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Acetycholinesterase Inhibiting Effect and Free Radical Scavenging Effect of Soybean(Glycine max) and Yak-Kong(Rhynchosia nolubilis) (대두와 약콩의 Acetylcholinesterase 활성 억제효과와 항산화 효과)

  • 강순아;한진아
    • Journal of the East Asian Society of Dietary Life
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    • v.14 no.1
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    • pp.64-69
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    • 2004
  • The deficiency of the neurotransmitter acetylcholine(ACh) is responsible for the initiation of Alzheimer's disease. In addition, there is a simple evidence that oxidative stress significantly increases in persons with Parkinson's disease compared to age-matched healthy persons. Therefore, the objective of the study was to investigate the neurodegeneration inhibitory effect of soybean(Glycine Max) and Yak-Kong(Rhynchosia Nolubilis) by measuring the degree of inhibiting Acetylcholinesterase (AChE) catabolizing the ACh and the free radical scavenger effect in vitro. AChE was measured by the minor modified Ellman assay. Free radical scavenging activity was measured using l-diphenyl-2-picrylhydrazyl (DPPH). First, the MeOH extracts of Soybean and Yak-Kong showed the AChE inhibiting activity of 62.0$\pm$2.43% and 65.0$\pm$3.29% at the 5 mg/$m\ell$ concentration. The 50% inhibitory concentration ($IC_{50}$/) of AChE was 1.96 and 1.31 mg/$m\ell$ in the MeOH extracts of soybean and Yak-Kong. Second, the MeOH extracts of soybean and Yak-Kong showed the free radical scavenger activity of 23.1$\pm$4.26% and 80.7$\pm$4.61% at the 5 mg/$m\ell$. IC50 of free radical scavenger activity in Soybean and Yak-Kong was 13.00 and 1.41 mg/$m\ell$ in MeOH extracts and was 5.95 and 2.74 mg/$m\ell$ in hot-water extracts, respectively. In this study, the extracts of Soybean and Yak-Kong showed powerful effects in the AChE inhibition and free radical scavenging. The extracts of Soybean and Yak-Kong were expected to prevent the many neurodegenerative diseases.

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Quantity Surveyors' Perception of Cost Impact Factors in Hong Kong Civil Engineering Projects

  • Chiu, Wai Yee Betty;Lau, Hat Lan Ellen
    • Journal of Construction Engineering and Project Management
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    • v.5 no.3
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    • pp.1-9
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    • 2015
  • Project cost is an important concern in any construction project. Although there has been a lot of studies on factors affecting the cost of construction projects, there seems no consensus as what cost factors have direct influence on the cost of civil engineering projects. This study therefore aims to bridge the current knowledge gap by examining quantity surveyors' perception of the factor structure among nineteen costing attributes identified based on literature review. Questionnaire was used to elicit responses from quantity surveyors working in the Hong Kong construction industry. Principal component analysis is conducted to extract the factor structure of the cost attributes and the attributes are grouped into three factor components, namely the contract management factor, the project management factor and the monetary value factor. Understanding these cost impact factors could be crucial in managing civil engineering projects, since it allows the project stakeholders and quantity surveyors to take precautionary steps to identify the cost management problems and areas for improvement and could even help to avoid cost deviations in engineering projects.

Prestressed concrete bridges with corrugated steel webs: Nonlinear analysis and experimental investigation

  • Chen, Xia-chun;Bai, Zhi-zhou;Zeng, Yu;Jiang, Rui-juan;Au, Francis T.K.
    • Steel and Composite Structures
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    • v.21 no.5
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    • pp.1045-1067
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    • 2016
  • Concrete bridges with corrugated steel webs and prestressed by both internal and external tendons have emerged as one of the promising bridge forms. In view of the different behaviour of components and the large shear deformation of webs with negligible flexural stiffness, the assumption that plane sections remain plane may no longer be valid, and therefore the classical Euler-Bernoulli and Timoshenko beam models may not be applicable. In the design of this type of bridges, both the ultimate load and ductility should be examined, which requires the estimation of full-range behaviour. An analytical sandwich beam model and its corresponding beam finite element model for geometric and material nonlinear analysis are developed for this type of bridges considering the diaphragm effects. Different rotations are assigned to the flanges and corrugated steel webs to describe the displacements. The model accounts for the interaction between the axial and flexural deformations of the beam, and uses the actual stress-strain curves of materials considering their stress path-dependence. With a nonlinear kinematical theory, complete description of the nonlinear interaction between the external tendons and the beam is obtained. The numerical model proposed is verified by experiments.

Implementation of The Personal Secretary System using Raspberry-Pi (라즈베리파이를 이용한 개인 비서 시스템 구현)

  • Park, Na-Hyun;Park, Ji-Hyun;Yun, So-Hyun;Park, Jeong-Sik;Kim, Tai-Woo
    • Journal of Internet of Things and Convergence
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    • v.3 no.1
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    • pp.1-8
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    • 2017
  • Information and time are very important for a modem life, and researches about the personal secretary system that provides specific information for each individual are being studied. In this research, we developed the personal secretary system called Genie which provides the user with desired informations such as weather, news, and traffic information with time. It is expected that the Genie system will provide information on news, weather, traffic information including bus arrival times, and memos with time so that users can find their own leisure time and live a comfortable life.

A study on the size of product shear surface in shearing process (전단 가공에서 제품 전단면의 크기에 변화에 관한 연구)

  • Son, Jong-Min;Lee, Hui-Ju;Cho, Gi-Heum;Shin, Seong-Eun;Kim, Sei-Whan;Lee, Chun-Kyu
    • Design & Manufacturing
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    • v.11 no.1
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    • pp.26-29
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    • 2017
  • Burrs generated during shear forming such as notching and piercing may cause lifting during product assembly, which may deteriorate the productivity and quality of products. In this study, various shear angles and variable clearances between the punch and the die were applied in experimental notching tests to investigate the shear fracture surface and the burr height due to various conditions. The experimental results show that the clearance has the greatest effect on shear and fracture surfaces. It is considered that the height of the shear section increases slightly as the shear angle increases.

Kinetics of di-n-Butyl Phthalate Degradation by a Bacterium Isolated from Mangrove Sediment

  • XU XIANG-RONG;GU JI-DONG;LI HUA-BIN;LI XIAO-YAN
    • Journal of Microbiology and Biotechnology
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    • v.15 no.5
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    • pp.946-951
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    • 2005
  • Biodegradation of the endocrine-disrupting chemical di-n-butyl phthalate (DBP) was investigated using a bacterium, Pseudomonas fluorescens B-1, isolated from mangrove sediment. The effects of temperature, pH, salinity, and oxygen availability on DBP degradation were studied. Degradation of DBP was monitored by solid-phase extraction using reversed-phase HPLC and UV detection. The major metabolites of DBP degradation were identified as mono-n-butyl phthalate and phthalic acid by gas chromatography-mass spectrometry (GC-MS) and a pathway of degradation was proposed. Degradation by P. fluorescens B-1 conformed to first-order kinetics. Degradation of DBP was also tested in seawater by inoculating P. fluorescens B-1, and complete degradation of an initial concentration of $100{\mu}g/l$ was achieved in 144 h. These results suggest that DBP is readily degraded by bacteria in natural environments.

Proposal a case study for an interactive game content of a genre convergence with Racing and Shooting (레이싱과 건슈팅 장르의 융복합 체감형 게임 사례 제안)

  • Li, Xuanxin;Ryu, Seuc-Ho;Kyung, Byung-Pyo;Lee, Dong-Yeol;Lee, Wan-Bok
    • Journal of the Korea Convergence Society
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    • v.2 no.1
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    • pp.51-56
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    • 2011
  • As fusion and composition of a game genre is actively achieved, game types where various genres coexist in a game increase. These games have advantage providing various funnies to game players. This study examines and analyzes game examples of fusion and composition genre that appear in the game market in accordance with such a trend. We suggested a game that can give new joy to players by application of fusion and composition of genre within the body type that can provide directly virtual experience of the given game situation on the base of this study.

Improving performance of deep-blue OLED by inserting ultra-thin LiF between hole-blocking and electron-transporting layers

  • Sun, J.X.;Zhu, X.L.;Yu, X.M.;Wong, M.;Kwok, H.S.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2006.08a
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    • pp.956-960
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    • 2006
  • Deep-blue organic light-emitting diodes (OLEDs) with/without ultra-thin LiF layer inserted at the interface between hole-blocking and electron-transporting layers have been fabricated and investigated. The fundamental structures of the OLEDs are ITO/m-MTDATA/NPB/BCP/LiF (with/ without)/ $Alq_3/LiF/Al.Deep$ blue light emission with CIE coordinate of (0.15, 0.11) has been achieved for all devices. Further, by inserting LiF with thickness of 1nm at the interface between BCP and $Alq_3$ layer, the luminous efficiency as well as the power efficiency is much improved compared to that without. The enhancement of electron injection due to insertion of LiF may account for this improvement.

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