• 제목/요약/키워드: Laboratory Chamber test

검색결과 98건 처리시간 0.025초

Stability Test and Quantitative and Qualitative Analyses of the Amino Acids in Pharmacopuncture Extracted from Scolopendra subspinipes mutilans

  • Cho, GyeYoon;Han, KyuChul;Yoon, JinYoung
    • 대한약침학회지
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    • 제18권1호
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    • pp.44-55
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    • 2015
  • Objectives: Scolopendra subspinipes mutilans (S. subspinipes mutilans) is known as a traditional medicine and includes various amino acids, peptides and proteins. The amino acids in the pharmacopuncture extracted from S. subspinipes mutilans by using derivatization methods were analyzed quantitatively and qualitatively by using high performance liquid chromatography (HPLC) over a 12 month period to confirm its stability. Methods: Amino acids of pharmacopuncture extracted from S. subspinipes mutilans were derived by using O-phthaldialdehyde (OPA) & 9-fluorenyl methoxy carbonyl chloride (FMOC) reagent and were analyzed using HPLC. The amino acids were detected by using a diode array detector (DAD) and a fluorescence detector (FLD) to compare a mixed amino acid standard (STD) to the pharmacopuncture from centipedes. The stability tests on the pharmacopuncture from centipedes were done using HPLC for three conditions: a room temperature test chamber, an acceleration test chamber, and a cold test chamber. Results: The pharmacopuncture from centipedes was prepared by using the method of the Korean Pharmacopuncture Institute (KPI) and through quantitative analyses was shown to contain 9 amino acids of the 16 amino acids in the mixed amino acid STD. The amounts of the amino acids in the pharmacopuncture from centipedes were 34.37 ppm of aspartate, 123.72 ppm of arginine, 170.63 ppm of alanine, 59.55 ppm of leucine and 57 ppm of lysine. The relative standard deviation (RSD %) results for the pharmacopuncture from centipedes had a maximum value of 14.95% and minimum value of 1.795% on the room temperature test chamber, the acceleration test chamber and the cold test chamber stability tests. Conclusion: Stability tests on and quantitative and qualitative analyses of the amino acids in the pharmacopuncture extracted from centipedes by using derivatization methods were performed by using HPLC. Through research, we hope to determine the relationship between time and the concentrations of the amino acids in the pharmacopuncture extracted from centipedes.

모형챔버시험을 이용한 사질토 지반의 경량포장체용 기초의 하중전달 특성 (Load Transfer Characteristics of Pile Foundation for Lightweight Pavement in Sand Soil using Laboratory Chamber Test)

  • 신광호;황철비;전상렬;이관호
    • 한국산학기술학회논문지
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    • 제15권7호
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    • pp.4588-4594
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    • 2014
  • 본 연구에서는 연약지반에서의 경량콘크리트포장을 적용할 때의 안전성 평가를 위해 실제 포장체 사이즈의 1/30으로 축소한 모형을 이용하여 모래지반에서 실험을 실시하였다. 모형토조를 이용하여 지반을 조성하였고, 표준 말뚝재하시험(완속재하시험방법)을 이용하였다. 수직하중이 적용되는 말뚝기초의 슬래브의 중심에서 가까운 순으로 Case A, Case B, Case C로 구분하였고, 각각의 말뚝의 간격은 8cm로 하였다. 말뚝기초 모형시험결과 사질토지반에서 수직하중을 1.5kg에서 12kg로 증가시킬 때 포장체가 전체적으로 침하하였고, 최대 침하량은 0.4mm로 측정되었다. Case A의 경우 압축력을 받는 것으로 나타났으며, Case B는 수직하중이 증가함에 따라 말뚝에 압축력과 함께 인장력도 같이 받는 것으로 보이며, Case C는 하중단계가 증가할수록 인장변형이 증가하는 경향을 나타내었다.

순환골재 다공질 콘크리트말뚝에 의한 압밀촉진효과에 관한 고찰 (A Study on the Effect of Promoting Consolidation by Recycled-Aggregate Porous Concrete Pile)

  • 유승경
    • 한국지반신소재학회논문집
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    • 제8권4호
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    • pp.35-40
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    • 2009
  • 본 논문에서는 순환골재 다공질 콘크리트말뚝(RAPP : Recycled-Aggregate Porous Concrete Pile)에 의한 압밀촉진효과를 파악하기 위하여 일련의 실내모형실험을 수행하였다. 본 연구에서 얻어진 실험 결과를 동일한 조건에서 수행한 모래다짐말뚝과 쇄석다짐말뚝에 대한 기존의 실험결과(유승경, 2009)와 비교하여 RAPP로 개량된 복합지반의 시간에 따른 침하량의 변화 특성과 압밀시간에 대하여 비교, 분석하였다. 또한 일련의 수치해석을 수행하여 실내모형실험 결과를 평가하였다. 분석 결과로부터 RAPP에 의한 일차압밀과 이차압밀에 대한 침하저감효과가 타 공법에 비해 탁월함을 알 수 있었으며 압밀 종료시간도 상대적으로 빠르게 나타나 RAPP에 의한 압밀촉진효과가 우수함을 입증할 수 있었다.

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흡입독성평가를 위한 비부노출 챔버의 유동흐름 특성 (Characteristics of flow field of nose-only exposure chamber for inhalation toxicity evaluation)

  • 노학재;봉춘근;봉하경;김용구;조명행;김상화;김대성
    • 한국입자에어로졸학회지
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    • 제12권1호
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    • pp.1-9
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    • 2016
  • In this work, we evaluated the characteristics of flow field and uniformity of the nose-only exposure chambers for the inhalation toxicity test. Computational fluid dynamics (CFD) modeling was carried out to demonstrate uniformity of the nose-only exposure chambers. Because it is very important in the inhalation toxicity experiments that test materials are distributed uniformly to each holder of the chamber. The test was done with these 3 types of chamber with different form to develop inhalation toxicity evaluation system, easy-to-operate system among exposure chamber used for evaluating inhalation toxicity of environmental chemical mixtures. Through CFD interpretation, nose-only exposure chamber was made with the selection of the optimal conditions. For its evaluation, one type of fragrance was selected and measured particle size distribution of each port. The gene becoming luminous to green fluorescence was combined with GPT-SPE, a type of tGFP vector, to be inhaled to the mouse. Based on this, luminous intensity was checked. As a result, total particle number concentration of each port had average value of $3.17{\times}10^6{\sharp}/cm^3$ and range of the highest and lowest concentration value was approximately ${\pm}4.8%$. Autopsy of lung tissues of mouse showed that it had clearly better delivery of gene compared to the control group.

Effects of External PIM Sources on Antenna PIM Measurements

  • Kim, Jin-Tae;Cho, In-Kui;Jeong, Myung-Yung;Choy, Tae-Goo
    • ETRI Journal
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    • 제24권6호
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    • pp.435-442
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    • 2002
  • Antenna Passive Intermodulation (PIM) level measurement results are rarely credited to be due to external signal receiving characteristics of the antennas or serious effects from external PIM sources, such as the anechoic chamber absorber and antenna tower. This paper presents an antenna PIM model for a reflected PIM measurement method. Based on the findings of null point generation and the behavior of the third order PIM values obtained by theoretical predictions and experimental results, we concluded that the results of the antenna PIM level test were influenced by the external PIM sources generated by the anechoic chamber absorber and the path differences of PIM signals coming into the antenna.

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Degradation of Coatings under Atmospheric Tropical Conditions

  • To, Thi Xuan Hang;Pham, Gia Vu;Vu, Ke Oanh;Trinh, Anh Truc;Kodama, Toshiaki;Tanabe, Hiroyuki;Taki, Tohru;Nagai, Masanori
    • Corrosion Science and Technology
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    • 제2권5호
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    • pp.207-211
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    • 2003
  • The weather resistance of five coatings systems based on alkyd, chlorinated rubber, epoxy, polyurethane and fluoropolymer were studied by natural exposure test and accelerated test. The coatings were exposed at Hanoi station with urban industry atmosphere and at Baichay station with marine atmosphere. The degradation of coatings was evaluated by gloss measurement and surface analysis by scanning electronic microscopy. The results obtained show that among coatings tested the gloss of polyurethane and fluoropolymer coatings remained highly and those of alkyd, chlorinated rubber and epoxy coatings were very low after two years of atmospheric exposure. Under accelerating conditions the gloss of fluoropolymer coatings remained highly after 80 cycles of testing. By comparison with accelerating test in UV-condensation chamber the conditions at atmospheric stations are more aggressive.

순환골재 다공질 콘크리트말뚝 공법에 대한 실내모형실험 (Experimental Study on Recycled-Aggregate Porous Concrete Pile Method)

  • 유승경;이창민;김세원;최항석
    • 한국지반신소재학회논문집
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    • 제7권2호
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    • pp.23-29
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    • 2008
  • 본 연구의 목적은 연약지반개량을 위한 다짐말뚝공법의 재료로써 건설폐기물에서 선별 처리된 순환골재의 적용성을 평가함과 동시에 기존 다짐말뚝공법들의 단점을 보완하는 새로운 공법을 개발하는 데 있다. 본 논문에서는 순환골재 다공질 콘크리트말뚝에 의한 지반개량효과를 분석하기 위하여 실내모형실험을 수행하였다. 실험결과로부터 개량된 복합지반의 침하량과 과잉간 극수압 및 연직응력증분의 시간에 따른 변화 특성과 복합지반의 거동 특성을 분석하였다.

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고압산소챔버 중재가 알코올에 의한 산화적 스트레스 및 숙취 해소에 미치는 영향 (Effects of Hyperbaric Oxygen Intervention on Alcohol-Induced Oxidative Stress and Hangover in Hyperbaric Oxygen Chamber)

  • 권혁찬;박순원;조현정;강지현;이현주;태기식
    • 대한의용생체공학회:의공학회지
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    • 제39권5호
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    • pp.175-182
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    • 2018
  • The purpose of this study is to evaluate the reliability and effectiveness of hyperbaric oxygen chamber on alcohol-induced oxidative stress and hangover. In order to evaluate them, 20 healthy adults were tested for blood and hangover stress tests. When an exponential change was examined after 3 interventions (hangover drink, hyperbaric oxygen chamber, and normal chamber as placebo effect) of 1 hour, the heart rate of subjects experiencing a hyperbaric oxygen chamber showed a statistically significant decrease (p < 0.001). The tests of blood alcohol concentration (BAC) as for exquisite hematology analysis, glucose, creatinine, and AST (aspartate aminotransferase) as well as ALT (alanine aminotransferase) used as liver-damage indicator show that the hyperbaric chamber has the effective effect. In the test of lactic acid, CRP (c-reactive protein), cortisol, and creatinine, the hyperbaric chamber shows much more excellent effect than the hangover drink and normal chamber as control groups. Further studies on hyperbaric oxygen chamber intervention including this study could be very helpful for improving lives of both the patients and healthy people.

포항가속기 저장링챔버의 헬륨누설검사 (Helium Leak Test for the PLS Storage Ring Chamber)

  • 최만호;김형종;최우천
    • 비파괴검사학회지
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    • 제13권3호
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    • pp.31-38
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    • 1993
  • 포항가속기 저장링 진공챔버는 진공도가 $10^{-10}Torr$로 유지될 수 있도록 설계되었고, 초고진공에 적합하도록 TIG용접을 하여 헬륨에 대한 누설률이 $1{\times}10^{-10}Torr{\cdot}{\ell}/sec$ 이하의 기밀성이 요구되고 있다. 저장링 진공챔버에 적용된 TIG용접방법과 결함에 대해 논하고 누설검사에 사용된 헬륨누설검사기의 원리 및 검사방법에 대해서 보고하고자 한다.

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모형챔버시험을 이용한 점성토 지반에 설치된 경량포장체용 기초의 하중전달 특성 (An Analysis of Pile Foundation Load Transfer for Lightweight Pavement System in Clay Soil using Lab Chamber Test)

  • 이관호;신광호
    • 대한토목학회논문집
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    • 제36권3호
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    • pp.545-550
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    • 2016
  • 본 연구에서는 말뚝기초의 실내모형시험을 통해 연약지반상의 경량포장체용 기초로서의 적합성을 분석 및 평가를 목적으로 하고 있다. 안전성 평가를 위해 실내모형시험용 경량포장체용 말뚝기초모형을 실제 포장체 사이즈의 1/30으로 축소한 모형을 이용하여 시험을 실시하였다. 지반 조건은 연약지반을 모사하여 모델링하였고, 말뚝은 마찰군말뚝으로 실험하였다. 제한된 실험으로부터 측정된 모형포장체의 침하량은 Case A는 0.86 mm, Case B는 0.70 mm, Case C는 0.50 mm로 측정되었다. 측정된 말뚝기초 모형의 실험값을 실제 크기로 환산하였을 때의 최대침하량과 부등침하량은 각각 25.8 mm와 10.8 mm로 도로교 설계기준에 의거하여 최대부등변위량인 50 mm와 부등변위량 20 mm를 넘지 않는 것으로 보이며 침하량을 기준으로 안전성을 평가 할 경우 안전한 것으로 판정되었다.