• 한국방재안전학회논문집
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• 제14권1호
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• pp.23-40
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• 2021

세계적인 코로나19 대유행의 시대에, 현재 치료제·백신이 개발, 시판 중인 단계에서 병원내 교차감염의 위험성이 있는 상황이므로, 개인적으로는 후천적인 면역력을 제고하고 사회환경적으로 구리이온의 성능에 의한 생활방역체제를 일반화해야 한다. 감염확산방지를 위해 동서고금의 연구개발사례를 근거로 항균동 필름의 필요성 및 항바이러스 성능실험을 통해 효능성을 분석했다. 한국건설생활환경시험연구원(KCL)에서 항균성능인증 및 "국가승인 성능인증기관"에서 항바이러스 시험성적 인증을 받게 되었다. 당시 질병관리본부의 허가를 받은 실험재료인 NCCP 43326 Human corona virus(BetaCoV/Korea/KCDC03/2020)을 분양받아 생물안전기준에 맞게 생체외 실험실에서 In Vitro시험 결과, 항바이러스 성능시험에서 감염된 세포의 활성제거율이 만족할만한 결과를 도출하고 성능을 인증받게 되었다. 항후 코로나19 바이러스 확산방지대책으로 항바이러스 동필름이 시공된 유리창 공간내에서의 실험군과 항균동필름이 없는 동일조건의 대조군을 비교하는 질(質)적인 임상실험연구가 추가 필요하다.

• 한국지구과학회지
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• 제39권1호
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• pp.67-88
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• 2018

The important PH (paleontological heritages) with scientific, educational and esthetic values designated as natural monuments and protected by legislations of South and North Koreas are herein compared for the first time. On the basis of data (Jan. 2017) provided by the Cultural Heritage Administration of (South) Korea, a total of 457 natural monuments was designated. Of these, geological heritages are 80 in number, which includes 24 (30%) PH. Data (Dec. 2005) of North Korea show that a total of 474 natural monuments was designated. Among these, geological and geographical ones are 154 in number, which includes 22 (14%) PH. Differences between PH of South and North Koreas are regarded to be directly related with geological difference in distribution of the fossil-bearing strata between South and North Koreas. PH of Silurian corals, Devonian plants, Jurassic fishes, Cretaceous dinosaur tracks, birds (so called Korean Archaeopteryx) and pterosaurs, and Pleistocene paleoanthropological fossils appear to be scientifically significant. Together with these North Korean PH, scientific, esthetic, conservational, educational, and economical values of important PH including KCDC (Korean Cretaceous Dinosaur Coast), Jigunsan Shale, and Geumgwangdong Shale of South Korea should be evaluated as potential future candidates for international heritages.

• 대한치과의사협회지
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• 제58권10호
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• pp.615-626
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• 2020

The outbreak of COVID-19, caused by SARS-CoV-2 infection, has spread worldwide and resulted in a pandemic for health systems. The disease is transmitted via respiration as droplets or aerosol. Due to the nature of dental treatment, aerosols, including body fluid, blood, and saliva, are frequently produced in dental hospitals. The present study investigated the potential risk of nosocomial infection of COVID-19 in dental hospitals to provide recommendations in clinical situations. The Seoul National University Dental Hospital in Korea established a countermeasure to cope with the clinical situation based on The Guidelines of Korean Centers for Disease Control & Prevention (KCDC) for dental practitioners and the available literature. Notably, numerous considerations for patient reservation and schedule management are required for space separation in the hospital, including infection control. Experiences in dental hospitals in Korea would be referable for other dental hospitals facing this infectious respiratory disease.

• 대한지역사회영양학회지
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• 제11권1호
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• pp.98-107
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• 2006

This study was performed to test food preferences of the Korean elderly for Korean elderly menu development. The elderly subjects preferred steamed rice cooked with 1.2 times water than that with 1.5 times water (p < 0.001) , whole rice grain gruel than the gruel with ground grain (p < 0.05) . Green tea powder gruels developed as a snack, there were no significant differences in the preference of the elderly between gruel with different contents of green tea powder (2, 3, $4\%$). The preferences of the salt concentration of the soup were tested by using soybean sprout soup and soybean paste soup. The elderly preferred 0.7 - $0.8\%$ salted bean sprout soup and $7\%$ soybean paste soup. The elderly preferred Kimchi cut in widths of 1 - 2 cm than that in 0.5 cm. The elderly preferred sweeter grape jam ($67\%$ vs. $50\%$ or $37\%$ sugar content) and were not concerned about chewing seeds. This result could be useful to develop menus for the elderly. (Korean J Community Nutrition 11 (1): 98$\sim$107, 2006)

• Genomics & Informatics
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• 제5권4호
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• pp.152-160
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• 2007

Most common diseases are caused by multiple genetic and environmental factors. Among the genetic factors, single nucleotide polymorphisms (SNPs) are common DNA sequence variations in individuals and can serve as important genetic markers. Recently, investigations of gene-based and whole genome-based SNPs have been applied to association studies for marker discovery. However, SNPs are so population-specific that the association needs to be verified. Fifty-five genes and 384 SNPs were selected based on association with disease. Genotypes of 337 SNPs in candidate genes were determined using Illumina Sentrix Array Matrix (SAM) chips by an allele-specific extension method in 364 unrelated Korean individuals. Allelic frequencies of SNPs were compared with those of other populations obtained from the International HapMap database. Minor allele frequencies, linkage disequilibrium blocks, tagSNPs, and haplotypes of functional candidate SNPs in 55 genetic disease-associated genes were provided. Our data may provide useful information for the selection of genetic markers for gene-based genetic disease-association studies of the Korean population.

• International Journal of Aeronautical and Space Sciences
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• 제1권1호
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• pp.13-20
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• 2000

The applications of CFD in the design process of a transonic civil transport at Korea Aerospace Research Institute (KARI) are outlined. Three Navier-Stokes solvers, developed at KARI with different grid approaches, are used to predict the aerodynamic coefficients and solve the flowfield of various configurations. Multi-block, Chimera, and unstructured grids are the approaches implemented. The accuracy of the codes is verified for the transonic flow about RAE wing/fuselage configuration. The multi-block code is used to provide the detailed data on the flowfield around a wall interference model with different test section sizes which will be used in establishing the wall interference correction method. The subsonic and transonic flowfields about K100-04A, one of the configurations of a 100-seater transport developed by KARI and Korea Commercial Aircraft Development Consortium (KCDC), are computed to predict the aerodynamic coefficients. The results for the subsonic flow are compared with those of wind tunnel test, and the agreement is found to be excellent. The interference effect of nacelle installation on the wing of K100-04A is also investigated using the unstructured grid method, and about 10% reduction in wing lift is observed. The accuracy of the three developed codes is verified, and they are used as an efficient tool in the design process of a transonic transport.

• 지역사회간호학회지
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• 제23권1호
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• pp.31-39
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• 2012

Purpose: The purpose of this paper was to compare community health status by region and to investigate related factors using community health and social indicators. Methods: Data were collected from statistics of local districts that were provided by KNSO and KCDC. ANOVA and correlation were analyzed using PASW 18.0. Results: The standardized cancer mortality rate was higher in metropolitan areas than in other areas. On the contrary, the mortality of respiratory disease, traffic accident, and suicide were higher in rural areas. Small cities and county districts showed higher prevalence in obesity prevalence than metropolitan areas. Metropolitan areas presented higher prevalence in alcohol drinking during the previous month, perceived stress, and seat belt use. The age-adjusted standardized mortality rate was correlated with higher prevalence of smoking, obesity, percentage of the elderly, number of beds, number of social welfare facilities, number of registered cars, lower percentage of financial independence, number of doctors, and percentage of water supply service & sewage. Conclusion: Since significant differences in mortality rate and prevalence of health risk behaviors exist between regional areas and the mortality rate was correlated with other social indicators and health indicators, health policies and social policies considering these differences should be develop and implemented to the communities.

• Genomics & Informatics
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• 제5권2호
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• pp.61-67
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• 2007

The allele frequencies of markers as well as linkage disequilibrium (LD) can be changed in cases due to the LD between markers and the disease allele, exhibiting spurious associations of markers. To identify the true association, classical statistical tests for dealing with confounders have been applied to draw a conclusion as to whether the association of variants comes from LD with the known disease allele. However, a more direct test considering LD using estimated haplotype frequencies may be more efficient. The null hypothesis is that the different allele frequencies of a variant between cases and controls come solely from the increased disease allele frequency and the LD relationship with the disease allele. The haplotype frequencies of controls are estimated using the expectation maximization (EM) algorithm from the genotype data. The estimated frequencies are applied to calculate the expected haplotype frequencies in cases corresponding to the increase or decrease of the causative or protective alleles. The suggested method was applied to previously published data, and several APOE variants showed association with Alzheimer's disease independent from the APOE ${\varepsilon}4$ variant, rs429358, regardless of LD showing significant simulated p-values. The test results support the possibility that there may be more than one common disease variant in a locus.

• 보건교육건강증진학회지
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• 제29권5호
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• pp.115-123
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• 2012

Objectives: Students' life changes substantially as grade increases. It implies that risk factors that trigger students' smoking may not be consistent across grades. Most previous studies on student smoking have considered grade simply a control variable. This study examines which and to what extent risk factors are differently associated with smoking initiation according to grade level among high school students in Korea. Methods: Data from the Korean Youth Risk Behavior Web-based Survey (KYRBWS) conducted by the Korea Centers for Disease Control and Prevention (KCDC) in 2007 and 2008 were analyzed in this study. Results: Among boys, school location, school type and pocket money etc. significantly influence smoking initiation in the first grade than in any other grades, but the strength of the association decreased as grade increases except academic performance. Among girls, most independent variables were associated with smoking initiation in the second grade except school location, pocket money per week and academic performance. Conclusions: Our results suggested that the variables related smoking initiation in Korean high school students were notably different by grade and gender. These findings can serve as the basis of policy recommendations with regard to school efforts to prevent student smoking.

• 보건의료산업학회지
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• 제7권4호
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• pp.221-232
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• 2013

This study aims to analyze the effect of hypertense, diabetic patients, managerial characteristics on their depression and suicidal thinking. Thus, this study selected 6,217 adults over the age of 19 from the 5th first-year data of Korean National Health and Nutrition Examination Survey conducted by KCDC(Korea Centers for Disease Control and Prevention) in 2010. As factors having effect on their suicidal thinking, unmarried patients(p=.000), middle school(p=.045), high school(p=.015), college and higher(p=.018), medicare(p=.045), hypertense(p=.042), exercise walking irregularly(p=.021), sense of depression(p=.035) showed a higher rate of suicidal thinking which were found to be statistically significant variables. Hypertense show a higher rate of suicidal thinking than normal people. Accordingly, it is necessary not only to pay attention to establishing plans to provide Hypertense and Diabetic patients with medical treatments, but to have more concern about their mental health so that they may be provided with a political support future.