• 제목/요약/키워드: Lactuca raddeana

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Phytochemical Analysis of the Phenolic Fat-Suppressing Substances in the Leaves of Lactuca raddeana in 3T3-L1 Adipocytes

  • Nugroho, Agung;Choi, Jae Sue;An, Hyo-Jin;Park, Hee-Juhn
    • Natural Product Sciences
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    • 제21권1호
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    • pp.42-48
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    • 2015
  • Lactuca raddeana (Compositae) is used to treat obesity and complications due to diabetes. The five phenolic compounds including chlorogenic acid, chicoric acid, luteolin 7-O-glucoside, luteolin 7-O-glucuronide, luteolin were qualitatively identified by LC-ESI-MS analysis. The contents were quantitatively determined by HPLC, under the condition of a Capcell Pak C18 column ($5{\mu}m$, $250mm{\times}4.6mm\;i.d.$) and a gradient elution of 0.05% trifluoroacetic acid (TFA) and 0.05% TFA in $MeOH-H_2O$ (60 : 40). The contents of chicoric acid (100.99 mg/g extract) and luteolin 7-O-glucoside (101. 69 mg/g extract) were high, while those of other three phenolic substances were very low. The 3T3-L1 adipocyte cells treated with chicoric acid and luteolin 7-O-glucuronide significantly suppressed the accumulation of fat, suggesting they are effective against obesity. Since high level of peroxynitrite (ONOO) causes cardiovascular disease in obese patients, its scavenging activity was also studied.

산씀바귀의 Triterpenoid 성분조성 (Triterpenoid constituents of the Herbs of Lactuca raddeana)

  • 박희준;윤세영;곽태순;최재수;박종희
    • 한국약용작물학회지
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    • 제3권2호
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    • pp.151-155
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    • 1995
  • 국화과 식물인 산씀바귀(Lactuca raddeana)를 식물화학적 방법에 의하여 연구한 바 primaylong chain alcohol인 1-hexacosanol과 1-tetracosa not을, triterpene acetate로 ${\beta}-amyrin\;acetate,\;{\alpha}-amyrin acetate$, lupeol acetate, pseudotaraxasterol acetate, taraxasterol acetate 및 germanicol acetate등을, fatty acyl triterpene은 이들의 구성 triter pone alcohol이 triterpone acetate의 경우와 같았으며 acyl moiety는 myristate, palmitate, stearate및 arachidate로 각각 나타났다.

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전라남도 일부지역 대규모 절토비탈면의 식물침입 (Plants Invasion in Large-scale Cutting Slopes in the Part of Jeollanamdo)

  • 박문수
    • 한국환경복원기술학회지
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    • 제8권4호
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    • pp.32-42
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    • 2005
  • To investigate the plants invasion process and dominant species in large-scale cutting slopes, slopes elapsed one year to thirteen years after construction had been selected in five counties. The obtained results are summarized as follows : The species of high appearance frequency were Alnus firma, Arundinella hirta, Miscanthus sinensi var. purpurascens, Erigeron cancdensis, Artemisia princeps var. orientalis, Oenothera odorata, Lactuca raddeana, Lactrca indica var. laciniata, Lespedeza bicolor, Youngia sonchifolia, Populus albaglandulosa, and so on. The biological type of identified vascular plants was $Ch-D_1-R_{5-e}$. In time, plant coverage was increased gradually and average of plant coverage was 1.17% in slopes which elapsed one year, 42.44% after six years, 56.67% after eight years, and 69.17% after ten years. The dominant species in the surveyed slopes were covered with Alnus firma, Artemisia princeps var. orientalis, Erigeron cancdensis, Miscanthus sinensi var. purpurascens, Arundinella hirta, Lactuca raddeana, Oenothera odorata, Boehmeria spicata, Kummerowia striata and Artemisia montana of the 59 species. The conditions of location in large-scale cutting slopes are hard to fix and germinate of seeds, and extend plant roots in the slope soil. Hence, the highly appearance species and dominance species of the area will make plant coverage quick and slope stable.

Phytochemical constituents of Lactuca serriola leaves and their content analysis by HPLC-UV

  • Kim, Juree;Lee, Hak-Dong;Choi, Jungwon;Lee, Sanghyun
    • Journal of Applied Biological Chemistry
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    • 제65권3호
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    • pp.153-158
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    • 2022
  • This study aimed to identify the phytochemical constituents of Lactuca serriola leaves and perform quantitative analysis of the methanol (MeOH) extract of L. serriola, L. indica, L. raddeana, L. sativa, and L. triangulata. Six compounds were isolated from the MeOH extracts of L. serriola using open column chromatography and identified as protocatechuic acid (1), caffeic acid (2), cynaroside (3), apigenin 7-glucuronide (4), luteolin (5), and apigenin (6) using 1H-, 13C-nuclear magnetic resonance, and mass spectrometry. Quantitative analysis of the six compounds was performed on the MeOH extract of Lactuca species using high-performance liquid chromatography (HPLC) and an ultraviolet (UV). A reverse-phased column was used, and the UV absorbance was set to 280 nm. The contents of compounds 2 and 3 were the highest (1.58 and 2.64 mg/g ext., respectively) in L. serriola extracts. However, compounds 4 and 6 were higher (1.46 and 0.40 mg/g ext., respectively) in L. triangulata. These results provide quantitative data for the application of Lactuca species in the pharmaceutical and functional food industries.