• Journal of Food Hygiene and Safety
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• v.37 no.5
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• pp.297-305
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• 2022

Antioxidants are food additives that extend the shelf life of food products by preventing lipid rancidity caused by active oxygen. They can either be naturally-derived or manufactured synthetically via chemical synthesis. In this study, method validation of five synthetic antioxidants, namely butylated hydroxyanisole, butylated hydroxytoluene, tertiary butylhydroquinone, propyl gallate, and disodium ethylenediaminetetraacetic acid, was performed using a high performance liquid chromatography-ultraviolet visible detector, and the method applicability was evaluated by analyzing foods containing antioxidants. The coefficient of determination (R²) average was 0.9997, while the limit of detection and limit of quantification were 0.02-0.53 and 0.07-1.61 mg/kg, respectively. The intra and inter-day accuracies and precisions were 83.2±0.7%-98.7±2.1% and 0.1%-5.7% RSD, respectively. Inter-laboratory validation for accuracy and precision was conducted using the Food Analysis Performance Assessment Scheme quality control material. The results satisfied the guidelines presented by the AOAC International. In addition, the expanded uncertainty was less than 16%, as recommended by CODEX. Consequently, to enhance public health safety, the results of this study can be used as basis data for evaluating the intake of synthetic antioxidants and assessing their risks in Korea.

• Journal of the Korea institute for structural maintenance and inspection
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• v.24 no.2
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• pp.33-40
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• 2020

Various studies have been conducted on the structural health monitoring using optical fiber. Optical fibers can be used to measure multiple and distributed strain. Among the optical fiber sensors, FBG sensor has advantages of dynamic response measurement and high precision, but the number of measurement points is limited. Distributed fiber sensors, represented by distributed Brillouin sensors, usually have more than 1000 measurement points, but the low sampling rate makes dynamic measurements impossible. In this study, a hybrid nerve sensor system using only the advantages of the FBG sensor and the distributed Brillouin sensor has been proposed. Laboratory experiments were performed to verify the proposed system, and the accuracy and reproducibility were verified by comparing with commercial sensors. Applying the proposed system, dynamic response ambient measurements are used to evaluate the global state of the structure. When an abnormal condition is detected, the local condition of the structure is evaluated by static response measurement using the distributed measurement system. The proposed system can be used for efficient structural health monitoring.

• Proceedings of the Korea Institute of Fire Science and Engineering Conference
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• 2013.04a
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• pp.41-41
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• 2013

화학산업이 발달함에 따라 화학 산업 현장에서 사용되고 있는 가연성물질들의 여러 가지 화재 및 폭발 위험이 증가되고 있으며, 화재 및 폭발의 예방 안전을 위한 화학공정설계 및 대처에 있어, 물질의 연소특성치 데이터를 필요로 한다. 인화점은 가연성 액체를 다루는 공정에서 안전한 취급과 사고방지를 위해 중요한 자료가 되며, 화재의 위험을 나타내는 지표로서 가연성액체의 액면 가까이서 인화할 때 필요한 증기를 발산하는 액체의 최저온도, 그리고 가연성증기의 포화증기압이 공기와 혼합기체의 폭발한계 하한농도와 같게 되는 온도로 정의한다. 본 연구에서는 2성분계 혼합물에 대해 인화점을 측정하였고, 측정값을 Raoult의 법칙과 다중회귀분석(Multiple Regression)을 도입하여 이론값과 비교 하였다. 따라서 본 연구에서 제시된 방법론에 의해 아직까지 밝혀지지 않은 순수가연성액체와 가연성혼합물의 인화점을 예측하는 방법을 전개하고자 하며, 실험에서 찾고자하는 자료에 도움을 주고자 한다. 본 연구를 바탕으로 혼합물의 인화점 예측 방법과 실험에서 측정한 자료를 화재 및 폭발을 방지하는 기초 자료로 제공하고자하며, 산업현장에서 취급되고 있고 위험성 평가가 되지 않은 보다 많은 물질에 대한 이론 및 실험 연구에 활용 되도록 하는데 그 목적이 있다.

• Journal of the Korean Institute of Gas
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• v.17 no.6
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• pp.67-72
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• 2013

The flash point is the lowest temperature at which there is enough concentration of flammable vapor to form an ignitable mixture with air. The flash point is a major physical property used to analyse the fire and explosion hazards of a flammable liquid solution. The flash point data for pure components are easily available in several literature. But the flash points of the flammable binary solutions appear to be scarce in the literature. The objective of this study is to measure and estimate the flash point of acetic acid-formic acid system. Cleveland open cup tester was used to measure the flash point. The experimental data were compared with the values estimated by the Raoult's law and the optimization methods based on van Laar and Wilson equations. As a result, the estmated values by optimization methods were found to be better than those based on the Raoult's law.

• Journal of Preventive Medicine and Public Health
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• v.31 no.3 s.62
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• pp.414-423
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• 1998

Metal fume fever has been known as an occupational disease is induced by intense inhalation of fresh metal fume with a particle size smaller than $0.5{\mu}m\;to\;1{\mu}m$. The fumes originate from heating metals beyond their boiling point, as happens, for example, in welding operations. Oxidation usually accompanies this process. In most cases, this syndrome is due to exposure to zinc oxide fumes; however, other metals like copper, magnesium, cadmium, manganese, and antimony are also reported to produce such reactions. Authors report a case of metal fume fever suspected to be associated with copper fume inhalation. The patient was a 42-year-old male and was a smoker. He conducted inert gas tungsten arc welding on copper-coated materials without safety precautions such as a protective mask and adequate ventilation. Immediately after work, he felt metallic taste in his mouth. A few hours after welding, he developed headache, chilling sensation, and chest discomfort. He also complained of myalgia, arthralgia, feverish sensation, thirst, and general weakness. Symptoms worsened after repeated copper welding on the next day and subsided gradually following two weeks. Laboratory examination showed a transient increase of neutrophil count, eosinophilia, elevated erythrocyte sedimentation rate, and positive C-reactive proteinemia. Blood and urine copper level was also increased compared to his wife. Before this episode, he experienced above complaints several times after welding with copper materials but welding of other metals did not produce any symptoms. It was suggested that copper fume would have induced metal fume fever in this case. Further investigations are needed to clarify their pathogenic mechanisms.

• Proceedings of the Korea Society of Poultry Science Conference
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• 2006.11a
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• pp.7-16
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• 2006

Poultry products including meat and eggs constitute a major protein source in the American diet and disease - causing pathogens represent major challenges to the poultry industry. More than 95 % of pathogens enter the host through the mucosal surfaces of the respiratory, digestive and reproductive tracts and over the past few decades, the two main mechanisms used to control diseases have been the use of vaccines and antibiotics. However, in the poultry industry, there are mounting concerns over the ability of current vaccines to adequately protect against emerging hyper - virulent strains of pathogens and a lack of suitable, cost effective adjuvants. Thorough investigation of the immunogenetic responses involved in host-pathogen interactions will lead to the development of new and effective strategies for improving poultry health, food safety and the economic viability of the US poultry industry. In this paper, I describe the development of immunogenomic and proteomic tools to fundamentally determine and characterize the immunological mechanisms of the avian host to economically significant mucosal pathogens such as Eimeria. Recent completion of poultry genome sequencing and the development of several tissue-specific cDNA libraries in chickens are facilitating the rapid application of functional immunogenomics in the poultry disease research. Furthermore, research involving functional genomics, immunology and bioinformatics is providing novel insights into the processes of disease and immunity to microbial pathogens at mucosal surfaces. In this presentation, a new strategy of global gene expression using avian macrophage (AMM) to characterize the multiple pathways related to the variable immune responses of the host to Eimeria is described. This functional immunogenomics approach will increase current understanding of how mucosal immunity to infectious agents operates, and how it may be enhanced to enable the rational development of new and effective strategies against coccidiosis and other mucosal pathogens.

• Journal of the Korean Institute of Gas
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• v.16 no.5
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• pp.41-46
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• 2012

The flash point the lowest temperature at which the concentration of vapor of the substance in the air reaches the lower flammability limit(LFL), and is one of the most important physical properties used to determine the potential for fire and explosion hazards of industrial materials. The most published flash point data was for pure components and the flash points of the binary solutions that have flammable components, appear to be scarce in the literature. In the present study, the flash points of tert-pentanol+n-decane system were measured by Tag open-cup tester. The measured data were compared with the values calculated by the Raoult's law and the optimization methods based on the Wilson and NRTL equations. The calculated values by optimization methods were found to be better than those based on the Raoult's law.

• Journal of Korean Society for Atmospheric Environment
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• v.34 no.3
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• pp.447-456
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• 2018

Elemental carbon (EC) and organic carbon (OC) thermal/optical methods for the analysis of ambient particulate matter were used to analyze twenty-two $PM_{2.5}$ samples along collected from May 28 to June 20 of 2016 at the Anmyeon measurement site ($36.32^{\circ}N$; $126.19^{\circ}E$). The three laboratory OCEC protocols, which are the National Institute of Occupational Safety and Health (NIOSH5040), the Interagency Monitoring of Protected Visual Environments_A(IMPROVE_A), and European Supersites for Atmospheric Aerosol Research2 (EUSAAR2), were utilized for the aerosol characterization experiment as in intercomparisons between three protocols. There are excellent agreement for total carbon (i.e. sum of EC and OC), but statistically significant differences were observed in the split between the measured EC and OC. IMPROVE_A EC values were always larger than both NIOSH5040 and EUSAAR2 protocols. These methods exhibited significantly different temperature-distributions based on thermogram analysis, which is normalized to total carbon. In this study, a protocol for carbonaceous analysis is suggested for the Korean Peninsula.

• Journal of the Korean Institute of Gas
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• v.22 no.2
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• pp.52-58
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• 2018

The flash point is one of the most important properties to characterize fire and explosion hazard of flammable liquid mixture. In this paper, the flash points of ternary liquid mixture, n-nonane+n-decane+n-tridecane system, were measured using Seta flash closed cup tester. The measured values were compared with the calculated values using Raoult's law and multiple regression analysis. The absolute average errors(AAE) of the results calculated by Raoult's law is $0.6^{\circ}C$. The absolute average errors of the results calculated by multiple regression analysis is $0.4^{\circ}C$. As can be seen from AAE, the calculated values based on multiple regresstion analysis were found to be better than those based on Raoult's law.

• Journal of Microbiology and Biotechnology
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• v.25 no.12
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• pp.2043-2048
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• 2015

Bacillus thuringiensis microbial insecticide products have been applied worldwide. Although a few cases of B. thuringiensis foodborne illness have been reported, little is known about the toxigenic properties of B. thuringiensis isolates. The aims of this study were to estimate the pathogenic potential of B. thuringiensis selected from microbial insecticide products, based on its possession of toxin genes and production of enterotoxins. Fifty-two B. thuringiensis strains selected from four kinds of microbial insecticide products were analyzed. PCR assay for detection of toxin genes and immunoassay for detection of enterotoxins were performed. The hemolysin BL complex as a major enterotoxin was produced by 17 (32.7%), whereas the non-hemolytic enterotoxin complex was detected in 1 (1.9%) of 52 B. thuringiensis strains. However, cytK, entFM, and ces genes were not detected in any of the tested B. thuringiensis strains. The potential risk of food poisoning by B. thuringiensis along with concerns over B. thuringiensis microbial insecticide products has gained attention recently. Thus, microbial insecticide products based on B. thuringiensis should be carefully controlled.