• 한국재료학회지
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• 제5권7호
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• pp.897-902
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• 1995

경북 감포지역에서 산출되는 천연 벤토나이트를 이용하여 제올라이트 A를 합성하기 위해 반응기질의 몰비, 반응온도, 반응시간 등에 따른 최적의 합성조건을 조사하였다. 실리카원은 40%-황산용액으로 처리한 천연 벤토나이트를 사용하였고, 알루미늄원은 NaA1O₂를 합성하여 사용하였다. 반응기질의 몰비는 SiO₂ : A1₂O₃ : NaO₂ : H₂O=2 : 1 : 1 : 25와 2 : 1 : 1 : 30이었고, 60℃에서 1시간 묵힘과정을 거친 후 90, 100, 120℃에서 1, 3, 5hr반응시켰다 제올라이트 A의 최적의 합성조건은 SiO₂: Al₂O₃ : Na₂O = H₂O=2 : 1 : 1 : 30이고, 90℃에서 3hr 반응시키는 경우였고, 이 조건에서 합성된 제올라이트의 열적 성질은 79.2℃에서 층간수가 증발하였고, 503.0℃에서 결정수가 탈리되었다. 수분의 감소량은 제올라이트 중량비의 5.9%이었다.

• 대한한방소아과학회지
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• 제34권3호
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• pp.1-17
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• 2020

Objectives The purpose of this study is to analyze clinical studies on effectiveness of herbal medicine in refractory nephrotic syndrome (RNS). Methods We searched the randomized controlled trials (RCTs) with herbal medicine treatment on RNS from the Pubmed, CNKI, OASIS, NDSL, J-stage, and CiNii. The demographic data, duration of illness, intervention, treatment period, outcome, adverse events, and composition of herbal medicine were analyzed for this study. Results 11 RCT studies were selected and analyzed. The children in the control group were given western medicine therapy, and the treatment group was given herbal medicine along with the same western medicine of the control group. The most commonly used herbal medicines were the prescriptions to treat 'Kidney Deficiency with Blood Stasis (腎虛兼瘀血)' which composed of 'Promoting blood circulation (化瘀)', 'Diuresis-inducing (利水)', or 'Heating Yang (溫陽)' medicine based on 'Replenishing Kidney or Spleen (補腎, 補脾)' medicine. In the treatment group, proteinuria and serum lipid was significantly decreased, serum albumin was significantly increased, and total effective rate was significantly higher than the control group. Hypercoagulation and relapse rate was also significantly reduced. Adverse events were significantly lower in the treatment group. Conclusions Herbal medicine treatment on pediatric RNS can be suggested as a new treatment for children who have less response to the conventional therapy. It can also supplement the limitations of the western medicine by reducing adverse events from the steroids and immuno-suppressive agents, and lower the relapse rate as well.

• Korean Journal of Acupuncture
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• 제33권1호
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• pp.12-17
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• 2016

목적 : 본 연구는 일본 의과대학에서의 전통의학의 교육 현황에 대한 개괄적 정보를 생성하기 위함이다. 방법 : 연구자들은 그 동안의 발표된 논문을 비롯한 일본 의과대학에서 웹사이트에 공지된 내용 및 각 의과대학의 행정부서와의 전자메일을 통해서 취득한 정보를 통하여 전통의학 교육에 대한 분석을 하였다. 결과 : 2001년 일본 문부성이 의과대학생의 전통의학에 대한 교육의 당위성을 고지한 이후에, 대부분의 일본의 의과대학에서는 전통의학의 과목을 신설하기 시작하였다. 본 연구에서 자세한 정보를 확보한 의과대학의 전통의학 교육에 대한 분석 결과, 약 90%의 일본 의과대학에서 정규과목으로서 전통의학 관련 교육을 실시하고 있었다. 교육내용은 대부분이 전통의학 개론에 대한 것으로, 61.9%가 4학년 학생들에게 실시되고 있으며, 평균 강의시간은 $16.2{\pm}8.8$ 시간이었다. 결과 : 본 연구의 결과는 향후 한국한의학의 국제화를 비롯한 대외적 경쟁력 확보 전략의 수립에 중요한 기초자료로 활용되길 기대한다.

• 한국재료학회지
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• 제5권8호
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• pp.1035-1039
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• 1995

경북 감포지역에서 산출되는 천연 벤토나이트를 이용하여 제올라이트를 합성하였으며 세제용 builder로서 가능성을 연구하였다. 최적의 합성조건은 기질의 몰비가 SiO$_2$/Al$_2$O$_3$=2, $Na_2$O$_3$/Al$_2$O$_3$=1, $H_2O$/A1$_2$O$_3$=30이고 9$0^{\circ}C$에서 3시간 반응시킬 경우였고, 이 조건에서는 A형 제올라이트가 합성되는 것을 XRD를 통하여 확인하였다. 최적 조건에서 합성된 제올라이트의 이온교환능을 측정하기 위하여 경도 40$^{\circ}$Dh의 CaCl$_2$용액과 3$0^{\circ}C$에서 IS분 접촉시킨 결과 264.9mg CaO/g-zeolite 정도로 우수한 값을 나타내었다. 이 시료의 백색도는 89%이었고, 평균 입자크기는 9.95$\mu\textrm{m}$이었다.

• Journal of Ginseng Research
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• 제44권2호
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• pp.238-246
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• 2020

Background: Dietary fat has been suggested to be the cause of various health issues. Obesity, hypertension, cardiovascular disease, diabetes, dyslipidemia, and kidney disease are known to be associated with a high-fat diet (HFD). Obesity and associated conditions, such as type 2 diabetes mellitus and nonalcoholic fatty liver disease (NAFLD), are currently a worldwide health problem. Few prospective pharmaceutical therapies that directly target NAFLD are available at present. A Traditional Chinese Medicine, ginseng-plus-Bai-Hu-Tang (GBHT), is widely used by diabetic patients to control glucose level or thirst. However, whether it has therapeutic effects on fat-induced hepatic steatosis and metabolic syndrome remains unclear. Methods: This study was conducted to examine the therapeutic effect of GBHT on fat-induced obesity, hepatic steatosis, and insulin resistance in mice. Results: GBHT protected mice against HFD-induced body weight gain, hyperlipidemia, and hyperglycemia compared with mice that were not treated. GBHT inhibited the expansion of adipose tissue and adipocyte hypertrophy. No ectopic fat deposition was found in the livers of HFD mice treated with GBHT. In addition, glucose intolerance and insulin sensitivity in HFD mice was also improved by GBHT. Conclusion: GBHT prevents changes in lipid and carbohydrate metabolism in a HFD mouse model. Our findings provide evidence for the traditional use of GBHT as therapy for the management of metabolic syndrome.

• 대한예방한의학회지
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• 제18권1호
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• pp.67-82
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• 2014

Objective : To find a treatment strategy, this study aimed to review and compare the clinical studies of Korea, China, and Japan on traditional medicine treatment for Behcet's disease. Method : Literature searches were performed on six databases in each country and English databases, such as OASIS, KoreanTK, CNKI, J-STAGE, PubMed, and Cochrane CENTRAL. In addition, using the limited keywords, the area was restricted to traditional medicine treatment, but the period was not limited. Studies were categorized according to the study design and we analyzed the difference of treatment among three countries. Results : One hundred and forty-one clinical studies met our inclusion criteria: 11 studies in Korea, 15 in Japan, 115 in China. Randomized controlled trials (RCT) have increased in China, however, no RCT was reported in Korea and Japan. The method of treatment was mainly traditional herbal medicine in all the three countries, but there were significant differences in the field of syndrome identification and prescription among countries. The studies in China made use of most various treatment modalities and reported the highest effectiveness. Conclusion : Traditional medicine treatment showed a considerable effect for improving various symptoms of Behcet's disease. However, more research for answering the safety and well-designed studies considering characteristics of Behcet's disease should be performed to evaluate the effectiveness of traditional medicine treatment objectively in the future.

• 대한한방소아과학회지
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• 제34권4호
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• pp.77-100
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• 2020

Objectives The purpose of this study is to investigate recent clinical studies on the effect of herbal medicine for pediatric tonsillitis in China, and to seek better methods to treat and study for pediatric tonsillitis in Republic of Korea. Methods We searched clinical studies from the China National Knowledge Infrastructure (CNKI) by search formula (SU='扁桃体炎'+'扁桃炎'+'扁桃腺炎'+'乳蛾'+'喉蛾'+'蚕蛾'+'石蛾'+'珠蛾'+'肉蛾'+'乳蛾風'+爛乳風'+'tonsillitis') and (SU='中樂'+'中医樂'+'本草'+'湯'+'丸'+'散'+'方'+'顆粒'+'膠囊'+'自擬'+'herb'+'herbal'+'decoction'+'remedy'+'Chinese medicine'+'Korean medicine'+'kampo'+'formula'+'herbal drug'+'Chinese drug'+'plant'+'Chinese prescription'+'traditional medicine'+'Medicine, East Asian Traditional'+'Herbal Medicine') in professional search from January 2016 to August 2020. We analyzed the literature focusing on the treatment methods and results. Results Among 1464 searched studies, 35 randomized controlled trials were selected and analyzed. In most studies, the effectiveness of oral administration of herbal medicine on pediatric tonsillitis was significant. Most commonly used herbs were Fructus Forsythiae (連翹), Radix Glycyrrhizae (甘草), Radix Scutellariae (黃芩), Herba Menthae (薄荷), Fructus Arctii (牛蒡子), Radix Scrophulariae (玄蔘), Radix Platycodi (桔梗), Flos Lonicerae (金銀花), Radix Isatidis (板藍根), Radix Bupleuri (柴胡), Fructus Gardeniae (梔子), Rhizoma Belamcandae (射干), Radix et Rhizoma Rhei (大黃), Gypsum Fibrosum (石膏). Conclusions By analyzing the improvement of indicators such as total effective rate, cured rate, symptom disappearance time and symptom score, we found that herbal medicine treatment can help improve pediatric tonsillitis. However, additional studies are needed to solidify these findings.

• 대한예방한의학회지
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• 제26권1호
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• pp.59-74
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• 2022

Objectives : Evidence supporting the cold-heat symptom and sasang constitution type, which are diagnostic items of traditional Korean medicine, is needed to manage sleep disturbances, which is a typical symptom of mibyeong (subhealth). This study examined the association between each cold-heat symptom and sleep disturbances according to each sasang constitution type. Methods : This research was a cross-sectional study of 5,793 subjects from the Korean Medicine Data Center (KDC) community cohort survey. The association between each cold-heat symptom and sleep disturbances was analyzed by logistic regression analysis adjusted for several demographic variables. Subgroup analysis was then performed for each type of sasang constitution. Results : The soeum and soyang types were 1.53 and 1.26 times more likely to have sleep disturbances than the taeum type. Sleep disturbances were associated with 'coldness of the abdomen', 'watery mouth' in the cold domain items, and 'body feverishness', 'flushed face and eye', 'thirst', and 'scanty dark urine' in the heat domain items. The soeum and soyang types were 1.55 and 1.39 times more likely to sleep less than five hours per night than the taeeum type. In addition, the associations of those showed a different pattern for each sasang constitution type. Conclusions : Sleep disturbances are associated with specific cold-heat symptoms, and the associated cold-heat symptoms differ according to the sasang constitution type. These results may help traditional medicine specialists select customized interventions for patients with sleep disturbances.

• 대한예방한의학회지
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• 제26권1호
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• pp.25-41
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• 2022

Background & Objectives : As the government of South Korea implemented policies to strengthen health insurance coverage, the health insurance benefit for raw herbal medicines has been promoted. This study investigated the current status of the herbal medicines coverage in the Japanese national health insurance to secure reference data for the design of herbal medicines coverage in South Korea. Methods : Literature review was conducted to collect and analyze the history and current situation on herbal medicines coverage in the Japanese health insurance system. To supplement the contents not presented in the documents, on-site interviews were conducted at the medical institutions and pharmacies that prescribed or prepared herbal medicines in Tokyo, Japan. The contents of the survey included the background and progress of the herbal medicines coverage, the status of herbal medicines use, the payment system, and the safety management of herbal medicines. Results : Since the introduction of health insurance in the 1960s, Japanese insurance system has covered herbal medicines, and so far, it has been maintained without any additional restrictions. When the raw herbal medicines are prescribed to outpatients, the preparation fee is set higher than that of other medicines, but overall payment regulations and systems for herbal medicine are generally the same as other medicines. Conclusions : The case of Japan can be a useful references and implications for national health insurance policy on herbal medicines in south Korea.

• 한방재활의학과학회지
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• 제34권1호
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• pp.97-108
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• 2024

Objectives The purpose of this study was to investigate the effectiveness and safety of herbal medicine treatment for Colles fractures through a systematic review and to provide evidence for applying herbal medicine treatment. Methods We searched for papers published from January 1, 2018 to October 18, 2023, in PubMed and China National Knowledge Infrastructure based on the keyword 'Colles fracture', 'Chinese traditional medicine', 'Chinese medicine', 'herbal medicine', 'drugs, chinese herbal', 'kampo', 'decoction', 'capsule', 'powder'. Results A total of 51 studies were searched at first research. Then the studies were screening according to the criteria, and 13 studies were finally selected. The oriental medical intervention analyzed in this study was an orally administered herbal medicine. Conclusions Studies have shown that herbal medicine has a significant effect on Colles fractures. However, all studies were assessed as having a high risk of bias. In the future, further well-designed studies are needed to demonstrate the effectiveness of herbal medicine for Colles fractures and reduce the risk of bias.