• Title/Summary/Keyword: LAM-B

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Influence of Chongcao Yigan Capsule on Function of Intestinal Flora and Chemoprevention for Patients with Chronic Hepatitis B-Induced Liver Fibrosis

  • Zhao, Xiao-Hu;Cao, Zheng-Yu;Shen, Yang;Lv, Yu-Feng;Tao, Guang-Rong;Chen, Sheng
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.21
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    • pp.9423-9426
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    • 2014
  • Objective: Hapatitis B visus (CHB)-induced fibrosis is a precancerous condition of liver. To explore the influence of Chongcao Preparation (Chongcao Yigan Capsule) on the function of intestinal flora and chemoprevention for patients with CHB-induced liver fibrosis. Methods: A total of 136 patients with CHB-induced liver fibrosis were randomly divided into control group treated with lamivudine (LAM) and research group added with Chongcao Yigan Capsule for totally 48 weeks. The changes of intestinal flora, secretory immunoglobin A (SIgA), serum albumin (ALB), prealbumin (PALB), IgA and IgG at different time points in both groups were observed. Results: Before treatment, there was no significant difference between two groups in each index (P>0.05). After treatment, the intestinal flora were evidently optimized in research group than treatment before (P<0.05 or P<0.01), and were apparently better than those in control group (P<0.05 or P<0.01); SIgA was obviously increased and ALB, PALB, IgA and IgG were markedly improved in research group than treatment before (P<0.05 or P<0.01), and were significantly better than those in control group (P<0.05 or P<0.01). Conclusions: Chongcao Yigan Capsule could regulate the intestinal flora, increase SIgA, serum ALB and PALB concentrations and significantly improve serum IgA and IgG as well as strengthen the immunological function and autologous repair capacity of patients with CHB-induced liver fibrosis.

Design and Implementation of an Automatic Switching Technology Between Ad-Hoc and Infrastructure Modes in Wireless LANs (무선 LAN에서 Ad-Hoc과 Infrastructure 모드의 자동전환 기술 설계 및 구현)

  • Shin Taek-Su;Jo Sung-Min;Min Sang-Won
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.31 no.9A
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    • pp.892-899
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    • 2006
  • In this paper, we propose an automatic switching technology between the ad-hoc and the infrastructure modes without user intervention in the IEEE 802.11b wireless LAN. Also, we design our proposed technology and implemented on the Linux machine. For this operation, the area within an Access Point (AP) coverage is defined as a switching area, and a node without any transmission in this area is assumed to be able to relay frames between the AP and nodes in the shaded area that is outside the coverage and cannot reach the AP. By using the proposed technology, it is possible to provide the seamless Internet access service to nodes at the ad-hoc mode in the shaded area. In this paper, we explains the operation of the detection method of the switching area, presents the flowchart and implementation environment. To prove the operation of our technology, we obtain the results of captured packets transmitted between nodes and throughput results through ftp transmission experiment. Hence, we can see that our proposed scheme can be improve the wireless access service in wireless and mobile networks.

Salt-induced Differential Gene Expression in Italian Ryegrass (Lolium multiflorum Lam.) Revealed by Annealing Control Primer Based GeneFishing approach

  • Lee, Ki-Won;Lee, Sang-Hoon;Choi, Gi Jun;Ji, Hee Jung;Hwang, Tae Young;Kim, Won Ho;Rahman, Md. Atikur
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.37 no.3
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    • pp.231-236
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    • 2017
  • Salt stress is one of the most limiting factors that reduce plant growth, development and yield. However, identification of salt-inducible genes is an initial step for understanding the adaptive response of plants to salt stress. In this study, we used an annealing control primer (ACP) based GeneFishing technique to identify differentially expressed genes (DEGs) in Italian ryegrass seedlings under salt stress. Ten-day-old seedlings were exposed to 100 mM NaCl for 6 h. Using 60 ACPs, a total 8 up-regulated genes were identified and sequenced. We identified several promising genes encoding alpha-glactosidase b, light harvesting chlorophyll a/b binding protein, metallothionein-like protein 3B-like, translation factor SUI, translation initiation factor eIF1, glyceraldehyde-3-phosphate dehydrogenase 2 and elongation factor 1-alpha. These genes were mostly involved in plant development, signaling, ROS detoxification and salt acclimation. However, this study provides new molecular information of several genes to understand the salt stress response. These genes would be useful for the enhancement of salt stress tolerance in plants.

Interspecific Transferability of Watermelon EST-SSRs Assessed by Genetic Relationship Analysis of Cucurbitaceous Crops (박과작물의 유연관계 분석을 통한 수박 EST-SSR 마커의 종간 적용성 검정)

  • Kim, Hyeogjun;Yeo, Sang-Seok;Han, Dong-Yeop;Park, Young-Hoon
    • Horticultural Science & Technology
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    • v.33 no.1
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    • pp.93-105
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    • 2015
  • This study was performed to analyze genetic relationships of the four major cucurbitaceous crops including watermelon, melon, cucumber, and squash/pumpkin. Among 120 EST-SSR primer sets selected from the International Cucurbit Genomics Initiative (ICuGI) database, PCR was successful for 51 (49.17%) primer sets and 49 (40.8%) primer sets showed polymorphisms among eight Cucurbitaceae accessions. A total of 382 allele-specific PCR bands were produced by 49 EST-SSR primers from 24 Cucurbitaceae accessions and used for analysis of pairwise similarity and dendrogram construction. Assessment of the genetic relationships resulted in similarity indexes ranging from 0.01 to 0.85. In the dendrogram, 24 Cucurbitaceae accessions were classified into two major groups (Clade I and II) and 8 subgroups. Clade I comprised two subgroups, Clade I-1 for watermelon accessions [I-1a and I-1b-2: three wild-type watermelons (Citrullus lanatus var. citroides Mats. & Nakai), I-1b-1: six watermelon cultivars (Citrullus lanatus var. vulgaris S chrad.)] a nd C lade I -2 for melon and cucumber accessions [I-2a-1 : 4 melon cultivars(Cucumis melo var. cantalupensis Naudin.), I-2a-2: oriental melon cultivars (Cucumis melo var. conomon Makino.), and I-2b: five cucumber cultivars (Cucumis sativus L.)]. Squash and pumpkin accessions composed Clade II {II-1: two squash/ pumpkin cultivars [Cucurbita moschata (Duch. ex Lam.)/Duch. & Poir. and Cucurbita maxima Duch.] and II-2: two squash/pumpkin cultivars, Cucurbita pepo L./Cucurbita ficifolia Bouche.}. These results were in accordance with previously reported classification of Cucurbitaceae species, indicating that watermelon EST-SSRs show a high level of marker transferability and should be useful for genetic study in other cucurbit crops.

Anti-Diabetic, Alcohol-Metabolizing, and Hepatoprotective Activities of Moringa (Moringa oleifera Lam.) Leaf Extracts (모링가 잎 추출물의 항당뇨, 알코올 대사 및 간 보호 활성)

  • Choi, Young Ju;Jung, Kyung Im
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.45 no.6
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    • pp.819-827
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    • 2016
  • This study was carried out to investigate anti-inflammatory, anti-diabetic, alcohol metabolizing, and hepatoprotective effects of hot water (MOW) and 80% ethanol (MOE) extracts from moringa (Moringa oleifera Lam.) leaf. The total phenol content of MOW and MOE were 45.49 and 63.06 mg tannic acid equivalents/g, respectively. 1,1-Diphenyl-2-picrylhydrazyl radical scavenging activities of MOW and MOE were remarkably elevated in a dose-dependent manner, and about 60.8% and 71.3% at 1 mg/mL, respectively (P<0.01). Superoxide dismutase-like activities of MOW and MOE were 2.8% and 7.4% at 5 mg/mL, respectively (P<0.05). ${\alpha}-Glucosidase$ inhibitory activity also increased in a dose-dependent manner in both extracts, and MOE was higher about two times than MOW at 5 mg/mL (P<0.001). The effects of MOW and MOE on alcohol metabolizing activity were determined by measuring generation of reduced nicotinamide adenine dinucleotide (NADH) by alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH). ADH and ALDH activities significantly increased upon addition of MOW and MOE (P<0.05). Anti-inflammatory activity was examined in lipopolysaccharide-stimulated RAW 264.7 cells. Nitric oxide production was reduced to 32.1% and 81.2% by addition of MOW and MOE at 1 mg/mL, respectively (P<0.05). MOW and MOE showed significant protective effects against tacrine-induced cytotoxicity in Hep3B cells at $100{\mu}g/mL$. These results suggest that moringa leaf extracts have great potential as natural health products.

Design and Fabrication of Miniaturized Dual-bandpass filter Using Rectangular ring resonator and Interdigital capacitive feeding-structure (Rectangular Ring 공진기와 Interdigital Capacitive 급전구조를 이용한 소형화된 이중대역통과필터의 설계 및 제작)

  • Yoon, Hyun-Soo;Kang, Sang-Rok;Choi, Byoung-Ha
    • Journal of Navigation and Port Research
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    • v.31 no.5 s.121
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    • pp.415-420
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    • 2007
  • In this paper, we have designed and fabricated a new type of bandpass-filter that used rectangular ring and interdigital capacitive feeding-structure. The filter is applied the modified rectangular ring and interdigital capacitive feeding-structure in patch, which reduce rho size of filter and IEEE 802. 11 correspond to wireless LAN domain(2.45GHz and 5.2GHz) for operating. As a result, the design and fabrication process of the filter become simple and the size of it is reduced more than 60% compared with RF filter are available conventional PEMBF(Parallel Edge-coupled Microstrip Bandpass Filter) of accounted circuit by minimum stage, measurement result of fabricated filter, center frequence is down 2.408GHz and 5.075GHz. input return loss is -39.169dB at 2.408GHz, -40.922dB at 5.075GHz. insertion loss is -0.437dB at 2.408GHz, -1.669dB at 5.075GHz.

Chemical Investigations and Anti-inflammatory Activity of Fixed Oil of Butea monosperma Seeds

  • Gunakunru, A.;Padmanaban, K.;Thirumal, P.;Vengatesan, N.;Gnanasekar, N.;Raja, S.;Rajarajan, A.T.;Kumar, S. G. Vijaya;Perianayagam, J. Britto
    • Natural Product Sciences
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    • v.10 no.2
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    • pp.55-58
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    • 2004
  • The fruit and seeds of Butea monosperma (Lam) Kuntze (Fabaceae) are useful in piles, anthelmintic, eye diseases, and inflammation in the Indian system of medicine. Hence, we have evaluated the anti-inflammatory activity of the fixed oil, mixed fatty acids, and unsaponifiable matter of B. monosperma against carrageenan-induced paw oedema and cotton pellet-induced granuloma in rats. The fixed oil, mixed fatty acids, and unsaponifiable matter of the oil exhibited significant anti-inflammatory activity on the tested experimental animal models. The unsaponifiable matter of the oil produced higher protection compared to fixed oil and mixed fatty acids. Phytochemical analysis of the fixed oil revealed the presence of steroids and terpenoids while unsaponifiable matter of the oil showed the presence of ${\beta}-sitosterol$. Also, four fatty acids were identified in the fixed oil by gas liquid chromatography. The anti-inflammatory activity of the fixed oil may be due to unsaponifiable matter or combination of unsaponifiable matter and mixed fatty acids.

Effects of cyclic loading on the long-term deflection of prestressed concrete beams

  • Zhang, Lihai;Mendis, Priyan;Hon, Wong Chon;Fragomeni, Sam;Lam, Nelson;Song, Yilun
    • Computers and Concrete
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    • v.12 no.6
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    • pp.739-754
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    • 2013
  • Creep and shrinkage have pronounced effects on the long-term deflection of prestressed concrete members. Under repeated loading, the rate of creep in prestressed concrete members is often accelerated. In this paper, an iterative computational procedure based on the well known Model B3 for creep and shrinkage was developed to predict the time-dependent deflection of partially prestressed concrete members. The developed model was validated using the experimental observed deflection behavior of a simply supported partially prestressed concrete beam under repeated loading. The validated model was then employed to make predictions of the long-term deflection of the prestressed beams under a variety of conditions (e.g., water cement ratio, relatively humidity and time at drying). The simulation results demonstrate that ignoring creep and shrinkage could lead to significant underestimation of the long-term deflection of a prestressed concrete member. The model will prove useful in reducing the long-term deflection of the prestressed concrete members via the optimal selection of a concrete mix and prestressing forces.

Ruminal Solubility of Trace Elements from Selected Philippine Forages

  • Serra, S.D.;Serra, A.B.;Ichinohe, T.;Fujihara, T.
    • Asian-Australasian Journal of Animal Sciences
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    • v.10 no.4
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    • pp.378-384
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    • 1997
  • The ruminal solubility of copper (Cu), manganese (Mn), molybdenum (Mo), and zinc (Zn) in eight Philippine forages was studied. These forages were: 1) grasses: paragrass (Brachiaria mutica (Forsk.) Stapf), stargrass (Cynodon plectostachyum Pilger), and napiergrass (Pennisetum purpureum Schumach.); 2) creeping legumes: calopogonium or calopo (Calopogonium muconoides Desv.) and centrocema (Centrocema pubescens Benth.); 3) tree lequmes: gliricidia or kakawate (Gliricidia sepium (Jacq.) Walp.), leucaena or ipil-ipil (Leucaena leucocephala (Lam.) de Wit.), and sesbania or katuray (Sesbania grandiflora (L.) Poir). Nylon bags with samples were incubated for 0, 3, 6, 12, 24, 48 and 72h in three rumen cannulated sheep fed with timothy hay (Phleum pratense L.) at 2% body weight/d. The 0-h bags were washed with deionized water. There were species differences (p < 0.05) on the different solubilities of trace elements. At O-h incubation, the trend of solubility was Mo (54%) > Zn (43%) > Cu (38.7%) > Mn (29.5%). At 3-h incubation, all the elements except Mn had an average solubility above 50%. Combining particulate passage rate (1.9%/h) and various trace elements disappearance rates, the effective ruminal solubilization (ERS) of trace elements were computed. The ERS across species ranged from 44.6 to 89.9% for Cu, 29.9 to 84% for Mn, 66 to 95.1% for Mo, and 30.1 to 82.3% for Zn resulting to a trend of Mo > Zn > Cu > Mn.

Logical Link-Based Multicasting Services in Ethernet Passive Optical Networks (이더넷 수동형 광가입자망에서 논리적 링크 기반의 멀티캐스팅 서비스)

  • Choi Su-il
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.11B
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    • pp.722-729
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    • 2005
  • Ethernet passive optical networks (EPONs) are an emerging access network technology which has a point-to-multipoint topology. EPONs operate point-to-multipoint in the OLT-ONU direction, and point-to-point in the ONU-OLT direction. To support point-to-point emulation and shared LAM emulation, EPONs use multi-point control protocol (MPCP). The MPCP uses logical link identification (LLID) field for frame tagging and filtering between the OLT and ONUs. In this paper, I propose logical-group identification (LGID) for logical link-based multicasting or VLAN services in EPONs. Using LGID with new frame tagging and filtering rules, EPONs support differentiated multimedia broadcasting or multicasting services. Additionally, EPONs can support logical link-based VLAN services that divides ONUs into several subsets.