• 제목/요약/키워드: Lardizabalaceae

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Structure-Activity Relationship of Oleanane Disaccharides isolated from Akebia quinata on Both Cytotoxicity against Cancer Cells and NO inhibition against LPS-induced Macrophage 264.7

  • Jung, Hyun-Ju;Lee, Jung-Ok;Lee, Kyung-Tae;Choi, Jong-Won;Park, Hee-Juhn
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.371.3-372
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    • 2002
  • We have reported cytotoxicities based on several types of sugar linkage in saponins in addition to antitumor and antiinflammatory effects. In order to find further structure-activity relationship on the cytotoxicity of saponins. we intended to isolate oleanane disaccharides Irom the saponin-containing extract of Akebia Quinata (Lardizabalaceae). (omitted)

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전남지역 한약자원식물 수집분류 및 이용체계에 관한 연구 |. 모후산 한약자원 식물분포조사 (A Study on the Herb plant Resources in Mohu Mountain I. Investigation of the Herb plant Resources around Mt. Mohu)

  • 이종일
    • 한국자원식물학회지
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    • 제1권1호
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    • pp.23-32
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    • 1988
  • 전남지역에서 3대 명산중의 하나인 모후산 지역에 분포되어 있는 한약자원식물을 수집 및 분류하여 약용작물로 재배하기 위한 기초자료로 활용하고자 이 지역의 한약자원 식물의 분류를 조사한 결과는 다음과 같았다. $\bullet$ 모후산에 분포되어 있는 한약자원 식물은 58과 230종으로 분류되었다. $\bullet$ 분류수종중 초본류는 질경이, 차조기, 쇠무릎, 우엉, 사삼, 반하, 하수오, 결명자, 용담초, 맥문동, 하고초, 산삼, 도라지, 둥글레, 참마, 칡, 대계등 17종과 대본류는 인동초, 참으아리, 방기, 목퉁, 엄나무, 구기자, 산수유, 밤나무, 매화, 인진호, 희첨, 지유, 초오등 13종이 한약재료로 많이 사용되는 것들이었다.

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Quantitative Determination of Compounds from Akebia quinata by High-Performance Liquid Chromatography

  • Yen, Nguyen Thi;Thu, Nguyen Van;Zhao, Bing Tian;Lee, Jae Hyun;Kim, Jeong Ah;Son, Jong Keun;Choi, Jae Sui;Woo, Eun Rhan;Woo, Mi Hee;Min, Byung Sun
    • Bulletin of the Korean Chemical Society
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    • 제35권7호
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    • pp.1956-1964
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    • 2014
  • To provide the scientific corroboration of the traditional uses of Akebia quinata (Thunb.) Decne., a detailed analytical examination of A. quinata stems was carried out using a reversed-phase high performance liquid chromatography (RP-HPLC) method coupled to photodiode array detector (PDA) for the simultaneous determination of four phenolic substances; cuneataside D (1), 2-(3,4-dihydroxyphenyl)ethyl-O-${\beta}$-D-glucopyranoside (2), 3-caffeoylquinic acid (3) and calceolarioside B (4). Particular attention was focused on the main compound, 3-caffeoylquinic acid (3), which has a range of biological functions. In addition, 2-(3,4-dihydroxyphenyl)ethyl-O-${\beta}$-D-glucopyranoside (2) was considered as a discernible marker of A. quinata from its easy confuse plants. The contents of compounds 2 and 3 ranged from 0.72 to 2.68 mg/g and from 1.66 to 5.64 mg/g, respectively. The validation data indicated that this HPLC/PDA assay was used successfully to quantify the four phenolic compounds in A. quinata from different locations using relatively simple conditions and procedures. The pattern-recognition analysis data from 53 samples classified them into two groups, allowing discrimination between A. quinata and comparable herbs. The results suggest that the established HPLC/PDA method is suitable for quantitation and pattern-recognition analyses for a quality evaluation of this medicinal herb.