• Bulletin of the Korean Chemical Society
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• v.31 no.11
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• pp.3421-3422
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• 2010

• Journal of Marine Life Science
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• v.7 no.2
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• pp.121-128
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• 2022

L-asparaginase (ASNase) is a therapeutic enzyme used to treat acute lymphoblastic leukemia. Currently, the most widely used ASNases are originated from bacteria. However, owing to the adverse effects of bacterial ASNases, new resources for ASNase production should be explored. Fungal enzymes are considered efficient and compatible resources of natural products for diverse applications. In particular, fungal species belonging to the genus Trichoderma are well-known producers of several commercial enzymes including cellulase, chitinase, and xylanase. However, enzyme production by marine-derived Trichoderma spp. remains to be elucidated. While screening for extracellular ASNase-producing fungi from marine environments, we found four strains showing extracellular ASNase activity. Based on the morphological and phylogenetic analyses using sequences of translation elongation factor 1-alpha (tef1α), the Trichoderma isolates were identified as T. afroharzianum, T. asperellem, T. citrinoviride, and Trichoderma sp. 1. All four strains showed different ASNase activities depending on the carbon sources. T. asperellem MABIK FU00000795 showed the highest ASNase value with lactose as a carbon source. Based on our findings, we propose that marine-derived Trichoderma spp. are potential candidates for novel ASNase production.

• Ocean and Polar Research
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• v.41 no.4
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• pp.289-309
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• 2019

Marine microalgae have long been used as food additives and feeds for juvenile fish and invertebrates as their nutritional content is beneficial for humans and marine aquaculture species. Recently, they have also been recognized as a promising source for cosmeceutical, nutraceutical, and pharmaceutical products as well as biofuels. Marine microalgae of various species are rich in multiple anti-oxidant phytochemicals and their bioactive components have been employed in cosmetics and dietary supplements. Oil contents in certain groups of marine microalgae are extraordinarily rich and abundant and therefore have been commercialized as omega-3 and omega-6 fatty acid supplements and mass production of microalgae-based biodiesels has been demonstrated by diverse research groups. Numerous natural products from marine microalgae with significant biological activities are reported yearly and this is attributed to their unique adaptive abilities to the great diversity of marine habitats and harsh conditions of marine environments. Previously unknown toxin compounds from red tide-forming dinoflagellates have also been identified which opens up potential applications in the blue biotechnology sector. This review paper provides a brief overview of the biotechnological potentials of Korean marine microalgae. We hope that this review will provide guidance for future marine biotechnology R&D strategies and the various marine microalgae-based industries in Korea.

• Proceedings of the Microbiological Society of Korea Conference
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• 2009.05a
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• pp.92-93
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• 2009

• Journal of Marine Bioscience and Biotechnology
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• v.15 no.2
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• pp.59-66
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• 2023

Dictyopteris divaricata, a type of marine brown algae, has been studied for its various biological properties, including anti-inflammatory, antidiabetic, and whitening effects. However, its potential antiobesity effects have not been extensively explored. This study aimed to examine the impact of D. divaricata ethanol extract (DDE) on adipocyte differentiation and adipogenesis using 3T3-L1 preadipocytes. Our results showed that when 3T3-L1 preadipocytes were treated with noncytotoxic concentrations of DDE there was a concentration-dependent decrease in fat accumulation rate and triglycerid production compared with the control. Furthermore, DDE significantly reduced the expression of transcription factors (PPARγ, C/EBPα, and SREBP-1) and fatty acid transport protein (FABP4), which are crucial for 3T3-L1 preadipocyte differentiation. These findings suggest that DDE may exhibit antiobesity effects by suppressing the expression of lipogenic transcription factors and fatty acid transport proteins. Therefore, DDE holds potential as a therapeutic agent for obesity.

• Journal of Marine Life Science
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• v.8 no.2
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• pp.136-149
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• 2023

Basic bioactivities (antioxidant, anti-inflammatory, antibacterial, anticancer, antiviral) were investigated from 370 strains of marine bacteria, fungi, and microalgae obtained from various marine environmental regions in Korea, and the activity results were obtained at the collection site, isolation source, and species level was compared. In the case of marine bacteria, strains belonging to the generally useful genera Streptomyces and Bacillus were observed to have particularly strong efficacy and useful resources were mainly isolated from marine sediments. In the case of marine fungi and microalgae, results showing strong species-specific activity were confirmed, and results showing efficacy-specific activity were also obtained. Based on these results, it is a research result that can facilitate priority access as a strategic material for industrial revitalization and the establishment of a strategy to secure resources based on usefulness when conducting research on chemicals that are selectively effective against specific diseases or when conducting resource-based research. In addition, we believe that by using these results as material for sale through the Marine BioBank (MBB), academia and industry can use them to help accelerate the revitalization of the marine bio industry.

• Proceedings of the Microbiological Society of Korea Conference
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• 2007.05a
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• pp.89-91
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• 2007

• Journal of Aquaculture
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• v.16 no.1
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• pp.59-65
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• 2003

General aspect of marine ranching programme in Korea was introduced. It contains the status of Korean fisheries industry, background and the scope of ranching project being conducted by KORDI since 1996. Long term plan for the marine ranching programme as a national project is also introduced including socio-economic analysis of project as well as economic impact of investment.

• Bulletin of the Korean Chemical Society
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• v.34 no.2
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• pp.357-358
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• 2013

• The Journal of Fisheries Business Administration
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• v.27 no.2
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• pp.27-49
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• 1996

The purpose of this paper is to find out how catches of certain species of marine fish in China influence the marine fisheries of Korea. The results are as follows: 1) While the catches of the main species of marine fish are over 74% in Korea, those of China are under 45%. 2) The main species of marine fish in China(MFC) are hair tails, jack mackerels, anchovies, mackerels, Spanish mackerels, pomfrets, redlip croakers, fie fish, sea breams, sardines, croakers and bigeyed herrings. 3) All the MFC belong to the main species of marine fish in Korea. 4) The fishing grounds of hair tails, jack mackerels, mackerels, Spanish mackerels, pomfrets and croakers in China are similar to those of Korea. 5) Catches of hair tails, jack mackerels, Spanish mackerels, pomfrets, file fish, sea breams and bigeyed herrings in China are many times more than those in Korea. Therefore Korea can't compete with China with such species of marine fish. 6) The price of MFC apart from mackerels and sardines is more competitive than the price of such species in Korea. When the catches of China's marine fish are imported, the species of China's marine fish that will have a great influence on the marine fisheries of Korea are hair tails, jack mackerels, pomfrets and sea breams.