• Title/Summary/Keyword: Korean Society of Ginseng

Search Result 6,536, Processing Time 0.032 seconds

Overexpression of PgSQS1 Increases Ginsenoside Production and Negatively Affects Ginseng Growth Rate in Panax ginseng

  • Shim, Ju-Sun;Lee, Ok-Ran;Kim, Yu-Jin;Lee, Jung-Hye;Kim, Ju-Han;Jung, Dae-Young;In, Jun-Gyo;Lee, Beom-Soo;Yang, Deok-Chun
    • Journal of Ginseng Research
    • /
    • v.34 no.2
    • /
    • pp.98-103
    • /
    • 2010
  • The medicinal plant Panax ginseng (P. ginseng) contains various phytosterols and bioactive triterpene saponins (ginsenosides). Squalene synthase catalyzes the first committed step in ginsenoside biosynthesis. Transgenic plants of P. ginseng were generated by introducing the squalene synthase gene derived from P. ginseng. Adventitious roots of the transgenic ginseng grew best in B5 medium, and 2 g of inoculum secured an optimal growth rate. Two phytohormones, indolebutyric acid and 1-naphtalene acetic acid, increased root growth and decreased ginsenoside production. Treatment with two selected elicitors, chitosan and jasmonic acid, and a precursor of the isoprenoid pathway, mevalonic acid, enhanced ginsenoside production and retarded ginseng growth rate.

Comparative Cytotoxic Activities of Various Ginsengs on Human Cancer Cell Lines

  • Sung Ryong Ko;You
    • Journal of Ginseng Research
    • /
    • v.22 no.1
    • /
    • pp.18-21
    • /
    • 1998
  • Comparative cytotoxic activities of petroleum ether soluble fraction from various ginsengs of Panax species were evaluated using A549 (human lung adenocarcinoma) and SK-OV-3(human ovary carcinoma) cancer cell lines. Korean red ginseng, Korean white ginseng, American ginseng and Canadian ginseng were found to show more potent cytotoxicitles on A549 and SK-OV-3 cell lines than Chinese red ginseng, Japanese red ginseng and Sanchi ginseng. It is noteworthy that especially, red ginseng prepared from the root of Panax ginseng cultivated in Korea shows relatively stronger cytotoxic activities than those cultivated in China and Japan.

  • PDF