• Publications of The Korean Astronomical Society
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• v.22 no.2
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• pp.43-54
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• 2007

Many gravitational wave detectors are now being built or under operation throughout the world. In particular, LIGO has taken scientific data several times, although current sensitivity is not sufficient to detect the weak signals routinely. However, the sensitivities have been improving steadily over past years so that the real detection will take place in the near future. Data analysis is another important area in detecting the gravitational wave signal. We have carried out the basic research in order to implement data analysis software in Korea@home environment. We first studied the LIGO Science Collaboration Algorithm Library(LAL) software package, and extracted the module that can generate the virtual data of gravitational wave detector. Since burst sources such as merging binaries of neutron stars and black holes are likely to be detected first, we have concentrated on the simulation of such signals. This module can generate pure gravitational wave forms, noise suitable for LIGO, and combination of the signal and noise. In order to detect the gravitational signal embedded in the noisy data, we have written a simple program that employs 'matched filtering' method which is very effective in detecting the signal with known waveform. We found that this method works extremely well.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.84-84
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• 2017

Eleutherococcus senticosus (Siberian ginseng) is an important medicinal tree found in Russian taiga, and northern regions of Korea, Japan, and China. In this study, we analyzed the genome-wide distribution of microsatellites in E. senticosus using developed SSR markers. A total of 711 clones from an SSR-enriched genomic DNA library were sequenced, of which 47 clones (6.6%) were redundant. Of the 664 independent clones, only 12 polymorphic SSR markers were obtained, which also revealed successful amplicons in E. senticosus accessions. Using the developed SSR markers, we estimated genetic diversity and population structure among 131 E. senticosus accessions in Korea and China. The number of alleles ranged from 2 to 11, with an average of 7.4 alleles. The mean values of observed heterozygosity ($H_O$) and expected heterozygosity ($H_E$) were 0.59 and 0.56, respectively. The average polymorphism information content (PIC) was 0.51 in all 131 E. senticosus accessions. E. senticosus accessions in Korea and China showed a close genetic similarity. Significantly low pairwise genetic divergence was observed between the two regions, suggesting a relatively narrow level of genetic basis among E. senticosus accessions. Our results not only provide molecular tools for genetic studies in E. senticosus but are also helpful for conservation and E. senticosus breeding programs.

• Journal of the Korean Data and Information Science Society
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• v.23 no.5
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• pp.949-959
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• 2012

This article is to find the right size of decision trees that performs better for boosting algorithm. First we defined the tree size D as the depth of a decision tree. Then we compared the performance of boosting algorithm with different tree sizes in the experiment. Although it is an usual practice to set the tree size in boosting algorithm to be small, we figured out that the choice of D has a significant influence on the performance of boosting algorithm. Furthermore, we found out that the tree size D need to be sufficiently large for some dataset. The experiment result shows that there exists an optimal D for each dataset and choosing the right size D is important in improving the performance of boosting. We also tried to find the model for estimating the right size D suitable for boosting algorithm, using variables that can explain the nature of a given dataset. The suggested model reveals that the optimal tree size D for a given dataset can be estimated by the error rate of stump tree, the number of classes, the depth of a single tree, and the gini impurity.

• Journal of the Korea Society of Computer and Information
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• v.19 no.10
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• pp.91-97
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• 2014

In this paper, we design and implement a mobile game based on windows phone platform. Visual Studio and the Windows Mobile software development kit(SDK) and developer tool kits (DTK) make it possible to create software for the Windows Mobile platform in Visual C#. Also The XNA Framework is the set of .NET libraries that developers will code against to build games. XNA Framework support PC and XBOX and a ZUNE HD multiplex platform environment and 2D and 3D games provides the necessary functions to a development. XNA Framework is to make it easier to develop games because the codes which are succeeded creates with automatic, implements a game development relation resource and the game logic. The key idea of our game is that we use shooting and ranking system to raise fun.

• Journal of Nutrition and Health
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• v.54 no.5
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• pp.515-533
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• 2021

Purpose: A systematic review and meta-analysis of nutrition educational intervention studies was performed to assess the association between nutrition education intervention and fruit & vegetable (F&V) preferences and nutrition knowledge in preschool children. Methods: The relevant studies of nutrition education intervention and F&V preferences and nutrition knowledge published from January 2000 to June 2020 were located using PubMed, Web of Science, Cochrane Library, Research Information Sharing Service, Korean Studies Information Service System databases, and lists of references. A random-effects meta-analysis was conducted to estimate the standardized mean difference with a 95% confidence interval (CI). Subgroup analyses were performed to identify the association between nutrition education and F&V preferences and nutrition knowledge. Results: The results show that the effect sizes (ES) of F&V preferences and nutrition knowledge of preschool children were 0.31(95% CI, 0.23, 0.39), and 1.69(95% CI, 1.27, 2.12), respectively. The result of subgroup analysis, nutrition education focused on F&V (F&V preferences, ES: 0.32; nutrition knowledge, ES: 2.09) presented a slightly larger effect than general nutrition education (F&V preferences, ES: 0.26; nutrition knowledge, ES: 1.62). As for the type of exposure to F&V, direct exposure education (F&V preferences, ES: 0.40) had a greater effect than indirect exposure (F&V preferences, ES: 0.26). This meta-analysis showed that nutrition education intervention had positive effects on the F&V preferences and nutrition knowledge in preschool children. Conclusion: In conclusion, from the meta-analysis and subsequent subgroup analysis, we found that varied types of nutrition education intervention had varying effects on F&V preferences and nutrition knowledge in preschool children.

• The Journal of Sustainable Design and Educational Environment Research
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• v.9 no.3
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• pp.49-58
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• 2010

The Ministry of educational science and technology is about to conduct its 7th &8th curriculum. However, there are some problems in achieving its goals under the current class model system in both educational and architectural. This study finds the characteristics of the arrangements and architectural planning in the departmental system - designed high schools. As a result, the arrangement was tend to be 'overall type' or 'central type' depending on the teaching-learning efficiency. Liberal arts and science&technology groups were placed close, and foreign languages and general cultural studies were arranged close as well. Importantly, there were supporting facilities such as a gymnasium, a cafeteria, a library, a computer lab, and an all-purpose-room, and this arrangement provided convenience. It is for the better learning effect and the high efficiency. It is worthy noticing that the placement and formation of individual or study space is regarded importantly. In flow planning, it seemed that it was designed to reduce the users' movement to a minimum. However, there are still some problems compared to Japan or the States, who already has an established departmental system. I think that the government should enforce its necessity of planning to schools, relevant divisions, or architects to bring it up. Furthermore, it is urgently needed a practical and future-oriented study that can forecast any changes in architectural spaces within the ever-changing teaching and learning environment in the information-oriented society.

• Journal of Microbiology and Biotechnology
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• v.32 no.11
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• pp.1471-1478
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• 2022

2'-Fucosyllactose (2'-FL), the most abundant fucosylated oligosaccharide in human milk, has multiple beneficial effects on human health. However, its biosynthesis by metabolically engineered Escherichia coli is often hampered owing to the insolubility and instability of α-1,2-fucosyltransferase (the rate-limiting enzyme). In this study, we aimed to enhance 2'-FL production by increasing the expression of soluble α-1,2-fucosyltransferase from Helicobacter pylori (FucT2). Because structural information regarding FucT2 has not been unveiled, we decided to improve the expression of soluble FucT2 in E. coli via directed evolution using a protein solubility biosensor that links protein solubility to antimicrobial resistance. For such a system to be viable, the activity of kanamycin resistance protein (Kan^R) should be dependent on FucT2 solubility. Kan^R was fused to the C-terminus of mutant libraries of FucT2, which were generated using a combination of error-prone PCR and DNA shuffling. Notably, one round of the directed evolution process, which consisted of mutant library generation and selection based on kanamycin resistance, resulted in a significant increase in the expression level of soluble FucT2. As a result, a batch fermentation with the ΔL M15 pBCGW strain, expressing the FucT2 mutant (F#1-5) isolated from the first round of the directed evolution process, resulted in the production of 0.31 g/l 2'-FL with a yield of 0.22 g 2'-FL/g lactose, showing 1.72- and 1.51-fold increase in the titer and yield, respectively, compared to those of the control strain. The simple and powerful method developed in this study could be applied to enhance the solubility of other unstable enzymes.

• Journal of The Korean Association For Science Education
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• v.29 no.5
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• pp.552-563
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• 2009

The purpose of this study is to investigate the students' perception of the learning support system of Korea Science Academy and to propose improvements to it. The impact of the science learning support system on 129 gifted students in Korea Science Academy (KSA) was estimated by using Likert-type items and the multiple-choice method approach for more comprehensive evaluation. The results of our investigation are as follows: First, the learning support system of KSA appears globally useful to the students. The list of educational usefulness to the students comprises, in the decreasing order of utility, classroom work, Internet, lab activities, reading rooms, library, research meetings and clubs, academic advisors (AA), SAF (Science Academy Fair), e-learning system, and finally colloquia by invited lecturers. Second, what the gifted students hope for in the realm of learning support from KSA are learning guides by subject teachers, presentation skill program, the constructions of on/off-line learning communities, etc. It seems that the results of this study would be helpful in improving the learning support system, and will provide useful information for planning the direction of future science-gifted education programs at the high-school level.

• Journal of Life Science
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• v.18 no.11
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• pp.1507-1512
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• 2008

In spite of long research period for Salmonella typhi, little information is known about the pathogenesis mechanism of human typhoid fever caused by S. typhi due to lack of infection model in animals. A wild-type of S. typhi Ty2 strain requires cysteine to grow on minimal media. We hypothesized that this cysteine requirement may restrict colonization of S. typhi in animals during infection process. Among the S. typhi strains carrying Salmonella typhimurium genomic library, we have isolated three S. typhi transformants growing on minimal media without cysteine. Although there were three ORFs in DNA of pBP71, the STM1490 ORF complemented cysteine auxotrophy of S. typhi. Analysis of the deduced amino acid sequence of the STM1490 homolog in S. typhi revealed that there are differences in two amino acids. Plasmids containing amino acid substitutions in STM1490 supported S. typhi growth on minimal media without cysteine, indicating irrelevance of these two amino acids to STM1490 function. These results tells us that there are other factors or systems involved in cysteine requirement of S. typhi.