• Proceedings of the Materials Research Society of Korea Conference
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• 1998.08a
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• pp.101.4-101
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• 1998

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2019.10a
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• pp.58-58
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• 2019

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.6
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• pp.614-620
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• 2014

Kainic acid (KA) is a excitatory agonist causing epileptic seizure and excitotoxicity in the hippocampus. Gastrodia Elata (GE) is known to have anti-convulsant and anti-oxidant effects. This study was investigated a possible role of GE in suppressing epileptic seizure using KA-induced epilepsy mouse model. Eight-week-old male C57BL/6 mice were administrated GE (50 or 500 mg/kg) once a day for 5 days, and then injected KA (30 mg/kg) intraperitoneally. Behavioral changes in mice by KA were evaluated for 90 minutes immediately after the KA administration. Six hours after the KA administration, their brains were harvested and the expressions of glutamate decarboxylase 67 (GAD-67) and K+-Cl- cotransporter 2 (KCC2) in the hippocampus of the mice were measured by immunohistochemistry.GE delayed the onset of epileptic seizure after KA administration, suppressed the severity of the seizure and decreased the number of severe seizures dose dependently. Moreover, GAD-67 and KCC2 expressions in the cornu ammonis (CA) 1 and CA3 of 500 mg/kg GE administrated mice were significantly increased compared to those in KA-treated mice.GAD-67 and KCC2 play an important role in regulating GABAergic system. Our results suggest that GE has anti-convulsant effect against KA-induced epileptic seizure through enhancing GABAergic system.

• Food Science and Preservation
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• v.12 no.6
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• pp.565-571
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• 2005

This study was to develope health promoting and better quality of Kochujang. Three kinds of medicinal plants, Angelica acutiloba (AA), Akebia quinate decaisne (AQ), Caragana chamlagu (CC) were extracted with water. Hanbang Kochujang was prepared by adding water extracts of medicinal hem to the ingredients of Kochujang. Quality characteristics of Hanbang Kochujang were evaluated by its water content, color and sensory evaluation during storage at $5^{\circ}C$: and $20^{\circ}C$ for 90 days. Moisture contents of Hanbang Kochujang before storage were $33\~38\%$ and increased to $48\~51\%$ at the end of storage. Color values(L, a and b) of Hanbang Kochujang were decreased as the progress of storage period at $5^{\circ}C$ and $20^{\circ}C$. Redness (a) values of Hannbang Kochujang with Akebia quinate decaisne (KAQ) and Caragana chamlagu (KCC) were lower than that of control Kochujang (KC) during storage at $20^{\circ}C$(p<0.05). Yellowness(b) values of Hannbang Kochujang with Caragana chamlagu (KCC) was lower than that of control Kochujang (KC) during storage at $5^{\circ}C$(p<0.05). From sensory evaluation, preference was higher in Hanbang Kochujang (KAA, KAQ and KCC) stored at $20^{\circ}C$ than that stored at $5^{\circ}C$ during 60 and 90 days of storage. Sensory evaluation scores of color, sweet taste and overall preference were the highest in Hanbang Kochujang added Caragana chamlagu (KCC) during storage at $5^{\circ}C$ and $20^{\circ}C$ for 90 days (p<0.05).

• The Science & Technology
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• v.32 no.1 s.356
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• pp.74-77
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• 1999

북한의 정보화는 어디까지 와 있는가. 한마디로 북한의 정보화는 경제사정 악화와 심각한 식량난으로 어려움을 겪고 있다. 하드웨어부문은 자본부족과 외자유치 부진으로 위축되어 있으나 소프트웨어부문은 계속 발전을 보이고 있다. KCC(조선콤퓨터쎈터), PIC, 은별 콤퓨터기술연구소의 제품과 실태를 살펴본다.

• Spatial Information Research
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• v.19 no.4
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• pp.33-43
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• 2011

Countries all over the world have been operating various certification systems to protect their consumers, and these systems have become trade barriers between countries. Also, KS and KCC were not designed to reflect characteristics of Geo-Spatial Information Device. The purpose of this study was to derive the plan of Quality Certification System for Geo-Spatial Information Device through the analyses of the existing Quality Certification System. The results of this study were as follows. Firstly, we defined the concept of Quality Certification System for Geo-Spatial Information Device. Secondly, we set the boundary, factors and process of Quality Certification System for Geo-Spatial Information Device through classifying it in detail. Lastly, we suggested about fundamental concept of Quality Certification System for Geo-Spatial Information Device a the analyses of the existing Quality Certification System.

• Biomolecules & Therapeutics
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• v.17 no.4
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• pp.379-387
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• 2009

We have previously reported that N-ethylmaleimide (NEM) induces apoptosis through activation of $K^+$, $Cl^-$-cotransport (KCC) in HepG2 human hepatoblastoma cells. In this study we investigated the possible role of phospholipase $A_2$ ($PLA_2$)-arachidonic acid (AA) signals in the mechanism of the NEM-induced apoptosis. In these experiments we used arachidonyl trifluoromethylketone ($AACOCF_3$), bromoenol lactone (BEL) and p-bromophenacyl bromide (BPB) as inhibitors of the calcium-dependent cytosolic $PLA_2$ ($cPLA_2$), the calcium-independent $PLA_2$ ($iPLA_2$) and the secretory $PLA_2$ ($sPLA_2$), respectively. BEL significantly inhibited the NEM-induced apoptosis, whereas $AACOCF_3$ and BPB did not. NEM increased AA liberation in a dose-dependent manner, which was markedly prevented only by BEL. In addition AA by itself induced $K^+$ efflux, a hallmark of KCC activation, which was comparable to that of NEM. The NEM-induced apoptosis was not significantly altered by treatment with indomethacin (Indo) and nordihydroguaiaretic acid (NDGA), selective inhibitors of cyclooxygenase (COX) and lipoxygenase (LOX), respectively. Treatment with AA or 5,8,11,14-eicosatetraynoic acid (ETYA), a non-metabolizable analogue of AA, significantly induced apoptosis. Collectively, these results suggest that AA liberated through activation of $iPLA_2$ may mediate the NEMinduced apoptosis in HepG2 cells.

• ETRI Journal
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• v.30 no.6
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• pp.871-873
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• 2008

In this letter, we investigate the spectral efficiency of IEEE 802.22 wireless regional area network (WRAN) spectrum overlay when it is used in TV white space. Since 2004, when the FCC published the notice of proposed rule making 04-186 to make use of unused TV spectrum, the IEEE 802.22 working group has been standardizing specifications for WRAN operations. There have been a few papers investigating the spectral efficiency of this, but their analyses were limited to the cases for various guard distances between WRAN base stations. Since WRAN base station (BS) power for WRAN service may differ from country to country, it is important to analyze the spectral efficiency for various WRAN BS powers. In this letter, we analyze the spectral efficiency of WRAN spectrum overlay as a function of the power of WRAN BSs. The simulation results show that spectral efficiency decreases as the power of WRAN BSs and guard distances increase.

• Journal of Korea Society of Digital Industry and Information Management
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• v.16 no.3
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• pp.13-23
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• 2020

Currently, online means of replacing resident registration numbers(RRN) include I-Pin, mobile phone, credit card, MyPin, and general-purpose certificate. In order to issue alternative means based on the RRN, it must be designated through the designation review by the Korea Communications Commission(KCC) through a designation review by personal proofing agency and be subject to annual management. However, the criteria for designation and follow-up of the designation of the personal proofing agency carried out by KCC have been used in 2010 without revision, and there are problems that do not conform to the evaluation standards of various alternative means. Therefore, in this paper, we propose a method for improving the designation criteria and management system of the personal proofing service agency. The proposed method analyzes the characteristics of the alternative identification-based personal proofing service and proposes a follow-up management standard that can appropriately evaluate the analyzed characteristics and improves the designation criteria according to the emergence of new alternatives. Through the proposed method, it can be seen that it is possible to strengthen the safety of the personal proofing service based on the alternative means of RRN provided online and face-to-face and to protect the user's personal information.

• Journal of Microbiology and Biotechnology
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• v.5 no.1
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• pp.18-21
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• 1995

Endoglucanase gene of Pseudomonas sp. LBC505 was previously cloned in pUCl9 to yield plasmid pLC1. overproduction of endoglucanase was attempted by following ways. First, the endoglucanase gene of Pseudomonas sp. LBC505 cloned in pUCl9(pLC1) was tandemly inserted, step by step, into a expression vector pKK223-3 in a directly repeated form to enhance productivity of endoglucanase. Escherichia coli containing pKCC30 among the resulting plasm ids showed the higher yield of the endoglucanase. Ecoli harboring pKCC30 which had three inserted endoglucanase genes expressed about 12.3 times as much CMCase activity as Ecoli harboring pLCl. Second, the endoglucanase gene was subcloned into Bacillus subtilis expression vector pgnt41 for both overproduction and extracellular secretion of the endoglucanase. A resulting plasmid pgntc15 in Bacillus subtilis expressed 4.3-fold higher levels of CMCase activity than that of E.coli harboring pLCl and the endoglucanase produced was entirely secreted into the culture medium.