• Journal of radiological science and technology
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• v.16 no.2
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• pp.45-50
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• 1993

In this paper, the PAE of tube voltage of 93 diagnostic X-ray units those are using at the 19 general hospitals and 9 local clinics in the area of Sungnam, Inchun, and Seoul have been surveyed. The results are summarized as following. 1. PAE of tube Voltage 70, 100KV at the 56 (60%) X-ray units were ${\pm}7%$ below, at the 8 units (9%), were ${\pm}7%$ above, and those 29 X-ray units (31%) were ${\pm}7%$ below or above with the 70, 100KV tube Voltage in a unit. 2. PAE ${\pm}7%$ below were 68 X-ray units, at the low tube voltage (70KV), and 76 X-ray units at the high tube Voltage (100KV). 3. For six year-use abofe, used X-ray units were PAE ${\pm}7%$ above, and so, the longer used years the more X-ray units became declined in those performance. 4. PAE of tube Voltage were better efficiency at the large capacity 30 X-ray units than small capacity 10. 5. PAE ${\pm}7%$ abovein were only 8 units among 84 diagnostic X-ray units in the general hospitals.

• International Journal of Highway Engineering
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• v.16 no.2
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• pp.19-24
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• 2014

PURPOSES : The study objective was to evaluate rheology and physical properties of SBS-modified warm-mix asphalt (WMA) binders in comparison with hot-mix asphalt (HMA) binders. METHODS : Four different SBS polymers were used to prepare polymer-modified asphalt (PMA) binders, and three different warm-mix additives (WAD) were used to prepare a total of 12 WMA PMA binders. The kinematic viscosity was measured at 115, $135^{\circ}C$. The PG was determined using DSR and BBR. The pass/fail (P/F) temperatures for high and low PG grading were evaluated for HMA PMA and WMA PMA binders. RESULTS : PG 76-22 binders could be prepared by modifying the base binder (PG 64-22) using 4.5 wt% of SBS. The kinematic viscosity (KV) of SBS PMA was increased by 3 times higher than that of base asphalt. The SBS PMA with WAD showed 10% lower KV than that of the normal SBS PMA at $115^{\circ}C$ The high P/F temperatures showed almost no difference between HMA PMA and WMA PMA binders. The high P/F temperature showed very high correlations with KV ($R^2$ > 0.97). The result of SBS modification caused increase of low P/F temperature by $2.7^{\circ}C$ on average. CONCLUSIONS : Since the PMA with WAD showed 10% lower KV than normal (HMA) PMA at $115^{\circ}C$, reducing PMA mixture temperature down to a WMA level was possible in this study. The higher KV binders showed the higher P/F temperature. There was almost no change in high P/F temperature due to the use of WAD. The SBS PMA, showing an increased low P/F temperature, might show somewhat poorer performance at low-temperature, even though the lower PG grade was staying at the same level, i.e., $-22^{\circ}C$.

• The Korean Journal of Physiology and Pharmacology
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• v.16 no.5
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• pp.343-348
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• 2012

Blocking or regulating $K^+$ channels is important for investigating neuronal functions in mammalian brains, because voltage-dependent $K^+$ channels (Kv channels) play roles to regulate membrane excitabilities for synaptic and somatic processings in neurons. Although a number of toxins and chemicals are useful to change gating properties of Kv channels, specific effects of each toxin on a particular Kv subunit have not been sufficiently demonstrated in neurons yet. In this study, we tested electro-physiologically if heteropodatoxin2 ($HpTX_2$), known as one of Kv4-specific toxins, might be effective on various $K^+$ outward currents in CA1 neurons of organotypic hippocampal slices of rats. Using a nucleated-patch technique and a pre-pulse protocol in voltage-clamp mode, total $K^+$ outward currents recorded in the soma of CA1 neurons were separated into two components, transient and sustained currents. The extracellular application of $HpTX_2$ weakly but significantly reduced transient currents. However, when $HpTX_2$ was added to internal solution, the significant reduction of amplitudes were observed in sustained currents but not in transient currents. This indicates the non-specificity of $HpTX_2$ effects on Kv4 family. Compared with the effect of cytosolic 4-AP to block transient currents, it is possible that cytosolic $HpTX_2$ is pharmacologically specific to sustained currents in CA1 neurons. These results suggest that distinctive actions of $HpTX_2$ inside and outside of neurons are very efficient to selectively reduce specific $K^+$ outward currents.

• Clinical and Experimental Pediatrics
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• v.61 no.9
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• pp.271-278
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• 2018

Purpose: Abnormal potassium channels expression affects vessel function, including vascular tone and proliferation rate. Diverse potassium channels, including voltage-gated potassium (Kv) channels, are involved in pathological changes of pulmonary arterial hypertension (PAH). Since the role of the Kv1.7 channel in PAH has not been previously studied, we investigated whether Kv1.7 channel expression changes in the lung tissue of a monocrotaline (MCT)-induced PAH rat model and whether this change is influenced by the endothelin (ET)-1 and reactive oxygen species (ROS) pathways. Methods: Rats were separated into 2 groups: the control (C) group and the MCT (M) group (60 mg/kg MCT). A hemodynamic study was performed by catheterization into the external jugular vein to estimate the right ventricular pressure (RVP), and pathological changes in the lung tissue were investigated. Changes in protein and mRNA levels were confirmed by western blot and polymerase chain reaction analysis, respectively. Results: MCT caused increased RVP, medial wall thickening of the pulmonary arterioles, and increased expression level of ET-1, ET receptor A, and NADPH oxidase (NOX) 4 proteins. Decreased Kv1.7 channel expression was detected in the lung tissue. Inward-rectifier channel 6.1 expression in the lung tissue also increased. We confirmed that ET-1 increased NOX4 level and decreased glutathione peroxidase-1 level in pulmonary artery smooth muscle cells (PASMCs). ET-1 increased ROS level in PASMCs. Conclusion: Decreased Kv1.7 channel expression might be caused by the ET-1 and ROS pathways and contributes to MCT-induced PAH.

• BMB Reports
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• v.52 no.8
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• pp.526-531
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• 2019

The vertebrate body plan is accomplished by left-right asymmetric organ development and the heart is a representative asymmetric internal organ which jogs to the left-side. Kupffer's vesicle (KV) is a spherical left-right organizer during zebrafish embryogenesis and is derived from a cluster of dorsal forerunner cells (DFCs). Cadherin1 is required for collective migration of a DFC cluster and failure of DFC collective migration by Cadherin1 decrement causes KV malformation which results in defective heart laterality. Recently, loss of function mutation of A-kinase anchoring protein 12 (AKAP12) is reported as a high-risk gene in congenital heart disease patients. In this study, we demonstrated the role of $akap12{\beta}$ in asymmetric heart development. The $akap12{\beta}$, one of the akap12 isoforms, was expressed in DFCs which give rise to KV and $akap12{\beta}$-deficient zebrafish embryos showed defective heart laterality due to the fragmentation of DFC clusters which resulted in KV malformation. DFC-specific loss of $akap12{\beta}$ also led to defective heart laterality as a consequence of the failure of collective migration by cadherin1 reduction. Exogenous $akap12{\beta}$ mRNA not only restored the defective heart laterality but also increased cadherin1 expression in $akap12{\beta}$ morphant zebrafish embryos. Taken together, these findings provide the first experimental evidence that $akap12{\beta}$ regulates heart laterality via cadherin1.

• 전기의세계
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• v.28 no.2
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• pp.14-22
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• 1979

전력계통의 증대에 따라 변전소용 변압기도 대용량화되어 가고 있다. 변전소용 대용량 변압기의 경우 최대문제가 되는 것은 철도운송의 경우 운송한계에 있다. 일본의 철도는 협궤이기 때문에 운송능력이 작고 275KV 변압기의 경우 조립운송할 수 있는 한계용량은 종래 300MVA라고 되어 왔지만, 최근 기술의 진보와 신뢰성 향상 시책에 따라 450MVA까지도 철도운송을 하는 것이 가능케 되었다. 이와같은 사정때문에 당사는 이번에 중부 전력.북풍전변전소에 3상 60Hz, 275/15 4/31.5KV, 450/450/135MVA 변압기를 납품하였다. 본기는 초고압 변전소용으로는 일본에서 최대급의 것으로 여러가지의 특징을 가지고 있다. 그 주요점을 들면, (1) 철도에 의한 조립운송을 가능케 했다. 더우기 부하시 TAP 절환기를 본체 TANK에 조립해서 운통한다. (2) 일차 초고압 권선에는 선로단을 중앙에 배치한 HISERCAP 권선을 채용한다. (3) 당초 65Phon, 장래 55Phon의 저소음사양을 만족시키기 위해서 고효율의 송유풍냉식 저소음방열관을 사용했다. (4) 기기의 신뢰성을 높이기 위해 설계, 제조, 시험 검사 각면에 만전을 기했다. 그러나 그외에도 여러가지 연구가 추진되고 있으며 다음에 개요를 설명하고져 한다.

• Proceedings of the KIEE Conference
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• 1991.07a
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• pp.296-299
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• 1991

This paper reports the characteristics of sparkover discharge in flowing gas ranging from 0[m/s] to 30[m/s] under the needle-rod gap. The important results obtained from this paper are as followers. 1. The maximum sparkover voltage of flowing gas are about 3.1[kv](d=1[cm], 5.4[kv](d=2[cm]), 8.1[kv](d=3[cm]) higher than those of static gas 2. The empirical equation obtained from this experiment is [%]$\frac{Vs}{Re}=A\;log_{10}\;Re+B$ where A=$-7.79{\times}10$ B=$5.60{\times}10^2$ 3. The duration time of sparkover decreases with increasing the Reynolds number. 4. The discharge pattern can be controlled by adjustment of the Reynolds number

• Proceedings of the KIEE Conference
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• 1992.07b
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• pp.907-910
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• 1992

This paper deals with the mesurement and the analysis by means of EMTP simulation for the fast-rising switching surges. The fast-rising surges having up to 180ns of front time and 3.42 p.u of peak value were measured at the 154KV substations. The fast-rising surges are expected to cause electric breakdown because the penetrating surges to the transformers result in the higher stress in the winding end than the average stress along the winding.

• Journal of radiological science and technology
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• v.12 no.1
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• pp.17-23
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• 1989

We have developed of the exposure technique for the chest radiography to get different contrast in left and right lung fields simultaneously for the effective diagnosis, I.E., get high contrast to detect tuberculosis, dispersal shadow or exudative lesions of early tuberculosis and get better sharpness and wider latitude to detect growing lesions of lung cancer or lesions overlapped with bones. As a result, by using an additional filter Cu 1.2mm with BX-III screen side and sheet of yellow cellophane on BF-III screen side at the conventional KV ($80KV{\sim}100KV$) for the chest X-ray, we can get similar densities in both left and right lung fields and, thus, this method is considered to be very effective for the quality diagnosis for the routine chest radiography.

• Proceedings of the KIEE Conference
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• 1989.07a
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• pp.397-400
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• 1989

The interrupting capability of circuit breaker to have an effect on stability and reliability of the power system is largely determined by the fault current and prospective TRV (prospective transient recovery voltage). The prospective TRV, which is essentially a system function determined by the elements of the connected circuit, is not constant for a given system location but is affected by a number of variables. Therefore, the purpose of this study is to analyze the prospective TRV of KEPCO's 345KV transmission system by using EMTP (Electro-Magnetic Transients Program) and to compare the calculated values with the standard values in KSB 150 (1976)