• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2008년도 춘계학술발표회
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• pp.256-257
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• 2008

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2012년도 심포지엄 및 춘계학술발표회
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• pp.121-122
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• 2012

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2012년도 심포지엄 및 춘계학술발표회
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• pp.327-328
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• 2012

• Natural Product Sciences
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• 제17권1호
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• pp.33-37
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• 2011

The plant species reported here are used by traditional healers in Gabon for different ailments such as wounds, malaria, fever, gonorrhea or diarrhea. The aim of this study was to evaluate the antimicrobial activities of 7 plants (Strombosiopsis tetrandra, Tetraberlinia bifoliolata, Dichapetalum barbatum, Guibourtia demeusii, Dacryodes normandii, Manniophytum fulvum, Paropsia grewoides) against different strains of both Methicillin-Resistant Staphylococcus aureus (MRSA) and Salmonella. Disc diffusion was first used to determine the antimicrobial effectiveness of the plants' ethanolic extracts. Then the minimum inhibitory concentrations of the crude extracts of either leaves or stem barks of the 7 plants were determined using broth micro-dilution. The ethanolic plant extracts showed very good activity against both MRSA and Salmonella strains where the MICs ranged from $250\;{\mu}g/ml$ to $1000\;{\mu}g/ml$. The study shows that many of the tested plants used by Gabonese traditional healers have antimicrobial activities and give support to their traditional use.

• 한국자원식물학회지
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• 제22권3호
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• pp.248-265
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• 2009

This study was performed to investigate the flora and plant resources of Mt. Gamak (537.8 m) from April to October 2007. The collected vascular plants were composed of all 478 taxa including cultivated species, and classified into 410 species, 3 subspecies, 61 varieties, and 4 forms of 284 genera under 94 families. Six taxa of the Korean endemic plants and 4 taxa of the rare and endangered plants were also distributed in this mount. Resource plants were categorized into edible 222, pasturing 208, medicinal 183, stainable 134, ornamental 96, timber 20, fiber 6 and industrial 4 taxa, respectively. Floristic geography of the investigated area was regarded as the boundary between middle parts in floristic pattern of the Korean Peninsula.

• 대한본초학회지
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• 제32권2호
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• pp.25-32
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• 2017

Objectives : This study was conducted to investigate candidate materials as anti-inflammatory agent from extracts of Korean medicinal plants in Hwaak mountain. Ligustrum obtusifolium (LO) is a Korea medicinal plants that commonly used for robustness and hemostasis. It has been reported that LO has exhibited anti-ischemic, anti-oxidative, anti-hypolipidemic, anti-tumor and hypoglycemic effects. However, LO has not been previously reported to have an anti-inflammatory effect. Therefore, we have evaluated the anti-inflammatory effects of LO and its underlying molecular mechanisms in LPS-induced RAW 264.7 macrophages. Methods : Cell viability was determined by MTT assay in RAW 264.7 macrophages. Nitric Oxide (NO) was measured with Griess reagent and pro-inflammatory cytokines were detected by ELISA in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. Protein expressions of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and p65 subunit of nuclear $factor-{\kappa}B$ ($NF-{\kappa}B$) were determined by Western blot analysis. Results : Among 15 extracts of Korean medicinal plants tested, Ligustrum obtusifolium (LO) showed the inhibition of NO production without cytotoxicity. LO reduced the expression levels of iNOS and COX-2 proteins in LPS-simulated RAW 264.7 macrophages in dose-dependent manner. Consistent with these data, LO inhibited the productions of $TNF-{\alpha}$, IL-6, and $IL-1{\beta}$ in LPS-simulated RAW 264.7 macrophages. Furthermore, LO attenuated the LPS-induced nuclear translocation of p65 $NF-{\kappa}B$ in RAW 264.7 macrophages involving suppression of $NF-{\kappa}B$ activation. Conclusions : Taken together, these results suggest that the anti-inflammatory effects of LO is associated with regulation of inflammatory mediators via inhibition of $NF-{\kappa}B$ activation in LPS-treated RAW 264.7 macrophages.

• 한국약용작물학회지
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• 제20권6호
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• pp.487-492
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• 2012

Damages of medicinal crops by thrips and identification of thrips species were investigated by periodic surveys on major medicinal crops, Platycodon grandiflorum, Schizandra chinensis, Codonopsis lanceolata, Lycium chinense, Bupleurum falcatum, Ledebouriella seseloides, Angelica gigas, Glycyrrhiza uralensis, Liriope platyphylla, Atractyloides sp., once or twice a month in Suwon, Eumseong, Jecheon, Pyeongchang, Chyungyang from May to October in 2012. Thrips and their damages were found at all of the medicinal crops investigated, mostly occurring at early growing stages of each medicinal crop and causing apical meristem region withered, thereby inhibiting the growth of plants. For species identification of thrips collected from each medicinal crops, DNA from each individual was extracted and ITS2 and COI regions were amplified by PCR. As a result, Frankliniella intonsa, Thrips tabaci, and Megalurothrips distalis have been identified as dominant species on medicinal crops in open field, whereas Frankliniella occidentalis was restricted to Lycium chinense in which protected cultivation. This study suggests that the occurrence of thrips species on medicinal crops seems to be affected by host specificity and environmental factors such as cultivation types.

• 한국약용작물학회지
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• 제8권2호
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• pp.94-101
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• 2000

천연물로부터 새로운 항산화물질을 구명하기 위하여 국내에서 생산된 약용작물 38종을 수집하여 항산화 활성물질을 탐색한 결과 가시오갈피, 구절초, 건강, 목단, 시호, 산수유, 삼백초, 산사, 유근피, 작약, 천궁, 홍화씨, 및 황금등 13종이 항산화 활성이 높은 생약재로 선발되었다. 선발된 13종의 생약재중 홍화씨에 대한 활성물질을 추적, 분리하여 NMR로 물질구조를 동정한 결과 N-feruloylserotonin이 항산화 물질이라는 것을 처음 밝혀냈다. DPPH radical소거 활성에 의한 기존 항산화제인 ${\alpha}$-tocopherol, BHA 및 BHT를 N-feruloylserotonin과 항산화력를 비교한 결과 N-feruloylserotonin이 $6.6{\mu}g/ml$로 활성이 가장 높은 것으로 밝혀졌다.

• Applied Biological Chemistry
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• 제42권3호
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• pp.210-217
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• 1999

전통민속주 제조에 이용되는 부재료 가운데 휘발성 향기성분인 asarone, coumarin, thujone등 식품에 허용기준이 제한된 독성 관련 향기성분을 함유하고 있는 식물성 방향재료 및 약용재료를 확인, 분류하기 위하여 이들의 20% ethanol 추출액으로부터 고상추출(solid phase extraction) 방법을 이용하여 각 성분을 흡착, 용리시킨 후 GC-FID와 GC/MS로 검출, 확인하였다. 조사대상 87종의 식물성재료 중 창포(Acorus asiaticus Nakai), 석창포(Acorus gramineus Solander), 당귀(Angelica gigus Nakai), 백단향(Santalum album) 등 6종에서 asarone이 검출되었으며, coumarin은 소회향(Anethum graveolens), 회향(Foeniculum vulgare Gaertner), 자초(Lithosperum erythrorhizon Siebold et Zuccarinii) 등 22종에서 검출되었다. 한편, 우실(Achyranthes japonica Nakai), 사인(Amomum xanthiodes Wallich), 약쑥(Artemisia asiatia Nakai), 대마자(Cannabis sativa L.)씨, 골담초(Caragana sinica R.), 국화(Chrysanthem morifolium Ramat), 사삼(Codonopsis lanceolata Bentham et flooker), 회향(Foeniculum vulgare Gaertner) 등 24종에서는 thujone을 확인하였다.

• Plant Resources
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• 제6권1호
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• pp.57-75
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• 2003

This study was performed to investigate the flora and plant resources of Mt. Woosanbong (537.8 m) from April to October 2002. The collected vascular plants were composed of all 389 taxa including cultivated species, and classified into 329 species, 2 subspecies, 53 varieties, and 5 forms of 248 genera under 81 families. Six taxa of the Korean endemic plants and 4 taxa of the rare and endangered plants were also distributed in this mount. Resource plants were categorized into edible 181, pasturing 160, medicinal 136, stainable 94, ornamental 77, timber 22, fiber 5 and industrial 4 taxa, respectively. Floristic geography of the investigated area was regarded as the boundary between middle and southern parts in floristic pattern of the Korean Peninsula.