• Title/Summary/Keyword: LINKED SYSTEM

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Isolation and Characterization of Biopolymers Extracted from the Bark of Acanthopanax sessiliflorus and Their Anticomplement Activity

  • Jeong Sang-Chul;Yang Byung-Keun;Jeong Yong-Tae;Rao Koyyalamudi Sundar;Song Chi-Hyun
    • Journal of Microbiology and Biotechnology
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    • v.17 no.1
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    • pp.21-28
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    • 2007
  • The crude biopolymer (AS-S1) and endobiopolymer (AS-S2) were isolated from the dry stem bark of Acanthopanax sessiliflorus and tested for anti complement activity. The two potent anticomplement biopolymers, AS-1 and AS-2-Fr.I, were isolated by the combination of ion-exchange chromatography and gel filtration methods from the endo-biopolymers (AS-S2). The anticomplement activity of AS-1 (MW 12 kDa) and AS-2-Fr.I (MW 180 kDa) were found to be 84.4% and 100.0%, respectively, at the concentration of $25{\mu}g/ml$. Activated pathway of the complement system occurred in both classical and alternative pathways, as evidenced by crossed immunoelectrophoresis(CIEP), where a major pathway was detected to be the classical one. It was found that the anticomplement activities of the periodate oxidized were decreased significantly, but those of pronase digested biopolymers of AS-1 and AS-2-Fr.I were decreased very little. The AS-1 contained 2,4,6-tri-O-methyl-D-glucitol, 2,3,6-tri-O-methyl-D-galacitol, and 2,3,6-tri-O-methyl-D-galacitol, which indicated that AS-1 contained a $(1{\rightarrow}3),\;(1{\rightarrow}4)-linked$ glucopyranosyl residue and a $(1{\rightarrow}4)-linked$ galactosyl residue. AS-2-Fr.I contained mainly 2,4-di-O-methyl-D-mannitol and 2,3,4-tri-O-methyl-D-galacitol, which contained $(1{\rightarrow}3),\;(1{\rightarrow}6)$ linked mannosyl and $(1{\rightarrow}6)$ linked galactosyl residues.

Development of mobile, online/offline-linked math learning content to promote group creativity (집단창의성 발현을 위한 모바일, 온/오프라인 연계 수학 학습 콘텐츠 개발)

  • Kim, Bumi
    • Journal of the Korean School Mathematics Society
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    • v.25 no.1
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    • pp.39-60
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    • 2022
  • In this study, in order to support the expression of group creativity of high school students, we developed mathematics learning contents linked with mobile and online/offline that obtain the maximum and minimum values of the function within a limited range. This learning content was developed in connection with the 'environment', a cross-curricular learning topic. We explored the concept of group creativity in school mathematics. Its manifestation process, elements of group creativity expression process, and mobile and on/offline implementation functions were also explored. Then, we developed a hybrid app, 'Making the Best Box that Thinks of the Earth', which can express group creativity through mobile and online/offline-linked cooperative learning. A learning management system (LMS) and a teaching and learning guidance plan were also developed to efficiently operate mobile and online/offline-linked math learning using the app in schools. Our study found that the hybrid app, 'Creating the Best Box that Thinks of the Earth', was suitable for promoting collective fluency and collective sophistication based on complementary-metacognitive interaction.

Is a New Public Medical School Linked to Compulsory Service Necessary to Strengthen Public Health Care in Korea?: Who Wants to Build a New Public Medical School Linked to Compulsory Service? And Why? (우리나라 공공의료 강화를 위해 공공의대는 꼭 필요한가?: 누가, 왜 공공의대를 만들려 하는가?)

  • Han, Hee Chul
    • Korean Medical Education Review
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    • v.24 no.1
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    • pp.18-34
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    • 2022
  • The purpose of this study is to clarify the background of the controversial attempt to establish a new public medical school linked to compulsory service as a means of strengthening public healthcare in Korea, and to raise anticipated problems with possible solutions. In Korea, healthcare is predominantly provided by the private sector focused on medical care, rather than public healthcare, even under the national health insurance system. The government has been mainly in charge of public health and unmet medical services from a residual perspective, but health inequalities still exist. To resolve this issue, the government created the concept of public health and medical service (PHMS) from a universal perspective and tried to strengthen the infrastructure of public healthcare and to foster core PHMS doctors by establishing a new public medical school linked to compulsory service in medically vulnerable areas. This study investigated the reality and concept of the new public medical school planned by the government, and identified problems such as the possibility of obtaining accreditation and evaluation before its establishment, the side effects of dividing doctors' roles, the waste of huge amounts of resources, and insensitive policies. In conclusion, in order to resolve health inequalities in Korea, we need to train doctors through medical school education that strengthens the social responsibility of doctors along with strengthening public healthcare infrastructure, and to provide a better environment for doctors working in medically vulnerable areas through sophisticated policies.

Development of C2 Virtual Linked Simulator For Engineering and Engagement Level Battle Experimentation (공학-교전급 전투실험을 위한 C2 가상모의 연동 시뮬레이터 개발)

  • Lee, Sangtae;Lee, Seungyoung;Hwang, Kun-Chul;Kim, Saehwan;Lee, Kyuhyun
    • Journal of the Korea Society for Simulation
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    • v.22 no.4
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    • pp.11-19
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    • 2013
  • The Korean naval weapon systems, combat experiments establish the concept of Battle operations, and create the future of the new weapons system. Doctrine development and training as well as ranging from experiments for evaluate the performance of mission operations for combat experiments are used. The battle lab is effectively support tool for the Korean Naval battle experiments. The battle lab is through a dedicated testing facility and to build efficient and effective simulation-based acquisition supporting environment. In this paper, the ship / submarines C2 operations virtual simulator was developed to support the concept of Battle operations of naval combat experiments in training and tactical development. The ship C2 operations virtual simulator makes the anti-ship and anti-aircraft the engagement scenario for performed experiments using the SADM. The submarines C2 operations virtual simulator makes the anti-submarine engagement scenario for performed experiments using EAS. EAS System was created before reuse. EAS system by modifying the additional interfaces HLA-RTI has been reused. Reflected in the tactics and training after analysis of the results through the battle experiment. Also increase training fidelity through operator involvement. The anti-ship and anti-aircraft system architecture (SADM) and anti-submarine system architecture (EAS) requires unique design of system framework since two separate architectures should be integrated into a system. An C2 virtual linked architecture was used to integrate different system architecture. A C2 virtual linked software framework, designed that have integrated protocol for battle experimental linkage and battlefield visualization environment.

A Study on the Multiple Texture Rendering System for 3D Image Signal Recognition (3차원 영상인식을 위한 다중영상매핑 시스템에 대한 연구)

  • Kim, Sangjune;Park, Chunseok
    • Journal of the Society of Disaster Information
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    • v.12 no.1
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    • pp.47-53
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    • 2016
  • Techniques to be developed in this study is intended to apply to an existing integrated control system to "A Study on the multiple Texture Rendering system for three-dimensional Image Signal Recognition" technology or become a center of the building control system in real time video. so, If the study plan multi-image mapping system developed, CCTV camera technology and network technology alone that is, will be a number of security do not have to build a linked system personnel provide services that control while the actual patrol, the other if necessary systems and linked to will develop a system that can reflect the intention Ranger.

A Location Recognition System of RFID Tag for Parking Control (주차관제를 위한 RFID 태그 객체의 위치 인식 시스템)

  • Kang, Ku-An;Kim, Jin-Deog
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.1
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    • pp.99-107
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    • 2008
  • Recently route guiding system using GPS is spread widely. In the parking management system of complex mall, RFID is mainly used to control status of parking lots. However, in a case that a vehicle only with RFID tag enters into small market-populated district with service of parking lots, there is no parking route guiding system optimized with information of real tine status of parking lots and the system only with GPS can't provide a function of using real time status of parking lots. This paper proposes a location recognizing method of RFID tag object for parking control system to integrated several parking lots in the business district and database-linked route guiding system optimized for parking. The proposed location recognizing method makes the search of optimized parking route possible by abstracting decoding order of tag and antenna number and recognizing direction of tag linked with database. Ihe implemented system that is composed of RFID tag, reader, middleware, server, parking lot clients and mobile clients shows that the proposed method works well and it will be useful for integrated parking control system.

Big Data based Tourist Attractions Recommendation - Focus on Korean Tourism Organization Linked Open Data - (빅데이터 기반 관광지 추천 시스템 구현 - 한국관광공사 LOD를 중심으로 -)

  • Ahn, Jinhyun;Kim, Eung-Hee;Kim, Hong-Gee
    • Management & Information Systems Review
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    • v.36 no.4
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    • pp.129-148
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    • 2017
  • Conventional exhibition management information systems recommend tourist attractions that are close to the place in which an exhibition is held. Some recommended attractions by the location-based recommendation could be meaningless when nothing is related to the exhibition's topic. Our goal is to recommend attractions that are related to the content presented in the exhibition, which can be coined as content-based recommendation. Even though human exhibition curators can do this, the quality is limited to their manual task and knowledge. We propose an automatic way of discovering attractions relevant to an exhibition of interests. Language resources are incorporated to discover attractions that are more meaningful. Because a typical single machine is unable to deal with such large-scale language resources efficiently, we implemented the algorithm on top of Apache Spark, which is a well-known distributed computing framework. As a user interface prototype, a web-based system is implemented that provides users with a list of relevant attractions when users are browsing exhibition information, available at http://bike.snu.ac.kr/WARP. We carried out a case study based on Korean Tourism Organization Linked Open Data with Korean Wikipedia as a language resource. Experimental results are demonstrated to show the efficiency and effectiveness of the proposed system. The effectiveness was evaluated against well-known exhibitions. It is expected that the proposed approach will contribute to the development of both exhibition and tourist industries by motivating exhibition visitors to become active tourists.

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Suggestions for Cost Improvement of High concentration Linked Treatment in Municipal Wastewater Treatment Plant (하수처리장에서의 연계처리수 요금 개선에 따른 경제성 분석)

  • Lee, Jiwon;Gil, Kyungik
    • Journal of Wetlands Research
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    • v.22 no.2
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    • pp.139-144
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    • 2020
  • Recently, high-concentration linked wastewater has been introduced into a nearby municipal wastewater treatment plants(MWTPs), but it is difficult to MWTP in local governments due to an unreasonable linked treatment charge system, and there is insufficient evidence or data to prove this. However, the MWTP, which is a national essential infrastructure, is generally exempt from the preliminary feasibility study, so there have been no cases where economic evaluation was conducted. Therefore, we proposed an improvement plan that can compensate for the disadvantages of the existing linked processing charges through previous studies. In this study, a comparative evaluation of how much economic feasibility can be improved compared to the existing ones when applying the improvement plan by conducting an economic analysis. For this, reference was made to the preliminary feasibility assessment data of the existing environmental facilities and the cost factors and benefit factors established during the modernization of the old sewage treatment facilities. As a result of the study, the B/C(Benefit/cost) value was quite low in the past, but when the improvement proposal proposed by the researchers was applied, it was confirmed that the B/C value increased close to 1. Therefore, it is considered to be very reasonable to calculate the linkage processing charge according to the linked wastewater load proposed by the researchers.

Novel substrate specificity of a thermostable β-glucosidase from the hyperthermophilic archaeon, Thermococcus pacificus P-4 (초고온 고세균 Thermococcus pacificus P-4로부터 내열성 β-glucosidase의 새로운 기질 특이성)

  • Kim, Yun Jae;Lee, Jae Eun;Lee, Hyun Sook;Kwon, Kae Kyoung;Kang, Sung Gyun;Lee, Jung-Hyun
    • Korean Journal of Microbiology
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    • v.51 no.1
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    • pp.68-74
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    • 2015
  • Based on the genomic analysis of Thermococcus pacificus P-4, we identified a putative GH1 ${\beta}$-glucosidase-encoding gene (Tpa-glu). The gene revealed a 1,464 bp encoding 487 amino acid residues, and the deduced amino acid residues exhibited 77% identity with Pyrococcus furiosus ${\beta}$-glucosidase (accession no. NP_577802). The gene was cloned and expressed in Escherichia coli system. The recombinant protein was purified by metal affinity chromatography and characterized. Tpa-Glu showed optimum activity at pH 7.5 and $75^{\circ}C$, and thermostability with a half life of 6 h at $90^{\circ}C$. Tpa-Glu exhibited hydrolyzing activity against various pNP-glycopyranosides, with kcat/Km values in the order of pNP-${\beta}$-glucopyranoside, pNP-${\beta}$-galactopyranoside, pNP-${\beta}$-mannopyranoside, and pNP-${\beta}$-xylopyranoside. In addition, the enzyme exhibited exo-hydrolyzing activity toward ${\beta}$-1,3-linked polysaccharide (laminarin) and ${\beta}$-1,3- and ${\beta}$-1,4-linked oligosaccharides. This is the first description of an enzyme from hyperthermophilic archaea that displays exo-hydrolyzing activity toward ${\beta}$-1,3-linked polysaccharides and could be applied in combination with ${\beta}$-1,3-endoglucanase for saccharification of laminarin.

A Study on Development of Residential-linked Pension Insurance for Rural Living after Retirement - Decisive insuring factors and the service demand of potential consumers - (은퇴 후 농촌거주를 위한 주택연동형 연금보험 개발에 관한 기초연구 - 잠재 수요자의 보험가입조건 및 서비스 요구도 분석)

  • Hong, Hyung-Ock;Kim, Jung-In;Im, Sang-Bon
    • Journal of Families and Better Life
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    • v.26 no.3
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    • pp.37-52
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    • 2008
  • The purpose of this study was to provide the valid data about residential-linked pension insurance development. The development was a part of national housing projects, which was an incentive for rural living of retired people, in order to relieve residential issues of elderly and revitalize rural communities by residents moving from cities. The insuring intent, decisive insuring factors and the residential service demand degree of people preparing retirement were analyzed. Data was collected in October, 2007. 364 Sample Subjects lived in Seoul Metropolitan area. Firstly, more than 90% of respondents had intention to purchase a residential-linked pension insurance and about 50% of them necessarily desired receiving premium for moving in. This indicated that it could be developed as an insurance which helped to meet housing expenses by housing-linked system, and in the mean time, it met the original purpose of pension insurance as the pension benefit could be guaranteed for all the insurance subscribers. Secondly, the respondents, whose income and private assets were higher, were able to pay more for insurance compared to average. Therefore, It was necessary to regulate monthly insurance bill and the payment period according to asset states of insurance subscribers after establishing certain amount of total insurance payment. Thirdly, by and large, it indicated the tendency that the less they prepare for older age the later they wanted to move into the pension insurance residence. It was inferred that in the case of insufficient preparation for older age, people preferred preparing behind time by postponing move in to moving in early to enjoy retired life, due to uncertainties. lastly, the respondents understood the significance of health, medical treatment and emergency management service and these two services were preferred as essential provided services. Because of the necessity of developing residential-linked pension insurance was found to be positive, further research to find the real cost, directives for operation and institutional support for this type of pension insurance might be needed.