• Title/Summary/Keyword: Key Design Parameter

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Morphological Factors and Cardiac Doses in Whole Breast Radiation for Left-sided Breast Cancer

  • Guan, Hui;Dong, Yuan-Li;Ding, Li-Jie;Zhang, Zi-Cheng;Huang, Wei;Liu, Cheng-Xin;Fu, Cheng-Rui;Zhu, Jian;Li, Hong-Sheng;Li, Miao-Miao;Li, Bao-Sheng
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.7
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    • pp.2889-2894
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    • 2015
  • Background: To investigate the impact of the breast size, shape, maximum heart depth (MDH), and chest wall hypotenuse (the distance connecting middle point of the sternum and the length of lung draw on the selected transverse CT slice) on the volumetric dose to heart with whole breast irradiation (WBI) of left-sided breast cancer patients. Materials and Methods: Fifty-three patients with left-sided breast cancer undergoing adjuvant intensity-modulated radiotherapy (IMRT) were enrolled in the study. The primary breast size and shape, MHD and DCWH (chest wall hypotenuse) were contoured on radiotherapy (RT) planning CT slices. The dose data of hearts were obtained from the dose-volume histograms (DVHs). Data were analyzed by one-way analysis of variance (ANOVA), Student's t-test and linear regression analysis. Results: Breast size was independent of heart dose, whereas breast shape, MHD and DCWH were correlated with heart dose. The shapes of breasts were divided into four types, as the flap type, hemisphere type, cone type and pendulous type with heart mean dose being $491.8{\pm}234.6cGy$, $752.7{\pm}219.0cGy$, $620.2{\pm}275.7cGy$, and $666.1{\pm}238.0cGy$, respectively. The flap type of breasts shows a strong statistically reduction in heart dose, compared to others (p=0.008 for V30 of heart). DCWH and MHD were found to be the most important parameters correlating with heart dose in WBI. Conclusions: More attention should be paid to the heart dose of non-flap type patients. The MHD was found to be the most important parameter to correlate with heart dose in tangential WBI, closely followed by the DCWH, which could help radiation oncologists and physicsts evaluate heart dose and design RT plan in advance.

Cyclic performance and design recommendations of a novel weak-axis reduced beam section connection

  • Lu, Linfeng;Xu, Yinglu;Liu, Jie;Lim, James B.P.
    • Steel and Composite Structures
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    • v.27 no.3
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    • pp.337-353
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    • 2018
  • In previous weak-axis moment connection tests, brittle fracture always initiated near the edge of the beam flange groove weld due to force flow towards the stiffer column flanges, which is the opposite pattern as strong-axis moment connections. As part of the China NSFC (51278061) study, this paper tested two full-scale novel weak-axis reduced beam section moment connections, including one exterior frame connection specimen SJ-1 under beam end monotonic loading and one interior frame joint specimen SJ-2 under column top cyclic loading. Test results showed that these two specimens were able to satisfy the demands of FEMA-267 (1995) or ANSI/AISC 341-10 (2010) without experiencing brittle fracture. A parametric analysis using the finite element software ABAQUS was carried out to better understand the cyclic performance of the novel weak-axis reduced beam section moment connections, and the influence of the distance between skin plate and reduced beam section, a, the length of the reduced beam section, b, and the cutting depth of the reduced beam section, c, on the cyclic performance was analyzed. It was found that increasing three parametric values reasonably is beneficial to forming beam plastic hinges, and increasing the parameter a is conducive to reducing stress concentration of beam flange groove welds while increasing the parameters b and c can only reduce the peak stress of beam flange groove welds. The rules recommended by FEMA350 (2000) are suitable for designing the proposed weak-axis RBS moment connection, and a proven calculation formulation is given to determine the thickness of skin plate, the key components in the proposed weak-axis connections. Based on the experimental and numerical results, a design procedure for the proposed weak-axis RBS moment connections was developed.

Deformation analysis of shallow tunneling with unconsolidated soil using nonlinear numerical modeling (비선형 수치모델링을 이용한 미고결 지반 저토피 터널의 변형해석)

  • Lee, Jae-Ho;Kim, Young-Su;Yoo, Ji-Hyeung;Jeong, Yun-Young
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.12 no.2
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    • pp.105-116
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    • 2010
  • The estimation of surface settlement, ground behavior and tunnel displacement are the main factors in urban tunnel design with shallow depth and unconsolidated soil. On deformation analysis of shallow tunnel, it is important to identify possible deformation mechanism of shear bands developing from tunnel shoulder to the ground surface. This paper investigated the effects of key design parameter affecting deformation behavior by numerical analysis using nonlinear model incorporating the reduction of shear stiffness and strength parameters with the increment of the maximum shear strain after the initiation of plastic yielding. Numerical parametric studies are carried out to consider the reduction of shear stiffness and strength parameters, horizontal stress ratio, cohesion and shotcrete thickness.

A study to improve the accuracy of the naive propensity score adjusted estimator using double post-stratification method (나이브 성향점수보정 추정량의 정확성 향상을 위한 이중 사후층화 방법 연구)

  • Leesu Yeo;Key-Il Shin
    • The Korean Journal of Applied Statistics
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    • v.36 no.6
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    • pp.547-559
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    • 2023
  • Proper handling of nonresponse in sample survey improves the accuracy of the parameter estimation. Various studies have been conducted to properly handle MAR (missing at random) nonresponse or MCAR (missing completely at random) nonresponse. When nonresponse occurs, the PSA (propensity score adjusted) estimator is commonly used as a mean estimator. The PSA estimator is known to be unbiased when known sample weights and properly estimated response probabilities are used. However, for MNAR (missing not at random) nonresponse, which is affected by the value of the study variable, since it is very difficult to obtain accurate response probabilities, bias may occur in the PSA estimator. Chung and Shin (2017, 2022) proposed a post-stratification method to improve the accuracy of mean estimation when MNAR nonresponse occurs under a non-informative sample design. In this study, we propose a double post-stratification method to improve the accuracy of the naive PSA estimator for MNAR nonresponse under an informative sample design. In addition, we perform simulation studies to confirm the superiority of the proposed method.

Cost Analysis of Modified Asphalts using a Performance Based Fracture Criterion (공용성에 근거한 파괴기준을 이용한 개질 아스팔트 포장의 비용 효과 분석)

  • Kim, Boo-Il
    • International Journal of Highway Engineering
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    • v.7 no.4 s.26
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    • pp.49-56
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    • 2005
  • The effect of modified asphalts is evaluated by simple comparison of a single parameter (i.e., tensile strength, stiffness, etc.) between modified asphalt mixture and unmodified mixture. The use of a single parameter to evaluate the effect of modified asphalt must be questioned. Rather, a single unified framework that accounts for changes in key mixture properties is needed to effectively evaluate the modified asphalt mixtures. This study used a new performance-based fracture parameter as a single unified framework, the Energy Ratio (ER), for quantifying the effect of modified asphalts oil the fracture resistance of mixtures. The Energy Ratio was then used as a performance criterion for calculating the construction cost of two modified asphalt pavements (SBS and Crumb Rubber) and unmodified asphalt pavement. The results showed that the Energy Ratio of SBS modified asphalt was higher than those of crumb rubber and unmodified asphalt. Cost analyses indicated that the construction cost of the AC layer would be reduced by up to 24% by SBS modification. Based on the results, the Energy Ratio is capable of evaluating the effect of modified mixtures, and may form the basis of a promising fracture criterion for performance-based thickness design in asphalt pavements.

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Design of RFID Authentication Protocol Using 2D Tent-map (2차원 Tent-map을 이용한 RFID 인증 프로토콜 설계)

  • Yim, Geo-su
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.13 no.5
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    • pp.425-431
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    • 2020
  • Recent advancements in industries and technologies have resulted in an increase in the volume of transportation, management, and distribution of logistics. Radio-frequency identification (RFID) technologies have been developed to efficiently manage such a large amount of logistics information. The use of RFID for management is being applied not only to the logistics industry, but also to the power transmission and energy management field. However, due to the limitation of program development capacity, the RFID device is limited in development, and this limitation is vulnerable to security because the existing strong encryption method cannot be used. For this reason, we designed a chaotic system for security with simple operations that are easy to apply to such a restricted environment of RFID. The designed system is a two-dimensional tent map chaotic system. In order to solve the problem of a biased distribution of signals according to the parameters of the chaotic dynamical system, the system has a cryptographic parameter(𝜇1), a distribution parameter(𝜇2), and a parameter(𝜃), which is the constant point, ID value, that can be used as a key value. The designed RFID authentication system is similar to random numbers, and it has the characteristics of chaotic signals that can be reproduced with initial values. It can also solve the problem of a biased distribution of parameters, so it is deemed to be more effective than the existing encryption method using the chaotic system.

Assessment of mulberry leaf as a potential feed supplement for animal feeding in P.R. China

  • Cai, Ming;Mu, Lan;Wang, Zong-li;Liu, Jian-yong;Liu, Tian-liang;Wanapat, Metha;Huang, Bi-zhi
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.8
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    • pp.1145-1152
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    • 2019
  • Objective: Mulberry (Morus alba L.) is a cultivated shrub grown widely in the sub-tropical and tropical areas. It has been shown that mulberry leaf contains high levels of protein while having polyphenols as phytonutrients. Therefore, it is important to conduct an experiment to assess potential toxic level from mulberry on behavior, blood hematological and coagulation parameter using Sprague-Dawley (SD) rats. Methods: Both male and female SD rats were given an intragastric administration of respective treatments of mulberry leaf intakes (control, low and high levels). Parameters of feed intake, hematological and coagulation of blood parameters, as well as liveweight changes were taken during the 7 d of adaptation, 28 d of treatment exposure, and 14 d of recovery periods, respectively. All treatment data were statistically analyzed using analysis of variance of SPSS17.0 for Windows Statistical Software following the Randomized complete block design with sex as a block. Results: Most of the parameters of the physical symptoms of the SD rats, were not significantly different (p>0.05) when compared with that of the control group. Those which remain unchanged in each dose group were, body weight (BW) gain, feed intake, the hematology and coagulation indexes. Although, there were a few individual indicators that were abnormal, but the overall physiological appearance of the rats were normal. Conclusion: Results under this experiment revealed that most hematological and coagulation parameters of the SD rats in both male and female were normal, although the weight gain of female rats in high-dose group was significantly reduced than those of the male rats. Under this study, the use of mulberry leaf up to 2 g/kg BW did not result in abnormal phenomenon in the SD rats. These findings would offer useful information for further in vivo feeding trials in animals to extensively use of mulberry leaf to improve animal production, particularly in P.R. China.

A Methodology for Quality Control of Railroad Trackbed Fills Using Compressional Wave Velocities : I. Preliminary Investigation (압축파 속도를 이용한 철도 토공노반의 품질관리 방안 : I. 예비연구)

  • Park, Chul-Soo;Mok, Young-Jin;Choi, Chan-Yong;Lee, Tai-Hee
    • Journal of the Korean Geotechnical Society
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    • v.25 no.9
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    • pp.45-55
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    • 2009
  • The quality of railroad trackbed fills has been controlled by field measurements of density and bearing resistance of plate-load tests. The control measures are compatible with the design procedures whose design parameter is $k_{30}$ for both ordinary-speed railways and high-speed railways. However, one of fatal flaws of the design procedures is that there are no simple laboratory measurement procedures for the design parameters ($k_{30}$ or, $E_{v2}$ and $E_{v2}/E_{v1}$) in design stage. To overcome the defect, the compressional wave velocity was adopted as a control measure, in parallel with the advent of the new design procedure, and its measurement technique was proposed in the preliminary investigation. The key concept of the quality control procedure is that the target value for field compaction control is the compressional wave velocity determined at optimum moisture content using modified compaction test, and direct-arrival method is used for the field measurements during construction, which is simple and reliable enough for practice engineers to access. This direct-arrival method is well-suited for such a shallow and homogeneous fill lift in terms of applicability and cost effectiveness. The sensitivity of direct-arrival test results according to the compaction quality was demonstrated at a test site, and it was concluded that compressional wave velocity can be effectively used as quality control measure. The experimental background far the companion study (Park et al., 2009) was established through field and laboratory measurements of the compressional wave velocity.

Hydrogeological Performance Assessment for Underground Oil Storage Caverns (지하유류비축시설 수리안정성 평가방안)

  • 김천수;배대석;김경수;고용권;송승호
    • The Journal of Engineering Geology
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    • v.7 no.3
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    • pp.229-245
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    • 1997
  • There are Common aspects between the underground oil storage cavern and the radioactive waste disposal facility. Both facilities use appropriately the intrinsic natural berrier characteristics of the rock mass and additionally the engineered barrier system for the long term safety. The geological structures and their hydrogeological characteristics in a faactured rock mass act a major role in the safety and performance of the underground oil storage facility through the design, construction and the operation stages. Because the fracture system distributed in a fractured rock block is complicated owing to their own geometrical and hydrogeological attributes, the hydrogeological perforrmrnce of the facility would depend mainly upon the understandings of their characteristics. This study reviews the uncertainties and key issues which have to be considered to analyse the groundwater flow system in a fractured rock mass and proposes the techniques applicable to characterize the hydrogeological parameter.

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Study of Optimal Light Scattering Pattern Design for Flat Lighting Device using Glass Light Guide (유리도광체를 이용한 평판조명용 광확산패턴의 최적설계 연구)

  • Han, Jeong-Min;Kim, Won-Bae
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.66 no.4
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    • pp.242-246
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    • 2017
  • In this study, it was investigated about optical simulation in high brightness and high uniformity general lighting using glass light guide plate. And we adopt edge-light emission type light plate. Edge-light type lighting has been used LCD application, especially note PC or smart phone backlight unit. Because it had the good properties such as slim shape and light weight. We thought this type was suitable for general lighting application such as wall attached type or ceiling mount type. But many of edge-light type lighting had problems. It called slanted output light rays. That was main key parameter how could control the direction of output light rays. We investigated the solution of this problems, using ray tracing method, we recognized the major fact of the solution relied on the geometric structure of diffusing dot shape. We set the conditions of aspect ratio in diffusing dot shape such as 0.5 to 1. And, at first, we designed diffusing dots shape based on the results of optical simulation and made specimen. as above condition, and acquired good result in confirming dots shape such as the value of the output rays's peak angle was around 75 degrees. And good light distribution characteristics were measured by slated spectro-radiometer. It was shown that the effective ways of designing light distribution characteristics using optical simulation such as ray tracing linear method for making general lighting using glass light guide plate.