• Microbiology and Biotechnology Letters
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• v.44 no.3
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• pp.229-235
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• 2016

Korea has a long history of brewing traditional rice wine using a authentic starter culture called nuruk, which contains natural microbial flora. Because rice wine is consumed fresh without filtration, its viable cells contribute to the biological activities of the wine. In numerous studies, microbial strains isolated from rice wine have been screened for their functionalities, which were mainly probiotic properties and antimicrobial activities. Indeed, some lactic acid bacteria (LAB) were confirmed to have strong probiotic activities as well as other health-promoting effects. Moreover, some of the isolated probiotic strains produced functional compounds, such as exopolysaccharides and γ-aminobutyric acid. For antimicrobial activities, some LAB and yeast strains were identified to produce bacteriocins and killer toxins, respectively, with significantly broad spectrum of antimicrobial activity. These functional strains originating from traditional rice wine and their metabolites can be used directly for the production of value-added food products.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7335-7338
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• 2013

There is increasing evidence that natural killer (NK) cells play an important role in antitumor immunity following dendritic cell (DC) vaccination. Little is known, however, about the optimal stimulation of DCs by epitopes and NK interactions for cytotoxicity in tumors. In this study, DC cells activated by the HPV16E7.49-57 epitope and LPS were co-cultured with NK cells in vitro, and then used ot immunize mice to study CTL activity of TC-1, which constitutively expresses HPV16E6E7, with an LDH release assay. Cytotoxicity in mice immunized with DC loaded with epitope HPVE7.49-57 vaccine co-cultured with NK was enhanced significantly (p<0.01). In conclusion, talk-across between DC and NK cells enhances their functions, also improving cytotoxicity againsttumor cells, suggesting that activated DC-NK by epitopes has potential application for cancer-specific immuno-cellular therapy.

• ICROS
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• v.15 no.3
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• pp.40-46
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• 2009

1997년 개념적 형태의 제안 이후 LBS는 위치 기술의 고도화, 인터넷 및 이동통신 기술의 발전 등을 통해 기술적 발전을 거듭해 왔으며 3세대 이후 이동통신 분야에서의 Digital Convergence 흐름을 고려할 때, 향후 Killer Application으로 성장할 것으로 예상된다. 이러한 시점에서 본 논문에서는 위치기반서비스(LBS:Location based service)기술의 흐름을 이해하고 미래의 LBS 기술 발전 방향을 파악하고자 LBS의 표준의 과거와 현재, 그리고 미래를 살펴보고자 한다. 구체적으로 LBS 관련하여 진행 중인 3GPP, 3GPP2, IEEE 등의 기술 표준 단체 및 OMA, OGC, WiMAX Forum등의 서비스 표준 단체에 대한 소개와 표준화 동향에 대하여 분석한다.

• Proceedings of the Korean Information Science Society Conference
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• 2003.10c
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• pp.382-384
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• 2003

인터넷 멀티캐스트 서비스는 네트워크 자원의 효율적 사용이라는 장점과 15년 이상의 연구, 개발에도 불구하고 아직 보편화 되지 못하고 있다. 이는 멀티캐스트 서비스가 망에서 지원이 잘 되지 않고 있고. 멀티캐스트 망 관리의 어려움. Killer Application 부재 등 많은 문제점이 있고, 멀티캐스트 서비스의 신뢰성 보장이 되지 않고 있다는 것도 하나의 문제점 이라고 할 수 있다. 본 논문에서는 인터넷 멀티캐스트 서비스의 신뢰성 보장을 위한 방법으로 기존에 발표된 트리기반의 프로토콜인 RMTP (Reliable Multicast Transport Protocol)[1]. [2]의 단점을 보완하여 신뢰성 있는 멀티캐스트 전송을 위한 방법을 제안하고자 한다.

• Journal of Information Processing Systems
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• v.1 no.1 s.1
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• pp.86-95
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• 2005

Location-based services or LBS refer to value-added service by processing information utilizing mobile user location. With the rapidly increasing wireless Internet subscribers and world LBS market, the various location based applications are introduced such as buddy finder, proximity and security services. As the killer application of the wireless Internet, the LBS have reconsidered technology about location determination technology, LBS middleware server for various application, and diverse contents processing technology. However, there are fears that this new wealth of personal location information will lead to new security risks, to the invasion of the privacy of people and organizations. This paper describes a novel security approach on open LBS service to validate certificate based on current LBS platform environment using XKMS (XML Key Management Specification) and SAML (Security Assertion Markup Language), XACML (extensible Access Control Markup Language) in XML security mechanism.

• Proceedings of the KSRS Conference
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• 2002.10a
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• pp.854-859
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• 2002

Location Based Services, or LBS refers to value-added service by processing information utilizing mobile user location. With the rapidly increasing wireless internet subscribers and world LBS market, the various location based applications are introduced such as buddy finder, proximity and security services. As the killer application of the wireless internet, the LBS has preconsidered technology about location determination technology, LBS middleware server for various application, and diverse contents processing technology. This paper describes the open architecture for LBS platform ensuring interoperability among the wireless networks and various location-based application services and the functional requirements for the LBS platform. The LBS platform in a narrow sense provides a standard interfaces for location management and network management for location services as follows, positioning (location acquisition through network or/and handset), location managing, location based functions, profile management, authentication and security, location based billing, information roaming between carriers and the system monitoring independent to specific network or ISP/CPs(Content Providers).

• Molecules and Cells
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• v.25 no.2
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• pp.178-183
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• 2008

To investigate the effects of electro-acupuncture (EA) treatment on regions remote from the application, we measured cellular, enzymatic, and transcriptional activities in various internal tissues of healthy rats. The EA was applied to the well-identified acupoint ST36 of the leg. After application, we measured the activity of natural killer cells in the spleen, gene expression in the hypothalamus, and the activities of antioxidative enzymes in the hypothalamus, liver and red blood cells. The EA treatment increased natural killer cell activity in the spleen by approximately 44%. It also induced genes related to pain, including 5-Hydroxytryptamine (serotonin) receptor 3a (Htr3a) and Endothelin receptor type B (Ednrb) in the hypothalamus, and increased the activity of superoxide dismutase in the hypothalamus, liver, and red blood cells. These findings indicate that EA mediates its effects through changes in cellular activity, gene expression, and enzymatic activity in multiple remote tissues. The sum of these alterations may explain the beneficial effects of EA.

• Proceedings of the IEEK Conference
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• 2005.11a
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• pp.11-14
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• 2005

In this paper, we propose a method for transmitting SMS(Short Message Service) for VoIP(Voice over IP) service supporting multi-protocol. The multi-protocol VoIP under consideration are generally composed of H.323, SIP and MGCP and Most ITSPs(Internet Telephony Service Provider) provide VoIP service with H.323 and SIP now. SMS is killer application in mobile telecom service and many people of various field use that service. For example, user can send many SMS messages and substitute e-mail. Also SMS can be provided with various internet application. Ahn, legacy phone of KT, can use SMS. Therefore VoIP phone also can be required with the same requirement. With the multi-protocol VoIP we will propose several methods sending efficiently SMS. To show the validity of the proposed method some examples are given in which the results can be expected by intuitive observation.

• Molecules and Cells
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• v.44 no.5
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• pp.328-334
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• 2021

The advent of the major histocompatibility complex (MHC) multimer technology has led to a breakthrough in the quantification and analysis of antigen-specific T cells. In particular, this technology has dramatically advanced the measurement and analysis of CD8 T cells and is being applied more widely. In addition, the scope of application of MHC multimer technology is gradually expanding to other T cells such as CD4 T cells, natural killer T cells, and mucosal-associated invariant T cells. MHC multimer technology acts by complementing the T-cell receptor-MHC/peptide complex affinity, which is relatively low compared to antigen-antibody affinity, through a multivalent interaction. The application of MHC multimer technology has expanded to include various functions such as quantification and analysis of antigen-specific T cells, cell sorting, depletion, stimulation to replace antigen-presenting cells, and single-cell classification through DNA barcodes. This review aims to provide the latest knowledge of MHC multimer technology, which is constantly evolving, broaden understanding of this technology, and promote its widespread use.

• Journal of Broadcast Engineering
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• v.13 no.6
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• pp.817-827
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• 2008

The terrestrial-digital multimedia broadcasting(T-DMB) is now provided for the public service and the number of receivers reaches 15 million at the present of August 2008. The service of T-DMB itself has been succeeded in the presence. It is however remained as a supplementary role of stationed TV. It is necessary to find an additional business model as a new media to acquire surplus escaping from the deficit of the present T-DMB service. In the present paper, data service of T-DMB is proposed as candidate of such solution. Especially, TTI(Traffic and Travel Information) service is proposed as a killer application using TPEG(Transport Protocol Experts Group). At present, TPEG has not been so popular in the sense of various user satisfaction. Thus the variety of service including bi-directional service using DMB2.0 as in the sphere of Web2.0 is necessary for the service providers. In the paper, the restriction of TPEG-POI(Point of Interest) application service using the conventional mobile communication infrastructure is indicated. To overcome such restriction, TPEG-UCM(User Created Message) application service model using individual bi-directional media which is initiated and interacting by the users is proposed. In the experiment, the application program shows the usability of the proposed method so that the implementation results show its operability.