• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.6
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• pp.683-693
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• 2009

This study was designed to investigate the effect of dandelion juice supplementation on attenuation of oxidative stress and hangover after drinking alcohol in healthy college male students. This human trial was conducted by two phase cross over design with two weeks wash out period. The subjects (age $24{\sim}28$ years) were volunteers who had more than 72 g of ethanol drinking capacity. Dandelion group was given dandelion juice 220 mL daily for 7 days. Biochemical markers were determined in blood samples taken at 0 and 150 minutes after administration 72 g of alcohol. The levels of plasma glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, lactate dehydrogenase and bilirubin, the indicators of liver cell damage, were not significantly different between groups. No significant differences in lymphocyte DNA damage level between groups was observed. However, plasma acetaldehyde dehydrogenase (ALDH) and high density lipoprotein cholesterol levels were significantly (p<0.01) increased in dandelion supplemented group compared to that of control group. Furthermore, activities and protein expressions of glutathione-reductase and catalase of erythrocytes were significantly elevated in dandelion supplemented group compared to that of control group. From the above results, it is concluded that dandelion juice supplementation can reduce oxidative stress and hangover syndrome through the elevation of ALDH and antioxidative enzyme system in healthy male adults.

• Journal of Preventive Medicine and Public Health
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• v.44 no.1
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• pp.56-64
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• 2011

Objectives: The purpose of this study was to estimate the prevalence and correlated factors of high myopia in 19 year-old men in Southeast Korea. Methods: This retrospective study was based on the medical checkup data of conscription during 2005. The study subjects were 19 years old men in Busan, Ulsan and Gyeongsangnam-do. The health checkup data of the conscripts consisted of noncycloplegic autorefraction test, the biometric data and social factors. To analyze the social and biometric effects, we classified the biometric factors into 4 or 5 groups and the social factors into 3 groups. High myopia was defined as a spherical equivalent of under -6.0 diopter. Data analysis was performed using the chi square test for trends and multiple logistic regression analysis. The SAS(version 9.1) program was used for all the analyses. Results: The prevalence of high myopia was 12.39% (6256 / 50 508). The factors correlated with high myopia were the residence area (OR, 2.07; 95% CI, 1.77 to 2.4 for small city; OR, 2.01; 95% CI, 1.72 to 2.34 for metropolis; the reference group was rural area), academic achievement (OR, 1.43; 95% CI, 1.34 to 1.53 for students of 4-and 6-year-course university; the reference group was high school graduates & under) and blood pressure (OR, 1.54; 95% CI, 1.10 to 2.16 for hypertension; OR, 1.09; 95% CI, 1.02 to 1.17 for prehypertension; OR, 1.10; 95% CI, 1.01 to 1.20 for hypotension; the reference group was normal blood pressure). Conclusions: More than one tenth of the young men were high myopia as one of the risk factor for visual loss. Further studies on high myopia and its complications are needed to improve eye health in Southeast Korea.

• 대한공업교육학회지
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• v.32 no.2
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• pp.47-68
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• 2007

The purpose of this research was on the operation activation for specialized high schools in Chungcheongbuk-do, and conducted a survey of chief teachers of Practical Art Subject and heads of each subjects in 32 specialized high schools in district about the system reform of vocational high school, promotion of characterization for each subject, modification of curriculum, reinforcement of direction guide, of which results were analyzed. Also, another survey of small and middle businesses was conducted to investigate the demand for human resources for industrial businesses in Chungcheongbuk-do and specialized abilities required by companies. Through the study, the reform of operation activation for specialized high schools in Chungcheongbuk-do were suggested as follows. First, Specialized high schools should more focus on educating application of a computer and the basic abilities in foreign language at the request of industry. Second, If more than 80% of vocational high school graduates go to junior colleges or universities, specialized high schools should reform their operation like general high schools. Third, Specialized high schools should expand the operation of customized curriculum for neighboring industry to raise employment rate. Fourth, Specialized high schools in Chungcheongbuk-do should reform their courses which can provide students with fundamental knowledge to work in industry related to BT and IT, as Osong medical complex and Ochang IT industrial complex are expanding gradually. Fifth, Employees in companies should be applied as guest teachers, and the principal should have a right to autonomy to operate their own curriculum. Sixth, 5 years rotation system for public schools should be revised to more than 10 years rotation system for special subjects in specialized high schools. Therefore, teachers will have ownership of the school by the revised system.

• Journal of Preventive Medicine and Public Health
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• v.28 no.3 s.51
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• pp.678-689
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• 1995

Chromium is one of the representative toxic substance by occupational exposure which damage the mucosa of respiratory tract including nasal septal perforation. The aim of this study is to evaluate the effect of chromium exposure on olfactory function and to obtain the fundamental information about chromium exposure. The authors performed olfactory function test, laboratory tests and questionnaire interview on the subject of three groups, that is, two exposed groups and one nonexposed group from May 1 to June 30, 1994. Exposed group 1 was 15 male workers without nasal septal perforation, exposed group 2 was 15 male workers with nasal septal perforation among 103 workers in 22 chromium plating factories, and nonexposed group was 15 male medical students. The gathered informations were histories of chromium exposure, habits of smoking and alcohol drinking, the concentrations of chromium in serum and urine, and asparate aminotransferase(AST), alanine aminotransferase(ALT), gamma-glutamyl transferase, etc. Olfactory function was checked by T and T olfectometer using phenyl ethyl alcohol(material A), methyl cyclopentenolone(material B), iso-valeric acid(material C), $\gamma$-undecalactone(material D), skatole(material E) and the results were expressed by detection threshold(DT) and recognition threshold(RT). There was a significant difference between exposed groups and nonexposed group in A, B, C, D, E substances by DT and in A, B, C, D substances by RT(P<0.01). The degree of olfactory dysfunction was highest in the exposed group 2 and lowest in the nonexposed group in all five substances by DT and it was same in A B, D substances RT and the difference of RT and DT. As summary, olfactory dysfunction by chromium exposure was recognized and the degree of olfactory dysfunction was higher in the exposed group with nasal septal perforation. Therefore, it would be helpful to apply olfactory function test for the early detection of olfactory dysfunction, and this test would be considered as the basic tool within workers' compensation system.

• Journal of agricultural medicine and community health
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• v.21 no.2
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• pp.221-230
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• 1996

This study was purposed to develop the fluoride mouthrinsing project through the public health system in a rural area. This project was performed under the management of the public health dentist for the 3rd grade students selected from the 5 primary schools at Goksunggun in Chonnam area. Fluoride mouthrinsing was executed with 0.2% neutral sodium fluoride solution once a week. After 1 year's fluoride mouthrinsing project, DMFT index, DMF rate frequencies of toothbrushing, simplified oral hygiene index, and the responses to fluoride mouthrinsing project of the school children participated were examined. The results obtained from this study were as follows: 1. The fluoride mouthrinsing project for school children was performed average 10 times a year by the public health dentist. They were relatively little active to perform this project. 2. There was no significant difference in the increasement of DMFT index and DMF rate during 1 year between control and fluoride mouthrinsing group. 3. Control group was increased higher than fluoride mouthrinsing group in simplified oral hygiene index. 4. Toothbrushing frequencies increased in both groups. 5. 80.4% of school children participated in fluoride mouthrinsing project was responded to like it, and 78.2% among them was responded the project to be beneficial for their dental health. 6. 39.2% of school children was responded to have water-like taste for fluoride solution. But 34.0% of them was done to have strange taste. On consideration of above findings, this fluoride mouthrinsing project was not well performed by the public health dentists and also the oral health status of school children participated was not significantly improved by this project. Therefore, to perform continually this project well, it was recommended that this project should be performed by other person such as dental hygienist rather than public health dentist.

• Anxiety and mood
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• v.5 no.1
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• pp.21-28
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• 2009

Objective : Using patterns of change in heart rate variability (HRV), we investigated the effects of stress exposure and type of anger expression on cardiovascular diseases. Methods : Eighty-nine medical students were evaluated by STAXI-K, BDI, BAI, and measured HRV. According to the scores of anger expression questions in STAXI-K, objects are comparted to three groups. Each group is compared with others on the levels of depression, anxiety and HRV. Additionally objects are divided into two groups of functional anger expression group and dysfunctional anger expression group, and each group also divided into two groups, depending on the exposure of stressful situation or not. Members who took part in the stress exposure groups, they've got a serial arithmetic process for five minutes. We surveyed patterns of HRV in 4 each groups and estimated interactions between existence of stressful situation or type of anger expression and HRV. Results : Irrespective of stress manipulation, the dysfunctional anger expression group showed a marked increase in the LF/HF ratio in comparison to the functional anger expression group. Also, under conditions of stress manipulation, the stress exposure group exhibited a relatively increased level of TP. It can't be discriminated any correlations between stress manipulation and type of anger expression. Conclusion : Both of them, exposure to the stressful situation and type of anger expression, have influence on cardiovascular diseases. By controlling anger and way of express that, it is possible to diminish the incidence of cardiovascular diseases.

• Journal of Technologic Dentistry
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• v.28 no.1
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• pp.161-176
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• 2006

The purpose of this study was to evaluate smoking of dental technicians in 2005, and we have distributed questionnaires about smoking in 2005-KDTA general meeting and analyzed them. All 555 respondents who attended KDTA general meeting were selected by random sampling. However we dismissed 41 because of invalidness, so we got 504 people. Therefore, we have got conclusions below: 1. The rate of smokers who attended in 2005 KDTA was 33.93%, 46.3% in men, 1.44% in women. When we compared to other specialist groups, the rate of dental technician smokers was higher than them. 2. When we analyzed the ages of first smoking, 55.56% of the people started to smoke when they were in 24 years old. This result was very similar to the rate of dentist smokers in 2005 KDA research. 3. According to the answers of smokers and people who wire smokers in the past about quitting smoking period and willness in future, 60.82% among all members failed to quit smoking and also 69.2% among all members did not leap over 3 months but, they have thought to quit smoking for 6 months. 4. According to the answers about antismoking training related to environment in dental and clinical labs, most dental technicians(92.66%) have never been trained, also 37.70% among all members have not fulfilled their duty at self office. They have not recognized the danger of the indirect smoking. 5. When we asked chiefs in dental and clinical labs, the reason why they, didn't do the antismoking training their staffs, 32.1% of them replied that they were so busy, and 42.13% did because of their staffs, abhorrence and needlessness. 6. As Pan-dentistry members, over 80% agreed to the thought of the antismoking, also had medical knowledge about smoking. So we have the conclusion that dental technicians have identification as the Pan-dentistry members. 7. Most dental technicians expected KDTA to play a role about the antismoking training for their members. We have two suggestions to KDTA about the antismoking problem for members according to above conclusions. First, KDTA should prepare the antismoking training in the curriculum. Second, KDTA should support the antismoking programs of schools for students.

• Journal of Preventive Medicine and Public Health
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• v.14 no.1
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• pp.111-116
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• 1981

Economic development of Korea brought rapid progress and expansion of her industries. Accordingly, number of workers who have been exposed to hazardous metals are increasing. For better understanding the significance of on the job human metal pollution, a total of 22 solderers among autoworkers and 28 controls among medical students was purposively selected as samples of the study. From their blood, concentrations of cadmium and lead were measured with atomic absorption spectrophotometer, and to compare with statistical indices of controls those of solderers were sumarized as follows. 1. Each frequency distribution of cadmium and lead concentration in blood of solderers was more positively skewed showing non-Gausian distribution. 2. Interindividual variation of lead concentration in blood of solderers was markedly revealed. 3. Each mean of cadmium and lead concentration in blood of solderers was higher than that of controls(Cd;p<0.01, Pb;p<0.01). 4. Relative ratio of cadmium concentration in blood of solderers to that of controls was 1.36 by arithmatic mean and 1.39 by geometric mean. Relative ratio of lead concentration in blood of solderers to that of controls was 1.53 by arithmatic mean and 1.30 by geometric mean. 5. It was shown that concentration of lead is slightly correlated with that of cadmium both in solderers and controls(solderers; p<0.1, controls;p<0.1).

• Sleep Medicine and Psychophysiology
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• v.5 no.1
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• pp.111-117
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• 1998

Objectives : 'First-night effect' has been a well-known concept since 1960's. It is important because it is one of the major factors to be considered in assessing the reliability of polysomnographic data. However, 'reverse first-night effect' has also been described, resulting in the inconsistency of conceptualization. We attempted to investigate on the first-night effect in adults by having each of them take two nights of polysomnography in a controlled environment. Young healthy adult volunteers were chosen as subjects in order to rule out age- or health-related confounders. Methods : Polysomnography was performed on eight male medical students (mean $age=23.5\;{\pm}\;0.9$) for two nights with Grass model 78 polysomnograph. We scored manually under the standard protocol each epoch of the sleep records. Sleep variables were obtained and compared between the two nights. Results : Sleep period time(SPT) and total sleep time(TST) of the third fraction of night were significantly longer on the first night than on the second night (p<0.05). However, other sleep variables such as percentage of each sleep stage, sleep latency, REM sleep latency, number of waking, and sleep efficiency were not different between the two nights. Conclusion : We could not confirm the existence of first-night effect in this study. In healthy young male adults, it may not happen at all or may happen to a very negligible degree. Young healthy adults may have more adaptability to a new sleep environment. Also, the provision of a reasonably comfortable sleep environment could have helped them with abolition of first-night effect.

• Journal of Biomedical Engineering Research
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• v.24 no.4
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• pp.267-273
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• 2003

The present study attempted to observe what changes the supply of highly concentrated (30%) oxygen cause to people's ability of visuospatial cognition, compared to air of normal oxygen concentration (21%). This study sampled eight male university students (the average age : 23.5) as subjects for functional Magnetic Resonance Imaging (MRI) study It also developed equipment that supplies 21% and 30% oxygen) at a constant rate of 8L/min. Two questionnaires containing 20 questions were developed to measure the ability of visuospatial cognition, and accuracy was calculated from the result of task performance. The experiment paradigm consisted of the run conducting tasks at 30%'s concentration of oxygen and another run at 21%'s concentration of oxygen. Each run was composed of four blocks and each block included eight control tasks and five visuospatial taks. 3T MRI was used and fMRI was obtained through the single-shot EPI method. The activation in the occipital-associated area, bilateral superior parietal lobes, bilateral inferior parietal lobes. bilateral precuneus, bilateral postcentral gyri, bilateral middle frontal gyri, bilateral inferior frontal gyri, bilateral medial frontal gyri, bilateral superior frontal gyri, bilateral cingulate gyri was significantly increased at the 30%'s concentration of oxygen rather than 21%'s. Furthermore, the result of task performance showed the accuracy increased at 30%'s concentration of oxygen rather than 21%'s. From the result of this study, it is concluded that the supply of highly concentrated oxygen has a positive effect on the ability of visuospatial cognition.