• 제목/요약/키워드: LMP2

검색결과 67건 처리시간 0.021초

Genetic Parameter Estimation of Carcass Traits of Duroc Predicted Using Ultrasound Scanning Modes

  • Salces, Agapita J.;Seo, Kang Seok;Cho, Kyu Ho;Kim, SiDong;Lee, Young Chang
    • Asian-Australasian Journal of Animal Sciences
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    • 제19권10호
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    • pp.1379-1383
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    • 2006
  • A total of 6,804 records for Duroc breed were collected from three farms registered at the Korean Animal Improvement Association (KAIA) from 1998 to 2004 of which both records from two ultrasound modes (A and B) were analyzed to estimate the variance components of carcass traits. Three carcass traits backfat thickness (bf), loin eye muscle area (lma) and lean meat percentage (lmp) were measured. These traits were analyzed separately as bf1, lma1 and lmp1 for ultrasound mode A and bf2, lma2 and lmp2 for ultrasound mode B with multiple trait animal model by using MTDFREML (Boldman et al., 1993). All the traits revealed medium heritability values. Estimated heritabilities for bf1, bf2, lma1, lma2, lmp1 and lmp2 were 0.45, 0.39, 0.32, 0.25, 0.28 and 0.39, respectively. Estimated genetic correlations for traits bf1 and bf2, lma1 and lma2, lmp1 and lmp2 were positive but low. Specifically, genetic correlations between bf1 and bf2 was 0.30 while the estimates for lean traits between lma1 and lma2 and between lmp1 and lmp2 were 0.15 and 0.18, respectively. Conversely, high negative genetic correlations existed between bf1 and the lean traits lma2, lmp2. Likewise, the estimated genetic correlations between lma1 and lma2 and lmp1 and lmp2 were low.

Association of an LMP2 Polymorphism with Acute Myeloid Leukemia and Multiple Myeloma

  • Ozbas-Gerceker, Filiz;Bozman, Nazli;Kok, Selcuk;Pehlivan, Mustafa;Yilmaz, Mehmet;Pehlivan, Sacide;Oguzkan-Balci, Sibel
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권11호
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    • pp.6399-6402
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    • 2013
  • Hematological malignancies (HM) are a group of neoplasms derived from the cells of the bone marrow and lymphatic system. Genetic factors leading to susceptibility to HM have been investigated for years but little is known yet. Low molecular weight polypeptide (LMP) 2 and LMP7 genes are important subunits of the immunoproteasome and play significant role in antigen presentation. The polymorphisms of LMP genes have been reported to be risk factors for various types of diseases. The aim of this study was to investigate the association of LMP2 and LMP7 polymorphisms with the occurrence of particular types of HM. A total of 132 patients with HM and 130 control subjects were investigated. No significant difference was obtained in the distribution of genotype and allele frequencies of LMP7 gene in HM patients and the control group. On the other hand, the prevalence of LMP2-AA genotype was found to be higher in acute myeolid leukemia (AML) patients while it was significantly lower in multiple myeloma (MM) cases than in the control subjects. Our results suggested that LMP7 could not be a risk factor for susceptibility to HM, whereas LMP2 polymorphisms could play a role in the development of AML and MM.

Isolation and Characterization of Listeria phages for Control of Growth of Listeria monocytogenes in Milk

  • Lee, Sunhee;Kim, Min Gon;Lee, Hee Soo;Heo, Sunhak;Kwon, Mirae;Kim, GeunBae
    • 한국축산식품학회지
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    • 제37권2호
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    • pp.320-328
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    • 2017
  • In this study, two Listeria bacteriophages, LMP1 and LMP7, were isolated from chicken feces as a means of biocontrol of L. monocytogenes. Both bacteriophages had a lytic effect on L. monocytogenes ATCC 7644, 15313, 19114, and 19115. Phages LMP1 and LMP7 were able to inhibit the growth of L. monocytogenes ATCC 7644 and 19114 in tryptic soy broth at $10^{\circ}C$ and $30^{\circ}C$. Nevertheless, LMP1 was more effective than LMP7 at inhibiting L. monocytogenes ATCC 19114. On the contrary, LMP7 was more effective than LMP1 at inhibiting L. monocytogenes ATCC 7644. The morphology of LMP1 and LMP7 resembled that of members of the Siphoviridae family. The growth of L. monocytogenes ATCC 7644 was inhibited by both LMP1 and LMP7 in milk; however, the growth of L. monocytogenes ATCC 19114 was only inhibited by LMP1 at $30^{\circ}C$. The lytic activity of bacteriophages was also evaluated at $4^{\circ}C$ in milk in order to investigate the potential use of these phages in refrigerated products. In conclusion, these two bacteriophages exhibit different host specificities and characteristics, suggesting that they can be used as a component of a phage cocktail to control L. monocytogenes in the food industry.

ADN 기반 추진제를 적용한 마이크로 단일추진제 추력기 성능 평가 (Performance Study of Micro Monopropellant Thruster with ADN-Based Propellant)

  • 김주원;허정무;백승관;김우람;조영민;이도윤;권세진
    • 한국추진공학회:학술대회논문집
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    • 한국추진공학회 2017년도 제48회 춘계학술대회논문집
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    • pp.757-763
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    • 2017
  • 본 연구에서는 50 mN급 마이크로 추력기를 활용하여, ADN 기반 추진제인 LMP-103S의 연소 실험을 수행하였다. 마이크로 추력기는 MEMS 공정 과정을 거쳐 감광유리로 제작하였다. LMP-103S 분해용 촉매로 $Pt/{\gamma}-Al_2O_3$를 사용하였다. 연소 실험 초기에 촉매 예열을 위해 90 wt.% 과산화수소를 주입하였으며, 이후 LMP-103S를 주입하여 연소 실험을 수행하였다. 실험 결과 백금 촉매 환경에서 LMP-103S의 점화가 이루어짐을 확인하였으며, 연소실 온도는 $650^{\circ}C$로 형성되었다.

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Anti-oxidation and Anti-wrinkling Effects of Jeju Horse Leg Bone Hydrolysates

  • Kim, Dongwook;Kim, Hee-Jin;Chae, Hyun-Seok;Park, Nam-Gun;Kim, Young-Boong;Jang, Aera
    • 한국축산식품학회지
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    • 제34권6호
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    • pp.844-851
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    • 2014
  • This study focused on the anti-oxidative and collagenase- and elastase inhibition effects of low molecular weight peptides (LMP) from commercial Jeju horse leg bone hydrolysates (JHLB) on pancreatin, via enzymatic hydrolysis. Cell viability of dermal fibroblasts exposed to UVB radiation upon treatment with LMP from JHLB was evaluated. Determination of the antioxidant activity of various concentrations of LMP from JHLB were carried out by assessing 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2-azino-bis-3-ethybenzothiazoline-6-sulphonic acid (ABTS) radical scavenging activity, ferric reducing antioxidant power (FRAP), and oxygen radical absorbance capacity (ORAC). The DPPH radical scavenging activity of LMP from JHLB (20 mg/mL) was 92.21% and ABTS radical scavenging activity (15 mg/mL) was 99.50%. FRAP activity (30 mg/mL) was $364.72{\mu}M/TE$ and ORAC activity (1 mg/mL) was $101.85{\mu}M/TE$. The anti-wrinkle potential was assessed by evaluating the elastase- and collagenase inhibition potential of these LMP. We found that 200 mg/mL of LMP from JHLB inhibited elastase activity by 41.32%, and 100 mg/mL of LMP from JHLB inhibited collagenase activity by 91.32%. The cell viability of untreated HS68 human dermal fibroblasts was 45% when exposed to a UVB radiation dose of $100mJ/cm^2$. After 24 h of incubation with $500{\mu}g/mL$ LMP from JHLB, the cell viability increased to 60%. These results indicate that LMP from JHLB has potential utility as an anti-oxidant and anti-wrinkle agent in the food and cosmetic industry. Additional in vivo tests should be carried out to further characterize these potential benefits.

열간 금형재의 이종재 마찰용접과 크리프 수명예측 (II) -크리프 수명예측 (Friction Welding of Dissimilar Hot Die Punch materials and Its Creep Life Prediction(II)-Creep Life Prediction by ISM)

  • 박일동;공유식;오세규;전태언
    • 한국해양공학회지
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    • 제15권2호
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    • pp.53-60
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    • 2001
  • It was confirmed that the life predictive equation by LMP and LMP-ISM are effective only up to 10$^2$hours and can not be used for long times of $10^3~10^5$ hours, but that by ISM can be used for long times creep life prediction with more reliability. The predictive creep life equation of ISM has better reliability than those by LMP and LMP-ISM, and its realizably is getting better for long time creep prediction($10^3~10^5$ h).

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ISM에 의한 압력용기용 고온재료의 크리프 수명예측 (Creep Life Prediction of Elevated Temperature Materials for Pressure Vessel by ISM)

  • 공유식;김헌경;오세규;임만배
    • 동력기계공학회지
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    • 제6권2호
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    • pp.40-47
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    • 2002
  • In this paper, friction welding optimization for 1Cr0.5Mo-STS304 (${\phi}14\;mm$), AE applications for the weld quality evaluation and the applications of various life prediction methods such as LMP (Larson-Miller Parameter) and ISM (initial strain method) were investigated : The creep behaviors of those steels and the friction welded joints under static load were examined by ISM combined with LMP at 400, 500, 550 and $600^{\circ}C$, and the relationship between these two kinds of phenomena was studied. The real-time predicting equations of elevated-temperature creep life (rupture time) under any creep stress at any elevated-temperature could be developed by LMP and LMP-ISM. It was confirmed that the life prediction equations by LMP and LMP-ISM are effective only up to 102 h and can not be used for long times of 103-106 h, but by ISM it can be used for long times creep prediction of more than 104 h with most reliability.

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사과의 성숙에 따른 Pectin질의 변화 (Changes in the Pectic Substance during Maturity of Apple)

  • 김영지;김창식
    • 한국식품영양과학회지
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    • 제17권1호
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    • pp.63-68
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    • 1988
  • Fuji 과실의 성숙에 따른 pectin 질의 변화를 조사하기 위하여 LMP (low methoxy pectin), HMP (high methoxy pectin) IAP (ionically associated pectin), CBP (covalently bounded pectin), methoxyl 및 구성당의 함량변화와 DE(degree of esterification)를 조사하였다. 그 결과 LMP+HMP와 IAP+CBP는 AIS(alcohol insoluble solid)의 각각 70%, 22%를 차지하였고 이들 성분은 성숙에 따라 다소 증가하였다. Pectose 질을 구성하는 중성당중 hexose는 LMP, HMP, IAP, CBP 다같이 $20{\sim}50%$가 감소하였는데 특히 Gal의 감소율은 63%이었다. Pentose는 $1{\sim}9%$가 증가하였고 uronic acid는 $2{\sim}4%$감소하였다. 그러나 HMP, CBP에서는 uronic acid의 상대적 함유비율은$3{\sim}5%$ 증가되었다.

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거래전략 및 Quadratic 혼잡비용을 고려한 LMP산정에 대한 연구 (LMP Calculation with Consideration of Transaction Strategy and Quadratic Congestion Cost Function)

  • 김재욱;정성훈;민경일;문영현
    • 전기학회논문지
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    • 제60권2호
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    • pp.257-265
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    • 2011
  • As the competitive market system has been introduced to the electrical power trade, the priority concern would be that the price of electrical power should be reasonable. It is because, when this rule is solid, we can avoid the distortion of competition and assure the greater efficiency in management. LMP(Locational Marginal Price) means marginal price at each bus. This components consist of energy, loss and congestion cost. At this point, the LMP result that is calculated by traditional model is changeable by the location of the slack and can not be used in bilateral Transaction. This paper proposed algorithm is proved its rationality and credibility by comparing the result of the simulation of virtual 6_bus system that is calculated by traditional method, and showed that the LMP components are changed according to the Transaction Strategy. Furthermore, It shows the effect of additional congestion cost on the transmission line that has bottle neck frequently by simulation.