• Clinics in Shoulder and Elbow
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• v.26 no.2
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• pp.162-168
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• 2023

Background: Reverse shoulder arthroplasty (RSA) has evolved continuously over recent years, with expanded indications and better outcomes. YouTube is one of the most popular sources globally for health-related information available to patients. Evaluating the reliability of YouTube videos concerning RSA is important to ensure proper patient education. Methods: YouTube was queried for the term "reverse shoulder replacement." The first 50 videos were evaluated using three different scores: Journal of the American Medical Association (JAMA) benchmark criteria, the global quality score (GQS), and the reverse shoulder arthroplasty-specific score (RSAS). Multivariate linear regression analyses were conducted to determine the presence of a relationship between video characteristics and quality scores. Results: The average number of views was 64,645.78±264,160.9 per video, and the average number of likes was 414 per video. Mean JAMA, GQS, and RSAS scores were 2.32±0.64, 2.31±0.82, and 5.53±2.43, respectively. Academic centers uploaded the highest number of videos, and surgical techniques/approach videos was the most common video content. Videos with lecture content predicted higher JAMA scores whereas videos uploaded by industry predicted lower RSAS scores. Conclusions: Despite its massive popularity, YouTube videos provide a low quality of information on RSA. Introducing a new editorial review process or developing a new platform for patients' medical education may be necessary. Level of evidence: Not applicable.

• The Korean Journal of Physiology and Pharmacology
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• v.28 no.1
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• pp.59-72
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• 2024

To investigate the mechanism of Wenshen Xuanbi Decoction (WSXB) in treating osteoarthritis (OA) via network pharmacology, bioinformatics analysis, and experimental verification. The active components and prediction targets of WSXB were obtained from the TCMSP database and Swiss Target Prediction website, respectively. OA-related genes were retrieved from GeneCards and OMIM databases. Protein-protein interaction and functional enrichment analyses were performed, resulting in the construction of the Herb-Component-Target network. In addition, differential genes of OA were obtained from the GEO database to verify the potential mechanism of WSXB in OA treatment. Subsequently, potential active components were subjected to molecular verification with the hub targets. Finally, we selected the most crucial hub targets and pathways for experimental verification in vitro. The active components in the study included quercetin, linolenic acid, methyl linoleate, isobergapten, and beta-sitosterol. AKT1, tumor necrosis factor (TNF), interleukin (IL)-6, GAPDH, and CTNNB1 were identified as the most crucial hub targets. Molecular docking revealed that the active components and hub targets exhibited strong binding energy. Experimental verification demonstrated that the mRNA and protein expression levels of IL-6, IL-17, and TNF in the WSXB group were lower than those in the KOA group (p < 0.05). WSXB exhibits a chondroprotective effect on OA and delays disease progression. The mechanism is potentially related to the suppression of IL-17 and TNF signaling pathways and the down-regulation of IL-6.

• Clinics in Shoulder and Elbow
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• v.26 no.3
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• pp.238-244
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• 2023

Background: Many patients use online resources to educate themselves on surgical procedures and make well-informed healthcare decisions. The aim of our study was to evaluate the quality and readability of online resources exploring shoulder arthroplasty. Methods: An internet search pertaining to shoulder arthroplasty (partial, anatomic, and reverse) was conducted using the three most popular online search engines. The top 25 results generated from each term in each search engine were included. Webpages were excluded if they were duplicates, advertised by search engines, subpages of other pages, required payments or subscription, or were irrelevant to our scope. Webpages were classified into different source categories. Quality of information was assessed by HONcode certification, Journal of the American Medical Association (JAMA) criteria, and DISCERN benchmark criteria. Webpage readability was assessed using the Flesch reading ease score (FRES). Results: Our final dataset included 125 web pages. Academic sources were the most common with 45 web pages (36.0%) followed by physician/private practice with 39 web pages (31.2%). The mean JAMA and DISCERN scores for all web pages were 1.96±1.31 and 51.4±10.7, respectively. The total mean FRES score was 44.0±11.0. Only nine web pages (7.2%) were HONcode certified. Websites specified for healthcare professionals had the highest JAMA and DISCERN scores with means of 2.92±0.90 and 57.96±8.91, respectively (P<0.001). HONcode-certified webpages had higher quality and readability scores than other web pages. Conclusions: Web-based patient resources for shoulder arthroplasty information did not show high-quality scores and easy readability. When presenting medical information, sources should maintain a balance between readability and quality and should seek HONcode certification as it helps establish the reliability and accessibility of the presented information. Level of evidence: IV.

• Clinics in Shoulder and Elbow
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• v.27 no.1
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• pp.39-44
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• 2024

Background: Displaced olecranon fractures constitute a challenging problem for elbow surgeons. The purpose of this study is to evaluate the role of suture anchor fixation for treating patients with displaced olecranon fractures. Methods: A retrospective review was performed for all consecutive patients with displaced olecranon fractures treated with suture anchor fixation with at least 2 years of clinical follow-up. Surgical repair was performed acutely in all cases with nonmetallic suture anchors in a double-row configuration utilizing suture augmentation via the triceps tendon. Osseous union and perioperative complications were uniformly assessed. Results: Suture anchor fixation was performed on 17 patients with displaced olecranon fractures. Functional outcome scores were collected from 12 patients (70.6%). The mean age at the time of surgery was 65.6 years, and the mean follow-up was 5.6 years. Sixteen of 17 patients (94%) achieved osseous union in an acceptable position. No hardware-related complications or fixation failure occurred. Mean postoperative shortened disabilities of the arm, shoulder, and hand (QuickDASH) score was 3.8±6.9, and mean Oxford Elbow Score was 47.5±1.0, with nine patients (75%) achieving a perfect score. Conclusions: Suture anchor fixation of displaced olecranon fractures resulted in excellent midterm functional outcomes. Additionally, this technique resulted in high rates of osseous union without any hardware-related complications or fixation failures.

• Journal of Environmental Science International
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• v.19 no.4
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• pp.447-457
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• 2010

This study aims to monitor the variation of concentration of PCDD/DFs between the gaseous phase-particulate phases in the ambient air of urban area in Korea. This monitoring is evaluated by using the Junge-Pankow model and the Koa absorption model with the application of the Octanol-air partition coefficient. In this study, the ambient air samples were analyzed according to each congener group of the PCDD/DFs by HRGC/HRMS, which have been investigated for the past 5 years. In the results, the annual variation in the concentration level of $\Sigma$PCDD/DFs in TSP was increased from $1588\;fg/m^3$ in 1998 to $5123\;fg/m^3$ in 2002, and from 31 fg I-TEQ/$m^3$ to 94 fg I-TEQ/$m^3$ in the $\Sigma$I-TEQ. In the case of PUF of gaseous phase sample, their variation was increased from $1615\;fg/m^3$ in 1998 to $2237\;fg/m^3$ in 2002, and in the $\Sigma$I-TEQ from 12 fg I-TEQ/$m^3$ to 17 fg I-TEQ/$m^3$. The relative coefficient between the gas phase concentration of PCDD/DFs and the temperature was a value of 0.744; the contributive rate of the temperature to the gaseous phase concentration was 0.554. According to the results, the pattern of the coefficient of distribution based on log $p_L^0$ is similar to the ambient air of the urban areas.

• Journal of Korea Water Resources Association
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• v.39 no.3 s.164
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• pp.241-252
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• 2006

Numerical models for seepage analysis are useful tools to analyze problems and design protection techniques that are related to seepage through a levee. Though every model may have its own limitations and shortcomings, there were no generalized verifications or calibrations for the commercial models. It means that users can run the model and get the result without understanding nor taking any enough training. This paper Investigates applicability and suitability of some seepage numerical models by comparing analytical solutions with experiments in the user's viewpoint. The results showed that it is more desirable to use analyses with unsaturated-unsteady condition rather than those with saturated-steady conditions, since seepage phenomenon of real levees are changed according to water level and soil property. This study also compared the calculated unsteady solutions with the calculated steady solutions for the levee at Koa of the Nakdong River The comparison revealed that as the result, the safety factor of $2.0{\sim}3.5$ has the same effects for seepage protection techniques when they are designed on the basis of steady-state analysis.