• Journal of Ginseng Research
• /
• v.46 no.6
• /
• pp.759-770
• /
• 2022

Background: Aerobic cellular respiration provides chemical energy, adenosine triphosphate (ATP), to maintain multiple cellular functions. Sirtuin 1 (SIRT1) can deacetylate peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) to promote mitochondrial biosynthesis. Targeting energy metabolism is a potential strategy for the prevention and treatment of various diseases, such as cardiac and neurological disorders. Ginsenosides, one of the major bioactive constituents of Panax ginseng, have been extensively used due to their diverse beneficial effects on healthy subjects and patients with different diseases. However, the underlying molecular mechanisms of total ginsenosides (GS) on energy metabolism remain unclear. Methods: In this study, oxygen consumption rate, ATP production, mitochondrial biosynthesis, glucose metabolism, and SIRT1-PGC-1α pathways in untreated and GS-treated different cells, fly, and mouse models were investigated. Results: GS pretreatment enhanced mitochondrial respiration capacity and ATP production in aerobic respiration-dominated cardiomyocytes and neurons, and promoted tricarboxylic acid metabolism in cardiomyocytes. Moreover, GS clearly enhanced NAD⁺-dependent SIRT1 activation to increase mitochondrial biosynthesis in cardiomyocytes and neurons, which was completely abrogated by nicotinamide. Importantly, ginsenoside monomers, such as Rg1, Re, Rf, Rb1, Rc, Rh1, Rb2, and Rb3, were found to activate SIRT1 and promote energy metabolism. Conclusion: This study may provide new insights into the extensive application of ginseng for cardiac and neurological protection in healthy subjects and patients.

• Korean Journal of Acupuncture
• /
• v.34 no.3
• /
• pp.172-178
• /
• 2017

Objectives : The purpose of this study is to report a case of traditional Korean Medicine effect on a patient with rhabdomyolysis who appealed leg pain, numbness and weakness. Methods : A patient received traditional Korean Medicine including acupuncture, herbal medicine, moxibustion, and cupping therapy daily. We evaluated the clinical results by observing the patient's symptoms, NRS(Numerical Rating Scale), MMT(Manual Muscle Test) grade and DITI(Digital Infrared Thermal Imaging). Results : After traditional Korean Medicine, the patient's pain and numbness decreased from NRS 10 to 1~2 and weakness improved from Gr3- to Gr4. And CPK(creatine phosphokinase) numerical value decreased from 330(IU/L) to 164 and body heat status improved. Conclusions : Traditional Korean Medicine can be effective in reducing rhabdomyolysis patients' symptoms and changing examination numerical value. And further studies on traditional Korean Medicine of rhabdomyolysis should be carried out.

• The Journal of Internal Korean Medicine
• /
• v.43 no.5
• /
• pp.795-808
• /
• 2022

Objectives: The purpose of this study is to report two cases of prostate cancer patients whose side effects after surgery were treated with traditional Korean medicine. Methods: Two prostate cancer patients underwent robot-assisted laparoscopic prostatectomy, and both patients were treated with traditional Korean medicine. Subjective discomfort symptoms were evaluated using the Numerical Rating Scale. Adverse events were evaluated using the National Cancer Institute Common Terminology Criteria for Adverse Events, version 5.0. Daily life vitality was evaluated by the Eastern Cooperative Oncology Group. Results: After treatment with traditional Korean medicine, discomfort symptoms that occurred after surgery, such as frequent urination, nocturia, insomnia, and depression, all gradually improved, and Eastern Cooperative Oncology Group scores also improved from two points to one point. Additionally, there were no hematologic side effects from the traditional Korean medicine treatment. Conclusions: This case study suggests that traditional Korean medicine may contribute to the improvement of side effects caused by robot-assisted laparoscopic prostatectomy, quality of life, and immunity.

• The Journal of Internal Korean Medicine
• /
• v.33 no.2
• /
• pp.111-125
• /
• 2012

Objectives : One of the fundamental premises of medical anthropology is the interconnectedness of medicine and society. Recent ethnographies of medicine demonstrate that the interconnectedness of the social and the medical not just evokes relatedness of the two parties, but also emphasizes the agency of the constituents, mutually shaping and being shaped. Against this backdrop, this study attempts to anthropologically investigate Korean medicine in South Korea and traditional Chinese medicine (TCM) in China. Methods : The findings are based on anthropological studies of East Asian medicine employing long-term fieldwork about Korean Medicine and Traditional Chinese Medicine. Results : TCM is characterized by standardization, hospitalization, and scientization, by which simplification, collectivization, and biomedicalization prevail in contemporary traditional medicine in China. In contrast, Korean medicine is characterized by diversity, care delivery by individual private clinics, and a considerable distance from biomedicine. To understand the divergence of the two East Asian medicines, one should consider the social contexts intervening into the medical contents, such as the role of the state and dominant discourses in given historical periods. Conclusions : Korean medicine in South Korea and TCM in China demonstrate well the hybridity of the social and the medical, suggesting that, for more comprehensive understanding of the medical, the social should be paid attention to.

• Korean Journal of Oriental Medicine
• /
• v.16 no.1
• /
• pp.85-92
• /
• 2010

Objective : This article reviewed China's intent and aim of the failed attempt to register Traditional Chinese Medicine(TCM) as UNESCO's Intangible Cultural Heritage, its process and implication as a policy of 21st Traditional Chinese Medicine(TCM) promotion on the landscape of North East Asian medical geopolitcs. Methods : This article utilized mainly the discourse analysis of vernacular Chinese journals and newspaper reports. Conclusions : It is needed to design effective strategies for securing Traditional Korean Medicine(TKM)'s identity and authenticity to cope with so-called 'Chinese Medicine Domination Project'.

• The Journal of Korean Medicine
• /
• v.20 no.3 s.39
• /
• pp.9-17
• /
• 1999

Objectives: Recently a renovation of the medical-welfare system to reflect the changes of disease spectrum with the demographic changes of society, the increase in income level, and marked concerns for health promotion has been demanded. In accordance with this, attempts have been made to actively integrate traditional medicine based on symptom-differentiated treatment and Western medicine based on disease treatment so that they can complement each other. China has already tried a complementary medical treatment system integrating traditional Chinese and Western medicine. So, this article reviewed major advances in research on integrated traditional Chinese medicine and Western medicine in China. Methods: The authors analyzed data from clinical articles and experimental works in the ' Chinese Journal of Integrated Traditional and Western Medicine' Results and conclusions: Each department attempted to integrate Traditional Chinese Medicine(TCM) and Western Medicine in treatment of various diseases such as malaria, AIDS, and intoxication (rarely found in Korea clinically). Especially in the departments of surgery, dentistry, radiology, and anesthesiology we could see the frequent use of combined treatment. TCM and Western medicine complemented each other very successfully, and the effect of the combined therapy was superior to that of traditional therapy alone. There were diverse methods for therapy in integrated TCM and Western medicine; bath-Tx, physical-Tx, manipulative-Tx, drug -acupuncture, Tibetan medicine, etc. were available in therapy as well as traditional methods such as acupuncture, moxibustion, and negative- Tx. The way of producing Chinese medications were diversified and formulated; making new prescriptions, compounding various kinds of new medicine called' Zhong Cheng Yao' (中成藥) which were easily made, stored, and taken. 'Diagnosis Criteria', 'The effect of TCM Treatment Criteria' were made by committee and broadly used for objectifying diagnosis, discriminating effects of treatments and treatment development, and developing new medical products.

• 한국약용작물학회:학술대회논문집
• /
• 2012.05a
• /
• pp.125-126
• /
• 2012

• Korean Journal of Oriental Medicine
• /
• v.13 no.3
• /
• pp.143-149
• /
• 2007

Objectives : This study aimed to evaluate present status and future of traditional medical service market, focusing on the Korean medical center. Methods: We chose the subject with simple random sampling and investigated through interview and internet with questionnaire. Total 319 people helped us. Results: 1. It was investigated that, the number of the Korean medical centers which was operating traditional medical service was 9,910. And the number of people in the business of traditional medical service was estimated by total 46,577 in 2005. 2. Average sales of Korean medical center in 2003 was 24.8 million won. increased by 25.6million won in 2004, 28.3million won in 2005. 3. At the end of 2005, the scale of traditional medical service market was estimated by 2 trillion 7,676 hundred million won. Conclusions : Korean traditional medical service industry has been developed and will be developing by 2.8 times in 2015.

• Journal of Society of Preventive Korean Medicine
• /
• v.9 no.1
• /
• pp.77-89
• /
• 2005

Since 1990's, the Korean society, experiencing the low fertility and aging society, has been confronting with the threats in health care sector. The threats are the increases in the demand for health care, health care financial burden, and so on. In particular, the change of disease pattern and aging population result in the increases patients' demand for not only western medical services but also oriental medical services and complimentary medicine. Recently, the increases in availability of oriental medical services and the health care resources related to oriental medicine are raising some issues and conflicts in the Korean health sector. Theses circumstance required policy makers, central and local government, and public health sector to develop health policies related to oriental medicine and interface or integrate of traditional Korean medicine and Western medicine. For the near future, these issues will probably remain the focus of integration of traditional Korean medicine and Western medicine in public health sector. To cope with the threats in health care sector, one of the opportunities is to scale-up e public role of traditional Korean medical services. The main purpose of this study was to develop strategies to scale-up the Public role of traditional Korean medical services for the future society. The research questions are: what are the trends and problems in traditional Koran medical sector; what are the causes of or associated factors to the problems; how to cope with the problems and how to resolve the cause?; what are the health policy directions and its strategies that the government should take to cope with the future demand and the burden on health care sector? The results of this study are as follows. In order ta scale-up the public role of traditional medicine, this research offered health policy directions for traditional Korean medicine in response to a change environment of health care sector. There are four directions to be addressed: 1) the development of and investment in public oriental medicine infra-structure; 2) the development of public policy on oriental medicine; 3) modernization and globalisation of traditional Korean medicine; 4) the expansion of academic exchange between Western medicine and traditional Korean medicine. Finally, we discussed stakenholders' on traditional Korean medicine in the health care market. Then, public policy options for future society was suggested.

• The Journal of Churna Manual Medicine for Spine and Nerves
• /
• v.17 no.1
• /
• pp.35-46
• /
• 2022

Objectives This study aimed to review clinical studies on traditional Korean medicine treatment for medial collateral ligament injury of the knee. Methods Clinical studies on Korean traditional medicine treatment of medial collateral ligament injury were conducted. We used five Korean online databases (OASIS, KISS, RISS, DBPia, and ScienceOn) and three foreign databases (PubMed, Cochrane Library, and CNKI). Out of 99 studies that were found, we excluded repeated articles, studies that were not related to Korean medicine, and those not relevant to the topic of the study. Results Ten randomized controlled trials and 20 case studies were selected. Eight traditional Korean medicine treatments, including acupuncture, herbal medicine, chuna, and herbal ointment, were used in these studies. The most commonly used treatment was found to be acupuncture. Conclusions Our study showed that traditional Korean medicine for medial collateral ligament injuries was effective. However, there were some limitations. Further clinical studies and randomized controlled clinical trials are needed for more evidence on Korean traditional medicine.