• Title/Summary/Keyword: L$^{p}$ estimates

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Antimicrobial Efficacy of Penicillium amestolkiae elv609 Extract Treated Cotton Fabric for Diabetic Wound Care

  • Rozman, Nur Amiera Syuhada Binti;Hamin, Nurhanis Syafiqah Binti Mohd Nor;Ring, Leong Chean;Nee, Tan Wen;Mustapha, Mahfuzah Binti;Yenn, Tong Woei
    • Mycobiology
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    • v.45 no.3
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    • pp.178-183
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    • 2017
  • Diabetes mellitus is a chronic disorder which affects millions of population worldwide. Global estimates published in 2010 reported the world diabetic prevalence as 6.4%, affecting 285 million adults. Foot ulceration and wound infection are major forms of disabilities arising from diabetic diseases. This study was aimed to develop a natural antimicrobial finishing on medical grade textile that meets American Association of Textiles Chemists and Colorists (AATCC) standard. The textile samples were finished with the ethanolic extract of Penicillium amestolkiae elv609, an endophytic fungus isolated from Orthosiphon stamineus Benth (common name: cat's whiskers). Endophyte is defined as microorganism that reside in the living plant tissue, without causing apparent disease symptom to the host. The antimicrobial efficacy of the ethanolic extract of P. minioluteum was tested on clinical pathogens isolated from diabetic wound. The extract exhibited significant inhibitory activity against 4 bacteria and 1 yeast with the minimal inhibitory concentration ranged from 6.25 to 12.5 mg/mL. The results indicate different susceptibility levels of the test microorganism to the ethanolic extract. However, the killing activity of the extract was concentration-dependent. The finished medical textile showed excellent antimicrobial efficacy on AATCC test assays. All the microbial cultures treated with the textile sample displayed a growth reduction of 99.9% on Hoheinstein Challenge Test. The wash durability of the finished textile was found good even after 50 washes with commercial detergent. Besides, the gas chromatography mass spectrometry analysis showed that 6-octadecenoic acid and diethyl phthalate were the main bioactive constituents of the extract. In conclusion, the developed medical textile showed good antimicrobial efficacy on laboratory tests. This work can be extended to in vivo trials for developing healthcare textile products for antimicrobial applications.

Cumulative live birth rate after up to three consecutive embryo transfer cycles in women with poor ovarian response

  • Kim, Se Jeong;Lee, Dayong;Kim, Seul Ki;Jee, Byung Chul;Kim, Seok Hyun
    • Clinical and Experimental Reproductive Medicine
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    • v.47 no.2
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    • pp.135-139
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    • 2020
  • Objective: In the present study, we aimed to retrospectively evaluate the cumulative live birth rate (LBR) after up to three consecutive embryo transfer (ET) cycles, either fresh or frozen, in women with expected poor ovarian response (ePOR). Methods: We selected 115 women who entered the first in vitro fertilization (IVF) cycle between August 2013 and July 2016. The women were divided into an ePOR group (37 women) and a non-ePOR group (78 women). All women in the ePOR group were ≥ 40 years old or had serum anti-Müllerian hormone levels of less than 1.1 ng/mL at the time of the first IVF cycle. Live birth outcomes were monitored until December 2017. The cumulative LBR (with both conservative and optimistic estimates) was calculated according to the serial number of ET cycles. Results: After up to three ET cycles, the overall cumulative LBR was significantly lower in the ePOR group than in the non-ePOR group (conservative estimate, 10.8% vs. 44.9%, respectively; optimistic estimate, 14.7% vs. 56.1%, respectively; log-rank test, p= 0.003). Conclusion: Women with ePOR exhibited a lower cumulative LBR than women in the non-ePOR group, and this information should be provided to ePOR women during counseling before starting IVF.

Measurement of Effective Half-life Using Dual Time I-131 Whole Body Scan in Patients with Differentiated Thyroid Cancer Treated by High Dose Therapy (고용량 방사성옥소 치료를 받은 갑상선분화암 환자에서 Dual Time I-131 Whole Body Scan을 이용한 유효반감기의 측정)

  • Yoon, Jae Sik;Lee, Jae Gon;Lee, Ki Hyun;Lim, Kwang Seok;Choi, Hak Ki;Lee, Sang Mi
    • The Korean Journal of Nuclear Medicine Technology
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    • v.18 no.1
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    • pp.98-103
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    • 2014
  • Purpose: The effective half life of I-131 is useful to calculate radiation dose, period of hospitalization, and exposure dose of surrounding people from patient. However, it is difficult to measure. This study estimates the effective half life in whole body and thyroid in using of value of residual radioactivity obtained from the early and delay images of Dual time I-131 whole body scan. Also, the correlations between the effective half life and serum creatinine, GFR, and administration dose were investigated in this study. Materials and Methods: The targets were 50 patients administration high dose of I-131 from February to August in 2013, having normal range of serum creatinine and over $30{\mu}IU/mL$ of TSH levels. After administration radioactive I-131, the early scan in the 3rd day and the delay scan in the 5-6th days were performed. To measure the residual radioactivity in the whole body and thyroid, ROI was set and then background radioactivity was corrected to estimate. The effective half life was estimated by calculating the ratio of measured values between the early and delay images. To compare the effective half lives of the whole body and thyroid, it was analyzed by Independent t-test, and each correlation of the effective half life, GFR, serum creatinine, and the dose of administration were analyzed by calculating the pearson's correlation coefficient. All of the analysis were determined to be statistically significant when P<0.05. Results: The effective half life of the whole body was $17.06{\pm}5.50$ hours and of the thyroid was $17.22{\pm}5.41$ hours. The two effective half life did not show significant difference (P=0.887). As the value of GFR was increased, the effective half life of whole body (r=-0.407, P=0.003) and of thyroid (r=-0.473, P=0.001) were significantly decreased; as the value of serum creatinine was increased, the effective half life of whole body (r=0.309, P=0.029) and of thyroid (r=0.371, P=0.008) were significantly increased. In the administration dose, effective half life did not have correlations. Conclusion: The effective half life of I-131 of patients treated for their thyroids were estimated only by using the images of Dual time I-131 whole body scan. Also, the correlations with the effective life, GFR, and serum creatinine were examined. This study might be utilized for a study on optimization for the period of hospitalization of patients treated by high dose of I-131 and on evaluation for internal absorbed dose of MIRD schema in application of the effective half life.

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Use of N-alkanes to Estimate Intake and Digestibility by Beef Steers

  • Premaratne, S.;Fontenot, J.P.;Shanklin, R.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.11
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    • pp.1564-1568
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    • 2005
  • The objective of the study was to evaluate the use of n-alkanes to estimate DM intake and digestibility by beef cattle. Six steers were blocked (3 blocks, 2 animals/block) according to the body weight (279${\pm}$19 kg) and randomly allotted within blocks to two diets (3 steers/diet). A second trial was conducted with the same animals (321${\pm}$18 kg) after 36 days (d), using a switch back design. The diets consisted of two types of chopped sun-cured hay, alfalfa (Medicago sativa L) hay, or fescue (Festuca arundinacea Schreb) and alfalfa mixture, which were fed in equal amounts to steers. Animals were dosed with $C_{32}$ and $C_{36}$ alkanes, employing an intra-ruminal controlled-release device at the beginning of each trial. Hay intake per animal was measured from d 6 to 12 and sub samples were taken for chemical analysis. Rectal samples of feces were taken from each animal once/daily from d 8 to 14, freeze dried, and ground prior to alkane analysis. Alkanes were extracted from ground hay and feces. Feed intake was calculated from the dose rate of $C_{32}$ alkane and, the herbage and fecal concentrations of adjacent odd ($C_{33}$ or $C_{31}$) and even ($C_{32}$) chain length alkanes. Crude Protein, NDF, ADF, ash concentrations and In vitro dry matter digestibility (IVDMD) were 17.7, 42.2, 28.4, 7.9 and 71.7 for alfalfa, and 12.4, 56.5, 30.4, 6.9 and 69.1% for fescue/alfalfa mixture, respectively. For both diets, intake estimated from $C_{33}$:$C_{32}$ ratio was not different from the measured intake, but intake estimated from $C_{31}$:$C_{32}$ ratio was lower (p<0.05), than the measured intake for both diets. The average estimated forage intake from $C_{33}$:$C_{32}$ ratio was 4.86 and 0.69% below than the measured intake for alfalfa and, fescue/alfalfa mixed diets, respectively. The respective estimates with $C_{31}$:$C_{32}$ ratio were 9.59 and 11.33% below than the measured intake. According to these results, alkane $C_{33}$:$C_{32}$ ratio is better than alkane $C_{31}$:$C_{32}$ ratio for the estimation of intake by beef steers.

A Structural Model for Health Promotion and Life Satisfaction of Life in College Students in Korea (대학생들의 건강증진행위와 삶의 만족도에 대한 구조모형)

  • Hong, Youn-Lan;Yi, Ga-Eon;Park, Hyun-Sook
    • Research in Community and Public Health Nursing
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    • v.11 no.2
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    • pp.333-346
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    • 2000
  • The purpose of this study was designed to test and develope the structural model that explains health promoting behaviors among college students in Korea. The hypothetical model was constructed on the Pender's Health promotion Model(l996) and the inclusion of some influential factors for life satisfaction. The conceptual framework was built around eight constructs. Exogenous variables included in the model were self-esteem, perceived health status, self-efficacy, internal locus of control, chance locus of control. powerful other locus of control. Endogenous variables were health promotion behaviors and life satisfaction. The results are as follows; 1. The overall fit of the hypothetical model to the data was moderate <$x^2$=4.18(df=11. p=0.041), GFI= 0.99, AGFI= 0.76, RMR= 0.019, CFI= 0.99, CN= 248.50> 2. Path and variable of the model were modified by considering both its theoretical implication and statistical significance of parameter estimates. Compared to the hypothetical model. the revised model has become parsimonious and had a better fit to the data expected in a chi-square value <$x^2$=8.43( df= 16, p=0.21), GFI= 0.99, AGFI= 0.92., RMR= 0.024, CFI= 0.99, CN= 312.01> 3. Some of the predictive factors. especially self efficacy. self esteem. powerful others locus of control. perceived health status revealed the direct effects on health promoting behaviors. Of these variables. self-efficacy was the most signigicant factor. These predictive variables of health promoting behaviors explained 59% of total variances in the model. 4. Health promoting behaviors, self-esteem. and perceived health status revealed direct effect on the life satisfaction. Self-efficacy was identified as an important variable that contributed indirectly to improve life satisfaction by enhancing health promoting behaviors. These predictive variables of life satisfaction explained 42% of total variances in the model. In conclusion. the derived model in this study is considered appropriate in explaining and predicting health promoting models and life satisfaction among college students in Korea and could effectively be used as a reference model for further studies by suggesting a direction in health promoting nursing practices.

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New Estimates of CH4 Emission Scaling Factors by Amount of Rice Straw Applied from Korea Paddy Fields (볏짚 시용에 따른 벼 재배 논에서의 메탄 배출계수 개발에 관한 연구)

  • Ju, Okjung;Won, Tae-Jin;Cho, Kwang-Rae;Choi, Byoung-Rourl;Seo, Jae-Sun;Park, In-Tae;Kim, Gun-Yeob
    • Korean Journal of Environmental Agriculture
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    • v.32 no.3
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    • pp.179-184
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    • 2013
  • BACKGROUND: Accurate estimates of total direct $CH_4$ emissions from croplands on a country scale are important for global budgets of anthropogenic sources of $CH_4$ emissions and for the development of effective mitigation strategies. Methane production resulted by the anaerobic decomposition of organic compounds where $CO_2$ acts as inorganic electron acceptor. This process could be affected by the addition of rice straw, water management and rice variety itself. METHODS AND RESULTS: Rice (Oryza sativa L. Japonica type, var Samkwangbyeo) was cultivated in four plots: (1) Nitrogen-Phosphorus-Potassium (NPK) ($N-P_2O_5-K_2O$:90-45-57 kg/ha); (2) NPK plus 3 Mg/ha rice straw (RS3); (3) NPK plus 5 Mg/ha rice straw (RS5); (4) NPK plus 7 Mg/ha rice straw (RS7) for 3 years (2010-2012) and the rice straw incorporated in fall (Nov.) in Gyeonggi-do Hwaseong-si. Gas samples were collected using the closed static chamber which were installed in each treated plot of $152.9m^2$. According to application of 3, 5, 7 Mg/ha of rice straw, methane emission increased by 46, 101, 190%, respectively, compared to that of the NPK plot. CONCLUSION(S): We obtained a quantitative relationship between $CH_4$ emission and the amount of rice straw applied from rice fields which could be described by polynomial regression of order 2. The emission scaling factor estimated by the relationship were in the range of IPCC GPG (2000).

The Comparison of Glomerular Filteration Rate by Kidney Depth in Dynamic kidney Scan (동적신장검사에서 신장깊이에 따른 사구체여과율 비교)

  • Hwang, Ju-Won;Lim, Young-Hyen;Yun, Jong-Jun;Lee, Hwa-Jin;Lee, Mu-Seok;Jung, Ji-Uk;Park, Se-Yun
    • The Korean Journal of Nuclear Medicine Technology
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    • v.18 no.2
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    • pp.73-77
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    • 2014
  • Purpose Find out about the significance of the GFR values calculated by the kidney depth is measured by comparing the values obtained for kidney depth was measured GFR in the CT image kidney depth and is calculated by Tonnesen law in $^{99m}Tc$-DTPA dynamic kidney scan with each applies. Materials and Methods Among patients with normal value (75~120 mL/min) computed GFR conducted of dynamic renal scan to visit from February 2013 to February 2014 and donor GFR values in patients with normal value. The mean age was 46.9 years with 14 men 13 females. We used abdomen CT image which checked before conducting dynamic Kidney scan for measuring the depth of kidney. We only used CT image that contains renal hilum and measured outermost front of the kidney from the skin surface (a) and the final surface (b) caculated the average depth of [(a + b) / 2] respectively. Using the same ROI in order to limit the change in GFR values by the other additional element was set before and after the depth value was excluded from the GFR falls kidney disease. Results Using Tonnesen law the average value was caculated 5.94 cm from the right kidney 5.90 cm from the left kidney. It was 6.83 cm, 8.71 cm in the left kidney and the right kidney average value of the depth measured on the basis of the CT image. The respective increase in left kidney 0.93 cm and right kidney 2.77 cm calculated on the basis of CT image actually measured values. GFR was calculated as the average depth of the subject calculated by the method Tonnesen $83.3{\pm}9.79mL/min$. $98.6{\pm}14.07mL/min$ GFR was applied to calculate the average depth of the subjects using the CT image, is the difference appears 15.26 mL/min was increased after seting up depth value, P value was less than 0.01 which is significant. Conclusion The difference between GFR before-after setting up depth value cause that the different of depth value. Is a measured depth of the extension value of the calculated estimates Whereas Tonnesen kidney depth method is to use in calculating the value of GFR in a typical dynamic elongation test depth derived using the CT image depth. Is thought to be able to calculate more accurately the GFR value by the distance to the center of kidney more accurately measured in the skin thereby.

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Estimation on Population Ecological Characteristics of Crucian Carp, Carassius auratus in the Mid-Upper System of the Seomjin River (섬진강 중.상류 수계에서 붕어 개체군의 생태학적 특성치 추정)

  • Jang, Sung-Hyun;Ryu, Hui-Seong;Lee, Jung-Ho
    • Korean Journal of Environment and Ecology
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    • v.25 no.3
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    • pp.318-326
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    • 2011
  • The population ecological characteristics of the Crucian carp, Carassius auratus, were determined in order to estimate stock of the mid-upper system of the Seomjin River. The fish ranged in size from 95 to 288mm total length. The age was determined by counting the scale annulus. The scales displayed clear annulus that were used to estimate the age. The oldest fish observed in this study was 5 years old. Age-2 fishes were the most numerous in the sample(n=38), followed in frequency be age-3(n=22). Marginal index analysis validated the formation of a single annulus per year. The relationship between body length and body weight was BW = $0.0038BL^{3.73}$($R^2$=0.96) (p<0.01). The relationship between the scale radius and body length was BL = 2.362R+2.76($R^2$=0.89). The von Bertalanffy growth parameters estimated from a non-linear regression method were $L_{\infty}$=33.2 cm, $W_{\infty}$=1,798.4 g, $K=0.20year^{-1}$ and $t_0$=-0.51year. Therefore, Growth in length of the fish was expressed by the von Bertalanffy's growth equation as $L_t=33.23$($1-e^{-0.20(t+0.51)}$)($R^2$=0.98). The annual survival rate was estimated to be 0.427year$^{-1}$. The instantaneous coefficient of natural mortality of estimated from the Zhang and Megrey method was $0.784year^{-1}$, and instantaneous coefficient of fishing mortality was calculated $0.067year^{-1}$. From the estimates of survival rate, the instantaneous coefficient of total mortality was estimated to be $0.851year^{-1}$.

A Study on the Stock Assessment and Management Implications of the Korean Aucha perch (Coreoperca herzi) in Freshwater: (1) Estimation of Population Ecological Characteristics of Coreoperca herzi in the Mid-Upper System of the Seomjin River (담수산 어류 꺽지 (Coreoperca herzi)의 자원 평가 및 관리 방안 연구: 섬진강 중.상류 수계에서 꺽지의 개체군 생태학적 특성치 추정 (1))

  • Jang, Sung-Hyun;Ryu, Hui-Seong;Lee, Jung-Ho
    • Korean Journal of Ecology and Environment
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    • v.43 no.1
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    • pp.82-90
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    • 2010
  • The ecological characteristics of the Korean Aucha perch, Coreoperca herzi, were determined in order to estimate stock of the mid-upper system of the Seomjin River. The age was determined by counting the otolith annuli. The oldest fish observed in this study was 5 years old. Relationships between body length (BL) and body weight (BW) were $BW=0.0195BL^{3.08}$ ($R^2=0.966$) (p<0.01). Relationships between the otolith radius (R) and body length (BL) were BL=3.882R+1.66 ($R^2=0.944$). The von Bertalanffy growth parameters estimated from a non-linear regression method were $L_{\infty}=19.68\;cm$, $W_{\infty}=188.64\;g$, $K=0.17\;year^{-1}$ and $t_0=-1.46$ year. Therefore, growth in length of the fish was expressed by the von Bertalanffy's growth equation as $L_t=19.68$ ($1-e^{-0.17(t+1.46)}$) ($R^2=0.997$). The annual survival rate (S) was estimated to be $0.666\;year^{-1}$. The instantaneous coefficient of natural mortality (M) of estimated from the Zhang and Megrey method was $0.346\;year^{-1}$, and instantaneous coefficient of fishing mortality (F) was calculated $0.061\;year^{-1}$. From the estimates of survival rate (S), the instantaneous coefficient of total mortality(Z) was estimated to be $0.407\;year^{-1}$.

Regional Distribution of Peach Freezing Damage and Chilling Days in 2010 in Gangwon Province (강원지역의 2010년 복숭아 동해)

  • Seo, Young-Ho;Park, Young-Sik;Cho, Byoung-Ouk;Kang, An-Seok;Jeong, Byeong-Chan;Jung, Yeong-Sang
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.12 no.4
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    • pp.225-231
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    • 2010
  • Extremely low values of the daily minimum temperature occurred in January 2010, ranging from -18 to $-29^{\circ}C$ at various locations growing peach trees in the Gangwon province. Due to the extreme cold temperature during the winter dormancy period of peach trees, the growth of the peach trees was damaged and the damaged areas increased as the extent of 17 to 144 ha. In order to provide information on mitigation measure of the cold temperature on the peach trees in the Gangwon province, we assessed the distribution of the damaged areas of growing the peach trees in 2010 and compared it with freezing risk estimated from the dormancy depth of the peach trees and the daily minimum temperature. The dormancy depth of 'Changhowon Hwando (Prunus persica (L.) Batsch)' ranged from -62 to -90 and the freezing risk was greater than 51%. The relationship between the freezing risk and the actual damaged area ratio showed reasonable agreement ($r^2$ of 0.5 with p < 0.01). The results imply that the estimates of the freezing risk based on the dormancy depth can be used as a mitigation measure to identify susceptible peach growing areas to freezing damage injury.