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A Literature Analysis on Medicinal Use and Research of Cannabis in the Meiji Era of Japan

  • Ahn, Byung-Soo;Kang, Seokhyun;Lee, Kyung Hoon;Kim, Seoyoon;Park, Jin Sung;Seo, Hyung-Sik
    • Journal of Pharmacopuncture
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    • v.23 no.3
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    • pp.142-157
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    • 2020
  • Cannabis is a historical plant which has been used as a medicine in East Asia. These days, there are active debates about using cannabis in clinical field. Collecting and comparing cannabis research articles which had been published in the Opening of Japan to spot the interactions between the traditional medicine of Japan, Rangaku which was established in Edo Period and the European medicine which is transferred after Perry Expedition is academically meaningful. This study searched publications, which were listed on Open-Access databases by Dec. 11th, 2019. We collected research articles which had been published from January 3rd, 1867 to July 30th, 1912 also known as Meiji era and uploaded on OpenAccess databases. Our searching databases were J-stage, CiNii (Scholarly and Academic Information Navigator), Tokyo Metropolitan Library, The National Diet Library, IRDB (Institutional Repositories DataBase) and KAKEN (Grant-in-Aid for Scientific Research Database). Searching keywords were cannabis, hemp and all their Japanese synonyms and available combinations. We selected final 15 studies which met every selection criteria in the 346,393 collected studies. Cannabis was prescribed in Meiji era of Japan to alleviate pain and cure the digestive, respiratory, urinary, and nervous system diseases such as indigestion, asthma, tuberculosis, gonorrhea and its complications, insomnia, and nervous prostration. Cannabis was medically used in Meiji era of Japan and the reporting and sharing of its clinical effect was published on the medical journals like present days. There were already Cannabis regulations in that era, but its medicinal use was more liberated than nowadays. It may be a chance to reconsider the current legal system, which strictly controls the use of Cannabis.

Analysis of Clinical Researches on Traditional Medicine Treatment for Behcet's Disease in Korea, China, and Japan (한중일의 베체트병에 대한 한의약 임상연구 분석)

  • Yong, Seokil;Gu, Hyungyung;Kim, Daehun;Sohn, Kyungwoo;Yun, Youngju
    • Journal of Society of Preventive Korean Medicine
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    • v.18 no.1
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    • pp.67-82
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    • 2014
  • Objective : To find a treatment strategy, this study aimed to review and compare the clinical studies of Korea, China, and Japan on traditional medicine treatment for Behcet's disease. Method : Literature searches were performed on six databases in each country and English databases, such as OASIS, KoreanTK, CNKI, J-STAGE, PubMed, and Cochrane CENTRAL. In addition, using the limited keywords, the area was restricted to traditional medicine treatment, but the period was not limited. Studies were categorized according to the study design and we analyzed the difference of treatment among three countries. Results : One hundred and forty-one clinical studies met our inclusion criteria: 11 studies in Korea, 15 in Japan, 115 in China. Randomized controlled trials (RCT) have increased in China, however, no RCT was reported in Korea and Japan. The method of treatment was mainly traditional herbal medicine in all the three countries, but there were significant differences in the field of syndrome identification and prescription among countries. The studies in China made use of most various treatment modalities and reported the highest effectiveness. Conclusion : Traditional medicine treatment showed a considerable effect for improving various symptoms of Behcet's disease. However, more research for answering the safety and well-designed studies considering characteristics of Behcet's disease should be performed to evaluate the effectiveness of traditional medicine treatment objectively in the future.

KR-WordRank : An Unsupervised Korean Word Extraction Method Based on WordRank (KR-WordRank : WordRank를 개선한 비지도학습 기반 한국어 단어 추출 방법)

  • Kim, Hyun-Joong;Cho, Sungzoon;Kang, Pilsung
    • Journal of Korean Institute of Industrial Engineers
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    • v.40 no.1
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    • pp.18-33
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    • 2014
  • A Word is the smallest unit for text analysis, and the premise behind most text-mining algorithms is that the words in given documents can be perfectly recognized. However, the newly coined words, spelling and spacing errors, and domain adaptation problems make it difficult to recognize words correctly. To make matters worse, obtaining a sufficient amount of training data that can be used in any situation is not only unrealistic but also inefficient. Therefore, an automatical word extraction method which does not require a training process is desperately needed. WordRank, the most widely used unsupervised word extraction algorithm for Chinese and Japanese, shows a poor word extraction performance in Korean due to different language structures. In this paper, we first discuss why WordRank has a poor performance in Korean, and propose a customized WordRank algorithm for Korean, named KR-WordRank, by considering its linguistic characteristics and by improving the robustness to noise in text documents. Experiment results show that the performance of KR-WordRank is significantly better than that of the original WordRank in Korean. In addition, it is found that not only can our proposed algorithm extract proper words but also identify candidate keywords for an effective document summarization.

A Study on Interior Wall Color based on Measurement of Emotional Responses (감성 측정에 따른 실내 벽면 색채에 관한 연구)

  • Kim, Ju-Yeon;Lee, Hyun-Soo
    • Science of Emotion and Sensibility
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    • v.12 no.2
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    • pp.205-214
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    • 2009
  • This paper addresses analyzing affective color data for emotional interior design. Both the physical and psychological patterns for spatial colors were tested on thirty subjects, of which fifteen were male. All subjects participated in both the physiological and psychological experiments. The data on the reflecting subjects' affective moods is gathered through EEG physical experiments and SD (Semantic Differential Scale) method surveys. This research has suggested the relation of both experiments through affective color response. The methods of SPSS 10.0 and TeleScan Version 2 are used for analyzing response data to coordinate the colour palette with changeable moods. From the analysis of statistical data, all of the visual stimuli related emotional keywords and physiological responses. Finally, the initial goal of this research is to construct an affective colour database that is tested through human color perception by physical and psychological experiments.

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A Study on Library 3.0 Concept and its Service Model (도서관 3.0의 개념과 서비스 모형에 관한 연구)

  • Noh, Young-Hee
    • Journal of the Korean Society for information Management
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    • v.27 no.4
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    • pp.283-307
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    • 2010
  • Recently the concept of Library 3.0 and its substance have been discussed by scholars and specialists along with Web 3.0. This study aims to analyze the debates on Library 3.0 and review the concept of Library 3.0. In addition, this study proposes library 3.0 service model based on its analysis. The keywords of in the proposed Library 3.0 model in this study is the Social Semantic Digital Library(SSDL), the Linked Library, and the Mobile Library. First, the SSDL means a real knowledge sharing and cooperation by applying both semantic web technology that which can manage data by machines and social networking services into e-libraries. Second, the Linked Library indicates that library resources become linked data that link libraries in all over the world. Finally, the Mobile Library refers to ubiquitous library equipped with RFID and mobile technology.

The Emotional Labor Status and Improvement Plans of Nurses Working in the Integrated Nursing Service Ward: Applying Focus Group Interviews (간호⋅간병통합서비스 병동 간호사의 감정노동 파악 및 개선방안: 초점집단인터뷰 적용)

  • Kim, Chan Hee;Lee, Seon Heui
    • Journal of East-West Nursing Research
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    • v.27 no.2
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    • pp.104-113
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    • 2021
  • Purpose: The purpose of this study was to investigate the status of emotional labor of nursing personnel working in comprehensive nursing service ward and to suggest the way service improvement can be achieved. Methods: A total of 28 nurses working in comprehensive nursing service ward were divided into four groups to conduct focus group interview. All interviews were recorded and transcribed after the interview to perform data analysis in the order of data classification, topic categorization, and keyword derivation. Results: The five categories of subjects and relating keywords drawn from the focus group interviews are as follows: 1) Emotional labor experience: suppressing emotions, expressing emotions or actions that are different from reality, 2) Situations of emotional labor: verbal abuse and assault, sexual harassment, personal needs and errands, 3) Responses to emotional labor: responding directly, responding directly, receiving senior's help, using the organizational system, persevering, 4) Problems caused by emotional labor: work exhaustion, job change intention, job stress, 5) Protection plan against emotional labor: manual or education for nurses, education for patients and carers, compensation, tough sanctions though system strengthening. Conclusion: This study shows that although nurses working in comprehensive nursing service ward generally experience high levels of emotional labor, the problem solving of them relies mainly on personal response. Therefore, it is necessary to develop various measures to protect nurses in an organizational level response, thus to improve the comprehensive nursing service system.

Strengthening BCP for the Prevention of Infectious Diseases in Companies (기업의 감염병 예방을 위한 BCP 강화방안 연구)

  • Kim, Young-Kook;Jeong, Kyung-Ok;Yang, Kyung-Ah
    • Journal of the Korea Safety Management & Science
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    • v.23 no.3
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    • pp.11-18
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    • 2021
  • As the number of confirmed cases of Covid-19 is not decreasing, it is time for domestic companies to respond preemptively and in terms of business continuity. The purpose of this study is to present measures to strengthen BCP to prevent infectious diseases in the enterprise. In this work, three methods of data investigation are used. The first was to search for keywords in academic databases such as the National Assembly Library and the Korea Research and Information Service to investigate degree papers and academic papers. Second, we investigated literature such as research reports, manuals, and guidelines on infectious diseases. Finally, the researchers visited official websites such as KDCA, MOHW, and MOIS to collect and analyze recent data. BCP In view of the Board, a new risk analysis should be made and a disaster preparedness system tailored to the characteristics of the entity should be established. We need to analyze corporate weaknesses and focus on safety culture. It is also important to look at how customers choose their services and products. Based on this, differentiated service strategies should be presented. It is hoped that the results of this study can be used as basic data for companies that want to systematically manage and operate BCP to prevent infectious diseases.

Review Study on the Measurement Tools of Scoliosis: Mainly on Non-radiological Methods (척추측만증 평가 척도에 관한 문헌 고찰: 비방사선 방법을 중심으로)

  • Kim, Dong-Joo;Choi, Seong-Kyeong;Jo, Hyo-Rim;Ha, Yu-bin;Choi, Sung-Hwan;Park, Seo-Hyun;Lee, Seung Deok;Keum, Dong-Ho;Sung, Won-Suk;Kim, Eun-Jung
    • The Journal of Korean Medicine
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    • v.42 no.1
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    • pp.75-98
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    • 2021
  • Objectives: The purpose of this study is to investigate the characteristics, validity, and reliability of non-radiological assessment tools of scoliosis that have been studied so far. Methods: Electronic databases including Pubmed, Cochrane Library, CNKI, Science On, RISS, OASIS were searched by keywords including 'scoliosis assessment', 'scoliosis screening', 'physical examination', 'functional measurement', 'photography', and 'smartphone'. Results: 32 articles using radiation-free assessments were identified from 1,011 records. The mostly used non-radiological methods were Surface topography, Scoliometer, Ultrasound, Digital Infrared Thermal Imaging, and Photography. The other methods were Gait analysis, 3D depth sensor imaging, and Low intensity electromagnetic scan. Conclusions: It was found that non-radiological assessment tools might reduce the number of radiographs taken in scoliosis patients. To increase the reliability and validity, further research on the measurement tools of scoliosis will be needed.

The Protective Effect of Maternal Folic Acid Supplementation on Childhood Cancer: A Systematic Review and Meta-analysis of Case-control Studies

  • Ismail, Wan Rosmawati Wan;Rahman, Raudah Abdul;Rahman, Nur Ashiqin Abd;Atil, Azman;Nawi, Azmawati Mohammed
    • Journal of Preventive Medicine and Public Health
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    • v.52 no.4
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    • pp.205-213
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    • 2019
  • Objectives: Maternal folic acid supplementation is considered mandatory in almost every country in the world to prevent congenital malformations. However, little is known about the association of maternal folic acid intake with the occurrence of childhood cancer. Hence, this study aimed to determine the effects of maternal folic acid consumption on the risk of childhood cancer. Methods: A total of 158 related articles were obtained from PubMed, Google Scholar, Scopus, and ProQuest using standardized keywords, of which 17 were included in the final review. Results: Eleven of the 17 articles showed a significant protective association between maternal folic acid supplementation and childhood cancer. Using a random-effects model, pooled odds ratios (ORs) showed a protective association between maternal folic acid supplementation and childhood acute lymphoblastic leukaemia (OR, 0.75; 95% confidence interval [CI], 0.66 to 0.86). However, there was no significant association between maternal folic acid supplementation and acute myeloid leukaemia (OR, 0.70; 95% CI, 0.46 to 1.06) or childhood brain tumours (OR, 1.02; 95% CI, 0.88 to 1.19). Conclusions: Maternal folic acid supplementation was found to have a protective effect against childhood acute lymphoblastic leukaemia. Thus, healthcare professionals are recommended to provide regular health education and health promotion to the community on the benefits of folic acid supplementation during pregnancy.

Systematic Review on the Efficacy and Safety of Erenumab for the Prevention of Migraine (편두통 예방을 위한 erenumab의 유효성 및 안전성에 관한 체계적 고찰)

  • Son, Pyoungwoo;Chae, Hyunwoo;Ji, Eunhee;Yoo, Bong Kyu
    • Korean Journal of Clinical Pharmacy
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    • v.29 no.2
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    • pp.71-78
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    • 2019
  • Objective: This study aimed to provide efficacy and safety information on the use of erenumab for prevention of episodic and chronic migraines. Methods: The keywords "Erenumab and migraine" were used to search the PubMed database to then compile efficacy and safety data for erenumab. Data from relevant Phase 2 and Phase 3 clinical trials were analyzed, using RevMan for statistical analysis. Results: Three clinical trials (one Phase 2 and two Phase 3 studies) were retrieved. All three trials used the same primary endpoint (change from baseline in monthly migraine days (CBMD)) to evaluate efficacy and safety of erenumab use for prevention of episodic and chronic migraines. Subcutaneous doses of erenumab (70 or 140 mg) were administered monthly in each trial, for 3 months (Studies 2, and 3) or 6 months (Study 1). The mean differences in CBMD in the 70 mg and 140 mg erenumab arms were -1.36 and -1.98, respectively, compared to that in the placebo arm. Some adverse events, such as nasopharyngitis and upper respiratory tract infection, were reported, but no differences in safety between erenumab and placebo were found to be significant. Conclusions: Erenumab showed superior efficacy in prevention of migraines compared to placebo. However, additional information regarding the long-term safety of erenumab should be collected. Therefore, post-marketing surveillance for adverse events is needed.