• 한국노년학
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• v.28 no.4
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• pp.1023-1039
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• 2008

The purpose of this study was to develop a group validation therapy(V/T) which could be implemented for the elderly with dementia in nursing home, and to evaluate the effectiveness of the program on cognition, ADL(Activity of Daily Living), depression, problematic behavior and QOL(Quality of Life). Subjects were recruited from 4 nursing homes in D city. The sample comprised forty elderly with dementia, capable of verbal communication. Each twenty were in an experimental and control groups. However, four elders with dementia dropped out in experimental and control groups due to personal affairs. Experimental group completed twelve consecutive group validation therapy sessions that combined centering, asking factual questions, rephrasing, identifying and using the preferred sense, asking the extreme, imagining the opposite, reminiscing, touching, maintaining eye contact and a caring tone of voice, observing, matching and expressing the emotion with emotion, using ambiguity, linking behavior with a basic human need, using music and mirroring techniques. Following the intervention, experimental group experienced a significant improvement in cognition, ADL, depression, and QOL. But it is a nonsignificant in problematic behavior on statistically. As a result, a group validation therapy should be applied as an effective and practical psychosocial intervention for the elderly with dementia.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.675-677
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• 2005

This study proposes a fuzzy classification using EM algorithm. For cluster validation, this approach iteratively estimates the class-parameters in the fuzzy training for the sample classes and continuously computes the log-likelihood ratio of two consecutive class-numbers. The maximum ratio rule is applied to determine the optimal number of classes.

• ALGAE
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• v.22 no.2
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• pp.53-55
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• 2007

The name Palisada, which recently was proposed but not validly published for a new genus in the Laurencia complex,is validated by the provision of a Latin diagnosis. Relevant omenclatural changes for several species of Chondrophycus are included.

• Microbiology and Biotechnology Letters
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• v.36 no.1
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• pp.12-20
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• 2008

Validation of viral safety is essential in ensuring the safety of mammalian cell culture-derived biopharmaceuticals, because numerous adventitious viruses have been contaminated during the manufacture of the products. Mammalian cells are highly susceptible to minute virus of mice(MVM), and there are several reports of MVM contamination during the manufacture of biopharmaceuticals. In order to establish the validation system for the MVM safety, a real-time PCR method was developed for quantitative detection of MVM in cell lines, raw materials, manufacturing processes, and final products as well as MVM clearance validation. Specific primers for amplification of MVM DNA was selected, and MVM DNA was quantified by use of SYBR Green I. The sensitivity of the assay was calculated to be $6{\times}10^{-2}TCID_{50}/mL$. The real-time PCR method was proven to be reproducible and very specific to MVM. The established real-time PCR assay was successfully applied to the validation of Chinese hamster ovary (CHO) cell artificially infected with MVM. MVM DNA could be Quantified in CHO cell as well as culture supernatant. When the real-time PCR assay was applied to the validation of virus removal during a virus filtration process, the result was similar to that of virus infectivity assay. Therefore, it was concluded that this rapid, specific, sensitive, and robust assay could replace infectivity assay for detection and clearance validation of MVM.

• Journal of Navigation and Port Research
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• v.39 no.1
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• pp.15-21
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• 2015

In high precision positioning systems based on GNSS, ambiguity resolution is an important procedure. Correct ambiguity leads to positioning results which have high precision between millimeters and centimeters. However, when the ambiguity is determined incorrectly, ensuring accuracy and precision of the positioning result is impossible. An ambiguity validation test is required to obtain correct ambiguity when ambiguity resolution is performed based on the ILS (Integer Least Squares), which shows the best performance in point of theory and experiment when compared with other methods such as IR (Integer Rounding) and IB (Integer Bootstrapping). Comparison between the candidates of the validation test is needed to judge ambiguity correctly, because ILS searches for candidates of integer ambiguity, unlike other methods which calculate only one integer ambiguity. We analyzed the experimental performance of ambiguity validation tests. R-ratio, F-ratio and W-ratio were adopted for analysis. The performance of validation tests was evaluated by classifying normal operation, detection, missed detection and false alarm. As a result, strengths and weaknesses of validation tests was showed to experimental. we concluded that validation tests must be selected according to environment.

• Journal of Food Hygiene and Safety
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• v.34 no.4
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• pp.374-379
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• 2019

This study developed predictive growth models of Salmonella enterica Serovar Typhimurium on lettuce washed with chlorine (100~300 ppm) and ultrasound (US, 37 kHz, 380 W) treatment and stored at different temperatures ($10{\sim}25^{\circ}C$) using a polynomial equation. The primary model of specific growth rate (SGR) and lag time (LT) showed a good fit ($R^2{\geq}0.92$) with a Gompertz equation. A secondary model was obtained using a quadratic polynomial equation. The appropriateness of the secondary SGR and LT model was verified by coefficient of determination ($R^2=0.98{\sim}0.99$ for internal validation, 0.97~0.98 for external validation), mean square error (MSE=-0.0071~0.0057 for internal validation, -0.0118~0.0176 for external validation), bias factor ($B_f=0.9918{\sim}1.0066$ for internal validation, 0.9865~1.0205 for external validation), and accuracy factor ($A_f=0.9935{\sim}1.0082$ for internal validation, 0.9799~1.0137 for external validation). The newly developed models for S. Typhimurium could be incorporated into a tertiary modeling program to predict the growth of S. Typhimurium as a function of combined chlorine and US during the storage. These new models may also be useful to predict potential S. Typhimurium growth on lettuce, which is important for food safety purposes during the overall supply chain of lettuce from farm to table. Finally, the models may offer reliable and useful information of growth kinetics for the quantification microbial risk assessment of S. Typhimurium on washed lettuce.

• Journal of Korean Academy of Nursing
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• v.28 no.3
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• pp.563-572
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• 1998

The purpose of study was to develop and validate Korean Sleep Scale A which can be easily administrated by nurses for a wide range of adult subjects. Dimensions of sleep concept were derived by literature review. Previously developed sleep sclaes were also analyzed in order to develop scale items. The Korean sleep scale A was structured as a 15 item, 4 point likert type scale. The Scale was tested an 298 female and male adult subjects after pilottest and content validation. The results showed reliability by internal consistency of Cronbach's α=.75 Construct validity was tested by factor analysis and known group technique. Factor analysis showed 4 factors-sleep pattern, sleep evaluation, sleep result, and cause of sleep disturbance. These four factors explained 55.9% of total variance. Correlations between factors ranged from .15-.32. There was correlation among Korean Sleep ScaleA score, Verran and Snyder-Halpern(VSH) Sleep Scale score, and sleep satisfaction scale score, r=.71(p=.00), r=.51(p=.03), respectively, These study results partially support reliability, construct validity, and criterion related validity of Korean Sleep Scale A. Further validation study is required with other subjects and other settings.

• Journal of Korean Academy of Nursing
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• v.41 no.3
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• pp.374-381
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• 2011

Purpose: The purpose of this study was to develop and validate a hospice palliative care performance measure which would cover more than just physical symptoms or quality of life. Methods: Through an intensive literature review, the author chose questions that measured aspects of physical, emotional, spiritual, social, or practical domains pertinent to hospice palliative care for inclusion in the scale. Content validation of the questions was established by 15 hospice palliative care professionals. A preliminary Hospice Palliative Care Performance Scale (HPCPS) of 20 questions was administered to 134 pairs of terminal cancer patients from 5 hospice palliative care units and their main family caregiver. A validation study was conducted to evaluate construct validity and internal consistency. Results: Factor analysis showed 14 significant questions in five subscales; Physical, Emotional, Spiritual, Social, and Patient' rights. There were no significant differences between the ratings by patients and family members except for three out of the 14 questions. The measure demonstrated construct validity, and Cronbach's ${\alpha}$ of the subscales ranged from .73 to .79. Conclusion: The HPCOS demonstrated acceptable validity and reliability. It can be used to assess effectiveness of hospice palliative care for terminal cancer patients in practice and research.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.19 no.3
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• pp.288-296
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• 2009

We conducted validation for asbestos quality control (QC) samples made by the developed method which was presented in our published paper. The main results of the validation study are as follows. The pooled coefficient variations of analytical results in three different concentrations (low, medium, and high concentration) for amosite and chrysotile were less than 20 %, which met the sample homogenicity criteria of NIOSH. Also we confirmed the homogenicity of asbestos samples by using the relocatable field slide. To evaluate the field applicability of the developed asbestos QC samples, the field validation was performed with four proficient asbestos analysts by using the statistical methods of AIHA asbestos PAT program. All analytical results from four asbestos analysts were located in the acceptable range.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.40 no.6
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• pp.548-554
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• 2012

Verification and validation of operational software of the flight control computer, which is flight safety critical, is very important to prove correctness and faultness of the software. To verify the real-time softare requirement on operational software of flight control computer, real-time software internal parameter and variable monitoring technics on hardware-in-the-loop environment, similar to on-flight environment, is required. This paper describes flight safety critical software validation and verificiation environment using standard debugging interface, NEXUS 5001.