• Maxillofacial Plastic and Reconstructive Surgery
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• v.34 no.1
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• pp.65-70
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• 2012

Polymorphous low-grade adenocarcinoma (PLGA) is a neoplasm that is regarded as the second most common malignant salivary gland tumor after mucoepidermoid carcinoma. After the diagnosis of PLGA it is important to make a treatment decision and consider the prognosis. A histopathologic examination is necessary for diagnosis. Treatment is primarily surgical excision and long-term follow up is essential to evaluate local recurrences. This report describes 2 cases of PLGA located in the soft palate without any evidence of metastasis. The first case was PLGA with bony infiltration and an irregular margin lesion. The second case was PLGA localized in palatal soft tissue. We present diagnoses, histopathologic features, treatments and prognosis of PLGA.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.34 no.6
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• pp.455-461
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• 2012

Ankylosing spondylitis (AS) is a chronic autoimmune disease mainly involving the axial skeleton. The pathology of the disease is usually found at the sacroiliac joint, and half of the patients experience cervical spine invasion, but eventually, the whole spine is affected. The involvement of the temporomandibular joint (TMJ) in AS has not been investigated very well. A review of the literature revealed that there are only a few studies of TMJ involvement in AS that combined clinical and radiographic examinations. These studies show widely different results, ranging between 4% and 32%. We experienced Bilateral osseous ankylosis of the jaw treated by total alloplastic joint replacement in AS, and offer a case report.

• Journal of Ginseng Research
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• v.32 no.2
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• pp.114-119
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• 2008

Terpene synthase plays a key role in biosynthesis of triterpene saponins (ginsenosides) and is intermediate in the biosynthesis of a number of secondary metabolites. A terpene synthase (PgTPS) cDNA was isolated and characterized from the root of Panax ginseng c.A. Meyer. The deduced amino acid sequence of PgTPS showed a similarity with A. deliciosa (AAX16121) 61%, V. vinifera (AAS66357) 61%, L. hirsutum (AAG41891) 55%, M. truncatula (AAV36464) 52%. And the segment of a terpene synthase gene was amplified by reverse transcriptase-polymerase chain reaction (RTPCR). We studied expression of terpene synthase under stressful conditions like chilling, salt, UV, and heavy metal stress treatment. Expression of PgTPS was increased gradually after exposure to stresses such as chilling, salt, and UV illumination. But its transcription seems to be reduced by cadmium and copper treatment.

• Proceedings of the Korean Fiber Society Conference
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• 2003.04a
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• pp.154-156
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• 2003

다양한 가전기기의 보급과 전파통신의 수요증대에 따라 전자파의 차폐성능은 기기들의 품질 평가의 중요한 요인으로 작용하고 있다. 더구나 휴대용 전자장비의 경량/소형화되는 추세에 따라 인체의 착용에 따른 전자파의 유해성에 대한 논란이 커지고 있다. 지금까지 전자파 문제를 해결하기 위해 차폐성이 있는 재료로써 case를 만들거나, box 구조물에 전자파 발생기기를 넣고, 이를 차폐재로 코팅하여 사용하고 있다. (중략)

• Journal of Korean Medicine Rehabilitation
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• v.20 no.4
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• pp.63-72
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• 2010

Objectives : The purpose of this literature is to establish theoretical bases of using thermotherapy of cutaneous and muscle meridian(hot poultice). Methods : We reviewed literatures and books about thermotherapy in Traditional Korean medicine. Results and conclusions : Thermotherapy of cutaneous and muscle meridian(hot poultice) has developed from Yu-fa(熨法), a kind of poultice(also called cataplasm). Using it practically in the clinic, we simultaneously analyzed the distributions of cutaneous meridian(經法) and muscle meridian(經筋) and observed the symptoms of a disease to select treatment region. It has characteristic and originality differentiated form western physical therapy because it makes the function of whole body as well as an affected part better.

• BMB Reports
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• v.41 no.4
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• pp.338-343
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• 2008

Dehydrins (DHNs) compose a family of intrinsically unstructured proteins that have high water solubility and accumulate during late seed development at low temperature or in water-deficit conditions. They are believed to play a protective role in freezing and drought-tolerance in plants. A full-length cDNA encoding DHN (designated as ClDhn) was isolated from an oriental medicinal plant Codonopsis lanceolata, which has been used widely in Asia for its anticancer and anti-inflammatory properties. The full-length cDNA of ClDhn was 813 bp and contained a 477 bp open reading frame (ORF) encoding a polypeptide of 159 amino acids. Deduced ClDhn protein had high similarities with other plant DHNs. RT-PCR analysis showed that different abiotic stresses such as salt, wounding, chilling and light, triggered a significant induction of ClDhn at different time points within 4-48 hrs post-treatment. This study revealed that ClDhn assisted C. lanceolata in becoming resistant to dehydration.

• Journal of Ginseng Research
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• v.36 no.4
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• pp.442-448
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• 2012

Somatic embryogenesis is one of good examples of the basic research for plant embryo development as well as an important technique for plant biotechnology such as medicinally important plants. Single embryos develop into normal plantlets with shoots and roots. Therefore, direct single embryogenesis derived from single cells is highly important for normal plant regeneration. Here we demonstrate that the cyclic secondary somatic embryogenesis in Panax ginseng Meyer is a permanent source of embryogenic material that can be used for genetic manipulations. Secondary somatic embryos were originated directly from the primary somatic embryos on hormone-free Murashige and Skoog medium, and proliferated further in a cyclic manner. EM medium (one third of modified MS medium [MS medium containing half amount of NH4NO3 and KNO3] with 2% to 3% sucrose) favored further development of proliferated secondary somatic embryos into plantlets with root system. The plantlets developed into plants with well-developed taproots in half-strength Schenk and Hildebrandt basal medium supplemented with 0.5% activated charcoal.

• The Journal of Internal Korean Medicine
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• v.39 no.4
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• pp.822-830
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• 2018

Objective: This case report describes the treatment of hemoptysis in a bronchiectasis patient with Hyunggaeyungyo-tang plus Gamijihwang-tang. Methods: The hemoptysis in this patient was suspected to result from bronchiectasis, which was diagnosed with a chest CT at another hospital. She was treated with a herbal medicine, Hyunggaeyungyo-tang, plus Gamijihwang-tang. The effectiveness of the treatment was evaluated by measuring the amount of hemoptysis and by a visual analogue scale (VAS) to determine the patient's quality of life. Results: After administration of Hyunggaeyungyo-tang plus Gamijihwang-tang, the severity of hemoptysis decreased, based on the amount of hemoptysis and the VAS scores. Conclusions: Hyunggaeyungyo-tang plus Gamijihwang-tang is a potent therapeutic agent for the treatment of hemoptysis.

• Journal of Ginseng Research
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• v.35 no.3
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• pp.301-307
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• 2011

To evaluate the difference in expressing pharmacological effects of ginseng by intestinal microflora between Koreans, metabolic activities of ginseng, ginsenoside $Rb_1$ and $Rg_1$ by 100 fecal specimens were measured. The ${\beta}$-glucosidase activity for p-nitrophenyl-${\beta}$-D-glucopyranoside was 0 to 0.42 mmol/min/mg and its average activity (mean${\pm}$SD) was $0.10{\pm}0.07$ mmol/min/mg. The metabolic activities of ginsenosides Rb1 and Rg1 were 0.01 to 0.42 and 0.01 to 0.38 pmol/min/mg, respectively. Their average activities were $0.25{\pm}0.08$ and $0.15{\pm}0.09$ pmol/min/mg, respectively. The compound K-forming activities from ginsenoside Rb1 and ginseng extract were 0 to 0.11 and 0 to 0.02 pmol/min/mg, respectively. Their average compound K-forming activities were $0.24{\pm}0.09$ pmol/min/ mg and $2.14{\pm}3.66$ fmol/min/mg, respectively. These activities all were not different between males and females, or between ages. Although compound K-forming activity from the aqueous extract of ginseng was low compared to that from ginenoside $Rb_1$, their profiles were similar to those of isolated compounds. Based on these findings, we believe that the intestinal bacterial metabolic activities of ginseng components are variable in individuals and may be used as selection markers for responders to ginseng.

• Advances in Traditional Medicine
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• v.7 no.5
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• pp.540-548
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• 2008

Paeonia radix is the root of Paeonia aliflora Pallas, which is a perennial plant classified in the family Paeoniaceae. Paeonia radix possesses several pharmacological effects such as analgesic, anti-inflammatory and anti-allergic, anti-oxidative, and anti-coagulant activities. In this study, we investigated the effect of the aqueous extract of Paeonia radix on the lipopolysaccharide-induced inflammation in mouse BV2 microglial cells. The aqueous extract of Paeonia radix at respective concentration was treated one hour before lipopolysaccharide treatment. In the present results, the aqueous extract of Paeonia radix suppressed prostaglandin $E_2$ synthesis and nitric oxide production by inhibiting the lipopolysaccharide-stimulated mRNA expressions of cyclooxygenase-2 and inducible nitric oxide synthase in mouse BV2 microglial cells. These results demonstrate that Paeonia radix exerts anti-inflammatory and analgesic effects probably by suppressing mRNA expressions of cyclooxygenase-2 and inducible nitric oxide synthesis. The present study demonstrates that Paeonia radix may offer a valuable mean of therapy for brain inflammatory diseases.