• Title/Summary/Keyword: KS A

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A Study on SPC-related KS and KS A ISO 2859-3 (SPC관련 KS의 제개폐 및 KS A ISO 2859-3에 대한 고찰)

  • Lim Jae-Geun;Cho Byung-Sun;Jung Soo-Il
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.28 no.2
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    • pp.75-80
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    • 2005
  • As a result of globalization process and TBT agreement, KS is also being revised, reestablished and some are abolished according to international standards such as ISO, IEC, etc. Conventional KS sampling inspection standards contained many different procedures from ISO, but recently, to match with international standards, all the rest of the standards except KS A 3102, 3104, 3151 were abolished, and the even the ones being in use still are also scheduled and be revised. Especially, KS A 3101, KS A 3105, KS A 3109, which were used most frequently in Korea were abolished, and the KS A ISO $2859-0\~3$ which coincide with ISO standards were established 3 years ago, but the implementation rate is very slow. Starting next year the national examination for qualification process for the product quality related item will the started and the preparation is underway. This study will investigate the recent sampling inspection process of KS as well as SPC related KS overhaul problem and present the data to help workers in SPC related field. One of the main example will be on KS A ISO 2859-3 and will attempt to help those medium and small sized companies with examples.

A novel MLL2 gene mutation in a Korean patient with Kabuki syndrome

  • Kim, Soo Jin;Cho, Sung Yoon;Maeng, Se Hyun;Sohn, Young Bae;Kim, Su-Jin;Ki, Chang-Seok;Jin, Dong-Kyu
    • Clinical and Experimental Pediatrics
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    • v.56 no.8
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    • pp.355-358
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    • 2013
  • Kabuki syndrome (KS) is a rare genetic disease with a distinctive dysmorphic face, intellectual disability, and multiple congenital abnormalities. KS is inherited in an autosomal dominant manner. As the primary cause of KS, MLL2 mutations have been identified in 56-76% of affected individuals who have been tested, suggesting that there may be additional genes associated with KS. Recently, a few KS individuals have been found to have de novo partial or complete deletions of an X chromosome gene, KDM6A, which encodes a histone demethylase that interacts with MLL2. Nevertheless, mutations in MLL2 are the major cause of KS. Although there are a few reports of KS patients in Korea, none of these had been confirmed by genetic analysis. Here, we report a case of a Korean patient with clinical features of KS. Using direct sequencing, we identified a frameshift heterozygous mutation for MLL2 : (c.5256_5257delGA;p.Lys1753Alafs$^*34$). Clinically, the patient presented with typical facial features, and diagnosis of KS was based on the diagnostic criteria. While KS is a rare disease, other malformations that overlap with those found in individuals with KS are common. Hence, the diagnosis of KS by mutational analysis can be a valuable method for patients with KS-like syndromes. Furthermore, in the near future, other genes could be identified in patients with KS without a detectable MLL2 mutation.

A Study on the KS Standardization of Automatic Complex Coupler for Railway Rolling Stock (철도차량용 자동복합연결기의 KS 규격화에 관한 연구)

  • 이찬우;허현무
    • Proceedings of the KSR Conference
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    • 2001.05a
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    • pp.207-211
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    • 2001
  • Revision and establish of KS(Korean Standards) is currently actively discussed. It is just the time for a new world class standards under the new system with WTO(World Trade Organization). This paper is a part of "Researchs on the Standards in Railway rolling stock Field", as one of KS establish projects. The aim of this study is to define the requirements of railway rolling stock-designs, manufacture, and test methods for automatic complex coupler. In the former KS, there is no items matched with this purpose. Therefore a new part of KS is proposed.

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Development and Immunochemical Properties of Two Monoclonal Antibodies Specific to Human Chorionic Gonadotropin

  • Kim, You-Hee;Koh, Kwan-Sam
    • BMB Reports
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    • v.32 no.5
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    • pp.474-479
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    • 1999
  • Using a hybridoma technique, spleen cells of Balb/c mice immunized with human chorionic gonadotropin (hCG) were fused with NS-1 mouse myeloma cells. Two hybrid cell lines, clones KS-8 and KS-19, secreting monoclonal antibodies to hCG, were isolated. KS-8 and KS-19 belong to the immunoglobulin $G_1$ subclass. With the aid of a double-antibody radioimmunoassay, it was established that the KS-8 monoclonal antibody recognizes an immunodeterminant of the $\beta$-subunit of hCG, whereas the KS-19 monoclonal antibody recognizes an epitope present on the $\alpha$-subunit of hCG. The KS-8 monoclonal antibody specifically reacts with human chorionic gonadotropin and shows cross-reactivity of less than 0.3% to other related human glycoprotein hormones. On the other hand, using a hemagglutination test based on antibody-induced agglutination of sheep red blood cells coated with hCG, It was shown that only the KS-19 monoclonal antibody was capable of inducing a positive reaction, although both monoclonal antibodies had similar binding capacity to the coated cells. The results from the dual screening procedures demonstrate that KS-8 and KS-19 monoclonal antibodies show high sensitivity in two different assays, and are hence useful for the qualitative and quantitative determination of hCG by both radioimmunoassay and hemagglutination inhibition tests.

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Kabuki syndrome: clinical and molecular characteristics

  • Cheon, Chong-Kun;Ko, Jung Min
    • Clinical and Experimental Pediatrics
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    • v.58 no.9
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    • pp.317-324
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    • 2015
  • Kabuki syndrome (KS) is a rare syndrome characterized by multiple congenital anomalies and mental retardation. Other characteristics include a peculiar facial gestalt, short stature, skeletal and visceral abnormalities, cardiac anomalies, and immunological defects. Whole exome sequencing has uncovered the genetic basis of KS. Prior to 2013, there was no molecular genetic information about KS in Korean patients. More recently, direct Sanger sequencing and exome sequencing revealed KMT2D variants in 11 Korean patients and a KDM6A variant in one Korean patient. The high detection rate of KMT2D and KDM6A mutations (92.3%) is expected owing to the strict criteria used to establish a clinical diagnosis. Increased awareness and understanding of KS among clinicians is important for diagnosis and management of KS and for primary care of KS patients. Because mutation detection rates rely on the accuracy of the clinical diagnosis and the inclusion or exclusion of atypical cases, recognition of KS will facilitate the identification of novel mutations. A brief review of KS is provided, highlighting the clinical and genetic characteristics of patients with KS.

Enhancement of Insecticidal Activity of the Acetamiprid Soluble Concentrate using a Photostabilizer (광안정제를 이용한 acetamiprid 액제의 살충효과 증진)

  • Kim, Hyeong-Min;Lee, Weon-Kee;Kim, Jong-Kwan;Seok, Chang-Su;Lee, Chang-Hyuk;Yu, Yong-Man;Hwang, In-Cheon
    • The Korean Journal of Pesticide Science
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    • v.10 no.3
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    • pp.210-217
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    • 2006
  • The study was carried out to select the effective adjuvant as a photostabilizer for acetamiprid 5% SL(soluble concentrate) and to find its optimum content by using chemical and biological methods. Adjuvants used for the study were KS1 and KS2. Photodegradation test, insecticidal efficacies and residual analysis for the study were investigated. Although photodegradation rate of acetamiprid SL was decreased by addition of KS1 and KS2, the difference between KS1 and KS2 was not significant. As KS2 showed better efficacies against the cotton aphid (Aphis gossypii) and higher amount of residue on pepper than KS1, KS2 was selected as a photostabilizer for acetamiprid SL. Acetamipid SL with KS2 showed lower photodegradation rate, better efficacies against the cotton aphid (Aphis gossypii) and higher amount of residue on pepper as content of KS2 in acetamiprid SL was decreased. Therefore, it was concluded that the optimum content of KS2 was 0.1%. These results have demonstrated that the selected adjuvant could be used to enhance insecticidal activity and reduce spay dose of insecticide by protecting its photodegradation.

A Comparison of SERVPERF and KS-SQI for the On-line Education-website Service Quality Measurement (온라인 교육사이트의 서비스품질 측정을 위한 SERVPERF와 KS-SQI모형의 비교)

  • Shin, Mi-Hyang
    • Journal of Digital Convergence
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    • v.9 no.5
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    • pp.253-263
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    • 2011
  • In this study of the domestic high school and middle school students to use the online education-website to measure the quality of service between SERVPERF model and the KS-SQI model fits which were analyzed further. Analysis using AMOS 7, SERVPERF for measuring quality of service reliability, responsiveness, assurance, empathy and tangibility, was a measurement model. KS-SQI for primary needs fulfillment, unexpected benefit were performance dimensions, reliability, individual empathy, positive assistance, accessibility and media tangibility, consist of process dimension was measured. In comparison of two models, the KS-SQI model on a path analysis showed better in terms of model fit indexes.

A Review of Current Status and Applications of Korean Industrial Standards (KS) on the Floor Slip Resistance Testing (바닥의 미끄럼 시험에 관한 한국산업표준(KS) 현황 및 적용 실태)

  • Baik, Kwon-Hyuk;Ji, Suk-Won;Choi, Soo-Kyung
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2021.05a
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    • pp.19-20
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    • 2021
  • Although various laws and regulations have been put in place to prevent slips and falls, many accidents still occur. In this study, the root cause of slips and falls not decreasing were investigated. There are five types of slip resistance test methods in the Korean Industrial Standards (KS). Namely, KS F 2375:2016, KS F 2601:2020, KS F 2602:2016, KS L 1001:2020, and KS G 5821-1:2020 are listed. These test methods are cited in building certification standards (BF and G-SEED), construction specifications, and other documents that specify slip safety criteria. As a result of the investigation, a number of errors in KS regulations and legal text, errors in the manufacture and operation of slip testers, and errors in the use of measured values were found. These errors threaten the public life safety and disrupt industrial sites, and must be corrected immediately.

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- A Study on KS A ISO 2859-2 and 2859-3 for the Best Companies in Safety management - (안전경영 우수기업을 위한 KS A ISO 2859-2 및 2859-3에 대한 고찰)

  • Lim Jae Geun;Cho Byung Sun;Jung Soo Il
    • Journal of the Korea Safety Management & Science
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    • v.6 no.4
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    • pp.83-97
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    • 2004
  • The growing importance of product quality is becoming more and more daily apparent as we enter the age of globalization around the world. And the product safety is getting more focus as well as product quality. As a result, many domestic companies are putting a lot of emphasis on safety measures and management activities and these companies' products are mainly superior to other companies' product. When we separate the product quality procedure into 3 steps, i.e. quality secure-quality confirm-quality guarantee, of course the 1st step is the most important, but also End step of product quality confirm process is important. And in mass production environment, sampling inspection is more desirable than the 100 % inspection procedure. As a part of globalization trend, KS system is also being revised and reestablished based on ISO, IEC, etc. which are based on international standard. Conventional KS sampling inspection standards were in many areas quite different from ISO sampling standards, only KS A 3102, 3104, 3151 are left and the rest become obsolete, and even the ones that are still around are planned to the gone step by step. It has been already 3 years since the new KS A ISO 2859-0-3 sampling inspection process has been established which the abolition of the popular KS A 3101, KS A 3105, KS A 3109, yet the implementation rate is very slow. This study will attempt to analyze the new KS A ISO 2859-2 and KS A ISO 2859-3, and try to understand the difference as that the new standard can be easily understood and used widely among companies, by using examples. Our attempt is to help implement with the companies with active safety involvement but the final result can be spread among other companies as well in the near future.