• Journal of Nutrition and Health
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• 제24권4호
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• pp.337-343
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• 1991

엽산의 항비타민제인 9-methyl folate가 흰 쥐의 엽산 대사에 미치는 영향을 조사하기 위하여, Sprague-dawley 암컷 쥐를 엽산 결핍식이군, 대조군, x-methyl folate 투여군으로 나누어 실험하였다. 9-methyl folate는 실험동물에게 엽산 결핍증을 유발시키는 x-methyl folate의 성분 가운데 주된 항비타민제이며, 본 실험에서는 식이 1kg당 5g의 x-methyl folate를 첨가하였다. x-methyl folate를 실험동물에게 먹였을 때 히스티딘의 산화속도와 간장내의 엽산 농도가 크게 저하되었으며, $[^{3}H]folate$를 복강에 투여한 후 24시간 내에 간장에 보유되는 엽산의 양도 x-methyl folate 투여군에 있어 유의적인 감소를 보였다. 이 실험 결과에서 9-methyl folate는 흰 쥐에 있어 엽산이 간으로 유입되어 보유되는 과정을 저해하므로써 간장 내의 엽산의 양을 저하시키며, 그 결과 히스티딘의 산화속도도 저하된 것으로 보인다.

• Journal of Communications and Networks
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• 제5권2호
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• pp.157-166
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• 2003

This paper deals with the problem of channel identification for Single Input Multiple Output (SIMO) slow fading channels using clustering algorithms. Due to the intrinsic memory of the discrete-time model of the channel, over short observation periods, the received data vectors of the SIMO model are spread in clusters because of the AWGN noise. Each cluster is practically centered around the ideal channel output labels without noise and the noisy received vectors are distributed according to a multivariate Gaussian distribution. Starting from the Markov SIMO channel model, simultaneous maximum ikelihood estimation of the input vector and the channel coefficients reduce to one of obtaining the values of this pair that minimizes the sum of the Euclidean norms between the received and the estimated output vectors. Viterbi algorithm can be used for this purpose provided the trellis diagram of the Markov model can be labeled with the noiseless channel outputs. The problem of identification of the ideal channel outputs, which is the focus of this paper, is then equivalent to designing a Vector Quantizer (VQ) from a training set corresponding to the observed noisy channel outputs. The Linde-Buzo-Gray (LBG)-type clustering algorithms [1] could be used to obtain the noiseless channel output labels from the noisy received vectors. One problem with the use of such algorithms for blind time-varying channel identification is the codebook initialization. This paper looks at two critical issues with regards to the use of VQ for channel identification. The first has to deal with the applicability of this technique in general; we present theoretical results for the conditions under which the technique may be applicable. The second aims at overcoming the codebook initialization problem by proposing a novel approach which attempts to make the first phase of the channel estimation faster than the classical codebook initialization methods. Sample simulation results are provided confirming the effectiveness of the proposed initialization technique.

• 한국통신학회논문지
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• 제41권7호
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• pp.816-822
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• 2016

콘텐트 기반 이미지 검색은 기존의 태그 또는 레이블이 있는 텍스트 기반의 검색이 아닌 이미지의 특징을 이용하여 검색하는 방법이다. 실생활 이미지 데이터는 태그나 레이블이 달려있는 경우가 많지 않기 때문에 텍스트 기반의 검색 방법을 사용하기 힘든 경우가 있다. 또한, 기존에 주로 사용되는 이미지 특징 벡터의 유사도를 사용하여 검색하는 방법은 추출 벡터의 유사도 기준으로 사용자가 의도한 결과가 나올지 확신할 수 없다. 예를 들어 사용자가 입력한 질의 이미지와 검색된 이미지들의 종류가 일치하는지의 문제가 있다. 본 논문에서는 사용자가 질의 이미지의 클래스를 예상하고 결과도 동일한 클래스를 원한다는 가정에 착안하여 이미지 검색 엔진의 성능을 개선하였다. 기존의 유사도 기반의 검색에 머신 러닝 기법을 사용한 이미지 분류기를 적용하여 질의와 동일한 클래스의 결과를 찾는 방법을 제안하였으며, 그 성능을 20개 카테고리에 속하는 11,530개의 이미지로 구성되어 있는 PASCAL VOC 공개 데이터를 이용하여 검증하였다.

• 대한간호학회지
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• 제34권8호
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• pp.1434-1442
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• 2004

Purpose. Professional nursing ethics is a living, dynamic set of standards for nurses' professional moral behavior. Furthermore, in daily clinical nursing training, nursing students are constantly confronted with decision-making that is moral in nature. The aim of this study was to identify the perceived ethical attitudes in the clinical training process of senior nursing students using Q-methodology to offer basic strategies for nursing ethics education and thereby improve patients' care. Methods. Q-methodology provides a scientific method for identifying perception structures that exist within certain individuals or groups. Thirty-seven participants in a university rated 38 selected Q-statements on a scale of 1-9. The collected data were analyzed using pc-QUNAL software. Results. Principal component analysis identified 3 types of ethical attitudes in nursing students in Korea. The categories were labeled Sacred-life, Science-realistic and Humane-life. Sacred-life individuals think that a life belongs to an absolute power (God), not a man, and a human life is a high and noble thing. Science-realistic individuals disagreed that allowing an induced abortion or embryo (human) duplication is unethical behavior that provokes a trend, which takes the value of a life lightly; most of them took a utilitarian position with respect to ethical decisions. Humane-life individuals exhibit a tendency toward human-centered thought with respect to ethical attitudes. Conclusion. This study will be of interest to educators of students of nursing and hospital nursing administrators. Also, the findings may provide the basis for the development of more appropriate strategies to improve nursing ethics education programs.

• 한국직업건강간호학회지
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• 제27권2호
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• pp.109-120
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• 2018

Purpose: The aims of this study were to examine the work, client, and personal environments of community health practitioners, including the level of their professional quality of life (ProQOL), and identify the factors affecting their ProQOL. Methods: Data were collected using a web-survey questionnaire, which was completed by a sample of 308 community health practitioners currently working in Korea. The questionnaire included items on ProQOL; three dimensions labeled compassion satisfaction, burn out, and secondary traumatic stress; job stress; job satisfaction; sense of community; and general characteristics. Results: The mean scores for the three dimensions were $39.2{\pm}6.44$ (compassion satisfaction), $31.9{\pm}3.59$ (burn out), and $26.4{\pm}5.05$ (secondary traumatic stress). A multiple linear regression revealed that compassion satisfaction varied significantly according to the satisfaction with job choice, sense of community, job stress, and job satisfaction. The factors affecting burn out were sense of community and work load, while the factors affecting secondary traumatic stress were education, job stress, and job satisfaction. Conclusion: The findings of this study suggest that comprehensive intervention focusing on improving the sense of community and job satisfaction and reducing job stress is essential to promote community health practitioners' ProQOL.

• Journal of Mechanical Science and Technology
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• 제17권9호
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• pp.1388-1396
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• 2003

The hydrodynamic instability of the three-dimensional boundary layer on a rotating disk introduces a periodic modulation of the mean flow in the form of stationary cross flow vortices. The instability labeled Type II by Faller occurs first at lower Reynolds number than that of well known Type I instability. Detailed numerical values of the amplification rates, neutral curves and other characteristics of the two instabilities have been calculated over a wide range of parameters. Presented are the neutral stability results concerning the two instability modes by solving the appropriate linear stability equations reformulated not only by considering whole convective terms but also by correcting some errors in the previous stability equations. The present stability results agree with the previously known ones within reasonable limit. Consequently, the flow is found to be always stable for a disturbance whose dimensionless wave number is greater than 0.75. Some spatial amplification contours have been computed for the stationary disturbance wave, whose azimuth angle $\varepsilon$= 11.29$^{\circ}$ to 15$^{\circ}$ and for the moving disturbance wave, whose azimuth angle $\varepsilon$ = 12.5$^{\circ}$ to 15$^{\circ}$. Also, some temporal amplification contours have been computed for the stationary disturbance wave, whose azimuth angle $\varepsilon$= 11.29$^{\circ}$ to 15$^{\circ}$ and for the moving disturbance wave, whose azimuth angle $\varepsilon$= 12$^{\circ}$ to 15$^{\circ}$. The flow instability was observed by using a white titanium tetrachloride gas over rotating disk system. When the numerical results are compared to the present experimental data, the numerical results agree quantitatively, indicating the existence of the selective frequency mechanism.

• International Journal of Contents
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• 제8권3호
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• pp.83-93
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• 2012

In this paper, we propose a novel method that automatically generates real character images to familiarize existing OCR systems with new fonts. At first, we generate synthetic character images using a simple degradation model. The synthetic data is used to train an OCR engine, and the trained OCR is used to recognize and label real character images that are segmented from ideal document images. Since the OCR engine is unable to recognize accurately all real character images, a substring matching method is employed to fix wrongly labeled characters by comparing two strings; one is the string grouped by recognized characters in an ideal document image, and the other is the ordered string of characters which we are considering to train and recognize. Based on our method, we build a system that automatically generates 2350 most common Korean and 117 alphanumeric characters from new fonts. The ideal document images used in the system are postal envelope images with characters printed in ascending order of their codes. The proposed system achieved a labeling accuracy of 99%. Therefore, we believe that our system is effective in facilitating the generation of numerous character samples to enhance the recognition rate of existing OCR systems for fonts that have never been trained.

• BMB Reports
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• 제41권1호
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• pp.41-47
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• 2008

Fe65 is characterized as an adaptor precursor (APP) through its PID2 element, as well as with the other members of the APP protein family. With the serum- and glucocorticoid-induced kinase 1 (SGK1) substrate specificity information, we found that the putative site of phosphorylation in Fe65 by SGK1 is present on its $Ser^{566}$ residue in $^{560}CRVRFLSFLA^{569}$(X60469). Thus, we demonstrated that Fe65 and the fluorescein-labeled Fe65 peptide $FITC-^{560}CRVRFLSFLA^{569}$ are phosphorylated in vitro by SGK1. Phosphorylation of the $Ser^{566}$ residue was also demonstrated using a $Ser^{566}$ phospho-specific antibody. The phospho Fe65 was found mainly in the nucleus, while Fe65 S556A mutant was localized primarily to the cytoplasm. Therefore, these data suggest that SGK1 phosphorylates the $Ser^{566}$ residue of Fe65 and that this phosphorylation promotes the migration of Fe65 to the nucleus of the cell.

• 한국유기농업학회지
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• 제22권1호
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• pp.167-182
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• 2014

Korean Panax ginseng C. A. Meyer (P. ginseng) is a well-known and one of the most important tonic herbs used in traditional Korean medicine. The pharmacological effects of P. ginseng have been reported by many researchers. Nevertheless, little is known between the mechanism of action and the active compounds. In this study, we performed a comprehensive proteomic analysis and protein categorization in order to understand the physiological characteristics of the major components in the adventitious roots of P. ginseng. Whole proteins extracted from the cultured adventitious roots of P. ginseng were separated by two-dimensional polyacrylamide gel electrophoresis (2-DE). Among the 1000 spots which were detected by silver staining, 113 spots were labeled and identified by matrix-assisted laser desorption/ionization-time of flight-mass spectrometry (MALDI-TOF MS). Our results showed that 40 proteins were identified among the 113 spots, with a hit ratio of 35.3%. A number of proteins identified on the 2-DE gels (30%; 16 spots) were involved in energy metabolism. These proteomic data will be helpful to better understand the physiological and pharmacological effects of P. ginseng.

• 건축역사연구
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• 제17권4호
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• pp.43-64
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• 2008

Kyeongbokgung succeeded in regaining its status as a royal palace after the reconstruction that began in the second year of King Gojong(1865) only to have most of its buildings taken down in the early 20th century. Fortunately, however, there is the Pukkwoldohyong(Map of North Palace), which drew out each of the buildings of Kyeongbokgung and their arrangement in details in 1907 when the royal palace lost its original appearance. And there is another plot plan of the royal palace at the Korea University Museum, which labeled it Kyeongbokgung-Baechido(Planning Map of Kyeongbokgung Palace). The map presents almost the same plan as Pukkwoldohyong in terms of making and expressive methods, being estimated to have been made in 1888 since its building arrangement doesn't show the changes made after 1890. The map also offers more information about the uses of each building than Pukkwoldohyong and matches the excavation results of the relics. Kyeongbokgung-Jeondo(Map of Kyeongbokgung Palace), which is recorded to be made during the reconstruction of the palace in the early years of King Gojong in historical materials, describes the shapes and arrangements of the buildings in a concrete and realistic fashion. The Kyeongbokgung-Baechido seems to be one of the plans made in the process of restoring and repairing buildings that were lost or destroyed in fire. The Kyeongbokgung-Baschido has the following historic values; 1) it provides dues to estimate the early state of the palace after the reconstruction during the reign of King Gojong. In fact the Sujeongjeon and Heungbokjeon show the early state of the reconstruction; 2) it contains data with which to understand the changes to the palace after 1890, around which they added Hamhwadang and Jibokjae; and 3) it offers information about the uses of the palace's buildings from 1885 to 1880 with its descriptions of the building purposes and relationships regarding the life in the palace.