• Title/Summary/Keyword: LMP2

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Genetic Parameter Estimation of Carcass Traits of Duroc Predicted Using Ultrasound Scanning Modes

  • Salces, Agapita J.;Seo, Kang Seok;Cho, Kyu Ho;Kim, SiDong;Lee, Young Chang
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.10
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    • pp.1379-1383
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    • 2006
  • A total of 6,804 records for Duroc breed were collected from three farms registered at the Korean Animal Improvement Association (KAIA) from 1998 to 2004 of which both records from two ultrasound modes (A and B) were analyzed to estimate the variance components of carcass traits. Three carcass traits backfat thickness (bf), loin eye muscle area (lma) and lean meat percentage (lmp) were measured. These traits were analyzed separately as bf1, lma1 and lmp1 for ultrasound mode A and bf2, lma2 and lmp2 for ultrasound mode B with multiple trait animal model by using MTDFREML (Boldman et al., 1993). All the traits revealed medium heritability values. Estimated heritabilities for bf1, bf2, lma1, lma2, lmp1 and lmp2 were 0.45, 0.39, 0.32, 0.25, 0.28 and 0.39, respectively. Estimated genetic correlations for traits bf1 and bf2, lma1 and lma2, lmp1 and lmp2 were positive but low. Specifically, genetic correlations between bf1 and bf2 was 0.30 while the estimates for lean traits between lma1 and lma2 and between lmp1 and lmp2 were 0.15 and 0.18, respectively. Conversely, high negative genetic correlations existed between bf1 and the lean traits lma2, lmp2. Likewise, the estimated genetic correlations between lma1 and lma2 and lmp1 and lmp2 were low.

Association of an LMP2 Polymorphism with Acute Myeloid Leukemia and Multiple Myeloma

  • Ozbas-Gerceker, Filiz;Bozman, Nazli;Kok, Selcuk;Pehlivan, Mustafa;Yilmaz, Mehmet;Pehlivan, Sacide;Oguzkan-Balci, Sibel
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6399-6402
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    • 2013
  • Hematological malignancies (HM) are a group of neoplasms derived from the cells of the bone marrow and lymphatic system. Genetic factors leading to susceptibility to HM have been investigated for years but little is known yet. Low molecular weight polypeptide (LMP) 2 and LMP7 genes are important subunits of the immunoproteasome and play significant role in antigen presentation. The polymorphisms of LMP genes have been reported to be risk factors for various types of diseases. The aim of this study was to investigate the association of LMP2 and LMP7 polymorphisms with the occurrence of particular types of HM. A total of 132 patients with HM and 130 control subjects were investigated. No significant difference was obtained in the distribution of genotype and allele frequencies of LMP7 gene in HM patients and the control group. On the other hand, the prevalence of LMP2-AA genotype was found to be higher in acute myeolid leukemia (AML) patients while it was significantly lower in multiple myeloma (MM) cases than in the control subjects. Our results suggested that LMP7 could not be a risk factor for susceptibility to HM, whereas LMP2 polymorphisms could play a role in the development of AML and MM.

Isolation and Characterization of Listeria phages for Control of Growth of Listeria monocytogenes in Milk

  • Lee, Sunhee;Kim, Min Gon;Lee, Hee Soo;Heo, Sunhak;Kwon, Mirae;Kim, GeunBae
    • Food Science of Animal Resources
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    • v.37 no.2
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    • pp.320-328
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    • 2017
  • In this study, two Listeria bacteriophages, LMP1 and LMP7, were isolated from chicken feces as a means of biocontrol of L. monocytogenes. Both bacteriophages had a lytic effect on L. monocytogenes ATCC 7644, 15313, 19114, and 19115. Phages LMP1 and LMP7 were able to inhibit the growth of L. monocytogenes ATCC 7644 and 19114 in tryptic soy broth at $10^{\circ}C$ and $30^{\circ}C$. Nevertheless, LMP1 was more effective than LMP7 at inhibiting L. monocytogenes ATCC 19114. On the contrary, LMP7 was more effective than LMP1 at inhibiting L. monocytogenes ATCC 7644. The morphology of LMP1 and LMP7 resembled that of members of the Siphoviridae family. The growth of L. monocytogenes ATCC 7644 was inhibited by both LMP1 and LMP7 in milk; however, the growth of L. monocytogenes ATCC 19114 was only inhibited by LMP1 at $30^{\circ}C$. The lytic activity of bacteriophages was also evaluated at $4^{\circ}C$ in milk in order to investigate the potential use of these phages in refrigerated products. In conclusion, these two bacteriophages exhibit different host specificities and characteristics, suggesting that they can be used as a component of a phage cocktail to control L. monocytogenes in the food industry.

Performance Study of Micro Monopropellant Thruster with ADN-Based Propellant (ADN 기반 추진제를 적용한 마이크로 단일추진제 추력기 성능 평가)

  • Kim, Juwon;Huh, Jeongmoo;Baek, Seungkwan;Kim, Wooram;Jo, Youngmin;Lee, Doyun;Kwon, Sejin
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2017.05a
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    • pp.757-763
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    • 2017
  • The combustion test of LMP-103S, a propellant based on ADN(Ammonium Dinitramide), was performed with a 50 mN scale micro-thruster. The micro-thruster was made with photosensitive glass using MEMS manufacturing process. $Pt/{\gamma}-Al_2O_3$ was used as a catalyst to decompose LMP-103S. After injecting 90 wt.% hydrogen peroxide into combustion chamber to preheat the catalyst, LMP-103S was injected for the combustion test. As a result, the ignition and combustion of LMP-103S was confirmed in platinum catalyst environment with the combustion chamber temperature going up to $650^{\circ}C$.

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Anti-oxidation and Anti-wrinkling Effects of Jeju Horse Leg Bone Hydrolysates

  • Kim, Dongwook;Kim, Hee-Jin;Chae, Hyun-Seok;Park, Nam-Gun;Kim, Young-Boong;Jang, Aera
    • Food Science of Animal Resources
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    • v.34 no.6
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    • pp.844-851
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    • 2014
  • This study focused on the anti-oxidative and collagenase- and elastase inhibition effects of low molecular weight peptides (LMP) from commercial Jeju horse leg bone hydrolysates (JHLB) on pancreatin, via enzymatic hydrolysis. Cell viability of dermal fibroblasts exposed to UVB radiation upon treatment with LMP from JHLB was evaluated. Determination of the antioxidant activity of various concentrations of LMP from JHLB were carried out by assessing 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2-azino-bis-3-ethybenzothiazoline-6-sulphonic acid (ABTS) radical scavenging activity, ferric reducing antioxidant power (FRAP), and oxygen radical absorbance capacity (ORAC). The DPPH radical scavenging activity of LMP from JHLB (20 mg/mL) was 92.21% and ABTS radical scavenging activity (15 mg/mL) was 99.50%. FRAP activity (30 mg/mL) was $364.72{\mu}M/TE$ and ORAC activity (1 mg/mL) was $101.85{\mu}M/TE$. The anti-wrinkle potential was assessed by evaluating the elastase- and collagenase inhibition potential of these LMP. We found that 200 mg/mL of LMP from JHLB inhibited elastase activity by 41.32%, and 100 mg/mL of LMP from JHLB inhibited collagenase activity by 91.32%. The cell viability of untreated HS68 human dermal fibroblasts was 45% when exposed to a UVB radiation dose of $100mJ/cm^2$. After 24 h of incubation with $500{\mu}g/mL$ LMP from JHLB, the cell viability increased to 60%. These results indicate that LMP from JHLB has potential utility as an anti-oxidant and anti-wrinkle agent in the food and cosmetic industry. Additional in vivo tests should be carried out to further characterize these potential benefits.

Friction Welding of Dissimilar Hot Die Punch materials and Its Creep Life Prediction(II)-Creep Life Prediction by ISM (열간 금형재의 이종재 마찰용접과 크리프 수명예측 (II) -크리프 수명예측)

  • 박일동;공유식;오세규;전태언
    • Journal of Ocean Engineering and Technology
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    • v.15 no.2
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    • pp.53-60
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    • 2001
  • It was confirmed that the life predictive equation by LMP and LMP-ISM are effective only up to 10$^2$hours and can not be used for long times of $10^3~10^5$ hours, but that by ISM can be used for long times creep life prediction with more reliability. The predictive creep life equation of ISM has better reliability than those by LMP and LMP-ISM, and its realizably is getting better for long time creep prediction($10^3~10^5$ h).

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Creep Life Prediction of Elevated Temperature Materials for Pressure Vessel by ISM (ISM에 의한 압력용기용 고온재료의 크리프 수명예측)

  • Kong, Y.S.;Kim, H.K.;Oh, S.K.;Lim, H.K.
    • Journal of Power System Engineering
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    • v.6 no.2
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    • pp.40-47
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    • 2002
  • In this paper, friction welding optimization for 1Cr0.5Mo-STS304 (${\phi}14\;mm$), AE applications for the weld quality evaluation and the applications of various life prediction methods such as LMP (Larson-Miller Parameter) and ISM (initial strain method) were investigated : The creep behaviors of those steels and the friction welded joints under static load were examined by ISM combined with LMP at 400, 500, 550 and $600^{\circ}C$, and the relationship between these two kinds of phenomena was studied. The real-time predicting equations of elevated-temperature creep life (rupture time) under any creep stress at any elevated-temperature could be developed by LMP and LMP-ISM. It was confirmed that the life prediction equations by LMP and LMP-ISM are effective only up to 102 h and can not be used for long times of 103-106 h, but by ISM it can be used for long times creep prediction of more than 104 h with most reliability.

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Changes in the Pectic Substance during Maturity of Apple (사과의 성숙에 따른 Pectin질의 변화)

  • Kim, Yeung-Ji;Kim, Chang-Sik
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.17 no.1
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    • pp.63-68
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    • 1988
  • The changes of methoxy content. compositional sugars. degree of esterification (DE) and pectic substances such as LMP (low methoxy pectin), HMP (high methoxy pectin) IAP (ionically associated pectin) and CBP (covalently bounded pectin) of Fuji apple were investigated during maturity. The contents of LMP+HMP and IAP+CBP in alcohol insoluble solid(AIS) were 70% and 20%. respectively. These pectic substances were increased slightly during maturity. The reductions of hexose and uronic acid were Iron 20-50% and from 2-4%, respectively, but the inclosed of pentose was from 1-9% in LMP, HMP, IAP and CBP during maturity of Fuji apple. The galactose was decreased significantly among hexose. Whereas the relative ratio of uronic acid in HMP and CBP was increased.

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LMP Calculation with Consideration of Transaction Strategy and Quadratic Congestion Cost Function (거래전략 및 Quadratic 혼잡비용을 고려한 LMP산정에 대한 연구)

  • Kim, Jae-Wook;Jung, Sung-Hun;Min, Kyung-Il;Moon, Young-Hyun
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.60 no.2
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    • pp.257-265
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    • 2011
  • As the competitive market system has been introduced to the electrical power trade, the priority concern would be that the price of electrical power should be reasonable. It is because, when this rule is solid, we can avoid the distortion of competition and assure the greater efficiency in management. LMP(Locational Marginal Price) means marginal price at each bus. This components consist of energy, loss and congestion cost. At this point, the LMP result that is calculated by traditional model is changeable by the location of the slack and can not be used in bilateral Transaction. This paper proposed algorithm is proved its rationality and credibility by comparing the result of the simulation of virtual 6_bus system that is calculated by traditional method, and showed that the LMP components are changed according to the Transaction Strategy. Furthermore, It shows the effect of additional congestion cost on the transmission line that has bottle neck frequently by simulation.