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Anti-atherosclerotic Effects of Ethanol Extract of Soy Leaves (Glycine max) Supplementation on Suppression of Atherogenic Lesion Formation in LDL Receptor-Deficient Mice (저밀도지단백질 수용체 결손 마우스에서 동맥병변 형성을 억제하는 콩잎 주정추출물의 항동맥경화 효과)

  • Han, Jong-Min;Han, Jang-Il;Baek, Seung-Hwa;Li, Hua;Park, Ji-Seon;Cho, Moon-Hee;Park, Ki-Hun;Lee, Woo-Song;Jeong, Tae-Sook
    • 한국약용작물학회:학술대회논문집
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    • 2008.11a
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    • pp.388-389
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    • 2008

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Prevention of Macrophage-Related Inflammatory Diseases by Allergina

  • Han, Sang-B.;Lee, Chang-W.;Park, Song-K.;Yoon, Won-K.;Moon, Jae-S.;Lee, Ki-H.;Kim, Hyung-C.;Kim, Hwan-M.
    • Archives of Pharmacal Research
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    • v.26 no.4
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    • pp.312-316
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    • 2003

  • The oriental herbal combination allergina has been shown to inhibit allergic inflammation. In the present study, we demonstrate that the oral administration of allergina markedly inhibits the progression of inflammatory diseases, such as graft-versus-host diseases (in the allogeneic bone marrow transplantation and the parent-into-F1 transplantation models), collagen-induced arthritis and sheep red blood cell-induced delayed type hypersensitivity. The immunosuppressive activity of allergina in vivo appears to be associated, at least in part, with the inhibition of tumor necrosis factor-a production. In conclusion, our results suggest that allergina could be useful as a immunosuppressive agent for the treatment of macrophage-related inflammatory disease.

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The effect of polysaccharide isolated from the root of Acanthopanax koreanum on B cell activation

  • Han, S-B;Ahn, H-J;Yoon, Y-D;Kim, Y-H;Lee, J-J;Moon, J-S;Lee, C-W;Lee, K-H;Park, S-K
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.11b
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    • pp.183-183
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    • 2002

  • Many polysaccharides isolated from plants have been shown to enhance various immune responses in vivo and in vitro. Here we demonstrate that polysaccharide isolated from the root of Acanthopanax koreanum (AK) has a unique mode of immunostimulation with regard to its cell-type specificity.(omitted)

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