• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.04a
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• pp.200-200
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• 1996

간재생 및 만성 간질환모델에 대한 인진호 추출분획의 간장 약효검색 방법 1. 간세포 재생능력에 대한 효과 : SD계 수컷 흰쥐(체중 300-350g)를 마취하에서 복부정중선을 따라 개복후 간의 중앙엽 및 좌측엽을 절제하여 봉합하고 수술조작을 끝낸 추 4시간, 익일부터 7일간 오후 5시에 약물을 경구투여하고 마지막투여 후 20시간 절식, 부검하여 간재생률 및 BSP 정체율을 측정하였다. 2. $CCl_4$ 만성간장해 모델에 대한 효자 SD계 수컷 흰쥐(체중 200-250g)에 $CCl_4$ : olive oil 40%용액을 0.5 $m\ell$/kg b.wt. 용량으로 6일간 결구투여 한 후 7일째부터 매일 시험약물을 $CCl_4$ 혼합액 투여 4시간전 및 4시간후에 2회 경구투여하였으며 이 조작을 8일간 하고 마지막 투여 24시간 후에 부검하여 혈액내 ALT 및 AST치, 간조직내 total protein, triglyceride 및 hydroxyproline 양을 측정하였으며, 간중량도 측정하였다. 3. 약물투여 음성대조 : 1% CMC-Na 용액(10$m\ell$/kg b.wt.) 양성대조 : silymarin(25mg/kg), DDB(37.5mg/kg) 인진호추출분획 : KP(180mg/kg), PS-1(300mg/kg), PS-2(300mg/kg), EE (500mg/kg ), HH(640mg/kg), BE(1500mg/kg)

• KCID journal
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• v.21 no.1
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• pp.55-63
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• 2014

A sedimentation basin for agricultural water quality improvement was researched to analyze the water quality purification characteristics. The sedimentation basin constructed at the inlet of Gamdon reservoir in Muan-gun, Jeollanam-do was selected as the research field of this study. The surface area of the sedimentation basin is $34,000m^2$, volume is $122,000m^3$, and hydraulic retention time is 0.3hr~7.3day. The average influent loading of SS was 156.6kg-SS/d, and the effluent loading was 67.5kg-SS/d with the average removal rate of 56.9%. The average influent loadings of BOD and COD were 33.0kg-BOD/d and 60.3kg-COD/d respectively, and the effluent loadings were 26.4kg-BOD/d and 48.6kg-COD/d with the average removal rate of 20.1% and 19.3% respectively. Therefore, the results of this study show that a sedimentation basin can purify SS and organic matters. The average influent loadings of T-N and T-P were 28.7kg-TN/d and 2.97kg-TP/d respectively, and the effluent loadings were 16.3kg-TN/d and 1.41kg-TP/d with the average removal rate of 43.0% and 52.6% respectively. In conclusion, the overall results of this study show that a sedimentation basin is a feasible alternative to purify organic matters and nutrients.

• Journal of fish pathology
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• v.25 no.1
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• pp.31-37
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• 2012

The objective of this study was to investigate the antioxidant enzyme (superoxide dismutase, SOD; glutathione, GSH; glutathione peroxidase, GPx) activities in liver and gill of rock bream, Oplegnathus fasciatus fed the experimental diets for 40 days. The experimental diets were prepared by adding with 30, 60 120 and 240 mg/kg to a commercial diet. In the liver, there were significant increases in SOD at 30~240 mg/kg. GPx activities of liver also were significantly increased at 30~120 mg/kg. The increased activities of SOD and GSH in the gills were observed in the 120 and 240 mg/kg, hence, GPx activity of gill exposed to lower concentrations of zinc (60~240 mg/kg) showed significant augmentation.

• Journal of Environmental Health Sciences
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• v.29 no.4
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• pp.42-47
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• 2003

The purpose of this experimental study is to investigate seasonal deposition flux variations of the total dustfall and various inorganic elements in it. Total of 84 dustfall samples were collected from September, 1997 thru August, 1998 at 7 different sites in Kunsan. Each sample was analyzed by an AAS to determine the levels of 5 inorganic elements; Zn, Cd, Cr, Fe and Pb. Deposition fluxes, soluble/total fractions for each element were extensively investigated. Estimated deposition fluxes of dustfall and elements in Kunsan were in the range of 37.5∼45.1 ton/$\textrm{km}^2$/yr for dustfall, 43.5∼81.8 kg/$\textrm{km}^2$/yr for Zn, 6.6∼11.0 kg/$\textrm{km}^2$/yr for Cd, 44.8∼110.0 kg/$\textrm{km}^2$/yr for Cr, 223∼323 kg/$\textrm{km}^2$/yr for Fe, 10.9∼22.3 kg/$\textrm{km}^2$/yr for Pb, respectively. Thus, the estimated average total deposition fluxes of dustfall in Kunsan(376.35 $\textrm{km}^2$) per day were 43.3 ton and 58.6 kg for Zn, 8.9 kg for Cd, 80.6 kg for Cr, 293.8 kg for Fe and 14.1 kg for Pb, respectively.

• Toxicological Research
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• v.32 no.4
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• pp.327-335
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• 2016

This study aimed to evaluate the potential toxicity and safety of ethyl hydrogen adipate (EHA) by determining its effect on the reproductive function and development of Sprague-Dawley (SD) rats at dose levels of 0 (control), 200, 400, and 800 mg/kg/day. One male and five females of the 800 mg/kg/day died. Body weight loss was observed in the males of the 800 mg/kg/day and in females of the 400 and 800 mg/kg/day. In addition, mating indices decreased and pre-implantation loss rates increased in parental animals of the 400 and 800 mg/kg/day. The gestation index decreased in the male and female rats of the 800 mg/kg/day. Moreover, the body weight of the pups from the 800 mg/kg/day group decreased on post-parturition day 4. These results indicated that the no-observed-adverse-effect level of EHA for parental males and females was 400 mg/kg/day and 200 mg/kg/day, respectively, and that for pups was 400 mg/kg/day.

• Toxicological Research
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• v.13 no.3
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• pp.193-196
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• 1997

Matricaria Chammomillal L., Foemiculum Vulgare mill, and Plantago Psylium L. have been screened for their hepato protective activities against liver damge induced by $CCl_4$ intoxication in mice. Hydroalcoholic extractions (2:8) of herbal drugs were concentrated in vacuo and concentrated crude extracts of Matrica Chammomilla L. and Foeniculum Vulgare mill were orally administered at doses of 100 mg/kg, 200 mg/kg, 400 mg/kg, and 800 mg/kg. Plantago Psyllium was given at doses of 50 mg/kg, 100 mg/kg, 200 mg/kg, and 400 mg/kg. Liver protective activities of these herbs were determined after administration of $CCl_4$ Liver size, serum enzyme activities, sleeping time, and histopatology of the liver were examined one hour after administration of $CCl_4$. ALT and AST activities, liver weight and sleeping time decreased in groups that received 400 mg/kg of Matricaria Chammomilla L. or Foeniculum Vulgare. Histological investigation showed significant increase in hepatic cell regeneration and reduction in liver injury. The group that received 100 mg/kg Plantago Psylium showed liver protection but protection was not significant in other doses.

• Journal of Korean Society for Atmospheric Environment
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• v.15 no.3
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• pp.291-303
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• 1999

The purpose of this experimental study is to investigate seasonal deposition flux variations of the total dustfall and various inorganic elements in it. Total of 84 dustfall samples were collected from September, 1997 thur August, 1998 at 7 different sites in Kunsan. Each sample was analyzed by an AAS to determine the levels of 5 inorganic elements Zn, Cd, Cr, Fe and Pb. Deposition fluxes, soluble/total fractions for each element were extensively investigated. Estimated depositon fluxes of dustfall and elements in Kunsan were in the range of 37.5~45.1 ton/$ extrm{km}^2$/yr for dustfall, 43.5~81.8kg/$\textrm{km}^2$/yr for Zn, 6.6~11.0kg/$\textrm{km}^2$/yr for Cd, 44.8~110.0kg/$\textrm{km}^2$/yr for Cr, 223~323 kg/$\textrm{km}^2$/yr for Fe, 10.9~22.3 kg/$\textrm{km}^2$/yr for Pb, respectively. Thus, the estimated average total deposition fluxes of dustfall in Kunsan(376.35$\textrm{km}^2$) per day were 43.3 ton and 58.6 kg for Zn, 8.9 kg for Cd, 80.6 kg for Cr, 293.8 kg for Fe and 14.1 kg for Pb, respectively.

• Journal of The Korean Society of Agricultural Engineers
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• v.46 no.2
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• pp.107-114
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• 2004

NPS pollutant loads from sandy clayey and clayey loam runoff plots were measured. Runoff plots were 2$\times$10 m in size and 8~10% in slope and paddy area was 4,620 $m^2$. Soybean, corn, tobacco and control (natural weed) were cultured. Precipitation during the growing season of June to October, 2002 was 869.5 mm. Runoff and water quality were measured more than 10 times during the measurements depending on the growing stage. Pollutants loads were estimated by using respective concentration and runoff volume. Runoff occurred when daily rainfall exceeded about 30 mm. The largest runoff was observed from the paddy but pollutant loads were larger from upland crops than those from paddy. SS loads from paddy and upland were 1.4 ton/ha/yr and 3.1~4.3 ton/ha/yr, respectively. COD loads 30 kg/ha/yr and 66~90 kg/ha/yr, T-N loads 13 kg/ha/yr and 14~23 kg/ha/yr, T-P loads 1 kg/ha/yr와 4 kg/ha/yr, nitrate nitrogen loads 1 kg/ha/yr and 4~8 kg/ha/yr, and phosphate phosphorus loads 0 kg/ha/yr and 4~6 kg/ha/yr, respectively. It was concluded that NPS pollutant loads from upland crop culture have greater impact on the quality of the receiving water body than those from paddy culture.

• Physical Therapy Korea
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• v.14 no.2
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• pp.61-67
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• 2007

The purpose of this study was to examine inter- and intra-examiner reliability of the sacroiliac joint (SIJ) anatomical landmarks palpation. Two physical therapists and one doctor specializing in rehabilitation examined 22 asymptomatic subjects. They examined anterior superior iliac supine (ASIS), posterior superior iliac supine (PSIS) and iliac crest (IC). For the assessment of intra-examiner reliability, 3 examiners repeated the measurements 3 times over a 2-week interval. Kappa (Kg) yielded intra-examiner reliability that ranged between slight to fair for the ASIS (Kg=.06 to .26; mean Kg=.19), and slight for the PSIS(Kg=-.04 to .18; mean Kg=.07) and slight to fair for the IC (Kg=.06 to .32; mean Kg=.21). Inter-examiner reliability was slight (ASIS Kg=.13; PSIS Kg=.05; IC Kg=.14). These results suggest that the reliability of the assessing SIJ anatomical landmarks using palpation and observation as an indication of SIJ dysfunction still remains questionable. Before this test can be relied upon as an accurate indicator of SIJ dysfunction, it must undergo further research. This further research needs to examine not only reliability, but also validity, sensitivity and specificity.

• Food Science and Preservation
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• v.5 no.2
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• pp.123-126
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• 1998

This study was carried out investigate to optimum levels of nitrogen and phosphate fertilizer to get a higher yield and a quality of an onion(Allium Cepa L.) from 1993 to 1994. Three fertilizer levels were applied with 120, 240 and 360kg/ha of nitrogen and 100, 200 and 300kg/ha of P2O5 during the onion growing season. After harvesting the onion, it was storaged at given deposit. The growth and yield of the onion were better at the fertilizer levels of both 240 and 360kg/ha of nitrogen and of both 200 and 300kg/ha of P2O5 than at the level of 120kg/ha in nitrogen and 100kg/ha of P2O5. The content of total nitrogen and P2O5 in plant was decreased with reduced application levels of nitrogen and phosphate fertilizer. The rotting rate was higher at the levels of both 360kg/ha in nitrogen and 300kg/ha in P2O5 than the other treatment during the storage period. The sprouting rate tended to be high at 240kg/ha of nitrogen and 100kg/ha of P2O5.