• Korean Journal of Radiology
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• 제23권6호
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• pp.664-673
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• 2022

Objective: To evaluate the performance of baseline clinical characteristics and pretherapeutic histogram parameters derived from T2 mapping of the extraocular muscles (EOMs) in the prediction of treatment response to intravenous glucocorticoid (IVGC) therapy for active and moderate-to-severe thyroid-associated ophthalmopathy (TAO) and to investigate the effect of fat-suppression (FS) in T2 mapping in this prediction. Materials and Methods: A total of 79 patients clinically diagnosed with active, moderate-to-severe TAO (47 female, 32 male; mean age ± standard deviation, 46.1 ± 10 years), including 43 patients with a total of 86 orbits in the responsive group and 36 patients with a total of 72 orbits in the unresponsive group, were enrolled. Baseline clinical characteristics and pretherapeutic histogram parameters derived from T2 mapping with FS (i.e., FS T2 mapping) or without FS (i.e., conventional T2 mapping) of EOMs were compared between the two groups. Independent predictors of treatment response to IVGC were identified using multivariable analysis. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the predictive performance of the prediction models. Differences between the models were examined using the DeLong test. Results: Compared to the unresponsive group, the responsive group had a shorter disease duration, lower kurtosis (FS-kurtosis), lower standard deviation, larger 75th, 90th, and 95th (FS-95th) T2 relaxation times in FS mapping and lower kurtosis in conventional T2 mapping. Multivariable analysis revealed that disease duration, FS-95th percentile, and FS-kurtosis were independent predictors of treatment response. The combined model, integrating all identified predictors, had an optimized area under the ROC curve of 0.797, 88.4% sensitivity, and 62.5% specificity, which were significantly superior to those of the imaging model (p = 0.013). Conclusion: An integrated combination of disease duration, FS-95th percentile, and FS-kurtosis was a potential predictor of treatment response to IVGC in patients with active and moderate-to-severe TAO. FS T2 mapping was superior to conventional T2 mapping in terms of prediction.

• Restorative Dentistry and Endodontics
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• 제38권1호
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• pp.52-54
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• 2013

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2002년도 하계학술대회 논문집 Vol.3 No.2
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• pp.927-930
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• 2002

The HFPD measurement method is a technique to analyze aging state of high voltage insulation materials and detect higher frequency signals than conventional PD measurement method therefore it takes less noise effect and could execute active line measurement. It is possible to analyze main discharge phenomena and obtain access to aging progress occurred in insulation materials through accumulation of HFPD signals during determined interval and expression of fractal dimension using statistical process of accumulated signals. In this study, the statistical parameters (skewness & kurtosis) and fractal dimensions are changed by discharge patterns that is shown up different characteristics with applied voltages and times.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2003년도 추계학술발표논문집 (상)
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• pp.571-574
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• 2003

본 논문에서는 다중해상도에서 기존의 그레이 블록 거리(grey biock distance; GBD, 이하 GBD)알고리즘과 비교하여 이차원 영상간의 상대적 식별을 더 용이하게 하기 위한 새로운 GBD 알고리즘 방법을 제안한다. 이 제시된 방법은 다중해상도에서 기존의 GBD 알고리즘과 비교해서 영상이 급격히 변화하는 부분의 정보를 잃지 않게 개선할 수 있었다. 모의 실험 예로서 주성분분석(principal component analysis; 이하 PCA) 기법을 적용하여 유용성과 제안된 방법이 이전의 연구보다 k가 감소할 때 편차는 줄어들어 좋은 영상 분류 특징을 보였으며, 첨도(Kurtosis)에서의 영상간의 거리 측정 결과 첨도가 가지고 있는 특성에 의해 영상 분류 시 매우 민감한 반응을 나타내어 k가 4까지만 블록을 분할 할 수 있음을 모의 실험을 통하여 확인할 수 있었다.

• Communications for Statistical Applications and Methods
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• 제5권3호
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• pp.887-894
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• 1998

Let T=( $T_1$,…, $T_{k}$;k$\geq$2) be a minimal sufficient and complete statistic for a k-parameter exponential model. Consider a partition of T into ( $T_1$, $T_2$), where $T_1$=( $T_1$,…, $T_{r}$ and $T_2$=( $T_{r+1}$,…, $T_{k}$1$\leq$r$\leq$k-1/). This article represents a way to obtain higher moments such as skewness and kurtosis for the distribution T and the conditional distribution of $T_1$, given $T_2$= $t_2$. These results are illustrated by some examples.s.les.s.

• Communications for Statistical Applications and Methods
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• 제23권4호
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• pp.321-334
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• 2016

In this paper, we propose power t distribution based on t distribution. We also study the properties of and inferences for power t model in order to solve the problem of real data showing both skewness and heavy tails. The comparison of skew t and power t distributions is based on density plots, skewness and kurtosis. Note that, at the given degree of freedom, the kurtosis's range of the power t model surpasses that of the skew t model at all times. We draw inferences for two parameters of the power t distribution and four parameters of the location-scale extension of power t distribution via maximum likelihood. The Fisher information matrix derived is nonsingular on the whole parametric space; in addition we obtain the profile log-likelihood functions on two parameters. The response plots for different sample sizes provide strong evidence for the estimators' existence and unicity. An application of the power t distribution suggests that the model can be very useful for real data.

• 한국컴퓨터정보학회:학술대회논문집
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• 한국컴퓨터정보학회 2013년도 제48차 하계학술발표논문집 21권2호
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• pp.355-356
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• 2013

심장의 활동을 전기적 변위로 표현되는 심전도 신호는 심장병 진단에 중요한 임상적 파라미터들을 제공한다. 특히 심전도 신호에서 P, QRS Complex,, T 특징점들로 대표되는 파형 변곡점들의 시간상 위치와 크기 및 형태학적 모양은 심장의 이상 리듬을 나타내는 부정맥여부를 검출하는데 핵심적인 역할을 한다. 본 연구에서는 특히 QRS complex 구간에 대한 첨도치의 연산 해석을 통하여 정상적인 심전도 리듬과 심실조기수축 부정맥 리듬을 구분하는 방법을 제시하고 또한 스마트폰을 기반으로 하는 심전도 모니터링 시스템에 적용하고자 하였다.

• E2M - 전기 전자와 첨단 소재
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• 제10권3호
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• pp.247-254
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• 1997

Internal voids in insulators give rise to partial discharge, which causes a local breakdown and even entire insulation breakdown. Recently, the necessity of establishing the way to diagnose the aging of insulation materials and to predict of insulation breakdown become important. The purpose of our work are to investigate the treeing phenomena with an artificial needle shaped void by the charge of discharge and acoustic emission pulse in each phase angle area at the same time. We analyzed the .PHI.-QA-t pattern and .PHI.-AEA-t pattern using statistic operators such as pulse magnitude, pulse number, skewness, kurtosis. Therefore, the relation between the charge of discharge and acoustic emission pulse will be helpful to predict the breakdown just before the breakdown occur.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1998년도 하계학술대회 논문집 D
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• pp.1478-1480
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• 1998

Inception and propagation of electrical tree and properties of partial discharge(PD) pulses accompanying with tree in low density polyethylene were discussed. We observed the characteristics of process of electrical tree by using optical microscope and investigated the statistical characteristics of the PD pulses by analyzing PD quantities and distribution patterns. The PD pulses were analyzed by q-n, $\phi$-n and $\phi$-q distribution. The statistical operators used were skewness(s), kurtosis(k) and average phase angle. The skewness and average discharge phase angle of PD pulses increased as the Propagation of tree. The kurtosis was about 1.8 at the Inception of tree, but It increased as the propagation of tree.

• International Journal of Fluid Machinery and Systems
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• 제1권1호
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• pp.109-120
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• 2008

An innovative method of changing a centrifugal low specific speed pump performance and pressure fluctuation by applying outlet flaps to impeller exit has been investigated. The outlet blade edge section corresponds to the trailing edge of wing on the circular-cascade, which dominates the pump performance and pressure fluctuation. Computational fluid dynamics (CFD) analysis of the entire impeller and volute casing and an experimental investigation are conducted. The pressure fluctuation and the vibration of the shaft are measured simultaneously. Kurtosis is applied as a dimensionless parameter with which the unevenness of velocity distribution at impeller outlet is indicated. The influence of the flaps on the pressure fluctuation is explained by the kurtosis. This paper presents a theoretical method of predicting the pump performance related to the attachment of a flap at impeller outlet.