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Clinical Study of Scalp Acupuncture Effects on Patients with Broca Aphasia (두침요법을 이용한 브로카 실어증 치험례)

  • Park, Sae-Wook;Lee, Min-Goo;Lee, Seung-Eon;Kim, Yong-Jeong;Ryu, Hyun-Hee;Lee, Yun-Jae;Rhim, Eun-Kyung;Lee, Ju-Hee;Kim, Hyun-Gi;Lee, In;Moon, Byung-Soon;Yun, Jong-Min
    • The Journal of Internal Korean Medicine
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    • v.25 no.4
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    • pp.167-176
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    • 2004
  • Objectives : This study was designed to report the clinical effects of scalp acupuncture on patients who suffered from broca aphasia caused by cerebral hemorrhage, Methods : Scalp acupuncture therapy was applied on the above patients for several weeks, For the evaluation of improvement, language field was monitored by aphasia test(RISS) and speech field was monitored by phonetic analysis in the computerized speech lab. Results : According to the above evaluation items, the treatment was beneficial. The score of most items rose in the language field. And scalp acupuncture affected VOT, TD and articular error patterns positively in the speech field. Conclusions : The above results suggest that scalp acupuncture has good effects on the patients with broca aphasia caused by cerebral hemorrhage.

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The Effect of in vitro Hemolysis on Vitamin $B_{12}$ / Folic Acid Results (용혈이 Vitamin $B_{12}$ / Folic acid 검사 결과에 미치는 영향)

  • Kim, Mi-Sook;Cho, Youn-Kyo;Im, Do-Hw;Seo, So-Yeon
    • The Korean Journal of Nuclear Medicine Technology
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    • v.12 no.1
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    • pp.62-65
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    • 2008
  • Purpose: Vitamin $B_{12}$ and folic acid are type of water-soluble vitamin and those work as a secondary vital enzyme, but especially those are involved in the nuclear DNA synthesis. Those are mainly measured in order to diagnose megaloblastic anemia and to assess the storage of folic acid during pregnancy. It is generally known that the hemolyzed serum is useless for folic acid and vitamin $B_{12}$, but it is not easy to abide by this information because our lab (Samkwang Medical Laboratories) is reference laboratory. We tested how much the extent of hemolyzed serum had influence on the results. Materials and Method: We performed the tests of vitamin $B_{12}$, folic acid. For the hemolysis effect study, we used 40 cases. According to the level of A, B and C groups, each group had 10 samples which were mechanically hemolyzed serum. Results: Hemolysis did not affect the vitamin $B_{12}$ results. However in case of folic acid, the value increased according to the degree of hemolysis. And severe hemolyzed cases had the highest value (greater than 20 ng/ml). Conclusions: Preventing the hemolysis, it has to be informed that blood-collecting, separation and storage are performed more carefully. As you see from the above results, hemolyzed serum is not proper for folic acid test, and hemolysis does not affect the results of vitamin $B_{12}$. However, for the more accurate results, it is necessary to avoid hemolysis.

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Isolation of Microorganisms and Development of Microbial Augmentation for Treatment of Industrial Wastewater containing Ammonium Nitrogen (암모니아성 질소함유 산업폐수처리를 위한 미생물의 분리 및 복합미생물제제의 개발)

  • Lee, Myoung-Eun;Mun, Seo-Jin;Kwon, Do-Hyuck;Suh, Hyun-Hyo
    • Journal of Life Science
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    • v.30 no.2
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    • pp.129-136
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    • 2020
  • For effective treatment of wastewater containing ammonium nitrogen (NH4-N), AT2, AT9, and AT12 strains, having high total organic carbon (TOC) removal capability, and FN47, possessing excellent ammonia nitrogen removal capability present in the activated sludge in the aeration tank of food wastewater treatment plants, were isolated and identified. The cells of these isolated strains were used for microbial augmentation with FIW-1 in the defatted rice bran as a medium to treat industrial wastewater. The investigation of the cultural characteristics of these isolated strains in the aeration tank showed that the affinities for substrate of the isolated strains were extremely high, of which AT12 (Alcaligenes sp. AT12) was the highest among the isolated strains. Ammonium nitrogen removal efficiency in the food wastewater was 71% in the isolated strain FN47 (Microbacterium sp. FN47) treatment group. When only activated sludge was added in the lab scale pilot using food wastewater during continuous culture experiment, the TOC removal efficiency was 63%. Meanwhile, the removal efficiency of 92% was obtained when the microbial augmentation FIW-1 for wastewater treatment was applied. In addition, the chemical oxygen demand (COD) level from the effluent wherein microbial augmentation FIW-1 was input for the initial three days in the wastewater treatment site experiment showed a treatment rate of about 43%, which was increased to 62% after an elapse of 5 days.

Effects of the Nuegra from Male Silkworm Extract on Enhancement of the Masculine Function and Activation of Overall Physical Function

  • Kim, D. C.;Kim, Y. W.;Park, M. S.;J. K. Suh;Lee, D. S.;Lee, S. H.;B. H. Chun;Y. K. Jun
    • International Journal of Industrial Entomology and Biomaterials
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    • v.5 no.1
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    • pp.109-122
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    • 2002
  • The purpose of this investigation is to evaluate the effects of the Nuegra on enhancement of the masculine and physical activities in general through measuring changes of the testosterone, FSH and subjective symptoms like fatigue, insomnia, urinary stream, muscular weakness, libido and erectile dysfunction. Total 168 male subjects were enrolled from 12 urology, internal medicine clinics and general practitioner, During the 6-week investigational period, 2 capsules of Nuegra were given to the subjects right after meal for 4 weeks, and 1 capsule of Nuegra was added each time in subjects with no or minimal effect. Testoster-one and FSH levels were measured at first visit and last visit, for evaluating masculine activities. To avoid bias and standardize the test results, only one clinic was assigned as a central lab, and all blood samples were transferred. General information and subjective symptoms were evaluated at first visit and at 2 weeks interval, week 2, 4 and 6 using VAS (Visual Analogue Scale). The mean age of the subjects were 51.8${\pm}$8.2 years old (range: 36.1-82.1). Based on the subjects who were tested on testosterone and FSH levels at day l and week 6, the means were 4.4${\pm}$1.4 nmol/L (range: 2.6-7.7), 8.6${\pm}$9.6 mIU/mL (range: 0.3-40.4), respectively at day 1. At week 6, the results were 4.9 ${\pm}$1.6 (2.6-8.9 range), 9.4${\pm}$13.1 (1.0-53.9 range), respectively. Marginally significant difference between pre-dose and post-dose was present. Statistically significant differences were revealed in general assessment for subjective symptoms, fatigue, insomnia, erectile dysfunction, etc. In fatigue, response rates were 39.6, 65.4 and 76.4% at week 2, 4 and 6, respectively (P < 0.0001). Response vates for erectile dysfunction were 13.4, 41.2 and 72.7% at week 2, 4, and 6 (P < 0.0001), respectively, Response rates for libido were 13.6, 51.6 and 73.5% at week 2, 4, and 6 (P < 0.0001), respectively. For urinary stream response rates were 26.9, 44.7 and 66.8% at week 2, 4, and 6 (P < 0.0001), respectively. VAS for muscular weakness did not show significant results that response rates were 40, 60 and 80% at week 2, 4, and 6 from 8.2 (P = 0.24), respectively. Response rates for insomnia were 50, 60, 100% at week 2, 4, and 6 (P < 0.0001), respectively. The results shows that Nuegra tends to enhance masculine activities including libido, erectile dysfunction and urinary stream and also effective for improving general conditions especially insomnia, muscular weakness and fatigue. In conclusion, this investigation has demonstrated that Nuegra does not only have tendency to increase masculine activities through increased secretion of the testosterone and FSH but also improve general conditions such as erectile dysfunction, libido, fatigue and muscular power.

Electrical and Fluidic Characterization of Microelectrofluidic Bench Fabricated Using UV-curable Polymer (UV경화성 폴리머를 이용한 미소유체 통합접속 벤치 개발 및 전기/유체적 특성평가)

  • Youn, Se-Chan;Jin, Young-Hyun;Cho, Young-Ho
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.36 no.5
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    • pp.475-479
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    • 2012
  • We present a novel polymer fabrication process involving direct UV patterning of a hyperbranched polymer, AEO3000. Compared to PDMS, which is the most widely used polymer in bioMEMS devices, the present polymer has advantages with regard to electrode integration and fast fabrication. We designed a four-chip microelectrofluidic bench having three electrical pads and two fluidic I/O ports. We integrated a microfluidic mixer and a cell separator on the bench to characterize the interconnection performance and sample manipulation. Electrical and fluidic characterization of the microfluidic bench was performed. The measured electrical contact resistance was $0.75{\pm}0.44{\Omega}$, which is small enough for electrical applications, and the pressure drop was 8.3 kPa, which was 39.3% of the value in the tubing method. By performing yeast mixing and a separation test in the integrated module on the bench, we successfully showed that the interconnected chips could be used for bio-sample manipulation.

Characterization of Extended-Spectrum $\beta$-Lactamases (ESBL) Producing Klebsiella and Enterobacter Isolated from Sewerage Plant Drain Water at Kwang-An in Pusan (광안리 오수처리장에 분리된 Extended-Spectrum $\beta$-Lactamase (ESBL) Klebsiella와 Enterobacter의 유형)

  • 이훈구
    • Korean Journal of Microbiology
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    • v.37 no.4
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    • pp.277-283
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    • 2001
  • The emergence of extended spectrum beta-lactamase(ESBL) producing bacteria is causing very serious problems in Korea. Although there have been many reports about these bacteria isolated from patients and clinical specimens, there is no report of ESBL-producing organisms isolated from natural evironment in Korea. This is the first study on the ESBL producing bacteria out of the medical system in Korea. Twenty-six ESBL producing bacteria were isolated only from sewerage plant drain water at Kwang-an beach among the sampling collected sites including snakehead fish plants in Myungi, Aquaculture Engineering Lab. in Pukyong National University and two public-bathrooms in Pusan, Korea. ESBL producing bacteria were identified by double-disk synergy test, conjugation, isoelectric focusing values and PCR. The species of ESBL producing bacteria were Enterobacter cloacae(4 strains), E. sakazakii(8 strains), Klebsiella pneumoniae subsp. pneumoniae(8 strains) and K. pneumoniae subsp. ozaenae(6 strains). TEM and SHV specific PCR products were detected from all the ESBL strains produced TEM+SHV products on the PCR plates. The pI values of ESBL produced by Klebsiella pneumoniae subsp. pneumoniae, K. pneumoniae subsp. ozaenae, Enterobacter cloacae, and E. sakazakii were 5.9, 5.9+5.4; 5.9, $5.9+5.4;{\ge}8.5$, 8.0+5.4, and 8.0+5.4, respectively on the IEF. Seven strains of the isolates were transfered their genes to E. coli RG488 $Rif^r$ by conjugation.

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Effects of High Temperature Deformation and Thermal Exposure on Carbide Reaction Cast Alloy 738LC (고원변형과 열간노출에 따른 주조용 합금 738LC의 탄화물 분해거동 고찰)

  • Ju, Dong-Won;Jo, Chang-Yong;Kim, Du-Hyeon;Seo, Seong-Mun;Lee, Yeong-Chan
    • Korean Journal of Materials Research
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    • v.10 no.2
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    • pp.111-116
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    • 2000
  • Fracture mode and carbide reactions of cast alloy 738LC during thermal exposure and creep at 816$^{\circ}C$/440MPa and 982$^{\circ}C$/152MPa were investigated. Crystallographic transgranular failure was observed in the specimen crept at 816$^{\circ}C$ due to shearing on the slip plane. Because selective oxidation at the grainboundaries which was exposed at the surface leads reduction in surface energy, however, early initiation of crack at the grainboundaries and intergranular failure were observed in the specimen crept at 982$^{\circ}C$/152MPa. As a result of decomposition of MC carbide at the tested temperatures, M(sub)23C(sub)6 carbide precipitated either on the grainboundaries or on the deformation band. The applied stress enhanced decomposition of MC. $\sigma$phase nucleated from Cr(sub)23C(sub)6 then grew to the ${\gamma}$+${\gamma}$\\` matrix. Precipitation of $\sigma$was accelerated by increasing temperature and applied stress.

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The Effect of Invasive Cricket Species, Gryllus bimaculatus on the Survival of Korean Cricket Species, Teleogryllus emma (외래종 쌍별귀뚜라미(Gryllus bimaculatus)가 토착종 왕귀뚜라미(Teleogryllus emma)의 생존율에 미치는 영향)

  • Lee, Eunaa;Kwon, Ohseok
    • Korean Journal of Ecology and Environment
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    • v.46 no.1
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    • pp.67-74
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    • 2013
  • This research was conducted to investigate the competition for survival between the two cricket species: Gryllus bimaculatus (GB) and Teleogryllus emma (TE). The test insects for this research were bred in the greenhouse of the Ecological Entomology Lab, College of Agriculture and Biosciences, Kyungpook National University, Korea. The feeding environment was $28^{\circ}C$ to $30^{\circ}C$, Long-Day condition (16L : 8D) and Relative Humidity: 50%~60%. The changes of the individual number in two species (TE, GB) were checked every day. This research had three experimental conditions which the ratios of individuals (TE : GB) were set at 1 : 2, 1 : 1 and 2 : 1. The survival rate of GB was net better than that of TE in the result of this study. However, due to the absence of the diapauses period in the egg stage, GB would dominate over TE in the field condition. The appropriate legal measure against GB is recommended.

Inactivation of a Norovirus Surrogate (Feline Calicivirus) during the Ripening of Oyster Kimch (굴김치 숙성에 따른 노로바이러스 대체 모델 Feline Calicivirus의 불활성화)

  • Shin, Soon-Bum;Oh, Eun-Gyoung;Yu, Hong-Sik;Lee, Hee-Jung;Kim, Ji-Hoe;Park, Kun-Ba-Wui;Kwon, Ji-Young;Yun, Ho-Dong;Son, Kwang-Tae
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.43 no.5
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    • pp.415-420
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    • 2010
  • In Korea, oysters are used as an ingredient of Kimchi (Korean pickled cabbage) in early winter. Although viral contamination of oysters, including contamination by norovirus, can provoke gastroenteric illness, little is known of the epidemiological relationship to outbreaks. We postulated that Kimchi ripening can reduce the infectivity of norovirus, in order to test this hypothesis, we carried out a model experiment. Since norovirus is currently regarded as non-culturable, feline calicivirus (FCV) was used as a surrogate to examine the activation of norovirus with Kimchi ripening. In commercial well-prepared Kimchi, the infectivity ($TCID_{50}$) of FCV decreased by 2 log every 12 hours and reached the limit of detection after 48 hours during over-aging at $25^{\circ}C$. During storage at $4^{\circ}C$, the infectivity ($TCID_{50}$) of FCV decreased slowly and reached 5.00 $TCID_{50}$ after 48 hours. The low pH appears to affect the infectivity of FCV directly via organic acids produced by ripening during over-aging and storage. In neutralized lab-prepared Kimchi (pH 7.0), the infectivity ($TCID_{50}$) of FCV also decreased and reached the limit of detection after 72 hours at $4^{\circ}C$. This indicates that there are substances beside organic acids in Kimchi that originate from the raw materials and are produced during ripening. Among the raw materials, salt-fermented anchovies and garlic showed high direct antiviral activity. The main factor decreasing the infectivity of FCV in Kimchi was the high acidity caused by organic acids, regardless of the type, produced by ripening. Furthermore, unknown secondary products of microorganisms associated with Kimchi ripening and antiviral materials originating from raw material might contribute to the decreased infectivity of FCV, the surrogate of norovirus.

2-D Axisymmetric Non-linear Finite Strain Consolidation Model Considering Self-weight Consolidation of Dredged Soil (준설매립지반의 자중압밀을 고려한 2차원 축대칭 비선형 유한변형 압밀 모델)

  • Kwak, Tae-Hoon;Lee, Dong-Seop;Lim, Jee-Hee;Stark, T.D.;Choi, Eun-Seok;Choi, Hang-Seok
    • Journal of the Korean Geotechnical Society
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    • v.28 no.8
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    • pp.5-19
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    • 2012
  • Vertical drains along with the preloading technique have been commonly used to enhance the consolidation rate of dredged placement formation. In practice, vertical drains are usually installed in the process of self-weight consolidation of a dredged soil deposit because this process takes considerable time to be completed, which makes conventional analytical or numerical models difficult to quantify the consolidation behavior. In this paper, we propose a governing partial differential equation and develop a numerical model for 2-D axisymmetric non-linear finite strain consolidation considering self-weight consolidation to predict the behavior of a vertical drain in the dredged placement foundation which is installed during the self-weight consolidation. In order to verify the developed model in this paper, results of the numerical analysis are compared with that of the lab-scaled self-weight consolidation test. In addition, the model verification has been carried out by comparing with the simplified method. The comparisons show that the developed model can properly simulate the consolidation of the dredged placement formation with the vertical drains installed during the self-weight consolidation. Finally, the effect of construction schedule of vertical drains and of pre-loading during the self-weight consolidation is examined by simulating an imaginary dredged material placement site with a thickness of 10 m and 20 m, respectively. This simulation infers the applicability of the proposed method in this research for designing a soil improvement in a soft dredged deposit when vertical drains and pre-loading are implemented before the self-weight consolidation ceases.