• Title/Summary/Keyword: LOCAL TERM

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Multimodal therapy for locally advanced prostate cancer: the roles of radiotherapy, androgen deprivation therapy, and their combination

  • Lee, Sung Uk;Cho, Kwan Ho
    • Radiation Oncology Journal
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    • v.35 no.3
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    • pp.189-197
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    • 2017
  • Locally advanced prostate cancer (LAPC) is defined as histologically proven T3-4 prostatic adenocarcinoma. In this review, we define the individual roles of radiotherapy (RT), short-term (ST-) and long-term (LT-) androgen deprivation therapy (ADT), and their combination in multimodal therapy for LAPC. Despite limitations in comparing the clinical outcomes among published papers, in the present study, a trend of 10-year clinical outcomes was roughly estimated by calculating the average rates weighted by the cohort number. With RT alone, the following rates were estimated: 87% biochemical failure, 34% local failure (LF), 48% distant metastasis (DM), 38% overall survival (OS), and 27% disease-specific mortality (DSM). Those associated with ADT alone were 74% BCF, 54% OS, and 25% DSM, which appeared to be better than those of RT alone. The addition of ADT to RT produced a notable local and systemic effect, regardless of ST- or LT-ADT. The LF rate decreased from 34% with RT alone to 21% with ST-ADT and further to 15% with LT-ADT. The DM and DSM rates also showed a similar trend among RT alone, RT+ST-ADT, and RT+LT-ADT. The combination of RT+LT-ADT resulted in the best long-term clinical outcomes, indicating that both RT and ADT are important parts of multimodal therapy.

Reliability Computation of Neuro-Fuzzy Model Based Short Term Electrical Load Forecasting (뉴로-퍼지 모델 기반 단기 전력 수요 예측시스템의 신뢰도 계산)

  • Shim, Hyun-Jeong;Wang, Bo-Hyeun
    • The Transactions of the Korean Institute of Electrical Engineers A
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    • v.54 no.10
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    • pp.467-474
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    • 2005
  • This paper presents a systematic method to compute a reliability measure for a short term electrical load forecasting system using neuro-fuzzy models. It has been realized that the reliability computation is essential for a load forecasting system to be applied practically. The proposed method employs a local reliability measure in order to exploit the local representation characteristic of the neuro-fuzzy models. It, hence, estimates the reliability of each fuzzy rule learned. The design procedure of the proposed short term load forecasting system is as follows: (1) construct initial structures of neuro-fuzzy models, (2) store them in the initial structure bank, (3) train the neuro-fuzzy model using an appropriate initial structure, and (4) compute load prediction and its reliability. In order to demonstrate the viability of the proposed method, we develop an one hour ahead load forecasting system by using the real load data collected during 1996 and 1997 at KEPCO. Simulation results suggest that the proposed scheme extends the applicability of the load forecasting system with the reliably computed reliability measure.

Effects of Oriental Medical Treatment on ADHD - A retrospective clinical survey - (ADHD에 대한 한방치료의 효과에 대한 후향적 관찰 연구)

  • Byun, Ki-Won;Kim, Joo-Ho;Kim, Jong-Woo;Chung, Sun-Yong
    • The Journal of Korean Medicine
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    • v.32 no.4
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    • pp.75-82
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    • 2011
  • Objectives: This case report aimed to evaluate whether oriental medical treatment was effective on ADHD through a records review of a local oriental medical clinic. Methods: We reviewed clinical charts of a local oriental medical clinic between December 2007 and September 2010 to select ADHD patients. Among those patients, for comparison before and after treatment, we selected cases which had at least twice Stroop test results and 2 months of treatment. Baseline, 3-month and 6-month Stroop test results were compared. Oriental medical treatment consisted of 2 months' herbal medicine, periodic acupuncture and exercise. Results: 1. 3-month data showed that subjects were 12 and improved word score and word-color score of Stroop test. 2. 6-month data showed that subjects were 20 and improved word score, color score, and word-color score of Stroop test. Conclusions: 1. Relatively short term herbal medication and exercise are effective on the word score and word-color score of the Stroop test. 2. After short term herbal medication, continuous exercise maintained the effects of short term oriental medical treatment. 3. We need to consider the balance of left and right as an important point of exercise, but further study is needed.

Determinants of Economic Growth in Indonesia: A Dynamic Panel Model

  • BASUKI, Agus Tri;PURWANINGSIH, Yunastiti;SOESILO, Albertus Maqnus;MULYANTO, Mulyanto
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.11
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    • pp.147-156
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    • 2020
  • This study aims to analyze the effect of public spending, macroeconomic variables, and BPK opinion on economic growth. This study is motivated by the inequality of fiscal policy effectiveness between regions in Indonesia in influencing the economic growth of different regions, the ability of local governments to attract foreign investors, and the transparency of regional financial management in designing development programs to encourage regional economic growth. The analytical tool in this study is a dynamic panel regression model with data from 2008 to 2017. The results of this study show that, in the short term, the population affects regional economic growth, while in the long term, the economic growth is affected by the number of people, the poor, General Allocation Fund, health budget, foreign investment and BPK opinion. The findings of this study are that in the long term the General Allocation Fund becomes an obstacle to economic growth, this is because the general allocation funds is widely used to cover the lack of funds for routine regional activities, thereby reducing activities for development programs. Another research finding is that fiscal policies carried out by local governments make a small and ineffective contribution to promoting economic growth.

A Study on the Development of Export Determinant Model for Laver of Producing District (김 산지 수출량 결정 모형 개발 연구)

  • Choi, Se-Hyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.1
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    • pp.585-590
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    • 2016
  • The objective of this study was to develop an export determinant model for laver in the producing district. The annual and monthly amounts of laver products, local price, export price, and foreign exchange rate were included as explanatory variables. The estimation showed that the laver export is influenced more by the long term rather than short term product increase. In addition, as the foreign exchange rate and export price increase, the quantities exported decrease elastically. On the other hand, as the price in the local market increases, the quantities exported decrease non-elastically. Therefore, to enhance the laver exports, it is important to establish infrastructure for long term production increase, forecast and provide information on the export price and foreign exchange rate more accurately.

Mid- to Long-term Development Strategies of Business Incubation Centers - Based on Interviews with Start-up Companies and Benchmarking of Business Incubation Centers in Developed Countries (창업보육센터의 중장기 발전 전략: 창업기업 인터뷰와 선진국 창업보육센터 벤치마킹을 토대로)

  • Soo Kyung Kim
    • Journal of Information Technology Applications and Management
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    • v.30 no.4
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    • pp.1-9
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    • 2023
  • The purpose of this study was to make a mid- and long-term development plan on the business incubator center after interviewing five startups that currently being occupied in or already left the center and reviewing benchmark on business incubator centers in developed countries such as USA, Sweden, and Israel. For the interview, the three startups currently being occupied in the center and the two companies already left the center were participated. The main strengths of the center from all of these five companies were easy accessibility to the equipment and space and at the same time trustworthy from the outside vendors and/or government, etc. USA is a leading country who has long history for the startups but mostly the private companies/organizations/individuals have supported the startups in terms of funding or consulting. Also, there are countless local governments nationwide who provide funding, education, and/or space for the small businesses. Mainly based on the interview and the benchmarking, the mid- and long-term development plan for the business incubator center was made. All six themes such as consortium for investment or a local network plan were derived for the development plan which was described in this study.

Unstructured discretisation of a non-local transition model for turbomachinery flows

  • Ferrero, Andrea;Larocca, Francesco;Bernaschek, Verena
    • Advances in aircraft and spacecraft science
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    • v.4 no.5
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    • pp.555-571
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    • 2017
  • The description of transitional flows by means of RANS equations is sometimes based on non-local approaches which require the computation of some boundary layer properties. In this work a non-local Laminar Kinetic Energy model is used to predict transitional and separated flows. Usually the non-local term of this model is evaluated along the grid lines of a structured mesh. An alternative approach, which does not rely on grid lines, is introduced in the present work. This new approach allows the use of fully unstructured meshes. Furthermore, it reduces the grid-dependence of the predicted results. The approach is employed to study the transitional flows in the T106c turbine cascade and around a NACA0021 airfoil by means of a discontinuous Galerkin method. The local nature of the discontinuous Galerkin reconstruction is exploited to implement an adaptive algorithm which automatically refines the mesh in the most significant regions.

An Improved Level Set Method to Image Segmentation Based on Saliency

  • Wang, Yan;Xu, Xianfa
    • Journal of Information Processing Systems
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    • v.15 no.1
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    • pp.7-21
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    • 2019
  • In order to improve the edge segmentation effect of the level set image segmentation and avoid the influence of the initial contour on the level set method, a saliency level set image segmentation model based on local Renyi entropy is proposed. Firstly, the saliency map of the original image is extracted by using saliency detection algorithm. And the outline of the saliency map can be used to initialize the level set. Secondly, the local energy and edge energy of the image are obtained by using local Renyi entropy and Canny operator respectively. At the same time, new adaptive weight coefficient and boundary indication function are constructed. Finally, the local binary fitting energy model (LBF) as an external energy term is introduced. In this paper, the contrast experiments are implemented in different image database. The robustness of the proposed model for segmentation of images with intensity inhomogeneity and complicated edges is verified.

Recommendations on the Sustainability and Role of Local Archives (지역 아카이브의 지속가능성과 역할에 관한 제언)

  • Jung, Soahn
    • Journal of Korean Society of Archives and Records Management
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    • v.21 no.3
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    • pp.217-225
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    • 2021
  • This article delves into community archives based on the archival project of Dongjak-gu Public Library on the search toward sustainability. Dongjak-gu has conducted a local archiving project that involves collecting local records, focusing on the role of local public institutions as representative districts in the local region after the library was established in September 2013. Thus far, we are managing the project and records that are piled at the public library, and as the placement for archiving local records conducted in a local public library does not match its role, the national/city/province system for archiving local records faces a challenge for long-term sustainability. Therefore, we would like to present an idea for sustainability by discussing our concerns and experiences in this paper.

A Novel Nipple Reconstruction Technique for Maintaining Nipple Projection: The Boomerang Flap

  • Kim, Young-Eun;Hong, Ki Yong;Minn, Kyung Won;Jin, Ung Sik
    • Archives of Plastic Surgery
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    • v.43 no.5
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    • pp.470-473
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    • 2016
  • Nipple-areolar complex (NAC) reconstruction is the final step in the long journey of breast reconstruction for mastectomy patients. Successful NAC reconstruction depends on the use of appropriate surgical techniques that are simple and reliable. To date, numerous techniques have been used for nipple reconstruction, including contralateral nipple sharing and various local flaps. Recently, it has been common to utilize local flaps. However, the most common nipple reconstruction problem encountered with local flaps is the loss of nipple projection; there can be approximately 50% projection loss in reconstructed nipples over long-term follow-up. Several factors might contribute to nipple projection loss, and we tried to overcome these factors by performing nipple reconstructions using a boomerang flap technique, which is a modified C-V flap that utilizes the previous mastectomy scar to maintain long-term nipple projection.