• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.6
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• pp.662-667
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• 2014

The purpose of this clinical study is to develop structured clinical trial protocol and guideline for improvement of safety, useful and effective of pulse diagnosis devices. As a first step, papers on pulse diagnosis and pulse diagnosis devices from 2001 and 2013 were systematically reviewed. In the next step, we have collected the opinions from the specialists, companies, and statistician in pulse diagnosis to evaluate the current condition, the state and problem of domestic clinical trial cases of pulse diagnosis device. And we have to created protocol and case report form (CRF) in regards to site condition and characteristics of pulse diagnosis devices, and showed the guideline of eligibility criteria, operation process, investigation items, evaluation items and so on. This clinical protocol will become a basic information for a researcher in designing or performing a clinical study of pulse diagnosis devices, and be used as a useful material during acquisition of good clinical data. Furthermore, we hope to enhance the invigoration of pulse diagnosis clinical trials and the performance improvement of pulse diagnosis devices.

• Korean Journal of Oriental Medicine
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• v.2 no.1
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• pp.381-401
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• 1996

The diagnostic requirements were suggested and explained regarding the systems of differentiation of syptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : -differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to reletive excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) -differentiation of diseases according to pathological changes of the viscera and their interrelation(臟腑辨證) -analysing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following odor : another name(異名), notion of diagnosis parrern(證候槪念), index of differentiation of syptoms and sings(辨證指標), the main point of diagnosis(診斷要點), analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a wayof curing a diseases(治法), prescription(處方) , herbs in common use(常用藥物), dieases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.3
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• pp.528-531
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• 2002

In Traditional Oriental Medicine, there has been a growing needs for computerized diagnosis expert system, which can implement pre-diagnosis and correct the errors of practitioners. Therefore, we developed the expert system (KHU-PIPE : Kyung Hee University - Pattern Identification and Prescription Expert) for diagnosis and treatment. It has three characteristics as following. First. this system has the knowledge base which modified the standardized data designed by Chinese government during 1980s. Second, it provides the objective and standardized diagnosis as the results of pattern identification and their appropriate prescriptions for treatment. Third, it is applied to both LAN system and internet. Furthermore, it can be used as an educational methods for the practices of pattern identification and prescription, and provide the objective criteria for clinical studies and promote the Traditional Oriental Medicine as an evidence-based medicine.

• Journal of Korean Medicine for Obesity Research
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• v.9 no.1
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• pp.37-44
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• 2009

The study was to investigate the distribution for the diagnosis of pattern identification questionnaire and agreement rate between diagnosis of pattern identification based on obesity pattern identification questionnaire and the clinical diagnosis of pattern' identification by medical specialist. The distribution for the diagnosis of pattern identification based on obesity pattern identification questionnaire was shown in order of stagnation of liver Gi, retention of undigested food, deficiency of Yang at scale of 5, 3, 2 score and the diagnosis rate of single pattern identification at scale of 5, 3, 2 score was 89.96%, 79.33%, 54.64%, respectively the agreement rate between the diagnosis of pattern identification based on obesity pattern identification questionnaire and the clinical diagnosis of pattern identification by medical specialist was 0.1013. Therefore, the complementary management in CRF questionnaires with consultation from experts and the study for score difference of pattern identification will improve the accuracy and agreement rate, which will will be helpful for pattern identification of obesity by clinical experts.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.1
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• pp.91-98
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• 2014

Objective : This study aimed to assessment for concordance rate in pattern analysis between pattern diagnosis of KiFDA on allergic rhinitis in 2008 and doctor of Korean medicine. Methods : Data were obtained from 35 patients with allergic rhinitis(AR). They were asked to perform the questionnaires and had been interviewed by specialist of Korean Medicine. For correlation analysis, we used Cohen's Kappa. Results : The pattern diagnosis was done only 15 patients(42.9%). Correlation between pattern diagnosis of questionnaires and specialist showed 0.2105 in Kappa and 0.1993 in weighed Kappa. Conclusions : The result may provide the basis of modification in Pattern Diagnosis of KiFDA on allergic rhinitis in 2008.

• Tuberculosis and Respiratory Diseases
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• v.86 no.3
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• pp.176-182
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• 2023

Since the introduction of low-dose computed tomography (CT) screening for patients at high risk of lung cancer, the detection rate of suspicious lung cancer has increased. In addition, there have been many advances in therapeutics targeting oncogenic drivers in non-small cell lung cancer. Therefore, accurate pathological diagnosis of lung cancer, including molecular diagnosis, is increasingly important. This review examines the problems in the pathological diagnosis of suspected lung cancer. For successful pathological diagnosis of lung cancer, clinicians should determine the appropriate modality of the diagnostic procedure, considering individual patient characteristics, CT findings, and the possibility of complications. Furthermore, clinicians should make efforts to obtain a sufficient amount of tissue sample using non- or less-invasive procedures for pathological diagnosis and biomarker analysis.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.3
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• pp.240-245
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• 2015

Pulse diagnosis, the most popular diagnostic tool in traditional Korean medicine, had had many forms but had been fixed on using wrist pulse and placing internal organs on Cun, Guan and Chi(寸 關 尺). Wang Shuhe(王叔和) suggested placing six viscera(六腑) on Cun, Guan and Chi based on relationship between external and internal meridian vessel, and Zhang Jiebin(張介賓) criticized his suggestion and insisted that pulse diagnosis should be based on the organ system. But the origin of pulse diagnosis which can be found in "(Huangdi's) Internal Classic(黃帝內經)" is a tool mainly for diagnosis of not internal organ system but meridian system. Most of material about pulse diagnosis after Ming dynasty(明代) reinterpreted pulse diagnosis in the aspect of organ system, So there has to be additional discussion about it.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.1
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• pp.202-208
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• 2006

The goal of this study is to develop knowledge representation method for the construction and evaluation of ontology for diagnosis in oriental medicine. To develop the expert system for decision making on diagnosis and treatment, the systematic and structural knowledge which can be processible in EMR(Electronic Medical Record) must be precedent, and the Computational Process which control the system as well. This study set up an ontology as a trial model to represent the oriental medical knowledge into the machine processible one. Protege 2.1 has been used to build the ontology, and the serialization format of our ontology is the XML document based on OWL. The components of oriental medical diagnosis was arranged with the combination of symptoms which belong to the certain symptom patterns. Then natural language which expresses the oriental medical diagnosis components were converted into the logical sentence, and individual characteristic symptoms into each values of specific properties. In addition to the study, the diagnosis software for oriental medicine was developed and it used the ontology which we developed. Sequently, we tested the software to confirm the appropriateness of ontology. The result of the test shows that diagnostic questions are automatically formulated according to the diagnosis components of this ontology and that as such diagnostic results are induced. Therefore, the ontology system in this study will be efficient to develop the diagnosis program and useful as a tool for doctors to make decision. But, it is not recommendable to apply the system to the clinical environment until the clear diagnosis standards are introduced, and the more reliable diagnosis program can be developed based on the more appropriate ontology mentioned above.

• Korean Journal of Oriental Medicine
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• v.12 no.2 s.17
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• pp.103-113
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• 2006

Objectives we intended to know how much did it relate with the results between the instruments of diagnosis by using methods of three factors - QSCCII, PSSC(Phonetic System for Sasang Constitution)-2004, and body measurement which are usually used in diagnosing the Sasang Constitution in clinics Methods We diagnosed Sasang constitution through QSCCII, PSSC(Phonetic System for Sasang Constitution)-2004, Body measurement as a dignosis factors and we used Kappa coefficient to estimate simularity between diagnosis factors, and SPSS 12.0K to analyze data Results and conchusions 1. The orders of agreement statistics are different in the currency of Sasang Constitution diagnosis, Soeum-in was highest and Taeum-in lowest in the the fricency of Sasang Conctitution Diagnosis in the QSCCII, Soeum-in was highest Soyang-in lowest in the PSSC and Taeum-in highest, Soyang-in lowest in the body measurement so, we analogized incorrection in Sasang Constitution Diagnosis 2. Among 443 subjects, 156 (35.3%) had same dignosis in three Sasang Constitution factors. It means agreement statistics among factors of diagnosis are very low, so it is absolutely nessessary to research connection among those, especially Soyang-in part 3. Totally, it is not robust to apply these factors on Sasang Constitution diagnosis, especially agreement statistics between two kinds of Sasang Constitution diagnosis as $0.358{\sim}0.380$. However, we can have a possibility the more we use Sasang Constitution dignosis factors, the higher the agreement statistics is, through the ascending of agreement statistics as $0.526{\sim}0.592$, among three kinds of Sasang Constitution diagnosis To evaluate accuracy of Sasang Constitution diagnosis, it is nessessary to collect data from the subjects who are dignosed through the evidences such as herb medicine, disease and normal symption observation, etc. Using these data, we have to evaluate correction of seperated Sasang Constitution diagnosis methods and to connect those.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.4
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• pp.745-750
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• 2009

The goal of this study is to examine on reasoning and search for construction of diagnosis ontology as a knowledge base of diagnosis expert system in oriental medicine. Expert system is a field of artificial intelligence. It is a system to acquire information with diverse reasoning methods after putting expert's knowledge in computer systematically. A typical model of expert system consists of knowledge base and reasoning & explanatory structure offering conclusion with the knowledge. To apply ontology as knowledge base to expert system practically, consideration on reasoning and search should be together. Therefore, this study compared and examined reasoning, search with diagnosis process in oriental medicine. Reasoning is divided into Rule-based reasoning and Case-based reasoning. The former is divided into Forward chaining and Backward chaining. Because of characteristics of diagnosis, sometimes Forward chaining or backward chaining are required. Therefore, there are a lot of cases that Hybrid chaining is effective. Case-based reasoning is a method to settle a problem in the present by comparing with the past cases. Therefore, it is suitable to diagnosis fields with abundant cases. Search is sorted into Breadth-first search, Depth-first search and Best-first search, which have respectively merits and demerits. To construct diagnosis ontology to be applied to practical expert system, reasoning and search to reflect diagnosis process and characteristics should be considered.