• Title/Summary/Keyword: LG Chem

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High Performance OLEDs with a New Device Structure

  • Noh, Jeoung-Kwen;Kang, Min-Soo;Kim, Jong-Seok;Lee, Jung-Hyoung;Ham, Yun-Hye;Kim, Jung-Bum;Son, Seh-Wan
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08a
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    • pp.1011-1013
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    • 2007
  • We report the fabrication of a new inverted OLED devices having potential to be used for both AMOLED and lighting applications.

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Inverted OLED Structure for 3.5 inch Full Color AMOLED Display on a-Si TFT Backplane

  • Park, Jae-Hee;Park, Jae-Young;Hwang, Kwang-Jo;Choi, Hee-Dong;Myoung, Nho-Hoon;Lee, Seok-Jong;Park, Seung-Chul;Kim, Jung-Bum;Hahm, Yun-Hye;Noh, Jeoung-Kwen;Lee, Jung-Hyoung;Kim, Jong-Seok;Kang, Min-Soo
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08a
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    • pp.51-54
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    • 2007
  • Top-emission 3.5 inch qVGA IOD (Inverted AMOLED) was fabricated with inverted EL structure driven by a-Si TFT backplane. In order to get stable driving TFT, we used FCP(Field Control Plate) layer which was connected with the source of the driving TFT. And we developed planarization process to planarize the cathode layer which was the bottom layer of inverted OLED. Our unique IOD structure is “a-Si TFT/ Al(Cathode)/ LiF/ LG-201(ETL)/ EML(RGB)/ HTL/ LG-101(HIL & Buffer layer)/ IZO(Anode)”. LG-201(ETL) layer was studied for more efficient electron injection from cathode to EML, and LG-101(HIL & Buffer layer) covered by IZO anode was also explored for decreasing the EL surface damage.

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In vivo Efficacy of LB20304a against Experimental Respiratory Tract Infection in Mice (생쥐의 호흡기 감염에 대한 퀴놀론계 항생제 LB20304a의 치료 효과)

  • An, Mi-Jeong;Kim, Mu-Yong;Baek, Gyeong-Suk;Kim, In-Cheol;Gwak, Jin-Hwan
    • YAKHAK HOEJI
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    • v.40 no.4
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    • pp.438-441
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    • 1996
  • The therapeutic activity of LB20304a was examined on experimental respiratory tract infection (RTI) caused by Klebsiella pneumoniae DT-S in mice. A single oral dose of LB 20304a (1.2mg/mouse) showed a rapid bacteriocidal activity in lung tissue at 4,7 and 24h after administration of drug. The in vivo activity of LB20304a was comparable to that of ciprofloxacin against K. pneumoniae infection, although in vitro MIC of LB20304a was four-fold higher than that of ciprofloxacin.

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Effect of a New Fluoroquinolone LB20304a on Microflora of Caecum in Mice (새로운 플루오로퀴놀론계 항생제 LB20304a가 생쥐의 맹장내 세균총에 미치는 영향)

  • Ahn, Mi-Jeong;Paek, Kyoung-Sook;Kim, Mu-Yong;Kim, In-Chull;Kwak, Jin-Hwan
    • YAKHAK HOEJI
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    • v.40 no.3
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    • pp.343-346
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    • 1996
  • The influence of LB20304a, a new fluoroquinolone antibiotic agent, on microflora of caecum in mice was compared with those of ciprofloxacin and piperacillin after administration of drugs for 5 days. Selective medium (CCFMA) was used for the isolation of Clostridium difficile from the specimens of mouse caecum. The emergence of C. difficile in mouse caecum induced by LB20304a was lower than that by ciprofloxacin or piperacillin at day 1 and day 7 after completing administration of drugs.

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Pharmacolgocial Characterization of LB50016, N-(4-Amino)Butyl 3-Phenylpyrrolidine Derivative, as a New 5-HT_{1A}Receptor Agonist

  • Lee, Chang-Ho;Oh, Jeong-In;Park, Hee-Dong;Kim, Hee-Jin;Park, Tae-Kyo;Kim, Jae-Soon;Hong, Chang-Yong;Lee, Seok-Jong;Ahn, Kyo-Han;Kim, Yong-Zu
    • Archives of Pharmacal Research
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    • v.22 no.2
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    • pp.157-164
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    • 1999
  • LB50016 was characterized as a selective and potent$ 5-HT_{1A}$ receptor agonist and evaluate it anxiolytic and antidepressant activities. It shows high affinity for $ 5-HT_{1A}$receptor, moderate affinity for $\alpha$2 adrenergic and $ 5-HT_{2A}$receptors and no significant affinity for other receptors tested. Hypothermia and increased serum corticosterone level were observed in LB50016-treated rats, which are mediated mostly by post synaptic $ 5-HT_{1A}$ receptor activation. In the mouse forced swim model for depression, LB50016-elicited dose-dependent reductions in immobility time, showing $ED_{50}$ of approximately 3 mg/kg i.p., which was blocked by pretreatment of NAN-190, $ 5-HT_{1A}$antagonist. In face-to-face test for anxiolytic activity in mice, estimated $ED_{50}$ was 2 mg/kg, i.p.. In isolation-induced aggression test with mice, fifty-fold increases in latency to attack were observed at 30 min and last up to 4 h after LB50016 treatment (3 mg/kg, i.p.). Taken together, LB50016-induced pharmacological activities are mediated by activation of $ 5-HT_{1A}$receptors, offering an effective therapeutic candidate in the management of anxiety and depression in humans.

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