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The Evaluation of Clinical Usefulness on Application of Myocardial Extract in Quantitative Perfusion SPECT (QPS 프로그램에서 Myocardial extract 적용에 따른 임상적 유용성 평가)

  • Yun, Jong-Jun;Lim, Yeong-Hyeon;Lee, Mu-Seok;Song, Hyeon-Seok;Jeong, Ji-Uk;Park, Se-Yun;Kim, Jae-Hwan;Kim, Jeong-Uk
    • The Korean Journal of Nuclear Medicine Technology
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    • v.15 no.2
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    • pp.88-93
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    • 2011
  • Purpose: As to analytical method of data, the AutoQUANT software in which it is used quantitative rating of the myocardial perfusion SPECT are reported that there is a difference. Therefore the measured value error of the mutual program is expected to be generated even if the quantitative analysis is made data of the same patient. The purpose of this study is to offer the comparative analysis of myocardial extract method in Quantitative Perfusion SPECT. Materials and methods: We analyzed the 51 patients who were examined by Tc-99m MIBI gated myocardial SPECT in nuclear medicine department of Pusan National University Hospital from June to December 2010(34 men, 17 women, mean age $66.5{\pm}9.9$). We acquired the extracted image in myocardial extract protocol. QPS program that uses the AutoQUANT software measured TID(Transient Ischemic Dilation), ESD(Extent of Stress Defect), SSS(Summed Stress Score). Then analyzed the results. Results: The correlation of appyling myocardial extract is TID(r=0.98), ESD(r=0.99), SSS(r=0.99). In the 95% confidence limit, there was no satistically significant difference(TID p=0.78, ESD p=0.31, SSS p=0.19). After blinding test with a physician for making a qualitative analysis, there was no difference. Conclusion: Quantitative indices in QPS program showed good correlation and the results showed no statistically signigicant difference. The variance between method was small. therefore, the functional parameters by each method can be used interchangeably. Also, we expect patient's satisfaction.

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The Reduction ways of Medicine Material Costs of Nuclear Medicine In Vitro (핵의학 체외검사의 진료재료비용 절감 방안)

  • Song, Hun-Kang;Seo, Jung-Mi;Yang, Joon-Ho;Kim, Eun-Jung;Kim, Chang-Ho
    • The Korean Journal of Nuclear Medicine Technology
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    • v.15 no.2
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    • pp.111-115
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    • 2011
  • Purpose: In vitro uses dose response curve with 6 to 7 standard concentrations in every examination to analyze examination results and this use of dose response curve comprises a large portion of the consumption of medicine material. At this present, some ones of in-hospital examination items have shown mostly low result of distribution in the analyzed features and these examinations have been judged that it would be unnecessary to use the last standard concentration. Hence, this study selects those examination items showing low result of distribution and reviews the cases contributed to less consumption of medicine material and revenue growth of hospital by reduction of medicine material used in the place of the last standard concentration. Materials and Methods: The study was made targeting 11 examination items out of total 43 items of the in-hospital examination and since these examination items were mostly low in the features as the examination results of patients or the examination results were distributed to show lower concentration than the previous last standard concentration, it carried out the examination without using the last standard concentration, which could generate the effect to reduce medicine material (examination tube) used in the last standard concentration as many as the number of examination carried out. For this, it examined the number of medicine material reduction by month during the period from July, 2009 to February, 2011 and estimated the reduction amount of medicine material calculated the number of reduction by the unit cost of medicine material as well as the profit generated by the reduced medicine material to use for the medicine material of patient examination. Results: The total number of medicine material reduced during the period from July, 2009 to February, 2011 was 3,131 pieces, which had the effect to reduce the medicine material equivalent to about 31 kits of reagent. To calculate this by the unit cost of the medicine material, it analyzed to reduce about 6.4 million won of medicine material cost. Also the reduced medicine materials were used for medicine materials of patient examination and this was analyzed to generate about 13.75 million won of profit based on the ABC cost accounting. Conclusion: It showed no problem in the analysis of examination result even without using the last standard concentration regarding those examination items with low distribution of the patient examination result. For these examination items, it was able to reduce medicine material used for the last standard as many as the number of examination carried out. Also, the adjustment of concentration range was found to have no problem in the reliability of examination result. Therefore, this case will be applicable in those occasions of when the analysis of patient examination result is mostly distributed at the lower level or when an examination with the distribution of patient results in the range of lower concentration than the previous last standard concentration is carried out and this is considered to increase the efficiency in the use of medicine material in vitro as well as contribute to the profit of hospitals.

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Prevalence of Salmonella Species Isolated from Old Hen Delivery Trucks in Korea and Application of Disinfectant for the Reduction of Salmonella Contamination (국내 노계 운반 전용 차량에서의 살모넬라 오염율 및 차량소독에 따른 오염도 감소 효과)

  • Na, Deok-Hwan;Hong, Young-Ho;Yoon, Mi-Young;Park, Eun-Jin;Lim, Tae-Hyun;Jang, Jun-Hyuk;Kim, Byoung-Youn;Lee, Dong-Hun;Song, Chang-Seon
    • Korean Journal of Poultry Science
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    • v.40 no.1
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    • pp.11-16
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    • 2013
  • Salmonella is closely related with human health of modern society which has concern increased in livestock goods consumption as well as give economic damage throughout the chicken industry such as farm, hatchery, slaughter house and processing plant. From 2007 to 2011, this study investigated Salmonella prevalence from 200 old hen delivery trucks which deliver old egg-laying hens and broiler breeders in Korea. The prevalence of Salmonella species was 38.0% in old hen delivery truck. Serogroup C1 was the most frequently detected serogroup of Salmonella, followed by the serogroups D1, C2 and B. A total of 25 serotypes were identified and Salmonella infantis was the most frequently isolated serotype. In addition, we applied disinfectant to old hen delivery truck for the reduction of Salmonella contamination. The disinfectant consists of formaldehyde, glutaladehyde and quaternary ammonium compound was applied to the trucks. Salmonella isolation rate was significantly decreased after disinfection from 38.0% to 7.5%. Disinfectant could not effectively reduce Salmonella contamination at a dilution of 1:200 which is recommended by manufacturer, but Salmonella isolation rate was significantly decreased at a dilution of 1:50. Since old hen delivery truck could be a potential vector to carry Salmonella into farms and abattoirs, chicken delivery truck should be disinfected thoroughly and sufficiently to control contamination of farms and abattoirs.

The effect of surface treatment conditioning on shear bond strength between zirconia and dental resin cements (지르코니아 세라믹의 표면처리에 따른 치과용 접착제의 전단결합강도)

  • Kim, Ji-Hye;Seo, Jae-Min;Ahn, Seung-Geun;Park, Ju-Mi;Song, Kwang-Yeob
    • The Journal of Korean Academy of Prosthodontics
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    • v.51 no.2
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    • pp.73-81
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    • 2013
  • Purpose: The purpose of this study was to evaluate the effect of surface treatment on the shear bond strength of zirconia ceramic to 3 resin cements. Materials and methods: A total of 143 disk-shaped Zirconia blocks (HASS Co., Gangneung, Korea) were randomly divided into three treatment groups: (1) only 50 ${\mu}m$ $Al_2O_3$ sandblasting, (2) 50 ${\mu}m$ $Al_2O_3$ sandblast and zircona liner, (3) 50 ${\mu}m$ $Al_2O_3$ sandblasting and Rocatec (3M ESPE, Seefeld, Germany). Bistite II (Tokuyama Dental Co., Japan), Panavia F (Kuraray Medical, Japan), and Superbond C&B (Sun Medical, Japan) were used to cement onto the zirconia. After 24h of storage in distilled water, shear bond strength was evaluated. High value group was re-tested after thermocycling at 5,000 cycles(5-$55^{\circ}C$). Shear bond strength data were analyzed with one-way ANOVA, two-way ANOVA test and Post Hoc Test (${\alpha}$=.05). Shear bond strength data before and after thermocycling were analyzed with Independent sample T test (${\alpha}$=.05). Results: Super-bond C&B treated with Rocatec showed the most high shear bond strength. Super-bond C&B groups resulted in significantly higher than other cement groups (P<.05). Rocatec groups resulted in significantly higher than other surface treatment groups (P<.05). Shear bond strength has increased in Panavia F treated with Zirconia liner (P<.05). After thermocycling, shear bond strength was increased in Super-bond C&B treated with Rocatec but decreased in other groups (P<.05). Conclusion: Super-bond C&B cement resulted the highest shear bond strength and Rocatec system enhanced the shear bond strength. After thermocycling, shear bond strength has decreased in most resin cements except Super-bond C&B treated with Rocatec.

Andic Properties of Major soils in Cheju Island 1. Characterization of Volcanic Ash Soils by Selective Dissolution Analysis (제주도(濟州島) 대표토양(代表土壤)의 Andic 특성(特性)에 관(關)한 연구(硏究) 1. 선택적(選擇的) 추출방법(抽出方法)에 의(依)한 화산회토(火山灰土)의 특성(特性) 구명(究明))

  • Song, Kwan-Cheol;Yoo, Sun-Ho
    • Korean Journal of Soil Science and Fertilizer
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    • v.24 no.2
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    • pp.86-94
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    • 1991
  • Volcanic ash soils were classified as Andepts, a suborder of the Inceptisols in Soil Taxonomy. Increased knowledge on the volcanic ash soils necessitated and facilitated considerable improvement in this system. As a result, the new Order of Andisols was incorporated in the 1990 edition of the Keys to Soil Taxonomy. The central concept of an Andisol is that of a soil developing in volcanic ejecta, and/or in volcaniclastic materials, whose colloidal fractions are dominated by short-range-order minerals or Al-humus complexes. Andic propertis of volcanic ash soil in Cheju Island were investigated. For this study, soils of toposequence distributed along the southern slope of Mt. Halla, and the major soil groups such as dark brown soils, very dark brown soils, black soils, and brown forest soils were collected and analyzed for Al, Fe and Si extracted with solutions of pyrophosphate, dithionite-citrate. and oxalate respectively. Weolpyeong and Yongheung soils developed on the lower elevations contain only small amounts of allophane and Al-and Fe-humus complexes. For other soils, allophane content decrease with elevation and increaes with soil depth,whereas Al-humus complexes increase with elevation and decrease with soil depth. Substantial amount of allophane and ferrihydrite are found in all horizons of Ora and Ara soils developed on 150-300m elevations and of Noro and Jeogag soils developed on cinder cones. In the A horizons of Pyeongdae, Tosan and Heugag soils developed on the higher elevations, Al-humus complexes are dominant form of Al reflecting low pH and high organic matter content. However, lower horizons are dominated by allophane.

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Effect of Ethephon and Diquat Dibromide Treatment for Triticale Seed Production on Paddy Field (트리티케일 종자 안정 생산을 위한 생장억제제 및 건조제 처리 효과)

  • Cho, Sang-Kyun;Park, Hyeong-Ho;Oh, Young-Jin;Cho, Kwang-Min;Jang, Yun-Woo;Song, Tae-Hwa;Park, Tae-Il;Kang, Hyun-Jung;Roh, Jae-Hwan;Park, Kwang-Geun
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.59 no.1
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    • pp.59-65
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    • 2014
  • As for Ethephon treatment, the heading stage is 2 days later at the concentration of 250 ppm and 500 ppm for the booting stage that when there is no treatment, 4 days later at the concentration of 1000 or more ppm but no difference for the blossoming and ripening stage. The culm length get shorter as the concentration of Ethephon is higher and the rate of culm length damaged is 37% for 1500 ppm of booting stage, which is the most effective processing, and the inferior culm length damage rate is bigger than the superior culm length damage rate. There is no difference between the number of glumous flower, culm and litter weight and the non-processing and as for the thousand grain weight, it is slightly bigger than when there is not any processing. The rate of germination is indifferent, the number of seeds get numerous regardless of the concentration of treatment and the number augments by 5% maximum for the booting stage. The number of days it takes from treatment of desiccant to the moisture content for harvesting time is respectively 15 days for seeds of 30 day-treatment, 10 days for seeds of 35 days-treatment and 5 days for seeds of 40 to 45 day-treatment. As for the harvest time after treatment of desiccant, the treatment at $30^{th}$ days and $35^{th}$ after the earing is 8 days earlier than the culture by conventional methods, 8 days earlier for the treatment at $40^{th}$ day. When the desiccant treatment is implemented, the thousand grain weight is heavier as the number of days of treatment gets later. The rate of germination gets higher as the number of days of treatment after earing gets later but there is no statistically significant difference 35 days after the earing. Yields are 37% compared to the culture by conventional methods for the treatment of 30 days after the earing, 70% compared to the culture by conventional methods for the treatment of 35 days after the earing, and 92% compared to the culture by conventional methods for the treatment of 40 days after the earing. The treatment before the physiological maturity impacts greatly upon the quality of seeds.

Study on the DBH Analysis and Forest Succession of Pinus densiflora and Quercus mongolica Forests (소나무림(林)과 신갈나무림(林)의 흉고직경급(胸高直徑級) 분석(分析)과 천이(遷移)에 관(關)한 연구(硏究))

  • Song, Ho Kyung;Jang, Kyu Kwan
    • Journal of Korean Society of Forest Science
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    • v.86 no.2
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    • pp.223-232
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    • 1997
  • One hundred Sixty two quadrats were sampled from natural forests, in Kangwon-do and Kyungsangbuk-do. On the basis of Mueller-Dombois & Ellenberg method, field survey, which accounts for the characters of the species structure of Pinus densiflora community and Quercus mongolica community, was carried out between 1991 and 1994. To analyze the data, CCA ordination and D.B.H, analysis were used. 1. DBH analysis showed that Pinus densiflora community is likely replacing Quercus mongolica or Quercus variabilis community. DBH analysis also showed that Quercus mongolica - Lindera obtusiloba community balances among the Quercus mongolica, Fraxinus rhynchophylla, and Tilia amurensid in the canopy, and that Quercus mongolica-Abies nephrolepis community, mixed forest balances among the Quercus mongolica, Pinus koraiensis, and Abies nephrolepis in the canopy. In general, Quercus mongolica seems to remain as a dominant species. 2. A certain correlation seems to exist between nutrients types and Pinus densiflora community. Quercus mongolica prefered to grow in the medium elevation area that has medium level of total nitrogen, organic matter, and C.E.C. Pinus densiflora, Quercus serrata and Quercus variabilis were found in the low elevation area that has low level of total nitrogen, organic matter, and C.E.C. 3. There seemed to be a certain correlation between nutrients types and Quercus mongolica community. Quercus mongolica and Acer pseudosieboldianum was distributed in the slope area that has medium level of $Mg^{{+}{+}}$, $Ca^{{+}{+}}$, and C.E.C., while Abies nephrolepis, Taxus cuspidata and Pinus koraiensis in the high elevation and ridge area that has low level of $Mg^{{+}{+}}$, $Ca^{{+}{+}}$, and C.E.C. Carpinus laxiflora and Abies holophylla were found in the medium elevation area that has medium level of $Mg^{{+}{+}}$, $Ca^{{+}{+}}$, and C.E.C., while Kalopanax pious, Carpinus cordata and Acer truncatum in the moderately moist and valley area that has high level of $Mg^{{+}{+}}$, $Ca^{{+}{+}}$, and C.E.C. Pinus densiflora and Fraxinus rhynchophylla seemed to prefer the slightly dry, low elevation and ridge area.

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Variation of Functional Materials and Antioxidant Activity as Affected by Cultivation Environment in Pigmented Rice Varieties (재배환경에 따른 유색미의 기능성물질 및 항산화활성 변이)

  • Oh, Sung Hwan;Choi, Kyung-Jin;Kim, Sang Yeol;Seo, Woo Duck;Han, Sang Ik;Cho, Jun Hyun;Song, You Chun;Nam, Min Hee;Lee, Chung Keun;Woo, Sunhee;Lee, Chulwon
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.60 no.2
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    • pp.153-166
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    • 2015
  • Production of high quality pigmented rice contained with high content of anthocyanin, and polyphenol was significantly influenced by cultivation environments like transplanting date and cultivation location. This study was carried out to establish an optimum transplanting date and cultivation region to produce maximum content of anthocyanin, polyphenol and antioxidant activity of pigmented rice varieties (black, red colored). Three transplanting times (May 20, June 5, June 20) and four different sites (Miryang, Uiseong, Sangju, Bonghwa) were evaluated with five pigmented rice cultivars. Anthocyanin and total polyphenol index to average temperature during 30 days after heading (DAH) of black, red pigmented rice varieties showed that anthocyanin and total polyphenol contents were decreased by 10% and 9%, respectively, with increasing average temperature of $1^{\circ}C$. The optimum ripening temperature of the 30 DAH for the production of high anthocyanin and total polyphenol was 22 to $23^{\circ}C$ for early maturity black rice, 21 to $22^{\circ}C$ for mid-late maturity of black and red rices, respectively. On the other hand, an estimated heading date of pigmented rices in return according to the optimum ripening temperature of the 30 DAH was ranged Aug. 11 to 17 for early maturity black rice, Aug. 25 for mid-late maturity black, red rice variety in Jecheon, Aug. 27 to Sep. 2 for early maturity type, Sep. 3 to 6 for mid-late type in Daegu. It seemed that Jecheon, Boeun, Mungyeong, and Yeongju were optimum regions for cultivation of pigmented rices. The estimated sowing date of pigmented rices for high anthocyanin and total polyphenol production based on the optimum heading date was May 18 to 26 for early maturity black rice variety, April 11 for mid-late black, red variety in Jecheon, May 23 to 28 for early type, April 9 to 26 for mid-late type in Boeun, respectively.

Verification of skin dose according to the location of tumor in Tomotherapy (토모테라피 시 종양의 위치에 따른 피부선량 검증)

  • Yoon, Bo Reum;Park, Su Yeon;Park, Byoung Suk;Kim, Jong Sik;Song, Ki Won
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.2
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    • pp.273-280
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    • 2014
  • Purpose : To verify the skin dose in Tomotherapy-based radiation treatment according to the change in tumor locations, skin dose was measured by using Gafchromic EBT3 film and compared with the planned doses to find out the gap between them. Materials and Methods : In this study, to measure the skin dose, I'm RT Phantom(IBA Dosimetry, Germany) was utilized. After obtaining the 2.5mm CT images, tumor locations and skin dose measuring points were set by using Pinnacle(ver 9.2, Philips Medical System, USA). The tumor location was decided to be 5mm and 10mm away from surface of the phantom and center. Considering the attenuation of a Tomo-couch, we ensured a symmetric placement between the ceiling and floor directions of the phantom. The measuring point of skin doses was set to have 3mm and 5mm thickness from the surface. Measurement was done 3 times. By employing TomoHD(TomoHD treatment system, Tomotherapy Inc., Madison, Wisconsin, USA), we devised Tomotherapy plans, measured 3 times by inserting Gafchromic EBT3 film into the phantom and compared the measurement with the skin dose treatment plans. Results : The skin doses in the upper part of the phantom, when the tumor was located in the center, were found to be 7.53 cGy and 7.25 cGy in 5mm and 3mm respectively. If placed 5mm away from the skin in the ceiling direction, doses were 18.06 cGy and 16.89 cGy; if 10mm away, 20.37 cGy and 18.27 cGy, respectively. The skin doses in the lower part of the phantom, when the tumor was located in the center, recorded 8.82 cGy and 8.29 cGy in 5mm and 3mm, each; if located 5mm away from the lower part skin, 21.69 cGy and 19.78 cGy were respectively recorded; and if 10mm away, 20.48 cGy and 19.57 cGy were recorded. If the tumor was placed in the center, skin doses were found to increase by 3.2~17.1% whereas if the tumor is 5mm away from the ceiling part, the figure decreased to 2.8~9.0%. To the Tomo-couch direction, skin doses showed an average increase of 11% or over, compared to the planned treatment. Conclusion : This study found gaps between planned skin doses and actual doses in the Tomotherapy treatment planning. Especially to the Tomo-cocuh direction, skin doses were found to be larger than the planned doses. Thus, during the treatment of tumors near the Tomo-couch, doses will need to be more accurately calculated and more efforts to verify skin doses will be required as well.

Evaluation of Every Other Day - Cone Beam Computed Tomography in Image Guided Radiation Therapy for Prostate Cancer (전립선암의 영상유도방사선치료 시 격일 콘빔 CT 적용의 유용성 평가)

  • Park, Byoung Suk;Ahn, Jong Ho;Kim, Jong Sik;Song, Ki Won
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.2
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    • pp.289-295
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    • 2014
  • Purpose : Cone Beam Computed Tomography(CBCT) in Image Guided Radiation Therapy(IGRT), Set-up error can be reduced but exposure dose of the patient due to CBCT will increase. Through this study, we are to evaluate by making a scenario with the implementation period of CBCT as every other day. Materials and Methods : Of prostate cancer patients, 9 patients who got a Intensity Modulated Radiation Therapy(IMRT) with CBCT in IGRT were analyzed. Based on values corrected by analyzing set-up error by using CBCT every day during actual treatment, we created a scenario that conducts CBCT every other day. After applying set-up error values of the day not performing CBCT in the scenario to the treatment planning system(Pinnacle 9.2, Philips, USA) by moving them from the treatment iso-center during actual treatment, we established re-treatment plan under the same conditions as actual treatment. Based on this, the dose distribution of normal organs and Planning Target Volume(PTV) was compared and analyzed. Results : In the scenario that performs CBCT every other day based on set-up error values when conducting CBCT every day, average X-axis : $0.2{\pm}0.73mm$, Y-axis : $0.1{\pm}0.58mm$, Z-axis : $-1.3{\pm}1.17mm$ difference was shown. This was applied to the treatment planning to establish re-treatment plan and dose distribution was evaluated and as a result, Dmean : -0.17 Gy, D99% : -0.71 Gy of PTV difference was shown in comparison with the result obtained when carrying out CBCT every day. As for normal organs, V66 : 1.55% of rectal wall, V66 : -0.76% of bladder difference was shown. Conclusion : In case of a CBCT perform every other day could reduce exposure dose and additional treatment time. And it is thought to be able to consider the application depending on the condition of the patient because the difference in the dose distribution of normal organs, PTV is not large.