• 제목/요약/키워드: LN

검색결과 1,261건 처리시간 0.032초

로그-정규분포와 파레토 합성 분포의 임계점 추정 (Threshold estimation for the composite lognormal-GPD models)

  • 김보배;노지숙;백창룡
    • 응용통계연구
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    • 제29권5호
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    • pp.807-822
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    • 2016
  • LN-GPD 합성 분포는 몸통부분은 로그-정규분포를 두터운 꼬리에 대해서는 GPD분포를 따르도록 합성한 분포로 두터운 몸통과 꼬리를 동시에 가지는 자료를 절삭없이 효율적으로 다룰 수 있는 분포이다. 하지만 임계점을 포함하고 있기에 최대우도추정량은 매우 불안정함이 잘 알려져 있어 본 논문이서는 이를 극복하기 위해서 임계점을 먼저 추정하고 나머지 모수들에 대해서 따로 추정하는 2단계 추정 방법들에 대해서 살펴보고 그 성능을 비교해 보았다. 그 결과 동시 추정하는 최대우도추정량의 경우 불안정한 추정이 GPD 분포의 꼬리 지수에서 두드러 졌으며 임계점에 대해서는 비교적 잘 추정함을 알 수 있었다. 이와 반대로 여러 비모수적인 방법들은 꼬리 지수는 만족스럽게 잘 추정하였으나 임계점의 경우 편의가 있음을 관찰할 수 있었다. 실증자료 분석을 위해 2단계 추정법을 이스라엘 은행의 콜센터에서 수집한 서비스 시간에 대한 자료에 적합해 보았으며 그 결과 LN-GPD 합성 분포를 사용하는 것이 로그-정규분포 혹은 GPD 분포 단독으로 사용하는 것보다 자료의 손실도 없이 더 좋은 적합도를 보임을 알 수 있었다.

Pharmacokinetic Behavior and Biodistribution of Paclitaxel-Loaded Lipid Nanosuspension

  • Choi, Sung-Up;Park, Jung-Min;Choi, Woo-Sik;Lee, Jae-Hwi;Choi, Young-Wook
    • Journal of Pharmaceutical Investigation
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    • 제39권5호
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    • pp.359-366
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    • 2009
  • In this study, paclitaxel-loaded lipid nanosuspension (PxLN) was prepared and the in vivo profiles after intravenous administration in rats were investigated. We compared the manufacturing processes depending on the temperature: PxLN-H for a hot homogenization process and PxLN-C for solidification of lipid-drug mixtures by liquid nitrogen. Both formulations showed submicron size distribution and the similar drug loading efficiency of about 70%. In vitro release of PxLNs and Taxol$^{(R)}$ performed by a dialysis diffusion method showed similar pattern for PxLN-H and Taxol$^{(R)}$, but the reduced release profile for PxLN-C. PxLN or Taxol$^{(R)}$ was intravenously administered to the rats at a dose of 5 mg/kg as paclitaxel. The drug in blood samples were assayed by the HPLC/MS/MS method. The AUC$_t$ of PxLN-H was 3.4-fold greater than that of Taxol$^{(R)}$. PxLN-H gave higher biodistribution in all tissues than did Taxol$^{(R)}$. In addition, it maintained the higher drug concentration for 12 h. This lipid nanosuspension might be a promising candidate for an alternative formulation for the parenteral delivery of poorly water-soluble paclitaxel.

액체질소 중 열기포 형상 및 절연 특성 (Shape and Dielectric Strength of Thermal Bubbles in Liquid Nitrogen)

  • 백승명;김해종
    • 한국전기전자재료학회논문지
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    • 제28권5호
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    • pp.326-331
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    • 2015
  • In this paper, we study the insulating properties of the liquid nitrogen(LN2) including the thermal bubbles. The shape of the thermal bubbles in accordance with the current change was observed in the 77 K and 65 K LN2. According to the temperature of liquid nitrogen, bubbles were generated differently. The round shape of the bubble is occurred in 77 K LN2. But the layer shape of bubble is occurred in 65 K LN2. When the bubbles present, the dielectric strength of liquid nitrogen is low. However, the breakdown patterns were different according to the electrode arrangement. AC breakdown voltage(BDV) was lower than the DC BDV due to the influence of bubbles. Therefore, the design of a high-voltage superconducting equipments should consider the bubbles.

Development of LnCP based Home Network System by using high level message between heterogeneous application software

  • Chung, Jong-Hoon;Wang, Dae-Sung;Lee, Sang-Kyun;Han, Sun-Mi;Roh, Young-Hoon;Kang, Min-Seok
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2004년도 ICCAS
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    • pp.903-907
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    • 2004
  • This paper introduces LnCP(Living Network Control Protocol)-based home network system and proposes high level message which is utilized between LnCP Home network Server and User Control Point. LnCP is very optimized protocol for digital home appliances. Then proposed system and implementation of these ideas are presented.

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우리나라의 밤 가격(價格) 및 국내소비량(國內消費量) 추정(推定)에 관(關)한 연구(硏究) (A Study on the Estimating Functions of Price and Domestic Consumption of Chestnut in South Korea)

  • 전준헌;이상식
    • Journal of the Korean Wood Science and Technology
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    • 제21권4호
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    • pp.29-34
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    • 1993
  • This study was carried out to estimate price and domestic consumption functions of chestnut using time series data for the period 1970~1989. Using a regression analysis method, price and domestic consumption functions of chestnut in Korea are estimated. The result of this study reveals that the optimum function of price for chestnut is PR= -249.33965 + 163532.56817 EX/POP-4.10177 PD+4.02877 DC+6056.98339 GDP/POP($R^2$=0.88207), and that optimum function of domestic consumption for chestnut is ln DC=14.97145+1.48279 ln PD/POP - 0.32853 ln GDP - 0.02337 ln PR - 0.12117 ln EX($R^2$=0.98689). On the ground that instability of prices make the income of producer and family finances of consumer unstable, the object of price-policy should be to stabilize price of chestnut in Korea.

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원자력용 316LN 스테인레스강의 탄화물 석출 거동

  • 오용준;류우석;윤지현;홍준화;국일현
    • 한국원자력학회:학술대회논문집
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    • 한국원자력학회 1995년도 춘계학술발표회논문집(2)
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    • pp.689-694
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    • 1995
  • 원자력용 316LN 스테인레스강의 입계탄화물 석출거동에 미치는 질소 및 Ti, B의 미량원소 영향을 시차열분석기(DSC)와 투과전자현미경(TEM)을 이용하여 관찰하였으며, 이들 결과와 예민화 특성과의 관계성을 분석하였다. Ti과 B의 첨가는 316LN 강의 탄화물 석출온도를 높이며, 탄화물 석출에 필요한 활성화에너지 값은 미첨가강에 비해 높았다. TEM/EDX 분석결과, 예민화된 316 LN 강은 M$_{23}$C$_{6}$ 탄화물이 입계에 석출되며 입계에서 Cr 고같층이 관찰되었다. 반면 Ti 및 B 첨가강은 7$50^{\circ}C$, 20시간 열처리 조건에서도 거의 입계석출물이 존재하지 않았으며 일부 소량 존재하는 입계 석출물은 EDX 분석결과 Mo-rich 상인 Laves 상으로 분석되었다. DSC와 TEM 분석 결과는 Oxalic 시험 및 Modified Strauss 시험에 의한 입계 부시시험결과와 잘 일치하였고, Ti 및 B의 첨가는 Cr의 확산을 저지시켜 입계탄화물의 석출 및 성장을 저지하는 역할을 하며, 316LN 강의 예민화 특성을 양호하게 하였다.

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Characterization of Ln0.8Sr0.2CoO3-δ (Ln=Gd, Nd, Pr, Sm, or Yb) as Cathode Materials for Low-Temperature SOFCs

  • Choi, Jung-Woon;Kang, Ju-Hyun;Kim, Han-Ji;Yoo, Kwang-Soo
    • 한국세라믹학회지
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    • 제43권12호
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    • pp.758-763
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    • 2006
  • Perovskites with nominal compositions $Ln_{0.8}Sr_{0.2}CoO_{3-\delta}$ (Ln=Gd, Nd, Pr, Sm, or Yb) were fabricated as cathode materials using a solid-state reaction method for low-temperature operating Solid-Oxide Fuel Cells (SOFCs). X-ray diffraction analysis and microstructure observation for the sintered samples were performed. The ac complex impedance was measured in the temperature range of $600-900^{\circ}C$ in air and fitted with a Solartron ZView program. The crystal structure, microstructure, electrical conductivity, and polarization resistance of $Ln_{0.8}Sr_{0.2}CoO_{3-\delta}$ were characterized systematically.

Type 316LN 강의 크리프 수명예측 파라메타의 표준오차 분석 (Standard Error Analysis of Creep-Life Prediction Parameters of Type 316LN Stainless Steels)

  • 김우곤;윤송남;류우석
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2004년도 춘계학술대회
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    • pp.19-24
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    • 2004
  • A number of creep data were collected and filed for type 316LN stainless steels through literature survey and experimental data produced in KAERI. Using these data, polynomial equations for predicting creep life were obtained for Larson Miller (L-M), Qrr-Sherby-Dorn (O-S-D) and Manson-Haferd (M-H) parametric methods. In order to find out the suitability for them, the relative standard error (RSE) and standard error of estimate (SEE) values were obtained by statistical process of creep data. The O-S-D parameter showed better fitting to creep-rupture data than the L-M or the M-H parameters, and the three parametric methods did not generate the large difference in the SEE and the RSE values.

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$Ca_{2-X}-Ln_{x}MnO_{4}$상의 합성과 결정구조 정밀화 {Ln=Gd, Nd, Pr, Sm} (Syntheses and structure refinement of $Ln_{x}MnO_{4}$ {Ln=Gd, Nd, Pr, Sm})

  • 서상일;이재열
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2000년도 하계학술대회 논문집
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    • pp.726-729
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    • 2000
  • Though L $a_{1+x}$S $r_{2-x}$M $n_2$ $O_{7}$ n=2 R-P phases have been well known to have CMR effect, it was generally believed that n=1 phase was insulating. But recently monolayered perovskite $Ca_{2-x}$L $n_{x}$Mn $O_4$phase has been reported to show magnetoresistance. In this study, layered perovskite $Ca_{2-x}$L $n_{x}$Mn $O_4$ (x=0, 0.5, Ln=Pr, Nd, Sm, Gd) phases were synthesized by solid state reaction and their structures were refined by Rietveld method. The space groups of $Ca_2$Mn $O_4$, N $d_{0.5}$C $a_{1.5}$Mn $O_4$phases were refined as C2cb and Fmmm, respectively.y.ely.y.y.y.y.y.y.

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Evaluation of Monkman-Grant Parameters for Type 316LN and Modified 9Cr-Mo Stainless Steels

  • Kim, Woo-Gon;Kim, Sung-Ho;Ryu, Woo-Seog
    • Journal of Mechanical Science and Technology
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    • 제16권11호
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    • pp.1420-1427
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    • 2002
  • The Monkman-Grant (M-G) and its modified parameters were evaluated for type 316LN and modified 9Cr-Mo stainless steels prepared with minor element variations. Several sets of creep data for the two alloy systems were obtained by constant-load creep tests in 550~650$\^{C}$ temperature range. The M-G parameters, m, m', C, and C' were proposed and discussed for the two alloy systems. The m value of the M-C relation was 0.90 in type 316LN steel and 0.84 in modified 9Cr-Mo steel. The m' value of the modified relation was 0.94 in type 316LN steel and 0.89 in 9Cr-Mo steel. Although creep fracture modes and creep properties between type 316LN and modified 9Cr-Mo steels showed a basic difference, the M-G and its modified relations demonstrated linearity quite well. The m' of modified relation almost overlapped regardless of the creep testing conditions and chemical variations in the two alloy systems, and the parameter m' was closer to unity than that of the M-G relation.