• 산업융합연구
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• 제22권2호
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• pp.97-103
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• 2024

본 연구의 목적은 비만 뇌졸중 환자의 균형 훈련이 체성분과 균형 능력 회복에 미치는 영향을 살펴보는 것이었다. 운동 프로그램은 비만군과 정상 체중 군을 동일하게 실험군(obesity)과 대조군(정상체중)으로 나누어 하루 30분, 일주일에 5일 동안 균형 훈련을 실시했다. 실험군과 대조군 모두 사전, 사후 체성분과 BSS(Biodex Medical Systems)를 8주간 수집하였다. 그 결과 그룹 내 체성분 자료를 비교해 보면 비만군은 모든 매개변수에서 유의한 차이를 보였다(p<.05). 또한 그룹 간 모든 매개변수 간에도 통계적인 차이를 보였다(p<.05). LOS(Limits Of Stability)의 그룹 내 자료를 비교해 보면, 비만군은 '후면'과 '좌측'을 제외한 모든 매개변수에서 유의한 차이를 보였다(p<.05). 그룹 간 자료에서 '전방' 매개변수는 유의한 차이를 보였다. PS(Posture Stability)의 그룹 내 자료를 비교해 보면, 비만군은 모든 매개변수에서 유의한 차이를 보였고(p<.05), 그룹 간 PS(Posture Stability) 결과는 'Med/lat'(p=.000)만으로 유의한 차이를 보였다. 이상의 결과를 종합해 보면, 균형 훈련이 비만이 있는 뇌졸중 환자의 균형 능력 및 체성분에 영향을 미치는 것으로 나타났다.

• 생약학회지
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• 제44권2호
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• pp.118-124
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• 2013

Mast cells is the key effector cells for IgE-mediated allergic responses. In this study, we investigated whether Rhus trichocarpa extract (RT) inhibited IgE-mediated allergic responses in mast cells and an allergic animal model. We further tried to find its mechanism of action in mast cells. We found that RT suppressed antigen-stimulated degranulation and production of TNF-${\alpha}$ and IL-4 in rat basophilic leukemia (RBL)-2H3 mast cells and bone marrow-derived mast cells (BMMC), as well as IgE-mediated passive cutaneous anaphylaxis (PCA) in mice. As the mechanism of action of RT, it inhibited the activation of spleen tyrosine kinase (Syk), a pivotal signaling molecule for activation of mast cells and that of LAT, a downstream adaptor molecule of Syk in $Fc{\varepsilon}RI$-mediated signal pathways. RT also suppressed the activation of mitogen-activated protein (MAP) kinases and Akt. The current results demonstrated for the first time that RT has the anti-allergic effect through inhibiting degranulation and secretion of cytokines by suppression of Syk in antigen-stimulated mast cells. Therefore, RT might be useful for allergic diseases.

• 생약학회지
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• 제50권4호
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• pp.277-284
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• 2019

Rumex crispus is known to have anticancer, antioxidant, antibacterial, and bone loss inhibitory activities. Mast cells are critical immune cells that induce a type 1 IgE-mediated allergic reaction. However, there are no reports of inhibitory effects of Rumex crispus on mast cells and allergic reactions. In this study, we performed some experiments to investigate whether Rumex crispus ethanol extract(RCE) has any inhibitory effect on antigen-induced type I allergic response in vitro and in vivo. RCE inhibited degranulation of IgE-mediated mast cells(IC₅₀, ~57 ㎍/ml) and cytokine production such as TNF-α and IL-4 in a dose-dependent manner. In vivo, RCE significantly inhibited passive cutaneous anaphylaxis(PCA)(ED₅₀, ~198 mg/kg) in mice. Furthermore, RCE inhibited degranulation of MCs in ear tissue of mice with PCA. Mechanism studies showed that RCE inhibited the activation of Syk and Syk-dependent pathway such as LAT, PLC-γ, Akt, and MAP Kinase. Our results demonstrate for the first time that RCE inhibits type I hypersensitive response by suppressing the activity of Syk in mast cells, thereby reducing degranulation and cytokine production. Taken together, RCE could be used as a novel therapeutic material to suppress allergic diseases.

• Journal of Microbiology
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• 제38권3호
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• pp.132-136
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• 2000

We recently identified Leuconostoc gelidum, a typical psychrophile, as a microbial component from kimchi that has been laboratory-prepared and fermented at 20$^{\circ}C$ . However, it has been shown that the growth of leuconostocs in food products is highly influenced by fermenting temperature. To determine the distribution of L. gelidum species in kimchi fermented at a lower temperature , 8$^{\circ}C$, we characterized a total of 64 dextran-forming strains isolated from kimchi using a polyphsic method including 16S rDNA sequencing and DNA-DNA gybridization. We found that 80% of the isolated were L. gelidum, which has been found mainly at chill-stored meat products. We also found that L. gelidum could be a dominant Leuconostoc species in so-called KimJang Kimchi, which is traditionally prepared at lat fall to be preserved during winter in Korea. These results suggest that L. gelidum can be a predominant species in kimchi especially when fermented at low temperature.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2005년도 Proceedings of ISRS 2005
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• pp.7-10
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• 2005

Plant water deficiency during drought season causes physiological stress and can be a critical indicator of forest fire vulnerability. In this study, we attempt to analyze the spectral characteristics of water stressed vegetation by using the laboratory measurement on leaf samples and the canopy reflectance spectra extracted from satellite hyperspectral image data. Leaf-level reflectance spectra were measured by varying moisture content using a portable spectro-radiometer. Canopy reflectance spectra of sample forest stands of two primary species (pine and oak) located in central part of the Korean peninsula were extracted from EO-l Hyperion imaging spectrometer data obtained during the drought season in 2001 and the normal precipitation year in 2002. The preliminary analysis on the reflectance spectra shows that the spectral characteristics of leaf samples are not compatible with the ones obtained from canopy level. Although moisture content of vegetation can be influential to the radiant flux reflected from leaf-level, it may not be very straightforward to obtain the spectral characteristics that are directly related to the level of canopy moisture content. Canopy spectra form forest stands can be varied by structural variables (such as LAt, percent coverage, and biomass) other than canopy moisture content.

• 한국농공학회논문집
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• 제59권2호
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• pp.19-27
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• 2017

Recently, the hydrological model Soil Water Assessment Tool (SWAT) has been applied in many watersheds in South Korea. This study estimated parameters in SWAT for calibrating streamflow in long-term drought periods. Therefore, we focused on the continuous severe drought periods 2014~2015, and understand the model calibrated parameters. The SWAT was applied to a $366.5km^2$ Gongdo watershed by using 14 years (2002~2015) daily observed streamflow (Q) including two years extreme drought period of 2014~2015. The 9 parameters of CN2, CANMX, ESCO, SOL_K, SLSOIL, LAT_TIME, GW_DELAY, GWQMN, ALPHA_BF were selected for model calibration. The SWAT result by focusing on 5 normal years (2002~2006) calibration showed the 14 years average Nash-Sutcliffe model efficiency (NSE) for Q and 1/Q with 0.78 and 0.58 respectively. On the other hand, the 14 years average NSEs of Q and 1/Q by focusing on 2 drought years (2014~2015) calibration were 0.86 and 0.76 respectively. Thus, we could infer that the SWAT calibration trial by focusing on drought periods data can be a good approach to calibrate both high flow and low flow by controlling the 9 drought affected parameters.

• Journal of Astronomy and Space Sciences
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• 제33권2호
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• pp.75-92
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• 2016

It is generally believed that the high energy emissions from isolated pulsars are emitted from relativistic electrons/positrons accelerated in outer magnetospheric accelerators (outergaps) via a curvature radiation mechanism, which has a simple exponential cut-off spectrum. However, many gamma-ray pulsars detected by the Fermi LAT (Large Area Telescope) cannot be fitted by simple exponential cut-off spectrum, and instead a sub-exponential is more appropriate. It is proposed that the realistic outergaps are non-stationary, and that the observed spectrum is a superposition of different stationary states that are controlled by the currents injected from the inner and outer boundaries. The Vela and Geminga pulsars have the largest fluxes among all targets observed, which allows us to carry out very detailed phase-resolved spectral analysis. We have divided the Vela and Geminga pulsars into 19 (the off pulse of Vela was not included) and 33 phase bins, respectively. We find that most phase resolved spectra still cannot be fitted by a simple exponential spectrum: in fact, a sub-exponential spectrum is necessary. We conclude that non-stationary states exist even down to the very fine phase bins.

• 한국수산과학회지
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• 제46권6호
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• pp.917-922
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• 2013

Changes in fishing ground of the large pair trawler were investigated by year, month and species off Korean waters. We used catch data by sea-block lat.${\times}$long.:$30^{\prime}{\times}30$) of the National Fisheries Research and Development Institute (NFRDI) and monthly fishing production statistics of Korean statistic information service from 1990 to 2007. In the 1990s, the demersal fish like Larimichthys polyactis, Collichthys sp, Portunus trituberculatus and Muraenesox cinereus were the dominant species, and in the 2000s, they were changed from demersal fish into pelagic fish like Scomberomorus niphonius, Scomber japonicus, Engraulis japonicus and Todarodes pacificus. Species composition of catch showed temporal variation by cluster analysis deviding into 4 period, 1990-1994, 1995-2000, 2001-2003 and 2004-2007. Fishing ground in the 2000s was decreased up to 2/3 in the 1990s, while the density of catch in the fishing ground in 2000s was higher than the 1990s.

• Journal of Astronomy and Space Sciences
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• 제30권2호
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• pp.83-85
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• 2013

Anomalous X-ray pulsars (AXPs) are thought to be magnetars which are young isolated neutron stars with extremely strong magnetic fields of > $10^{14}$ Gauss. Their tremendous magnetic fields inferred from the spin parameters provide a huge energy reservoir to power the observed X-ray emission. High-energy emission above 0.3 MeV has never been detected despite intensive search. Here, we present the possible Fermi Large Area Telescope (LAT) detection of ${\gamma}$-ray pulsations above 200 MeV from the AXP, 1E 2259+586, which puts the current theoretical models of ${\gamma}$-ray emission mechanisms of magnetars into challenge. We speculate that the high-energy ${\gamma}$-rays originate from the outer magnetosphere of the magnetar.

• Journal of Chest Surgery
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• 제24권8호
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• pp.792-796
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• 1991

Immature teratoma can be viewed as intermediate between mature teratoma and embryonal carcinoma. Unlike the mature teratoma, elements of the three perm cell layers are incompletely differentiated and not arranged in organoid fashion In some area, more mature forms of these tissues may also be seen, Although this tumor is clearly malignant, they may not display clear-cut cytologic features of malignancy. The clinical prognosis is poor. We have experienced one case of recurrent immature teratoma. In first operation[1987, April], tumor of anterior mediastinum was removed with wedge resection of ant. segment of RUL % med. segment of RML. In 2nd operation[1990, June], recurrent teratoma of right inner thoracic wall was resected with partial 5th rib resection and wedge resection of lat. segment of middle lobe. Two months later, the 3rd operation[1990, September] was done, which was a removal of mass on thoracic wall near sup, segment of RLL and partial rib resection of 3rd, 4th & 5th. In November 1990, last operation[4th operation] was made. It was enucleation of walnut sized tumor located between medial segment of RML, and 4th. intercostal space, well encapsulated with endothoracic fascia and invaded into lung parenchyme, Adjuvant chemotherapy was done after each operation, but radiotherapy[5000 Rad] was done only after 1st operation. There was no evidence of recurrence after last operation. The patient is well-being still now.