• Title/Summary/Keyword: Key chain

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Effects of dietary valine:lysine ratio on the performance, amino acid composition of tissues and mRNA expression of genes involved in branched-chain amino acid metabolism of weaned piglets

  • Xu, Ye Tong;Ma, Xiao Kang;Wang, Chun Lin;Yuan, Ming Feng;Piao, Xiang Shu
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.1
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    • pp.106-115
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    • 2018
  • Objective: The goal of this study was to investigate the effects of dietary standard ileal digestible (SID) valine:lysine ratios on performance, intestinal morphology, amino acids of liver and muscle, plasma indices and mRNA expression of branched-chain amino acid (BCAA) metabolism enzymes. Methods: A total of 144 crossbred pigs (Duroc${\times}$Landrace${\times}$Large White) weaned at $28{\pm}4days$ of age ($8.79{\pm}0.02kg$ body weight) were randomly allotted to 1 of 4 diets formulated to provide SID valine:lysine ratios of 50%, 60%, 70%, or 80%. Each diet was fed to 6 pens of pigs with 6 pigs per pen (3 gilts and 3 barrows) for 28 days. Results: Average daily gain increased quadratically (p<0.05), the villous height of the duodenum, jejunum and ileum increased linearly (p<0.05) as the SID valine:lysine ratio increased. The concentrations of plasma ${\alpha}-keto$ isovaleric and valine increased linearly (p<0.05), plasma aspartate, asparagine and cysteine decreased (p<0.05) as the SID valine:lysine ratio increased. An increase in SID lysine:valine levels increased mRNA expression levels of mitochondrial BCAA transaminase and branched-chain ${\alpha}-keto$ acid dehydrogenase in the longissimus dorsi muscle (p<0.05). Conclusion: Using a quadratic model, a SID valine:lysine ratio of 68% was shown to maximize the growth of weaned pigs which is slightly higher than the level recommended by the National Research Council.

Branched-chain Amino Acids Reverse the Growth of Intrauterine Growth Retardation Rats in a Malnutrition Model

  • Zheng, Chuan;Huang, Chengfei;Cao, Yunhe;Wang, Junjun;Dong, Bing
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.11
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    • pp.1495-1503
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    • 2009
  • This experiment was conducted to determine the effect of dietary supplementation with BCAA (branched-chain amino acids: leucine, isoleucine and valine) on improving the growth of rats in a malnutritional IUGR (Intrauterine Growth Retardation) model, which was established by feeding restriction. In the experimental treatment, rats were fed purified diets supplemented with BCAA (mixed) during the whole gestation period, while arginine and alanine supplementation were set as the positive and negative control group, respectively. The results showed that, compared to the effect of alanine, BCAA reversed IUGR by increasing the fetus weights by 18.4% and placental weights by 18.0% while fetal numbers were statistically increased. Analysis of gene and protein expression revealed that BCAA treatment increased embryonic liver IGF-I expression; the uterus expressed higher levels of estrogen receptor-$\alpha$ (ER-$\alpha$) and progesterone receptor (PR), and the placenta expressed higher levels of IGF-II. Amino acid analysis of dam plasma revealed that BCAA supplementation effectively enhanced the plasma BCAA levels caused by the feed restriction. BCAA also enhanced the embryonic liver gluconeogenesis by augmenting the expression of two key enzymes, namely fructose-1,6-biphosphatase (FBP) and phosphoenolpyruvate carboxykinase (PEPCK). In conclusion, supplementation of BCAA increased litter size, embryonic weight and litter embryonic weight by improving the dam uterus and placental functions as well as increasing gluconeogenesis in the embryonic liver, which further provided energy to enhance the embryonic growth.

Simulation Study of Two Supply Chain Collaboration Programs: Consignment and VMI

  • Ryu, Chung-Suk
    • Journal of Distribution Science
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    • v.14 no.4
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    • pp.21-31
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    • 2016
  • Purpose - This study examines how consignment and Vendor-Managed Inventory perform as supply chain collaboration programs. By using three key collaborative features, this study defines the collaboration programs and develops theoretical models of different supply chain systems. Research design, data and methodology - This study conducts sophisticated analysis on the supply chain systems by applying simulation modeling based on time-phased operations. The simulation model represents a two-stage supply chain system where a supplier sells a single item to a buyer, and it incorporates various operations. Results - In general, the simulation outcomes support that more advanced collaboration programs outperform less advanced ones. The analysis on the simulation outcomes identifies the significant value of information sharing in both collaboration programs. The specific conditions where the particular collaboration system outperforms the others are recognized. Conclusions - The outcome of this study supports that the supply chain system can improve its performance by having more collaborative features. This study provides business practitioners with guidelines to identify the circumstances that the specific collaboration program can fully exploit its advantages.

A fault attack on elliptic curve scalar multiplication based on Euclidean Addition Chain (Euclidean Addition Chain을 사용하는 타원곡선 스칼라 곱셈 연산에 대한 오류 주입 공격)

  • Lee, Soo Jeong;Cho, Sung Min;Hong, Seokhie
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.22 no.5
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    • pp.1019-1025
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    • 2012
  • Fault attacks manipulate the computation of an algorithm and get information about the private key from the erroneous result. It is the most powerful attack for the cryptographic device. Currently, the research on error detection methods and fault attacks have been studied actively. S. Pontarelli et al. introduced an error detection method in 2009. It can detect an error that occurs during Elliptic Curve Scalar Multiplication (ECSM). In this paper, we present a new fault attack. Our attack can avoid the error detection method introduced by S. Pontarelli et al. We inject a bit flip error in the Euclidean Addition Chain (EAC) on the private key in ECSM and retrieve the private key.

Digitization of Supply Chain Management : Key Elements and Strategic Impacts (공급망관리의 디지털화 : 구성요소와 전략적 파급효과)

  • Park, Seong Taek;Kim, Tae Ung;Kim, Mi Ryang
    • Journal of Digital Convergence
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    • v.18 no.6
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    • pp.109-120
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    • 2020
  • The supply chain without digitization is just a series of discrete, siloed steps taken through marketing, product development, manufacturing, and logistics, and finally into the hands of the customer. Digitization brings down those walls, and the chain becomes a completely integrated network fully transparent to all the parties involved. The ulitimate goals of digitizatized supply chain management are velocity and visibility. This network will depend on a number of key technologies including integrated planning and execution systems, supply chain analytics, autonomous logistics, smart warehousing and factory, etc, enabling companies to react to disruptions in the supply chain, and even anticipate them, by fully modeling the network, creating "what-if" scenarios, and adjusting the supply chain in real time as conditions change. This paper presents a number of studies on digitalization of supply chains and provides a discussion on issues raised in the process of technology adoption. Implications of the study findings are also provided.

Isolation and Cloning of Porcine SLC27A2 Gene and Detection of Its Polymorphism Associated with Growth and Carcass Traits

  • Wang, Tao;Liu, Chang;Xiong, Yuan-Zhu;Deng, Chang-Yan;Zuo, Bo;Xie, Hong-Tao;Xu, De-Quan
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.8
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    • pp.1169-1173
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    • 2007
  • The protein encoded by SLC27A2 gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family, and it converts free long-chain fatty acids into fatty acyl-CoA esters, and thereby plays a key role in lipid biosynthesis and fatty acid degradation. In the present study, SLC27A2 located on human chromosome 15 was selected as candidate gene and we isolated and cloned partial fragments of mRNA sequence and genomic fragments of porcine SLC27A2 gene. The coding region of the gene as determined by alignments shared 90% and 82% identity with human and mouse cDNAs, respectively. Detection in LargeWhite and Meishan breeds showed that a single nucleotide polymorphism (SNP) ($A{\rightarrow}G$) existed in exon 7, which caused corresponding amino acid changed for encoding. In LargeWhite pigs it encoded for Val while in Meishan pigs it encoded for Ile, so we developed the PCR-RFLP genotype method for detection of this polymorphism. Association study in 135 $F_2$ reference family indicated that significant correlation existed between the polymorphism and growth and carcass traits.

A Dynamic Analysis on Value Chain Model of E-Commerce - The Case of Online Book Market - (전자상거래의 가치사슬모형에 관한 동태적 분석 - 온라인 서점시장을 중심으로 -)

  • Lee Young-Chan;Seo Chang-Gab
    • Proceedings of the Korea Association of Information Systems Conference
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    • 2004.05a
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    • pp.316-335
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    • 2004
  • This paper builds a system dynamics model analyzing first mover effect and growth strategy of online retailer, a major segment of B2C e-commerce. The dynamic model in this paper is calibrated to the online book market and Yes24.com as major test cases. The model consists of eight key value chain sectors. Five of these(Users, Site Operations, Human Resources, Financial Accounting, and Fundraising) are internal to the company, and three others(Market, Financial Market, and Relative Performance) are external to the company. With the model, this paper suggests research propositions representing positive feedback loops and negative feedback loops that lead to corporate growth and limits to growth according to dynamic causal relationships among eight key value chain sectors, and simulate these propositions.

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Analytic Throughput Model for Network Coded TCP in Wireless Mesh Networks

  • Zhang, Sanfeng;Lan, Xiang;Li, Shuang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.8 no.9
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    • pp.3110-3125
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    • 2014
  • Network coding improves TCP's performance in lossy wireless networks. However, the complex congestion window evolution of network coded TCP (TCP-NC) makes the analysis of end-to-end throughput challenging. This paper analyzes the evolutionary process of TCP-NC against lossy links. An analytic model is established by applying a two-dimensional Markov chain. With maximum window size, end-to-end erasure rate and redundancy parameter as input parameters, the analytic model can reflect window evolution and calculate end-to-end throughput of TCP-NC precisely. The key point of our model is that by the novel definition of the states of Markov chain, both the number of related states and the computation complexity are substantially reduced. Our work helps to understand the factors that affect TCP-NC's performance and lay the foundation of its optimization. Extensive simulations on NS2 show that the analytic model features fairly high accuracy.

Stochastic simulation based on copula model for intermittent monthly streamflows in arid regions

  • Lee, Taesam;Jeong, Changsam;Park, Taewoong
    • Proceedings of the Korea Water Resources Association Conference
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    • 2015.05a
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    • pp.488-488
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    • 2015
  • Intermittent streamflow is common phenomenon in arid and semi-arid regions. To manage water resources of intermittent streamflows, stochactic simulation data is essential; however the seasonally stochastic modeling for intermittent streamflow is a difficult task. In this study, using the periodic Markov chain model, we simulate intermittent monthly streamflow for occurrence and the periodic gamma autoregressive and copula models for amount. The copula models were tested in a previous study for the simulation of yearly streamflow, resulting in successful replication of the key and operational statistics of historical data; however, the copula models have never been tested on a monthly time scale. The intermittent models were applied to the Colorado River system in the present study. A few drawbacks of the PGAR model were identified, such as significant underestimation of minimum values on an aggregated yearly time scale and restrictions of the parameter boundaries. Conversely, the copula models do not present such drawbacks but show feasible reproduction of key and operational statistics. We concluded that the periodic Markov chain based the copula models is a practicable method to simulate intermittent monthly streamflow time series.

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Investigation on Chain Transfer Reaction of Benzene Sulfonyl Chloride in Styrene Radical Polymerization

  • Li, Cuiping;Fu, Zhifeng;Shi, Yan
    • Macromolecular Research
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    • v.17 no.8
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    • pp.557-562
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    • 2009
  • The free radical polymerization of styrene was initiated with azobis(isobutyronitrile) in the presence of benzene sulfonyl chloride. Analysis of the terminal structures of the obtained polystyrene with $^1H$ NMR spectroscopy revealed the presence of a phenyl sulfonyl group at the ${\alpha}$-end and a chlorine atom at the ${\omega}$-end of each polystyrene chain. The terminal chlorine atom in the polystyrene chains was further confirmed through atom transfer radical polymerization (ATRP) of styrene and methyl acrylate using the obtained polystyrenes as macroinitiators and CuCl/2,2'-bipyridine as the catalyst system. GPC traces of the products obtained in ATRP at different reaction times were clearly shifted to higher molecular weight direction, indicating that nearly all the macroinitiator chains initiated ATRP of the second monomers. In addition, the number-average molecular weights of the polystyrenes increased directly proportional to the monomer conversions, and agreed well with the theoretical ones.