• 제목/요약/키워드: LT-60

검색결과 106건 처리시간 0.027초

Inhibitory effects of the medicinal plant extracts on tyrocinase and elastase, and free radical scavenging effects.

  • Kim, Ik-Soo;Kim, Mi-Jung;Lee, Bock-Soon;Na, Hun-U;Jeon, Jong-Taek;Lee, Hee-Bong
    • 대한화장품학회:학술대회논문집
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    • 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
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    • pp.820-829
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    • 2003
  • One of the important function of skin is the protection from harmful environments. Many studies were carried out to keep the skin from wrinkling and pigmenting. Skin wrinkle and pigmentation could be caused' by the unusual disruption of connective tissue, the formation of free radicals and the radiation of ultraviolet. In this study, the extracts obtained from 23 different kinds of medicinal plants were examined whether they have inhibitory effect on tyrosinase and elastase as well as free radical scavenging effect. All the extracts examined were obtained by using 70% (v/v) ethanol at $60^{\circ}C$. It has been found that there were two medicinal plants which have positive effects matching with the purpose of this study. The extract of Ephedra sinica stapf shows an inhibitory effect on tyrosinase ($IC_{50}$ = 83.7~$\mu\textrm{g}$/ml), on elastase ($IC_{50}$ = $690{\mu}\textrm{g}$/ml), and also shows free radical scavenging effect ($IC_{50}$ = 29.6$\mu\textrm{g}$/ml). The extract of Betula platyphylla Var. shows an inhibitory effect on elastase ($IC_{50}$ = 498.1$\mu\textrm{g}$/ml), and free radical scavenging effect ($IC_{50}$ = 9$\mu\textrm{g}$/ ml). The aim of the study is to find the natural compounds which have function in skin-lightening, anti-wrinkling and anti-oxidation, with safe and active ingredients in cosmetic.

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복부 둔상에 의한 얕은엉덩휘돌이동맥 파열의 혈관조영색전술을 통한 성공적인 치료: 증례보고 (Successful Angiographic Embolization of Superficial Circumflex Iliac Artery Rupture Caused by Blunt Abdominal Trauma: A Case Report)

  • 이상봉;박성진;여광희;김호현;박찬용;김재훈;김창완;최선우;김선희;황정주;조현민
    • Journal of Trauma and Injury
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    • 제28권1호
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    • pp.39-42
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    • 2015
  • Lat. abdominal wall hematoma with active bleeding is very rare but need prompt bleeding control. We report successful treatment by angiographic embolization of superficial circumflex iliac artery rupture caused by blunt trauma. A 60-year-old woman presented painful, enlarging, lat. abdominal wall mass with ecchymosis caused by blunt abdominal trauma. Contrast leakage of superficial circumflex iliac a. within the lt. ext. oblique m. hematoma was confirmed by abdominal computed tomography. Angiographic embolization was performed successfully. Patient was discharged at 4th day after trauma without complication. Angiographic embolization is important treatment option of lat. abdominal wall hematoma with active bleeding replacing emergency surgery.

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Establishment of a linear regression equation for quantification of beta-hemolytic Escherichia coli in different media and survival of hemolytic Escherichia coli after blending with three different media

  • Kim, Jae Cheol;Pluske, John R.;Yoo, Jaehong;Heo, Jung Min
    • 농업과학연구
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    • 제41권2호
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    • pp.135-139
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    • 2014
  • Pathogenic E. coli associated post-weaning diarrhea (PWD) and edema disease are common diseases in commercially-housed weanling pigs. An enterotoxigenic E. coli (ETEC) oral challenge model has been used to mimic the physiological responses observed in commercial conditions. However, an oral challenge procedure has two major limitations: (1) the ETEC cell density is unknown at the point of oral inoculation, and (2) blending ETEC with traditional TSB (trypticase soy broth) is not palatable and hence decreases acceptability by piglets. Therefore, the purposes of this study were to (1) establish a regression equation that can be used for estimation of ETEC concentration in dilution media using the spectrophotometric measurement of cell density; and (2) examine survival of ETEC after blending either with TSB, sweetener or dextrose. A strain of ETEC (serogroup beta-hemolytic E. coli O149; K91; F4; toxins LT, STa, STb) was grown in TSB for 3.5 hours, centrifuged, the supernatant was discarded, and the ETEC pellet was then blended either with TSB (100 mL), sweetener (60 mL TSB + 40 mL fruit flavored concentrate), or dextrose (50 mL TSB + 50 mL dextrose; 0.5g/mL dextrose). Cell density was measured using the colorimetric method and also plated on a 5% sheep blood agar for counting of ETEC colony forming units at 0, 5, 35, 65 and 125 min after blending. The optical density at 600 nm explained 83% of ETEC colony forming units, indicating that the established linear equation (y= 6E+08x - 4E+07, P<0.004) can be used for robust quantification of ETEC cell density in TSB, sweetener and dextrose media. When ETEC was blended with sweetener and dextrose, survival of ETEC was decreased by 45% and 72% within 5 min post-blending. Therefore, further research is required to find out the suitable medium that has potential to improve palatability without compromising survival of ETEC.

Variations in Stroke Patients' Muscle Activity during Head Rotation in Non-Paretic-Side Weight Bearing

  • Lee, Kwan-Sub;Choe, Han-Seong;Lee, Byung-Joo
    • The Journal of Korean Physical Therapy
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    • 제27권3호
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    • pp.159-163
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    • 2015
  • Purpose: This study aimed to determine the interaction among the neck, trunk, and lower extremities on the non-paretic side in head rotation along with non-paretic-side weight shifting of stroke patients. To compare stroke patients' ability to control posture through muscle activity variation related to pertubation during head rotation along with the non-paretic limb. Methods: We tested 15 hemiplegic patients and 15 normal individuals. Each group's muscle activity was measured by electromyography in neutral head position and head rotation position. We compared each group's resu lt based on measured values in patients' non-paretic neck muscles, trunk muscles, and lower limbs muscles activation. Results: The study showed that muscle activity increased in the sternocleidomastoid muscle (102.26%, 53.00%), splenius capitis muscle (97.93%, 54.93%), erector spinae muscle (241.00%, 127.60%), external oblique abdominal muscle (256.66%, 152.00%), and internal oblique abdominal muscle (252.80%, 152.6%), peroneus longus muscle (117.53%, 137.13%) and gastrocnemius muscle (119.06%, 137.20%), while the results for the sternocleidomastoid muscle, splenius capitis muscle, erector spinae muscle, external oblique abdominal muscle, internal oblique abdominal muscle, peroneus longus muscle, and gastrocnemius muscle showed a statistically significant difference (p<0.05). Conclusion: It is hard for stroke patients to engage in normal movement control under suggested conditions because of the insufficient movement against gravity on the stroke patient's non-paretic side and impaired cooperative patterns. To solve these problems, patients need their bodies to improve through effective movement, resulting in advanced control of their effective and functional activity.

허약노인을 위한 건강증진 프로그램이 허약노인의 건강증진행위와 건강상태에 미치는 효과 (The Effect of Health Promotion Program for Frail Elderly Residents on Health Promoting Behavior and Health Status)

  • 권상민;박정숙
    • 성인간호학회지
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    • 제25권2호
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    • pp.194-206
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    • 2013
  • Purpose: The purpose of this study was to develop a health promotion program for frail elderly nursing home residents, and to analyze the effects of the program. Methods: The research was a nonequivalent control group pretest-posttest design. Data collection was performed from February 26, 2012, to April 26, 2012. The subjects were 28 residents for the experimental group, who were selected at A nursing home, D city, in Korea and 27 residents for the control group, who were selected at B nursing home. Data were analyzed using descriptive statistics, ${\chi}^2$-test, independent t-test, ANCOVA and Cronbach's ${\alpha}$ with SPSS/Win 17.0 program. Results: There was a significant improvement in health promoting behaviors (F=64.26, p<.001), Lt. Grip strength (F=39.76, p<.001), Rt. Grip strength (F=38.06, p<.001), Static balance (F=3.98, p=.050), TUG (F=18.60, p<.001), oral status (F=26.75, p<.001), depression (F=18.79, p<.001), and subjective health status (F=10.75, p<.002) in the treatment group compared to the comparison group. Conclusion: The health promotion program improved the health promoting behavior, physical fitness, oral status, depression, and subjective health status of the frail elderly nursing home residents. Therefore, health promotion programs for frail elderly nursing home residents could be helpful.

신체의 부위별 피복이 체온조절 및 주관적인 감각에 미치는 영향(II) (Effects of Covering Parts of Body with Garments on Human Thermoregulation and Sensation(II))

  • 이종민
    • 한국의류학회지
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    • 제18권3호
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    • pp.339-347
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    • 1994
  • In this study the physiological significance of the upper and lower body on thermoregulation and sensation are examined. Experiments were carried out on 4 females in a climatic chamber conditioned at $25\pm1^{circ}C, 50\pm5%$ R.H.. Before the measurements, subjects were exposed to 3 types of enviromental temperature: 1) $25\pm1^{\circ}C$ for 60 min.(ST), 2) $25^{\circ}C$\rightarrow35^{circ}C\rightarrow25^{\circ}C$ for about 40 min.(HT), 3) $25^{\circ}C$\rightarrow15^{circ}C\rightarrow25^{\circ}C$ for about 40 min.(LT) covering the upper body (U) or lower body (L) with garments. 1) $T_{re}$ was significantly higher in L than in U only in 57 condition. $T_{sk}$ and Temp. under the clothing were higher in U than in L in all three conditions. Thermal sensation was warmer in U than in L, and comport sensation was most comfortable in HT condition. 2) When the upper or lower body was covered or exposed, the mean skin temperature of the upper body was higher than that of the lower body. Following covering and uncovering the same area, the changes in skin temperature were greater in the upper body than in lower body, and covering the upper body produced a greater difference of skin temperature between body and lower body than covering the lower body. 3) In all environmental conditions, when the upper body was uncovered, the skin temperatures of the chest, upper arms and forearms dropped to a considerable degree, and when the lower body was uncovered, skin temperatures of the legs showed the same pattern. On the other hand, skin temperature of the thinghs showed only little change in all cases except forehead and back uncovered or covered in two clothing types.

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왕벚나무 꽃잎 추출물에 대한 견직물의 염색성과 색채특성 (Dyeing Properties and Color Characteristics of Silk Fabrics Dyed with Prunus yedoensis Matsumura Flower Extract)

  • 이은주;유은숙;한충훈;이안례
    • 한국염색가공학회지
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    • 제22권3호
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    • pp.194-206
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    • 2010
  • This study was carried out to identify the optimum dyeing conditions for maximum dye uptake of Prunus yedoensis Matsumura flower extract on silk fabric and to investigate hue/tone characteristics and fastness properties of the dyed fabrics. As results, the flower extract was found to contain flavonoids by FT-IR and to show yellowish shade by UV-vis spectrum. Silk fabric was optimized for maximum dye uptake to five repetitions of dyeing at $80^{\circ}C$ for 60 min with an extract concentration of 600% owf in terms of both K/S and color differences. Pre-mordanting was more effective to dye uptake than post-mordanting for all of the mordants used. Un-mordanted and pre-mordanted fabric showed YR(Yellow Red) while most of post-mordanted ones did Y(Yellow). Main tones of dyed fabrics were sf(soft) and lt(light) in the case of unmordanting or Al-mordanting whereas they were d(dull) and g(grayish) by post-mordanting with Cu, Cr, and Fe, respectively. The fastness grades to rub and dry cleaning were reasonably good for most dyeing conditions while those to light were poor. Finally dyeing condition for each hue/tone of the dyed silk with the flower extract was optimized considering fastness properties.

Physical Property and Virtual Sewing Image of Lyocell treated with Epichlorohydrine for the fibrillation control

  • Park, Ji-Yang;Jeon, Dong-Won;Kim, Sin-Hee
    • 패션비즈니스
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    • 제12권6호
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    • pp.46-60
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    • 2008
  • Lyocell is a regenerated cellulosic fiber manufactured by an environmentally friendly process. The major advantages of lyocell are the excellent drape forming property, the genuine bulkiness, smooth surface, and high dry/wet tenacities. However, one drawback of lyocell is its fibrillation property, which would degrade its aesthetic quality and lower the consumer satisfaction. In our previous studies, lyocell was treated with epichlorohydrin, a non-formalin based crosslinker, to reduce its fibrillation tendency. To investigate the changes of physical properties upon ECH-treatment, the hand characteristics of ECH-treated fabric were observed using KES-FB system and the 3D-virtual sewing image of the fabrics were obtained using 3D CAD simulation system in this study. Since epichlorohydrin(ECH) treatment was conducted in the alkaline medium, the weight reduction was observed in all treated lyocell. The treated lyocell became light, smooth and flexible in spite of ECH crosslinker application. LT and RT in tensile property upon the ECH treatment did not change significantly, however, EMT and WT in the tensile property increased. The significant decrease in bending rigidity was resulted in all ECH-treated lyocell, which is the result of the weight loss upon the alkali condition of ECH treatment. The bending rigidity increased again in the ECH 30% treated lyocell, however, the B value is still lower than the original. Therefore, the ECH-treated lyocell would be more stretchable and softer than the original. Shear rigidity was also decreased in all ECH-treated lyocell, which would result in more drape and body fitting when it is made as a garment. The ECH-treated fabric showed the softer smoother surface according to SMD value from KES evaluation. The virtual 3D sewing image of the ECH-treated lyocell did not show a significant change from that of the original except ECH 30% treated lyocell. ECH 30% treated lyocell showed a stiffer and more puckered image than the original.

자외선 차단 가공에 의한 면직물의 역학적 특성 변화 (Effect of UV-Absorber Treatment on the Mechanical Properties of Cotton Fabrics)

  • Kwon, Young-Ah;Kang, Mi-Jung;Cho, Hyun-Hok
    • 한국의류학회지
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    • 제26권12호
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    • pp.1701-1708
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    • 2002
  • 본 연구의 목적은 자외선 차단 가공 처리 및 자외선 조사처리에 의해 면직물의 역학적 특성 변화를 조사하고 가공제 처리조건에 따른 차이점을 분석하는 것이다. 시료로는 100% 면직물을, 자외선 흡수제로 2,2'-dihydroxy-4,4'-dimethoxy benzophenone을, 첨가제로 Triton X-100, polyethylene glycol 400, MgCl$_2$.6$H_2O$를 사용하였다. 자외선 흡수제 처리는 Atlas Launder-O-meter로 75$^{\circ}C$에서 60분간 흡진법으로 하였다. 미처리 시료 및 처리시료는 모두 xenon 램프에 80시간 동안 노출되었으며, 자외선 조사 전후 시료의 역학적 특성은 KES-F시스템을 사용하여 측정하였다. 본 연구의 결과는 다음과 같이 요약할 수 있다. 자외선 흡수제 처리는 처리 농도에 상관없이 면직물의 선형인장성(LT), 인장레질리언스(RT), 굽힘강성(B), 굽힘이력(2HB), 전단강성(G), 전단이력(2HG5), 표면마찰계수(MIU)등을 증가시켰으며 표면거칠기(SMD)는 감소시켰다. 압축특성은 처리농도의 영향을 받아서 고농도의 자외선 흡수제 처리는 압축특성을 감소시켰으며, 저농도의 처리는 압축특성을 증가시켰다. 자외 선 흡수제 처리는 처리농도에 상관없이 면직물의 fullness/softness를 유의하게 증가시키는 반면 stiffness, crispness및 anti-drape stiffness를 감소시켜서 가공포의 종합태(THV)는 가공 전에 비하여 저하하였다. 자외선 조사는 가공 전 면직물의 경우 B, 2HB, G, 2HG, 2HG5, LC를 감소시켰다. 자외선 조사는 처리농도와 상관없이 가공포의 WT, 굽힘특성 , 전단특성을 감소시켰으며, 저농도의 흡수제 처리포의 경우 SMD를 증가시켰으며, 고농도의 흡수제 처리포의 경우 SMD를 감소시켰다. 자외선 조사는 처리농도와 상관없이 가공포의fullness/softness, stiffness, anti-drape stiffness를 유의하게 감소시켜서 자외선 조사 전 보다 THV가 37% 저하하였고 미 가공포의 THV를 저하율보다는 저하가 낮았다. 자외선 흡수제 처리에 의해 면직물의 태는 가공 전보다 감소하지만, 자외선 흡수제 처리는 자외선 조사에 의한 태 감소율을 낮추는 데 유의 한 효과가 있다.

최근 분리된 장내 병원성 대장균의 항균제 감수성 (In Vitro Susceptibility of Diarrhea-Causing Escherichia coli to 9 Antibacterial Agents in Clinical Use)

  • 김재호;김경희;조양자;서인수
    • 대한미생물학회지
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    • 제22권2호
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    • pp.155-162
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    • 1987
  • To determine the prevalence of antibiotic resistance in fecal E. coli and to investigate possible associations between antibiotic resistance and other plasmid-mediated virulence properties, antibiotic disk susceptibility tests for nine antibiotics were done on 141 strains of E. coli isolated from diarrheal children and well controls. Eighty two percent of the test strains were resistant to one or more antibiotics. Antibiotics to which the test strains were most resistant in descending order were ampicillin (85%), trimethoprim/sulfamethoxazol (60%), and cephalothin (55%). Seventy nine percent of these resistant strains were resistant to two or more antibiotics. All 141 test strains were sorted into enterotoxigenic E. coli (ETEC), enteropathogenic E. coli (EPEC), enteroadherent E. coli (EAEC) and non-pathogenic E. coli and the percentages of strains resistant to multiple antibiotics were compared. Among ETEC regardless of its source, multiple drug resistance was more frequent in strains producing heatstable enterotoxin (ST) only than in strains producing only heat-labile enterotoxin (LT) or both. In EAEC, multiple resistance was more frequently associated with strains isolated from diarrheal patients than with those from well controls. The major antibiotic resistance patterns possessed by multiple resistant enteropathogenic strains were $SXT^R$ $AM^R$, $CR^R$, and $SXT^R$ $AM^R$ $CR^R$. Of 28 ST- producing $SXT^R$ ETEC, 26(96%) were also resistant to ampicillin and 17 (61%) were resistant to cephalothin. The similar pattern was observed in EAEC and EPEC as well. This study has important implications for the treatment of E. coli diarrhea with antibiotics because it is possible that dissemination of virulence could occur under the force of selective antibiotic pressure. In addition, this study suggests that the in vivo efficacy of SXT in treating diarrheal illness be reevaluated.

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