Kim, Kyung-Youn;Kim, Myung-Pil;Park, Hak-Ki
    • Journal of Ecology and Environment
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    • v.33 no.1
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    • pp.67-77
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    • 2010
  • Stand structure and spatial associations of the dominant tree species in Quercus mongolica stands were investigated to understand interspecific relationships and the persistent dominance of Q. mongolica. We examined the species composition, DBH (diameter at breast height) distribution, and spatial distribution of trees (${\geq}\;2.5\;cm$ DBH) in two permanent $100\;m\;{\times}\;100\;m$ plots in Q. mongolica-dominant stands on the western part of Mt. Jiri. Ripley's K-function was used to characterize the spatial patterns and associations of dominant tree species. Q. mongolica showed a continuous and reverse-J shaped DBH distribution with clumped spatial distribution in both study sites. Q. mongolica and Abies koreana exhibited a negative association implying potential interspecific competition. The positive spatial association between Q. mongolica and Alnus hirsuta var. sibirica and Fraxinus sieboldiana were affected by site characteristics: limited habitat conditions with a large proportion of rock surface. Our results suggest that interactions among species were complex and ranged from positive to negative. Differences in stand and site characteristics and regeneration mechanisms among the species play an important role in regulating their spatial distribution patterns, while competition between individuals also contributes to spatial patterning of these communities. The high density and the early developmental stage of spatial distribution and structural characteristics of Q. mongolica and the relatively low importance values of other species in the stands imply that Q. mongolica will remain dominant in the study sites in the near future.