• Herbal Formula Science
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• v.29 no.4
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• pp.311-319
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• 2021

Objectives: The aim of this study is to present one case report on the treatment of psoriasis. Methods: We did retrospective study for one psoriasis patient who had been treated by herbal medicine and acupuncture for more than one year. The patient was treated with Bojungikgi-tang hap Gamisoyo-san, Yukmijihuang-tang hap Gamisoyo-san, Saengmaek-san hap Gamisoyo-san, Gamisoyo-san hap Samul-tang and Gamisoyo-san hap Yukmijihwang-tang. Evaluation was done by PASI score and pictures. Results: After the treatment, the patient showed improvements in PASI. PASI of the patient changed from 28.2 to 0. Conclusions: This study suggests the clinical use of Korean medical treatment in systemic psoriasis.

• Journal of Physiology & Pathology in Korean Medicine
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• v.36 no.6
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• pp.242-246
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• 2022

The purpose of this study is to report on the clinical improvement of a patient treated with Korean medicine for Post COVID-19 syndrome. A 52-year-old male patient with headache and chronic fatigue was diagnosed with post-acute COVID-19 syndrome. He had clinical symptoms such as headache, sweating, fatigue, and insomnia and was treated with acupuncture and herbal medicines such as Sasammaekmoondong-tang. To assess the treatment outcomes, the authors used the Fatigue Severity Scale (FSS) and the Numeral Rating Scale (NRS). Following treatment, fatigue improved, with the FSS score dropping from 48 at the first visit to 18 at the final visit, and clinical symptoms such as headache and insomnia disappeared. According to the findings of this study, Korean Medicine could be used in the clinic to treat post-COVID-19 complications.

• The Journal of Internal Korean Medicine
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• v.42 no.5
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• pp.982-990
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• 2021

Objectives: The aim of this study was to report the effectiveness of Korean medicine treatment for a patient with lateral medullary infarction who presented with central dizziness and hypoesthesia. Methods: The patient was treated with Korean medicine treatment, including acupuncture, moxibustion, and herbal medicine. We measured the progress of the case using the Numerical Rating Scale (NRS). Results: After the treatment, the NRS scores for dizziness and hypoesthesia decreased. Conclusions: This study suggests that Korean medicine treatment might be effective for lateral medullary infarction in patients who present with central dizziness and hypoesthesia.

• Herbal Formula Science
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• v.31 no.4
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• pp.265-281
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• 2023

Objectives : Ukgan-san plus Citri Pericarpium and Pinelliae Rhizoma (UCP) is used as a traditional herbal formula in Korea and Japan for treatment of fever, fever-induced convulsions, and liver dysfunction and so on. In this study, we investigated the cytoprotective effect and underlying mechanism of UCP against oxidative stress induced by cotreatment of arachidonic acid (AA) and iron. Methods : To evaluate the hepatoprotective effects of UCP against AA + iron-induced oxidative stress in HepG2 cell, cell viability and changes on apoptosis-related proteins were assessed by MTT and immunoblot analyses. The changes in intracellular reactive oxygen species (ROS), glutathione (GSH), and mitochondrial membrane permeability (MMP) were investigated against to the oxidative stress. Furthermore, to verify underlying molecular mechanism, NF-E2-related factor 2 (Nrf2) and its downstream target genes were examined by immunoblot analysis. Results : Treatment of UCP increased the cell viability and altered the expression levels of apoptosis-related proteins such as PARP, caspase-9, caspase-3, Bcl-2. UCP also inhibited the GSH depletion, excessive ROS production and mitochondrial dysfunction induced by AA + iron. In addition, the Nrf2 and the Nrf2 target genes activation were increased by UCP. Conclusions : These results indicated that UCP has the ability to protect against oxidative stress-induced hepatocyte damage, which may be mediated with Nrf2 pathway.

• The Journal of Internal Korean Medicine
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• v.43 no.4
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• pp.761-768
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• 2022

The purpose of this case report was to document the efficacy of Korean medicine as a treatment for Ophthalmoplegia of Miller-Fisher Syndrome. A 57-year-old male patient was treated with acupuncture, electropuncture, pharmacopuncture, and cupping treatments for 2 months. Symptom changes were evaluated using the Scott and Kraft score, photographs of eyeball movement, and the Yanagihara score. Korean medicine treatment significantly improved the eye movements, ncreased the Scott and Kraft score from -4 to 0, and improved the Yanagihara score from 20 to 32. Korean medicine treatment could effectively and quickly treat Ophthalmoplegia of Miller-Fisher Syndrome.

• The Journal of the Society of Stroke on Korean Medicine
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• v.9 no.1
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• pp.33-39
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• 2008

Ataxia and vertigo are frequent clinical findings in cerebellar infarction patients. In severe cases, they cannot achieve normal activity in daily life. A 65-year-old man was admitted with ataxia and vertigo diagnosed as acute cerebellar infarction. We prescribed for Chukdam-tang to treat the phlegm disease. After this treatment, ataxia and vertigo improved. We suggest Chukdam-tang is significantly effective on the treatment of cerebellar infarction.

• The Journal of Korean Medical History
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• v.36 no.1
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• pp.89-98
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• 2023

This study aimed to review trends in Korean medical education research from 2003 to 2022. A total of 60 studies were identified, with an increasing trend in publication numbers. The research topics covered various aspects of Korean medicine education, including curriculum, basic science, clinical science, teaching methods, history, and international comparisons. Text mining analysis revealed "Curriculum", "Satisfaction" and "Clinical" to be frequent terms. The study suggests that Korean medicine education research should continue to develop, given its broad scope and growing interest.

• Journal of Physiology & Pathology in Korean Medicine
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• v.32 no.6
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• pp.418-421
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• 2018

The purpose of this study was to evaluate the changes of liver function test before and after treatment in patients admitted to Korean medicine hospital. We checked liver function test level (aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, total bilirubin, direct bilirubin) of 147 patient who admitted in Korean medicine hospital from July 1, 2015 to June 30, 2018. The subjects were selected those who took herbal medicine continuously during the admission period and who performed liver function test on admission and before discharge. And the subjects were excluded those who had a history of liver and biliary disease at the time of admission or who took hepatoprotectants. Aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase significantly decreased compared with the values of admission(p<0.05), but total bilirubin and direct bilirubin were not significantly changed(p>0.05). On admission 31 patients(21.1%) had abnormal liver function and 6 patients(4.1%) had liver injury while 19 patients(12.9%) had abnormal liver function and 6 patients(4.1%) showed liver injury before discharge. This study suggests that herbal medicine may not injure liver function.

• The Journal of Internal Korean Medicine
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• v.42 no.5
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• pp.1045-1053
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• 2021

Objectives: This study investigated the effectiveness of acupuncture and herbal medicine (Gami-banhabakchulchunma-tang) for post-stroke visual impairment. Methods: A 79-year-old male with headache, dizziness, visual field defects, and blurred vision caused by a posterior cerebral infarction was treated with acupuncture and Gami-banhabakchulchunma-tang for three months. We used the Numerical Rating Scale (NRS) for each symptom and measured the patient's eye-movement range. Results: Following treatment, the NRS score for headache decreased from 5 to 0, and for dizziness and blurred vision, it decreased from 5 to 1. The NRS score for visual field defects decreased from 5 to 2. The range of the patient's left and right eye movements both improved, and no adverse side effects were observed during the admission period. Conclusions: Korean medical treatment with acupuncture and herbal medicine (Gami-banhabakchulchunma-tang) could effectively treat post-stoke visual impairment.

• The Journal of the Society of Stroke on Korean Medicine
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• v.13 no.1
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• pp.24-32
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• 2012

Object : The purpose of this study is to observe the correlation between change in pattern identification symptoms and scandinavian stroke scale in ischemic stroke patient who had receive traditional Korean medical treatment and conservative treatment. Methods : 43 subjects were recruited from patients with ischemic stroke within 30 days of onset. We chose the subjects who had at least one follow up session and had checked the score between last follow up session and first session in pattern identification and scandinavian stroke scale. We also assessed the correlation between pattern identification and scandinavian stroke scale. Results : There were significant negative correlation between pattern identification and scandinavian stroke scale in Fire-heat pattern and positive correlation in Dampness-phlegm pattern. Conclusions : This study provides evidence that collaborative treatment maybe effective in improving neurologic symptoms in ischemic stroke patients diagnosed as Fire-heat pattern. Further studies with larger scale and longer observation period, more neurologicscales scales, control group would be required.