• Title/Summary/Keyword: Kinetic control

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Dynamic characteristics of a CSTR with MMA polymerization

  • Ahn, Jong-Pil;Rhee, Hyun-Ku
    • 제어로봇시스템학회:학술대회논문집
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    • 1992.10b
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    • pp.100-105
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    • 1992
  • A mathematical model is developed for a CSTR in which free radical solution polymerization of methyl methacrylate(MMA) takes place. It turns out that five ordinary differential equations are to be treated simultaneously in order to predict the reactor performance. Although the reaction proceeds under the conditions of relatively low temperature and pressure, the system shows very complex bifurcation features due to the diffusion limitation (gel effect) and the temperature dependence of the kinetic parameters and physical properties. The effects of various system parameters on the reactor performance as well as on the polymer properties are investigated by using the bifurcation analysis. The application of the singularity theory enables us to divide the parameter space into several different regions, in each of which the system takes a unique steady state structure. Under certain circumstances, complex dynamic features such as HB points and limit cycles are observed and these should be taken into consideration in the reactor design.

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Development of Micro Tool using High Speed Etching Process (고속 회전에칭을 이용한 미세공구의 개발)

  • 김성헌;박준민;정해도
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2000.05a
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    • pp.959-962
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    • 2000
  • In this study, the micro shaft was fabricated by high speed etching process. The integration of the kinetic energy of circumference and the effect of etching takes less time to fabricate the micro shaft than any other conventional methods. First, the end part of the rod(SKD11) was dipped in chemical solution(FeCl$_3$) and the rod rotated at high speed(3500-10000rpm). Experimental setup was simply composed of high speed motor. chemical solution and $\Phi$ 1 mm rod. The main factors of diameter control are chemical concentration, reaction time and rpm. has a result. the diameter of the dipped rod was decreased by 200${\mu}{\textrm}{m}$ by high speed rotation and its shape and surface was good. From this experiment, we found the possibility to manufacture micro shaft without very expensive equipment.

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A Study on the Treatment of Distillery Wastewater by Single-phase and Two-phase Anaerobic Digestion (단상(單相) 및 2상(相) 혐기성(嫌氣性) 소화(消化)에 의한 주정폐수(酒精廢水) 처리(處理)에 관한 연구(硏究))

  • Choung, Young Kyoo;Rah, Seung Woo;Park, Joon Hwan
    • Journal of Korean Society of Water and Wastewater
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    • v.7 no.1
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    • pp.5-12
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    • 1993
  • The objectives of this paper are to present data to illustrate how an advanced digestion process, two-phase digestion, can provide superior performance in terms of waste stabilization efficiency and net energy recovery. As the result, it is possible to separate enrichment cultures of acidogenic and methanogenic organisms in isolated environments by kinetic control involving manipulation of dilution rates. In single-phase digestion process, HRT and COD loading for effective operation were 14.29 days and 2.33kg $COD/m^3$ day, but two-phase digestion may be conducted efficiently at 7 days of HRT and 5.71kg $COD/m^3$ day of loading. Data from this studies showed that the two-phase process is better than single-phase digestion under all test conditions when compared on the bases of gas yield and production rate, reductions of COD and VS, buffer capacity, and unconverted volatile acids in the effluent.

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Effects of Femara and Tamoxifen on Proliferation of FM3A Cells in Culture

  • Topcul, Mehmet;Topcul, Funda;Cetin, Idil
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.2819-2822
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    • 2013
  • In this study, antiproliferative effects of the selective estrogen receptor modulator Tamoxifen and the aromatase inhibitor letrozole (Femara) were evaluated and compared using the FM3A cell line, originating from a C3H mouse mammary carcinoma and positive in terms of estrogen receptor (ER) expression. Cell kinetic parameters including labelling index, mitotic index and labelling index were assessed after exposure of the. FM3A cell line to $0.001{\mu}g/ml$ of Tamoxifen and $0.25{\mu}g/ml$ of Femara for 4, 8, 16 and 32 h for all parameters. The results showed that cell growth was inhibited by both agents. There was a significant decrease in labelling index and mitotic index and significant increase in apoptotic index for all experimental groups. The differences between control and all experimental groups were statistically significant (p<0.001) for all applications.

Simulation of the Mixed Layer in the Western Equatorial Pacific Warm Pool

  • Jang, Chan-Joo;Noh, Yign
    • Ocean and Polar Research
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    • v.24 no.2
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    • pp.135-146
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    • 2002
  • The upper ocean in the western equatorial Pacific warm pool during TOGA-COARE IMET IOP was simulated using a one-dimensional turbulence closure ocean mixed-layer model, which considered recent observations, such as the remarkable enhancement of turbulent kinetic energy near the ocean surface. The shoaling/deepening of the mixed layer and warming/cooling subsurface water in the model were in reasonable agreement with the observations. There was a significant improvement in simulating the cooling trend of the sea surface temperature under a westerly wind burst with heavy rainfall over previous simulations using bulk mixed-layer models. By contrast the simulated sea surface salinity (SSS) departed significantly from the observed SSS, especially during a westerly burst and the subsequent restratification period, which might be due to 3-D control processes, such as downwelling/upwelling or advection.

Fuzzy control of a Fed-Batch Fermentation with Substrate Inhibition Kinetics (기질저해가 있는 유가식 발효공정의 퍼지제어)

  • 최정우;오승목;이광순;이원홍
    • Journal of the Korean Institute of Intelligent Systems
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    • v.3 no.3
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    • pp.3-18
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    • 1993
  • 본 논문에서는 박테리아에서 생성되는 생체 계면활성제인 emulsan의 생산을 위한 유가식 배양에서 에칸을 농도의 제어에 퍼지기법을 적용하였다. 기절저해가 있는 유가식 배양에서 emulsan의 생산을 향상시키기 위해 최대 비성장속도를 갖는 최적 기질농도가 유지되도록 기질인 에탄올의 공급 속도가 조절되어 졌다. 생물반응기에서 Acunetobacter calcoaceticus RAG-1 박테리아를 회분식과 유가식으로 배양 실험하여 최적 에탄올 농도를 구하고, kinetic 모델을 제시하였다. 배양실험의 결과와 지식을 바탕으로 퍼지 규칙을 구성하였다. 퍼지 제어기에서 제어 입력변수는 기질농도의 최적치와 운전치의 오차와 오차의 변화로서 구성되고, 제어 출력변수는 기질 공급 속도의 변화량으로 구성되었다. 멤버쉽 함수를 입력변수의 퍼지 집합화 과정을 통하여 구하였고, 최소-최대법과 무게 중심법을 이용하여 출력 제어값을 구하였다. 유가식 배양의 전산모사와 실험 결과에서 퍼지제어 기법은 최적 기질 농도를 정확히 제어하였으며, emulsan 생산은 향상되었다.

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Highly Economic and High Quality Zinc-flake Manufacturing by High Kinetic Processing

  • Ren, H.;Benz, H.U.;Chimal V., O.;Corral G., M.S.;Zhang, Y.;Jaramillo V., D.;Zoz, H.
    • Proceedings of the Korean Powder Metallurgy Institute Conference
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    • 2006.09b
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    • pp.975-976
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    • 2006
  • The present paper is a parameter study of zinc flake production using a Simoloyer CM01 horizontal high energy rotary ball mill. The manufactured flakes have a dimension in thickness (t) < $1{\mu}m$ and diameters (d) 5-100 ${\mu}m$, consequently a ratio d/t up to 200. The flake geometry is mainly controlled by the variation of process parameters such as rotary speed of the rotor, ratio of powder/ball charge, load ratio of the system, process temperature, operating model and the quantity of process control agent (PCA). The Zn flakes were characterized by SEM, tap densitometry, laser diffraction and water coverage measurement.

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Kinetic analysis of the foot and ankle (발과 족관절의 운동학적 분석)

  • Kim, Jae-Hun
    • PNF and Movement
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    • v.6 no.3
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    • pp.29-35
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    • 2008
  • Purpose : To describes the important aspects of the foot and ankle movement and function used when git and balance strategy. Method : The foot and ankle was a very important roles in the lower limb movement and gait. This study summarizes the physiologic movement of knee to the PNF lower extremity patterns. Result : The ankle joint composed of the talocural joint, the subtalarl joint, transverse tarsal joint, talocalcaneonavicular joint. The onset of dorsiflexion muscle activity starts in pre swing gait patterns. First contract muscle is the extensor hallucis. Activity of tibialis anterior and extensor digitorum longus quickly follows in mid swing gait phase. During stance phase, the soleus and gastrocnemius muscle provided plantar flexor torque, which muscle reacts quickly to restrain ankle dorsiflexion, and contributes modulated control of the ankle motion in gait patterns. Conclusions : The understanding of ankle kinematics, could provide a good therapeutic approach for improving gait patterns in patients with various pathological condition.

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Reactivity Measurement of Reacto (원자로의 반응도 측정에 관하여)

  • 고병준
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.4 no.3
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    • pp.19-27
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    • 1967
  • In the reactor control system, it is one of important part to know the accurate reactivity variability in order to keep the safe operation of the reactor which has the high flux neutron density, a short neutron life time and a large sudden reactivity insertion. For this problem, the reactivity measurement study is described by the analog computing method using the characteristics of the reactor kinetic equation.

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Modelling of a Biomolecular Processing for the Production and Secretion of Monoclounal Antibody (단일콜론항체 생산 및 분비에 대한 생물분자공정의 모델링)

  • 박재성;박선호
    • KSBB Journal
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    • v.13 no.4
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    • pp.369-377
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    • 1998
  • To analyze the unique aspects of biomolecular processing for monoclonal antibody (MAb) production and secretion, the simple working model based on 3-compartment (endoplasmic reticulum, Golgi apparatus, and extracellular medium) was developed. Based on in vitro MAb assembly experimental results, the kinetic model for MAb assembly in the endoplasmic reticulumn was proposed. The dynamics of MAb assembly and secretion was simulated using methematica program. According to the simulation results, the proposed 3-compartment model provides an efficient means to predict the specific MAb productivity as well as intracompartmental concentrations of MAb in endoplasmic reticulum, Golgi apparatus, and extracellular compartment model. In vivo profiles of MAb intermediates gave good agreements with the simulation profiles predicted by the intracellular compartment model. Furthermore, results of such analysis can help in directing the control strategy for optimum biomolecular processing in a mammalian cell culture system.

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