• 제목/요약/키워드: KOGA

검색결과 56건 처리시간 0.025초

EFFECT OF GONADOTROPHINS ON FOLLICULAR STEROID HORMONE PRODUCTION IN HYPOPHYSECTOMISED HENS (Gallus domesticus)

  • Li, Z.D.;Koga, O.;Tanaka, K.;Fujihara, N.
    • Asian-Australasian Journal of Animal Sciences
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    • 제6권3호
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    • pp.411-416
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    • 1993
  • We assessed effects of ovine luteinizing hormone (oLH) and follicle-stimulating hormone (oFSH) on the granulose and theca layers from the four largest follicles, $F_1-F_4$ of hens which had been hypophysectomized 12 h before expected ovulation. Ovine LH (0.4 mg), oFSH (0.4 mg) or oLH in combination with oFSH (0.4 mg each) was injected intravenously 6 h after hypophysectomy. Progesterone, testosterone and $estradiol-17{\beta}$ levels of the granulose and theca layers which were removed 6 h after hormone injection, were measured by radioimmunoassay. Progesterone contents of $F_1-F_3$ granulosa layer at 12 h after hypophysectomy were much lower than those of control hens. This reduced progesterone level was restored partially by the injection of oLH alone for $F_1$, while no follicles responded to oFSH treatment. In contrast, the injection of oLH in combination with oFSH resulted in high progesterone content of the granulose layer from all four follicles. Progesterone content of the theca layer was negligible in all treatments. Simultaneous injection of oLH and oFSH also elevated $estradiol-17{\beta}$ level accumulating in the theca layer from all follicles, of which much higher concentrations of $estradiol-17{\beta}$ were observed when comparison were made to each of their corresponding controls. No appreciable change in testosterone contents of two layers was observed in the present experiments. These results suggest that oFSH augments function of oLH to stimulate the production of progesterone in the granulose layer and $estradiol-17{\beta}$ in the theca layer.

LNG 인수기지의 방류해수를 이용한 소수력발전 개발방안 (Small Hydraulic Power Generation using the Discharging Seawater from LNG Receiving Terminal)

  • 하종만;채정민;손화승
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2010년도 춘계학술대회 초록집
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    • pp.192.2-192.2
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    • 2010
  • 일반적 의미의 소수력발전은 계곡이나 저낙차의 하천에서 시도되었으나, 한국의 지형과 강수패턴등은 소수력발전을 활성화하기에 어려운 점들이 있었다. 이에 최근에는 정수장, 하수처리장등과 같은 인공구조물에 소수력발전을 설치 운영하는 방향으로 가고 있으며, 특히 화력발전소 냉각공정에 사용되는 해수를 이용한 소수력발전이 크게 성공하였고 확대설치 되어가고 있다. 해안에 위치하는 LNG인수기지에서는 LNG의 기화에 해수를 열원으로 사용하며, 기화공정에서 열교환 후 바다에 배출된다. 이 때 기화해수와 공기와의 접촉으로 생성된 거품은 해양미생물과의 복합작용으로 쉽게 깨어지지 않고 바다로 떠내려가게 된다. 이러한 거품은 시각적 거부감으로 인하여 인근어민들의 불편함을 야기하고 있으며, 또한 배출해수와 일반해수와의 온도차로 인한 인근 어장이나 양식장의 어획고에 미칠 수 있는 부작용의 가능성에 대한 우려는 더욱 방류해수의 적절한 처리를 필요로 하고 있다. 이러한 방류해수의 거품생성을 해결하는 데 있어 근본적인 해결방법은 심층배수법인데, 심층배수 구조물에 발전수차를 추가 설치만 하면 수력발전이 가능하다. 방류해수의 거품관련 환경문제를 해결하면서 동시에 청정전력을 생산할 수 있는 해양소수력발전에 대하여 KOGAS에서는 LNG 인수기지에의 적용가능성을 분석하고 있으며, 방류해수의 낙차와 조수간만의 차를 이용하는 해양소수력발전을 LNG 인수기지에의 적용하는 것으로는 세계최초의 시도이다. 주변지형에 따른 입지여건을 분석하고, 해수계통분석, 소수력발전방법, 수차종류, 수차용량, 수차개수, pond의 크기등을 결정하고, 수리해석 및 경제성분석을 수행할 것이며 소수력발전의 타당성여부에 대한 가늠을 잡고자 한다.

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Thermoregulatory Responses of Swamp Buffaloes and Friesian Cows to Diurnal Changes in Temperature

  • Koga, A.;Kurata, K.;Furukawa, R.;Nakajima, M.;Kanai, Y.;Chikamune, T.
    • Asian-Australasian Journal of Animal Sciences
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    • 제12권8호
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    • pp.1273-1276
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    • 1999
  • Several reports have indicated that a rectal temperature of buffaloes is easily influenced by their surroundings. To clarify an effect of changing environmental temperature on thermoregulatory responses of buffaloes, an environment with diurnal temperature changes of $25^{\circ}C$ to $35^{\circ}C$ was created using an artificial climate laboratory. Three swamp buffaloes and three Friesian cows were exposed to three different experimental periods as follows: Period 1 (constant temperature of $30^{\circ}C$, Period 2 (diurnally changing temperature) and Period 3 (diurnally changing temperature and fasting). Heat production, rectal temperature, respiration rate, heart rate and respiration volume were measured during each period. Rectal temperature of the buffaloes fluctuated diurnally with the changing temperature (Periods 2 and 3), but remained constant in cows. Mean heat production was significantly lower in buffaloes than in cows in Period 2 and 3. However, the maximum rectal temperature and the increment of heat production were not always lower in buffaloes than in cows during Period 2. These results show that a rectal temperature and heat production in buffaloes are markedly influenced by the diurnal changes in temperature. Compared with Bos Taurus cows, the differences may be attributed to the physiological features of buffaloes including a high heat conductivity of their bodies and an lower heat production.

Internal Changes of Blood Compartment and Heat Distribution in Swamp Buffaloes under Hot Conditions : Comparative Study of Thermo-Regulation in Buffaloes and Friesian Cows

  • Koga, A.;Kurata, K.;Ohata, K.;Nakajima, M.;Hirose, H.;Furukawa, R.;Kanai, Y.;Chikamune, T.
    • Asian-Australasian Journal of Animal Sciences
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    • 제12권6호
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    • pp.886-890
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    • 1999
  • From previous studies, there is a strong possibility in buffaloes that the marked increase in blood volume (BV) under hot conditions contributes to heat transportation from the rectum to the skin. The present study was done to clarify changes with environmental temperature on water-shift between blood and extracellular fluid (ECF), heat distribution between the rectum and the skin, and blood flow rates (BFR) at the hind legs (reflecting the skin surface). Four buffaloes and four Friesian cows were successively exposed to three different temperatures of $20^{\circ}C$, $30^{\circ}C$ and $35^{\circ}C$. BV and ECF volume were measured with Evans' blue and sodium-thiocyanate dilution methods, respectively. Rectal and subcutaneous (as the skin) temperatures were measured by copper-constantan thermocouples. BFR were measured by a supersonic blood flow meter. With an increase in environmental temperature, skin temperature in buffaloes increased significantly than cows, but rectal temperature was not significantly different between two species. BV, especially plasma compartment, increased significantly in only buffaloes, while ECF volume did not change in both species. BFR increased significantly in buffaloes, but not in cows. From these results, the increased of BV may be caused by water flowing from ECF compartment. The water-shift may induce the increase of BFR and skin temperature. It is suggested in the present study that internal changes of blood compartment in buffaloes contribute to transfer of heat to the skin surface.

EFFECTS OF PREINCUBATION AND INSEMINATION TIMES OF SPERMATOZOA ON THE DEVELOPMENT OF BOVINE OOCYTES FERTILIZED IN VITRO

  • Tsuzuki, Y.;Ino, K.;Kimura, S.;Tanaka, N.M.;Fujihara, N.;Koga, O.
    • Asian-Australasian Journal of Animal Sciences
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    • 제4권2호
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    • pp.151-156
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    • 1991
  • Bovine in vitro fertilization experiment was carried out using ovary-derived follicular oocytes and frozen-thawed spermatozoa to determine the optimal preincubation time of spermatozoa and the insemination time for successful in vitro fertilization rate. The possibility of parthenogenetic cell division of unfertilized oocytes during culture without spermatozoa was also examined. There was no significant (p>0.05) difference in percent ratio of embryos developed to blastocyst stage between 0 and 3 h preincubation times of spermatozoa, showing a tendency to have higher percentage for 0 h of preincubation time. The 6 h insemination time seemed to be better for producing higher percentage of ova cleavage compared with those of 1 and 3 h treatments. Approximately 10% of unfertilized oocytes divided into 2 to 4-cell stage, and some of them cleaved to 5 up to 8-cells. The results obtained from this study suggested that 0 h of sperm preincubation time and 6 h of insemination time would be suitable for producing better in vitro fertilization rate of bovine oocytes. It is also likely that unfertilized bovine oocytes probably cleave to some cell stages with irregular divisions of the cells. On the one hand, considerable variation was also found in spermatozoa function among individual bulls.

Biomechanical considerations for uprighting impacted mandibular molars

  • Morita, Yukiko;Koga, Yoshiyuki;Nguyen, Tuan Anh;Yoshida, Noriaki
    • 대한치과교정학회지
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    • 제50권4호
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    • pp.268-277
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    • 2020
  • This case report demonstrates two different uprighting mechanics separately applied to mesially tipped mandibular first and second molars. The biomechanical considerations for application of these mechanisms are also discussed. For repositioning of the first molar, which was severely tipped and deeply impacted, a novel cantilever mechanics was used. The molar tube was bonded in the buccolingual direction to facilitate insertion of a cantilever from the buccal side. By twisting the distal end of the cantilever, sufficient uprighting moment was generated. The mesial end of the cantilever was hooked over the miniscrew placed between the canine and first premolar, which could prevent exertion of an intrusive force to the anterior portion of the dentition as a side effect. For repositioning of the second molar, an uprighting mechanics using a compression force with two step bends incorporated into a nickel-titanium archwire was employed. This generated an uprighting moment as well as a distal force acting on the tipped second molar to regain the lost space for the first molar and bring it into its normal position. This epoch-making uprighting mechanics could also minimize the extrusion of the molar, thereby preventing occlusal interference by increasing interocclusal clearance between the inferiorly placed two step bends and the antagonist tooth. Consequently, the two step bends could help prevent occlusal interference. After 2 years and 11 months of active treatment, a desirable Class I occlusion was successfully achieved without permanent tooth extraction.

외재적 변수를 이용한 딥러닝 예측 기반의 도시가스 인수량 예측 (Deep Learning Forecast model for City-Gas Acceptance Using Extranoues variable)

  • 김지현;김지은;박상준;박운학
    • 한국가스학회지
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    • 제23권5호
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    • pp.52-58
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    • 2019
  • 본 연구에서는 국내 도시가스 인수량에 대한 예측 모델을 개발하였다. 국내의 도시가스 회사는 KOGAS에 차년도 수요를 예측하여 보고해야 하므로 도시가스 인수량 예측은 도시가스 회사에 중요한 사안이다. 도시가스 사용량에 영향을 미치는 요인은 용도구분에 따라 다소 상이하나, 인수량 데이터는 용도별 구분이 어렵기 때문에 특정 용도에 관계없이 영향을 주는 요인으로 외기온도를 고려하여 모델개발을 실시하였다.실험 및 검증은 JB주식회사의 2008년부터 2018년까지 총 11년 치 도시가스 인수량 데이터를 사용하였으며, 전통적인 시계열 분석 중 하나인 ARIMA(Auto-Regressive Integrated Moving Average)와 딥러닝 기법인 LSTM(Long Short-Term Memory)을 이용하여 각각 예측 모델을 구축하고 두 방법의 단점을 최소화하기 위하여 다양한 앙상블(Ensemble) 기법을 사용하였다. 본 연구에서 제안한 일별 예측의 오차율 절댓값 평균은 Ensemble LSTM 기준 0.48%, 월별 예측의 오차율 절댓값 평균은 2.46%, 1년 예측의 오차율 절댓값 평균은 5.24%임을 확인하였다.

Meta-Analysis of Limited Thymectomy versus Total Thymectomy for Masaoka Stage I and II Thymoma

  • Pulle, Mohan Venkatesh;Asaf, Belal Bin;Puri, Harsh Vardhan;Bishnoi, Sukhram;Kumar, Arvind
    • Journal of Chest Surgery
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    • 제54권2호
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    • pp.127-136
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    • 2021
  • Background: This meta-analysis aimed to evaluate the incidence of tumor recurrence, postoperative myasthenia gravis, postoperative complications, and overall survival after limited versus total thymectomy for Masaoka stage I and II thymoma. Methods: A systematic search of the literature was conducted using the PubMed, Embase, MEDLINE, and Cochrane databases to identify relevant studies that compared limited and total thymectomy in Masaoka stage I-II patients. The quality of the included observational studies was assessed using the Newcastle-Ottawa Scale. The results of the meta-analysis were expressed as log-transformed odds ratios (log ORs), with 95% confidence intervals (CIs). Results: Seven observational studies with a total of 2,310 patients were included in the meta-analysis. There was an overall non-significant difference in favor of total thymectomy in terms of tumor recurrence (pooled log OR, 0.40; 95% CI, -0.07 to 0.87; p=0.10; I2=0%) and postoperative myasthenia gravis (pooled log OR, 0.12; 95% CI, -1.08 to 1.32; p=0.85; I2=22.6%). However, an overall non-significant difference was found in favor of limited thymectomy with respect to postoperative complications (pooled log OR, -0.21; 95% CI, -1.08 to 0.66; p=0.64; I2=36.1%) and overall survival (pooled log OR, -0.01; 95% CI, -0.68 to 0.66; p=0.98; I2=47.8%). Conclusion: Based on the results of this systematic review and meta-analysis, limited thymectomy as a treatment for stage I and II thymoma shows similar oncologic outcomes to total thymectomy.

공기업의 ERP시스템 구축 전략에 관한 연구: KOGAS 사례를 중심으로 (A study on ERP implementation strategy in the public enterprise: lessons from KOGAS)

  • 임성철;김기주;황재훈
    • 한국산업정보학회논문지
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    • 제14권5호
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    • pp.257-270
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    • 2009
  • 급변하는 환경변화에 신속하고 능동적으로 대처하고 경영관리의 효율성을 제고시키기 위한 중요한 요소로 ERP(Enterprise Resource Planning: 전사적 자원관리)는 전략적 차원에서 경쟁력 강화 방안으로 널리 구축되어 왔다. 본 연구는 공기업의 구축에서의 핵심성공요인들을 도출하기 위해 국내의 대표적인 공기업, KOGAS의 ERP시스템 구축 사례를 대상으로 실증 분석을 수행하였으며, 분석결과는 다음과 같다. 첫째, 시스템 관리가 잘 되고 기관장의 의지가 높을 수록 비용 및 시간 감소 성과에 긍정적인 영향을 미치는 것으로 나타났으며, 둘째, 시스템 관리가 잘 되고 사용자의 참여 수준이 높으며 기관장의 의지가 높을수록 경영과 정보환경 개선 성과에 긍정적인 영향을 미치는 것으로 나타났다.

Efficacy of endoscopy under general anesthesia for the detection of synchronous lesions in oro-hypopharyngeal cancer

  • Yoichiro Ono;Kenshi Yao;Yasuhiro Takaki;Satoshi Ishikawa;Kentaro Imamura;Akihiro Koga;Kensei Ohtsu;Takao Kanemitsu;Masaki Miyaoka;Takashi Hisabe;Toshiharu Ueki;Atsuko Ota;Hiroshi Tanabe;Seiji Haraoka;Satoshi Nimura;Akinori Iwashita;Susumu Sato;Rumie Wakasaki
    • Clinical Endoscopy
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    • 제56권3호
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    • pp.315-324
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    • 2023
  • Background/Aims: Image-enhanced endoscopy can detect superficial oro-hypopharyngeal squamous cell carcinoma; however, reliable endoscopy of the pharyngeal region is challenging. Endoscopy under general anesthesia during transoral surgery occasionally reveals multiple synchronous lesions that remained undetected on preoperative endoscopy. Therefore, we aimed to determine the lesion detection capability of endoscopy under general anesthesia for superficial oro-hypopharyngeal squamous cell carcinoma. Methods: This retrospective study included 63 patients who underwent transoral surgery for superficial oropharyngeal squamous cell carcinoma between April 2005 and December 2020. The primary endpoint was to compare the lesion detection capabilities of preoperative endoscopy and endoscopy under general anesthesia. Other endpoints included the comparison of clinicopathological findings between lesions detected using preoperative endoscopy and those newly detected using endoscopy under general anesthesia. Results: Fifty-eight patients (85 lesions) were analyzed. The mean number of lesions per patient detected was 1.17 for preoperative endoscopy and 1.47 for endoscopy under general anesthesia. Endoscopy under general anesthesia helped detect more lesions than preoperative endoscopy did (p<0.001). The lesions that were newly detected on endoscopy under general anesthesia were small and characterized by few changes in color and surface ruggedness. Conclusions: Endoscopy under general anesthesia for superficial squamous cell carcinoma is helpful for detecting multiple synchronous lesions.