• 제목/요약/키워드: KS A

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SPC관련 KS의 제개폐 및 KS A ISO 2859-3에 대한 고찰 (A Study on SPC-related KS and KS A ISO 2859-3)

  • 임재근;조병선;정수일
    • 산업경영시스템학회지
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    • 제28권2호
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    • pp.75-80
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    • 2005
  • As a result of globalization process and TBT agreement, KS is also being revised, reestablished and some are abolished according to international standards such as ISO, IEC, etc. Conventional KS sampling inspection standards contained many different procedures from ISO, but recently, to match with international standards, all the rest of the standards except KS A 3102, 3104, 3151 were abolished, and the even the ones being in use still are also scheduled and be revised. Especially, KS A 3101, KS A 3105, KS A 3109, which were used most frequently in Korea were abolished, and the KS A ISO $2859-0\~3$ which coincide with ISO standards were established 3 years ago, but the implementation rate is very slow. Starting next year the national examination for qualification process for the product quality related item will the started and the preparation is underway. This study will investigate the recent sampling inspection process of KS as well as SPC related KS overhaul problem and present the data to help workers in SPC related field. One of the main example will be on KS A ISO 2859-3 and will attempt to help those medium and small sized companies with examples.

A novel MLL2 gene mutation in a Korean patient with Kabuki syndrome

  • Kim, Soo Jin;Cho, Sung Yoon;Maeng, Se Hyun;Sohn, Young Bae;Kim, Su-Jin;Ki, Chang-Seok;Jin, Dong-Kyu
    • Clinical and Experimental Pediatrics
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    • 제56권8호
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    • pp.355-358
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    • 2013
  • Kabuki syndrome (KS) is a rare genetic disease with a distinctive dysmorphic face, intellectual disability, and multiple congenital abnormalities. KS is inherited in an autosomal dominant manner. As the primary cause of KS, MLL2 mutations have been identified in 56-76% of affected individuals who have been tested, suggesting that there may be additional genes associated with KS. Recently, a few KS individuals have been found to have de novo partial or complete deletions of an X chromosome gene, KDM6A, which encodes a histone demethylase that interacts with MLL2. Nevertheless, mutations in MLL2 are the major cause of KS. Although there are a few reports of KS patients in Korea, none of these had been confirmed by genetic analysis. Here, we report a case of a Korean patient with clinical features of KS. Using direct sequencing, we identified a frameshift heterozygous mutation for MLL2 : (c.5256_5257delGA;p.Lys1753Alafs$^*34$). Clinically, the patient presented with typical facial features, and diagnosis of KS was based on the diagnostic criteria. While KS is a rare disease, other malformations that overlap with those found in individuals with KS are common. Hence, the diagnosis of KS by mutational analysis can be a valuable method for patients with KS-like syndromes. Furthermore, in the near future, other genes could be identified in patients with KS without a detectable MLL2 mutation.

철도차량용 자동복합연결기의 KS 규격화에 관한 연구 (A Study on the KS Standardization of Automatic Complex Coupler for Railway Rolling Stock)

  • 이찬우;허현무
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2001년도 춘계학술대회 논문집
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    • pp.207-211
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    • 2001
  • Revision and establish of KS(Korean Standards) is currently actively discussed. It is just the time for a new world class standards under the new system with WTO(World Trade Organization). This paper is a part of "Researchs on the Standards in Railway rolling stock Field", as one of KS establish projects. The aim of this study is to define the requirements of railway rolling stock-designs, manufacture, and test methods for automatic complex coupler. In the former KS, there is no items matched with this purpose. Therefore a new part of KS is proposed.

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Development and Immunochemical Properties of Two Monoclonal Antibodies Specific to Human Chorionic Gonadotropin

  • Kim, You-Hee;Koh, Kwan-Sam
    • BMB Reports
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    • 제32권5호
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    • pp.474-479
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    • 1999
  • Using a hybridoma technique, spleen cells of Balb/c mice immunized with human chorionic gonadotropin (hCG) were fused with NS-1 mouse myeloma cells. Two hybrid cell lines, clones KS-8 and KS-19, secreting monoclonal antibodies to hCG, were isolated. KS-8 and KS-19 belong to the immunoglobulin $G_1$ subclass. With the aid of a double-antibody radioimmunoassay, it was established that the KS-8 monoclonal antibody recognizes an immunodeterminant of the $\beta$-subunit of hCG, whereas the KS-19 monoclonal antibody recognizes an epitope present on the $\alpha$-subunit of hCG. The KS-8 monoclonal antibody specifically reacts with human chorionic gonadotropin and shows cross-reactivity of less than 0.3% to other related human glycoprotein hormones. On the other hand, using a hemagglutination test based on antibody-induced agglutination of sheep red blood cells coated with hCG, It was shown that only the KS-19 monoclonal antibody was capable of inducing a positive reaction, although both monoclonal antibodies had similar binding capacity to the coated cells. The results from the dual screening procedures demonstrate that KS-8 and KS-19 monoclonal antibodies show high sensitivity in two different assays, and are hence useful for the qualitative and quantitative determination of hCG by both radioimmunoassay and hemagglutination inhibition tests.

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Kabuki syndrome: clinical and molecular characteristics

  • Cheon, Chong-Kun;Ko, Jung Min
    • Clinical and Experimental Pediatrics
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    • 제58권9호
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    • pp.317-324
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    • 2015
  • Kabuki syndrome (KS) is a rare syndrome characterized by multiple congenital anomalies and mental retardation. Other characteristics include a peculiar facial gestalt, short stature, skeletal and visceral abnormalities, cardiac anomalies, and immunological defects. Whole exome sequencing has uncovered the genetic basis of KS. Prior to 2013, there was no molecular genetic information about KS in Korean patients. More recently, direct Sanger sequencing and exome sequencing revealed KMT2D variants in 11 Korean patients and a KDM6A variant in one Korean patient. The high detection rate of KMT2D and KDM6A mutations (92.3%) is expected owing to the strict criteria used to establish a clinical diagnosis. Increased awareness and understanding of KS among clinicians is important for diagnosis and management of KS and for primary care of KS patients. Because mutation detection rates rely on the accuracy of the clinical diagnosis and the inclusion or exclusion of atypical cases, recognition of KS will facilitate the identification of novel mutations. A brief review of KS is provided, highlighting the clinical and genetic characteristics of patients with KS.

광안정제를 이용한 acetamiprid 액제의 살충효과 증진 (Enhancement of Insecticidal Activity of the Acetamiprid Soluble Concentrate using a Photostabilizer)

  • 김형민;이원기;김종관;석창수;이창혁;유용만;황인천
    • 농약과학회지
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    • 제10권3호
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    • pp.210-217
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    • 2006
  • 본 연구는 살충제인 acetamiprid 5% 액제(SL)의 광분해 문제를 해결하고자 화학적 및 생물학적 시험방법을 통하여 효과적인 보조제를 선발하고 선발된 보조제의 최적함량을 규명하고자 수행되었다. 시험에 사용된 보조제는 KS1과 KS2 2종이었으며, 화학적 평가를 위하여 광분해 시험을 실시하였고, 생물학적 평가를 위하여 고추를 대상으로 목화진딧물(Aphis gossypii)에 대한 살충 활성과 잎에서의 잔류량을 측정하였다. 보조제 첨가에 따라 acetamiprid 5% 액제의 광분해율은 감소되었으나 보조제의 종류에 따른 차이는 그다지 크지 않았다. 그러나 고추 목화진딧물에 대한 살충 활성과 옆에서의 잔류량 측정결과로는 보조제 KS1보다는 KS2가 우수한 생물활성과 높은 잔류량을 나타내어 KS2를 보조제로 선발하였다. 선발된 보조제 KS2를 0, 0.1, 0.5, 1% 함유한 함량별 시험에서는 함량이 가장 적은 시료에서 가장 낮은 광분해율을 보였으며, 고추 목화 진딧물에 대한 살충 활성과 잎에서의 잔류량 측정 결과에서도 보조제 KS2의 함량이 감소할수록 보다 우수한 생물활성과 높은 잔류량을 나타내는 것으로 측정되었다. 이에 따라 선발된 보조제 KS2의 최적 함량은 0.1%인 것으로 판단되었다. 이상의 결과는 적절한 보조제의 선발에 의하여 살충제의 광분해를 막을 수 있으며 이를 통하여 살충제의 활성을 증가시키고 살충제의 처리량을 줄일 수 있음을 보여주고 있다.

온라인 교육사이트의 서비스품질 측정을 위한 SERVPERF와 KS-SQI모형의 비교 (A Comparison of SERVPERF and KS-SQI for the On-line Education-website Service Quality Measurement)

  • 신미향
    • 디지털융복합연구
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    • 제9권5호
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    • pp.253-263
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    • 2011
  • 본 연구는 국내의 중 고교생이 많이 사용하는 온라인 교육사이트의 서비스품질을 측정하는데 있어서 SERVPERF모형과 KS-SQI모형 중에서 어느 것이 더 적합한지를 비교 분석하였다. AMOS7을 이용하여 분석한 결과, SERVPERF모형에서 서비스품질은 신뢰성, 유형성, 반응성, 공감성, 확산성으로 측정하는 모형으로 나타났다. 또한 KS-SQI모형의 서비스품질은 본원적 서비스와 예상외 서비스로 구성된 성과차원과 신뢰성, 친절성, 적극지원성, 접근용이성, 매체유형성으로 구성된 과정 차원으로 구성된 측정모형으로 나타났다. 두 모형간 비교에서는 KS-SQI가 경로분석에 대한 모형적합도 측면에서 더 우수한 것으로 나타났다.

바닥의 미끄럼 시험에 관한 한국산업표준(KS) 현황 및 적용 실태 (A Review of Current Status and Applications of Korean Industrial Standards (KS) on the Floor Slip Resistance Testing)

  • 백권혁;지석원;최수경
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2021년도 봄 학술논문 발표대회
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    • pp.19-20
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    • 2021
  • Although various laws and regulations have been put in place to prevent slips and falls, many accidents still occur. In this study, the root cause of slips and falls not decreasing were investigated. There are five types of slip resistance test methods in the Korean Industrial Standards (KS). Namely, KS F 2375:2016, KS F 2601:2020, KS F 2602:2016, KS L 1001:2020, and KS G 5821-1:2020 are listed. These test methods are cited in building certification standards (BF and G-SEED), construction specifications, and other documents that specify slip safety criteria. As a result of the investigation, a number of errors in KS regulations and legal text, errors in the manufacture and operation of slip testers, and errors in the use of measured values were found. These errors threaten the public life safety and disrupt industrial sites, and must be corrected immediately.

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안전경영 우수기업을 위한 KS A ISO 2859-2 및 2859-3에 대한 고찰 (- A Study on KS A ISO 2859-2 and 2859-3 for the Best Companies in Safety management -)

  • 임재근;조병선;정수일
    • 대한안전경영과학회지
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    • 제6권4호
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    • pp.83-97
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    • 2004
  • The growing importance of product quality is becoming more and more daily apparent as we enter the age of globalization around the world. And the product safety is getting more focus as well as product quality. As a result, many domestic companies are putting a lot of emphasis on safety measures and management activities and these companies' products are mainly superior to other companies' product. When we separate the product quality procedure into 3 steps, i.e. quality secure-quality confirm-quality guarantee, of course the 1st step is the most important, but also End step of product quality confirm process is important. And in mass production environment, sampling inspection is more desirable than the 100 % inspection procedure. As a part of globalization trend, KS system is also being revised and reestablished based on ISO, IEC, etc. which are based on international standard. Conventional KS sampling inspection standards were in many areas quite different from ISO sampling standards, only KS A 3102, 3104, 3151 are left and the rest become obsolete, and even the ones that are still around are planned to the gone step by step. It has been already 3 years since the new KS A ISO 2859-0-3 sampling inspection process has been established which the abolition of the popular KS A 3101, KS A 3105, KS A 3109, yet the implementation rate is very slow. This study will attempt to analyze the new KS A ISO 2859-2 and KS A ISO 2859-3, and try to understand the difference as that the new standard can be easily understood and used widely among companies, by using examples. Our attempt is to help implement with the companies with active safety involvement but the final result can be spread among other companies as well in the near future.