• Title/Summary/Keyword: Label-Free

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Derivational approach and representational approach in generative grammar (생성문법에서 도출적 접근과 표시적 접근)

  • Choe, Sook-Hee
    • English Language & Literature Teaching
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    • v.10 no.1
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    • pp.179-200
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    • 2004
  • The purpose of this study is to investigate the adequacy of derivational approach and representational approach to syntactic theories in generative grammar. As the generative grammar is based on the derivational process of syntactic theories, it is suggested that derivational approach is more valid than representational approach. Move, Economy Principle, Local Economy and Label-free Phrase Structure in Minimalist framework support the preference of derivational approach to representational approach with the elimination of computational complexity, minimality, and label-free phrase structure. Syntactic structure is considered as the result of the interaction of the properties of lexical items containing probe and economy conditions constrained by bare output conditions. On the other hand, Pseudogapping in Lasnik(1999) is analyzed in terms of Object Shift, that is, overt raising to Spec of $Agr_o$ and the PF deletion of VP in representational approach. Hence, it is suggested that the combination of derivational and representational approaches to syntactic theories can be admitted in generative grammar.

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Multi-Label Classification Approach to Location Prediction

  • Lee, Min Sung
    • Journal of the Korea Society of Computer and Information
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    • v.22 no.10
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    • pp.121-128
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    • 2017
  • In this paper, we propose a multi-label classification method in which multi-label classification estimation techniques are applied to resolving location prediction problem. Most of previous studies related to location prediction have focused on the use of single-label classification by using contextual information such as user's movement paths, demographic information, etc. However, in this paper, we focused on the case where users are free to visit multiple locations, forcing decision-makers to use multi-labeled dataset. By using 2373 contextual dataset which was compiled from college students, we have obtained the best results with classifiers such as bagging, random subspace, and decision tree with the multi-label classification estimation methods like binary relevance(BR), binary pairwise classification (PW).

Efficient Label Placement using Overlap-free Region and Background Analysis (중첩 자유 영역과 배경 분석을 이용한 효율적인 라벨 배치)

  • Lee, San-Won;Jeong, Seung-Do;Choi, Byung-Uk
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.43 no.6 s.312
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    • pp.85-96
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    • 2006
  • This paper deal with a method for efficient placing 2 dimensional virtual labels on the view plane. The proposed method has suitable computational costs for realtime processing and it overcomes the local minima problem which is not solved in previous automatic label placement algorithms, and also it enhances readability by placing labels in less congestion area on the view plane. Background analysis must be considered for label placement. However previous works do not concern with this problem seriously. And furthermore, automatic label placement algorithm and background analysis algorithm have been studied separately in their own field. This paper proposed the background analysis method using background color and texture component to enhance readability, and it is the first research about analyzing the background of color image and applying it in automatic label placement field. This paper shown improved placement performance through combining automatic label placement algorithm and background analysis algorithm organically, and various experiments verified it.

Comparative Review on the Pantyhose Labels according to Producing Countries (팬티스타킹 품질표시에 대한 국가별 비교)

  • 최종명;권수애
    • Journal of the Korean Home Economics Association
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    • v.41 no.3
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    • pp.45-56
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    • 2003
  • The purpose of this study was to compare the pantyhose labels of domestic products which contain fiber content, size spec., care symbol, performance properties with those of foreign-made ones, in order to propose a desirable model of label description for the domestic products. The results were as follows: 1) There were differences in the fiber content and fiber mixture ratio of pantyhose on the label according to the countries. The pantyhoses made in Korea and Japan were described only fiber name on the label, while the pantyhoses made in U.S.A., Taiwan, and England were described fiber name and percent of fiber mixture ratio in detail on the label. 2) Most of the pantyhose size produced and sold in Korea were same Free size, but the products from other countries (U.S.A., England, Japan, Taiwan) were sold in various sizes. 3) There were differences, according to the countries, in the care symbol and related explanation of pantyhose on the label. The pantyhoses made in Korea and Taiwan were described care symbol only on the label, while the pantyhoses made in other countries were described additional explanation for care as well as care symbol on the label. 4) It was known that, unlike Korea, other countries were developing and marketing various types of functional pantyhose. For example, U.S.A. and England were focusing on appearance and comfort aspects of pantyhose, while Japan and Taiwan were focusing to develop functional pantyhose like anti-bacterial and anti-ultraviolet ray pantyhose.

Label-free Femtomolar Detection of Cancer Biomarker by Reduced Graphene Oxide Field-effect Transistor

  • Kim, Duck-Jin;Sohn, Il-Yung;Jung, Jin-Heak;Yoon, Ok-Ja;Lee, N.E.;Park, Joon-Shik
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.02a
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    • pp.549-549
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    • 2012
  • Early detection of cancer biomarkers in the blood is of vital importance for reducing the mortality and morbidity in a number of cancers. From this point of view, immunosensors based on nanowire (NW) and carbon nanotube (CNT) field-effect transistors (FETs) that allow the ultra-sensitive, highly specific, and label-free electrical detection of biomarkers received much attention. Nevertheless 1D nano-FET biosensors showed high performance, several challenges remain to be resolved for the uncomplicated, reproducible, low-cost and high-throughput nanofabrication. Recently, two-dimensional (2D) graphene and reduced GO (RGO) nanosheets or films find widespread applications such as clean energy storage and conversion devices, optical detector, field-effect transistors, electromechanical resonators, and chemical & biological sensors. In particular, the graphene- and RGO-FETs devices are very promising for sensing applications because of advantages including large detection area, low noise level in solution, ease of fabrication, and the high sensitivity to ions and biomolecules comparable to 1D nano-FETs. Even though a limited number of biosensor applications including chemical vapor deposition (CVD) grown graphene film for DNA detection, single-layer graphene for protein detection and single-layer graphene or solution-processed RGO film for cell monitoring have been reported, development of facile fabrication methods and full understanding of sensing mechanism are still lacking. Furthermore, there have been no reports on demonstration of ultrasensitive electrical detection of a cancer biomarker using the graphene- or RGO-FET. Here we describe scalable and facile fabrication of reduced graphene oxide FET (RGO-FET) with the capability of label-free, ultrasensitive electrical detection of a cancer biomarker, prostate specific antigen/${\alpha}$ 1-antichymotrypsin (PSA-ACT) complex, in which the ultrathin RGO channel was formed by a uniform self-assembly of two-dimensional RGO nanosheets, and also we will discuss about the immunosensing mechanism.

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Label-Free Quantitative Proteomics and N-terminal Analysis of Human Metastatic Lung Cancer Cells

  • Min, Hophil;Han, Dohyun;Kim, Yikwon;Cho, Jee Yeon;Jin, Jonghwa;Kim, Youngsoo
    • Molecules and Cells
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    • v.37 no.6
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    • pp.457-466
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    • 2014
  • Proteomic analysis is helpful in identifying cancerassociated proteins that are differentially expressed and fragmented that can be annotated as dysregulated networks and pathways during metastasis. To examine metastatic process in lung cancer, we performed a proteomics study by label-free quantitative analysis and N-terminal analysis in 2 human non-small-cell lung cancer cell lines with disparate metastatic potentials - NCI-H1703 (primary cell, stage I) and NCI-H1755 (metastatic cell, stage IV). We identified 2130 proteins, 1355 of which were common to both cell lines. In the label-free quantitative analysis, we used the NSAF normalization method, resulting in 242 differential expressed proteins. For the N-terminal proteome analysis, 325 N-terminal peptides, including 45 novel fragments, were identified in the 2 cell lines. Based on two proteomic analysis, 11 quantitatively expressed proteins and 8 N-terminal peptides were enriched for the focal adhesion pathway. Most proteins from the quantitative analysis were upregulated in metastatic cancer cells, whereas novel fragment of CRKL was detected only in primary cancer cells. This study increases our understanding of the NSCLC metastasis proteome.

On Minimalist Requirements in Syntax

  • Lee, Hong-Bae
    • Korean Journal of English Language and Linguistics
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    • v.3 no.2
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    • pp.255-280
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    • 2003
  • The present paper will argue what can be considered to be principled elements of the initial state S/sub 0/ of the Faculty of Language, which are called the Interface Condition (IC), and how far we can take the strongest minimalist thesis (SMT), which aims to offer principled explanation of language in terms of IC and the principle of efficient computation, to linguistic analysis. We will discuss implications of label-free phrase structures, required by the strong version of the Inclusiveness Condition, and possibilities of crash-free syntax, required by the condition of efficient computation. I will point out problems of Chomsky's assumption that an externally Merged expletive there is a head, which, as a probe, undergoes agreement with the goal T. I will present several advantages we obtain if we maintain A and A' distinction, and assume that wh-movement to the outer [SPEC, υ] is an A'-movement like wh-movement to [SPEC, C].

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Label-Free Real-Time Monitoring of Reactions Between Internalin A and Its Antibody by an Oblique-Incidence Reflectivity-Difference Method

  • Wang, Xu;Malovichko, Galina;Mendonça, Marcelo;Conceição, Fabricio Rochedo;Aleixo, José AG;Zhu, Xiangdong
    • Journal of the Optical Society of Korea
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    • v.20 no.1
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    • pp.165-168
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    • 2016
  • Surface protein internalin (InlA) is a major virulence factor of the food-borne pathogen L. monocytogenes. It plays an important role in bacteria crossing the host's barrier by specific interaction with the cell adhesion molecule E-cadherin. Study of this protein will help to find better ways to prevent listeriosis. In this study, a monoclonal antibody against InlA was used to detect InlA. The reaction was label-free and monitored in real time with an oblique-incidence reflectivity-difference (OI-RD) technique. The kinetic constants kon and koff and the equilibrium dissociation constant Kd for this reaction were also obtained. These parameters indicate that the antibody is capable of detecting InlA. Additionally, the results also demonstrate the feasibility of using OI-RD for proteomics research and bacteria detection.

SNP Detection Using Indicator-free DNA Chip (비수식화 DNA를 이용한 유전자 검출)

  • Choi, Yong-Sung;Moon, Jong-Dae;Lee, Kyung-Sup
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.06a
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    • pp.410-411
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    • 2006
  • High throughput analysis using a DNA chip microarray is powerful tool in the post genome era. Less labor-intensive and lower cost-performance is required. Thus, this paper aims to develop the multi-channel type label-free DNA chip and detect SNP (Single nucleotide polymorphisms). At first, we fabricated a high integrated type DNA chip array by lithography technology. Various probe DNAs were immobilized on the microelectrode array. We succeeded to discriminate of DNA hybridization between target DNA and mismatched DNA on microarray after immobilization of a various probe DNA and hybridization of label-free target DNA on. the electrodes simultaneously. This method is based on redox of an electrochemical ligand.

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