• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2002년도 Proceedings of the International Welding/Joining Conference-Korea
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• pp.639-643
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• 2002

The main purpose of this study was to investigate the formation mechanisms of imperfections such as irregular humps, outer cavity and inner cavity in the laser fusion zone of diamond saw blade. Laser beam welding was conducted to join two parts of blade; mild steel shank and Fe-Co-Ni sintered tip. The variables were beam power and travel speed. The microstructure and elements distributions of specimens were analyzed with SEM, AES, EPMA and so on. It was found that these imperfections were responded to heat input. Irregular humps were reduced in 10.4∼17.6kJ/m heat input range. However there were no clear evidences, which could explain the relations between humps formation and heat input. The number of outer cavity and inner cavity decreased as heat input was increased. Considering both possible defects formations mechanisms, it could be thought that outer cavity was caused by insufficient refill of keyhole, which was from rapid solidification of molten metal and fast molten metal flow to the rear keyhole wall at low heat input. More inner cavities were found near the interface of the fusion zone and sintered segment and in the bottom of the fusion zone. Inner cavity was mainly formed in the upper fusion zone at high heat input whereas was in the bottom at low heat input. Inner cavity was from trapping of coarsened preexist pores in the sintered tip and metal vapor due to rapid solidification of molten metal before the bubbles escaped.

• Spatial Information Research
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• 제18권4호
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• pp.141-149
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• 2010

최근 웹 GIS에 있어 큰 흐름 중의 하나는 오픈소스 소프트웨어 (Free and Open Source Software: FOSS)를 이용한 시스템 구축이다. 지리정보를 웹에서 처리하는데 있어서 오픈소스 소프트웨어의 등장은 기존 상용소프트웨어의 기술에 의존하지 않으면서, 구현모듈의 재사용과 시스템 확장성을 증대시키고 있다. 본 연구에서는 오픈소스 공간데이터베이스인 PostgreSQL/PostGIS와 동적상호작용을 지원하는 구글어스를 이용하여 지리정보의 효율적인 사각화를 위한 웹기반의 지리정보 표출시스템을 설계 및 구현하였다. 본 시스템의 지도 시각화는 구글어스 플러그인 및 API(application programming interface)를 이용하여 구현하였으며, 사용자의 요구에 따라 동적으로 데이터를 KML(Keyhole Markup Language)로 자동 생성하여 구글어스 상에 다양한 지리적 형태로 시각화 할 수 있는 자바 모듈(KML Generator)을 구현하였다. 프로토타입 시스템은 우리나라의 LAI(leaf area index), 임상도 및 정곡생산량 데이터를 이용하여 테스트되었으며 본 연구에서 설계 및 구현된 웹기반의 지리정보 표출 시스템이 다양한 지리공간데이터의 시각화에 적용될 수 있는 가능성을 제시하였다.

• 대한후두음성언어의학회지
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• 제19권1호
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• pp.11-15
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• 2008

Endoscopic laser cordectomy is known as an oncologically sound procedure for T1 and selected T2 glottic carcinoma ; it has comparable local control rate and better long-term laryngeal preservation rate when compared with those of radiotherapy. Even if results of the reported voice outcome studies after surgery or radiotherapy are diverse and controversial, resection deeper than the body layer of the vocal fold (type III, IV, V cordectomy) usually leads to aerodynamic insufficiency during phonation and results in poor voice quality. A keyhole defect or development of synechiae at the anterior commissure after type VI cordecomy may also result in unsatisfactory vocal outcome. However, many advances in phonosurgical techniques are reported to be successfully applied in the reconstruction of glottal defect that is subsequent to endoscopic laser cordectomy. In case of glottal insufficiency, voice restoration can be achieved by means of augmentation of the paraglottic space or medialization of the excavated vocal fold. Injection laryngoplasty with synthetic materials or autologous fat is gaining its popularity for restoring minor glottal volume defect because of its convenience. Laryngeal framework surgery, especially type I thyroplasty with premade implant systems or Gore-Tex, is most frequently used to correct larger glottic volume defect. In case of anterior commissural keyhole defect, additional procedure including laryngofissure may be required. For anterior commissural synechiae, laryngeal keel may be inserted for several weeks or mitomycin-C may be repeatedly applied after the division of adhesive scar to prevent restenosis. In this paper, current concepts and the authors' experiences of phonosurgical reconstruction of vocal function after endoscopic cordectomy will be introduced.

• 지질공학
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• 제13권4호
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• pp.475-490
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• 2003

본 연구는 물리탐사방법 중 GPR을 이용한 고고학에서의 활용 가능성을 제시하기 위한 것이다. 따라서 탐사의 결과를 보고 고고학자들이 직접 발굴에 응용하여 발굴로 검증된 예만을 제시하였다. 탐사지역으로는 강원도 원주시 부론면 법천리 고분군, 경상남도 고성군 송학동 1호분, 그리고 일본의 사가현에 위치한 요시노가리 옹관유적이다. GPR 탐사의 time slice 분석법을 유구의 평면적인 분포양상을 파악하는데 이용하였다. 이 탐사법으로 각 유적지에서 이상반응(Anomaly)을 찾을 수 있었으며 지하의 각 깊이별 문화유적 분포양상의 변화를 살펴볼 수 있었다. 원주 법천리 유적에서는 석실 및 기타 석재 유구들이 GPR에 대하여 강한 반사신호를 나타내어 백제시대 유구의 분포상황을 확인할 수 있었다. 또한 고성 송학동 1호분은 그동안 고고학계에 논란이 되어왔던 전방후원분의 진위여부에 대하여 탐사 및 발굴을 통하여 3개의 분묘가 합쳐진 것으로 들어났다. 특히 일본의 요시노가리 유적의 2열 옹관 매장지는 발굴을 GPR탐사로 대신한 좋은 예이다. 이상의 조사에서 GPR탐사를 이용하여 유구의 분포범위 및 양상을 발굴 전에 미리 확인할 수 있었다.

• International Journal of Korean Welding Society
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• 제2권1호
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• pp.21-24
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• 2002

The main purpose of this study was to investigate the formation mechanisms of imperfections such as irregular humps, outer cavity and inner cavity in the laser fusion zone of diamond saw blade. Laser beam welding was conducted to join two parts of blade; mild steel shank and Fe-Co-Ni sintered tip. The variables were beam power and travel speed. The microstructure and elements distributions of specimens were analyzed with SEM, AES, EPMA and so on. It was found that these imperfections were responded to heat input. Irregular humps were reduced in 10.4∼l7.6kJ/m heat input range. However there were no clear evidences, which could explain the relations between humps formation and heat input. The number of outer cavity and inner cavity decreased as heat input was increased. Considering both possible defects formations mechanisms, it could be thought that outer cavity was caused by insufficient refill of keyhole, which was from rapid solidification of molten metal and fast molten metal flow to the rear keyhole wall at low heat input. More inner cavities were found near the interface of the fusion zone and sintered segment and in the bottom of the fusion zone. Inner cavity was mainly formed in the upper fusion zone at high heat input whereas was in the bottom at low heat input. Inner cavity was from trapping of coarsened preexist pores in the sintered tip and metal vapor due to rapid solidification of molten metal before the bubbles escaped.

• 생명과학회지
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• 제30권10호
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• pp.905-911
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• 2020

본 연구에서는 Keyhole limpet hemocyanin (KLH)에 대한 체액성 및 세포성 면역반응 유도에 대한 PAMAM dendrimer G4 (PAMAM)의 증강 효과를 조사하였다. PAMAM을 KLH와 2주 간격으로 2회 피하주사로 면역한 후, KLH에 대한 특이항체를 측정한 결과, KLH+PAMAM 면역 그룹은 KLH만을 단독으로 면역한 그룹에 약 30배이상 높은 유의한 항체가(IgG+IgA+IgM) 상승을 나타냈다. ELISA 분석에 의해 KLH 특이적인 면역글로부린의 isotype을 측정한 결과, PAMAM를 혼합하여 면역함으로서 IgG1, IgG2a, IgG2b, IgG3 및 IgM 항체의 역가가 유의하게 증가하는 것으로 확인되었다. 또한 면역 개시 7주째에 면역동물에 KLH 항원을 피하주사하고 swelling reaction을 통해 세포성 면역반응인 지연형 과민반응(DTH)을 측정한 결과, KLH+PAMAM으로 면역한 그룹에서 KLH만을 단독으로 면역한 그룹에 비해 높은 DTH 유도활성이 관찰되었다. 한편 면역동물의 비장세포를 취하여 in vitro에서 KLH로 재자극한 후 림프구 증식반응과 사이토카인 유도활성을 측정한 결과, PAMAM을 혼합하여 면역한 그룹에서 KLH 단독 면역 그룹에 비해 림프구의 증식반응에 유의하게 증가하였으며, Th1 type (IFN-γ)과 Th2 type (IL-4) 사이토카인의 생성도 모두 상승하는 것으로 확인되었다. 이상의 결과로부터 PAMAM dendrimer는 함께 투여된 항원물질에 의해 유도되는 세포성 면역과 체액성 면역을 상승시키는 활성이 있는 것으로 확인되었으며, 이는 PAMAM dendrimer가 면역 adjuvant로서 응용 가능한 소재임을 입증하는 것이다.

• 한국레이저가공학회지
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• 제1권1호
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• pp.30-38
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• 1998

This study includes the efface of shielding gas types on $CO_2$ laser weldability of low carbon automotive galvanized steel. The types of shielding gas evaluated are He, $CO_2$, Ar, $N_2$, 50%Ar＋50%$N_2$. The weld penetration, strength, formability(Erichsen test) of Laser weld are found to be strongly dependent upon the types of shielding gas used. Further, the maximum travel speed and flow rate to form a keyhole weld is also dependent upon types of shielding gas. The ability of shielding gas in removing plasma plume and thus increasing weld penetration is believed to be closely related with ionization/dissociation potential, which determine the period of plasma formation and disappearance. Further, thermal conductivity and reactivity of gas with molten pool also give strong effect on penetration and porosity formation which in turn affect on the formability and strength.

• Asian-Australasian Journal of Animal Sciences
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• 제15권3호
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• pp.432-437
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• 2002

Immunosuppressive potential of 65 kDa buffalo placental protein (bPP65) on B-cell proliferation in vitro and antibody response in vivo was evaluated. B-cell proliferation was estimated by measuring incorporation of tritiated thymidine in buffalo lymphocytes while primary antibody responses against phytohaemagglutinin (PHA) or keyhole limpet haemocyanin (KLH) were evaluated in mice. bPP65 suppressed proliferation of lipopolysaccharide (a B-cell specific mitogen)-stimulated buffalo lymphocytes in vitro indicating suppression of B-cells. This suppression was dose dependent over the protein concentration range $25-100 {\mu}g/ml$. Primary antibody responses in mice against PHA and KLH in presence of bPP65 were lower as compared to in its absence but these were not statistically significant. Amino acid composition data of bPP65 and BSA suggested that bPP65 is different from BSA.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 추계학술대회논문집A
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• pp.791-796
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• 2001

Welding using lasers can be mass-produced in high speed. In the laser welding, performing real-time evaluation of the welding quality is very important in enhancing the efficiency of welding. In this study, the plasma and molten metal which are generated during laser welding were measured using the UV sensor and IR sensor. The results of laser welding were classified into five categories such as optimal heat input, little low heat input, low heat input, focus off, and nozzle change. Also, a system was formulated which uses the measured signals with a fuzzy pattern recognition method which is used to perform real-time evaluation of the welding quality and the defects which can occur in laser welding. Weld quality prediction program was developed using previous weld results and statistical program which could show the trend of weld quality and signal was developed.

• 한국공작기계학회논문집
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• 제12권6호
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• pp.14-21
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• 2003

With the increased use of lasers in industrial welding applications, techniques for monitoring and controlling these processes become increasingly important. It is very important that we understand the dynamic behaviors of the laser induced Plume in welding, because the laser induced plume has considerable effects on welding efficiency and the quality of materials. As the plume fluctuation was associated with keyhole instability, unstable vapor plume indicated the process was unstable and would result in poor welds. An Infrared Thermal-vision Camera can be utilized compensate for incurracies encountered in real-time monitoring during laser welding. We have results that instabilities of plume are closely related with hot cracking and defect of laser welding.