• BMB Reports
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• v.40 no.5
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• pp.814-824
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• 2007

Liver cirrhosis (LC) is defined as comprising diffuse fibrosis and regenerating nodules of the liver. The biochemical and anatomical dysfunction in LC results from both reduced liver cell number and portal vascular derangement. Although several studies have investigated dysregulated genes in cirrhotic nodules, little is known about the genes implicated in the pathophysiologic change of LC or about their relationship with the degree of decompensation. Here, we applied cDNA microarray analysis using 38 HBsAg-positive LC specimens to identify the genes dysregulated in HBV-associated LC and to evaluate their relation to disease severity. Among 1063 known cancer- and apoptosis-related genes, we identified 104 genes that were significantly up- (44) or down- (60) regulated in LC. Interestingly, this subset of 104 genes was characteristically correlated with the degree of decompensation, called the Pugh-Child classification (20 Pugh-Child A, 10 Pugh-Child B, and 8 Pugh-Child C). Patient samples from Pugh-Child C exhibited a distinct pattern of gene expression relative to those of Pugh-Child A and B. Especially in Pugh-Child C, genes encoding hepatic proteins and metabolizing enzymes were significantly down-regulated, while genes encoding various molecules related to cell replication were up-regulated. Our results suggest that subsets of genes in liver cells correspond to the pathophysiologic change of LC according to disease severity and possibly to hepatocarcinogenesis.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2009.11a
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• pp.161-161
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• 2009

Ion bombarded inorganic materials for LC alignment has been researched as it provides controllability in a nonstop process for producing high-resolution displays. Many optically transparent insulators such as $SiOx$ and a-C:H have been investigated as potential candidates for inorganic alignment materials. Even so, LC orientation on a new material with superior capacity is required to produce high-performance displays. Many inorganic materials with high permittivities can reduce the voltage losses due to the LC alignment layer that are a trade-off for its capacitance. The minimum voltage for device operation can be applied to the LC under low external voltage using these materials. This means that low power consumption for LCD applications can be achieved using a high-k alignment structure in which the LC can be driven effectively with a low threshold voltage. Among the many other potential high-k oxides, HfO2 is considered to be one of the most promising due to its remarkable properties of high dielectric constant, relatively low leakage current, large band gap (5.68 eV), and high transparency. Due to these characteristics, HfO2 can be used in LC alignment to increase the capacitance of the inorganic alignment layer for low-voltage driving of LCs.

• Analytical Science and Technology
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• v.9 no.1
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• pp.1-12
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• 1996

The thermally labile compounds with hydroxyl group generate the [${MNH_4}^+$] ion, [$MH^+$] and [$MH^+-OH$] ion by ion-molecule reaction in LC/TSP/MS. But these ions create the trouble in the estimation of molecular weight of an unknown compound because the margin of [${MNH_4}^+$] ion and [$MH^+$] ion is same to that of [$MH^+$] ion and [$MH^+-OH$] ion. If it is compensated for the results by using of the $CF_3COOD+NH_4OH$ LC eluent, the molecular weight of analyte will be able to be confirmed. And this study was tried to recognize whether the fragment ions of thermally labile compound are generated by electron impact or by thermal degradation in ion source.

• 한국정보디스플레이학회:학술대회논문집
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• 2006.08a
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• pp.864-867
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• 2006

In order to satisfy with the clear visibility without any difficulties such as blurring and tailing, the high refreshing rate technology and fast response time of LC itself were applied to TFT-LCDs. In proportion to the decrease of holding time of 1 frame, the fast transition of LC behavior was necessary to both maintain the luminance and minimize the tailing appearance. The introduction of a new LC mixture for faster response times was realized by the good combination of newly introduced dielectrically neutral LC material so called 'Super Low Viscosity' (SLV) and highly polar $CF_2O-linkage$ LC material. This resulted in about a 20% reduction in the ${\gamma}_1$ of the new LC mixture compared to the references. In accordance with a new LC mixture with low ${\gamma}_1$, fast response time of 5ms has been made for S-IPS LCD TV application. Consequently, by applying the high frame frequency of 120Hz driving alongside the 5ms response time characteristics, the MPRT value was reduced by half.

• KSBB Journal
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• v.9 no.2
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• pp.115-121
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• 1994

A Purification device with 30-channel free-flow electrophoresis was assembled to treat samples of 240m1 volume for purification of lentil lectin (LcH) from lentil seeds with no impurities in a silverstained PAGIEF gel. HEPES(50mM)-Ttis(50mM), Cycloserine(50mM)-urea(3M), Histidine(50mM)-urea(3M) were used as ampholytea among which Histidine(50mM)-urea(3M) (pI 7.65) was found best in resolution. LcH is known to be present in the form of LcH-A, LcH-B and the complex of the two. The complex, however, disappeared when urea was added in the ampholytes, which suggested that the complete purification of two isolectins is possible using the present multistep purificaton device.

• The Transactions of the Korean Institute of Power Electronics
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• v.11 no.4
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• pp.313-320
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• 2006

In this paper, a design approach of LC trap filter for output side harmonic reduction of single phase NPC multilevel inverter is proposed, and THD of the output voltage and harmonic FFT of the output current are analyzed. The proposed filter consists of a conventional LCR filter cascaded with an LC trap filter and it is tuned to inverter switching frequency. A NPC multilevel inverter inverter is used an inverter system for high power application and DSP(TMS320C31) is used for the controller. The effectiveness of the proposed system confirmed through simulation and experimental results.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.11 no.6
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• pp.671-677
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• 2018

In this paper, we investigated the vertical alignment characteristics of liquid crystals (LCs) on fluorinated self-assembled monolayers (FSAMs). For comparison, a commercialized homeotropic polyimide (PI) layer was used as an LC alignment layer. We confirmed the successful deposition of FSAMs and the change of FSAMs before and after rubbing treatment through contact angle measurement and atomic force microscopy. The optical transmittance spectrum of the FSAMs is similar to that of the homeotropic PI layer, which is a superior optical characteristic applicable to LC devices. When FSAMs were applied to the vertically aligned (VA) LC cell, uniform and vertical LC alignments were achieved. In addition, the voltage-transmittance characteristic of VA LC cell with FSAMs was superior to that of VA LC cell with the conventional homeotropic PI layers. These results indicate that the FSAMs are suitable as the homeotropic LC alignment layer for enhanced LC devices.

• Journal of Distribution Science
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• v.21 no.9
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• pp.115-121
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• 2023

Purpose: This study aimed to deal with disputes between the seller and the buyer in connection with the Letter of Credit (LC) in a sales contract. The Contracts for the International Sale of Goods (CISG) provides the rules on the fundamental breaches which can lead to termination of the sales contract but the CISG is not enough to govern issues arising from the LC disputes when the sales contract is not clear about the payment terms. This paper tried to find some solutions to the disputes by considering international rules, such as the Principles of European Contract Law (PECL). Research design, data and methodology: The methodology applied in this study was an analysis of some court decisions and extended literature review. Results: The study revealed that in contracts for the sale of international goods, the buyer was obliged to open an LC as manner of payment. If the buyer failed to open an LC or amend the terms of the LC, the seller could avoid the contract because this could deprive the seller's expected interest. Conclusions: Few studies in Korea have been comprehensively analyzed in terms of the obligations of regarding the LC with respect to the CISG in court cases. This study suggests safeguarding the buyer and seller when the LC is considered absolute or conditional.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2023.05a
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• pp.151-152
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• 2023

This study investigates the effect of nano-silica and nano-calcite on the hydration properties and mechanical performance of limestone calcined clay cement (LC³) paste. The pastes were synthesized by replacing limestone with nano-silica and nano-calcite in order to enhance the mechanical properties in both early and late stages of hydration. The nano-calcite enhanced the strength of LC³ pastes at 1 day of hydration, however, the strength decreased compared to the ordinary LC³ pastes afterwards due to excessive amount of carboaluminate produced in the pastes. On the other hand, nano-silica improved the mechanical properties of LC³ pastes at all ages of hydration. This is mainly due to the nucleation effect and pozzolanic reaction of nano-silica, affecting the early age and late ages of hydration, respectively. The nucleation effect of both nanomaterials were confirmed by the analysis of hydration heat, supporting the enhanced early age strength of nanomaterial incorporated LC³ pastes. Furthermore, the dense matrix was shown in the pore size distribution, and the increased C-S-H due to the pozzolanic reaction evidence the improved compressive and splitting tensile strength of nano-silica incorporated LC³ pastes.

• Korean Journal of Materials Research
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• v.15 no.4
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• pp.233-239
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• 2005

In this study, the effects of Pd buffer layer on the oxidation resistance of Pt modified-pack aluminized Inconel 738LC, used for gas turbine, were investigated. Pd was electroplated on Inconel 738LC, and Pt was electroplated on the electroplated Pd surface. Thus, the thickness of electroplated Pt/Pd was $10\;{\mu}m$ and the atomic ratio of Pt : Pd was about 6 : 4. After Pt/Pd electroplating, Inconel 738LC was pack aluminized to form the oxidation resistant layer. To investigate the oxidation resistance of Pt/Pd modified-pack aluminized Inconel 738LC, iso-thermal oxidation and cyclic oxidation were performed. The iso-thermal oxdation and the cyclic oxidation data indicated that the Pt/Pd modified-pack aluminized Inconel 738LC was more oxidation resistant than the Pt modified-pack aluminized Inconel 738LC. It was thought that the difference of thermal expansion coefficient between Inconel 738LC and Pt was lowered by the Pd buffer layer.