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검색결과 6,998건 처리시간 0.036초

Protein-Protein Interaction between Poly(A) Polymerase and Cyclophilin A in Chemotactic Cells

  • Choi, Hyun-Sook;Kim, Hana;Lee, Changgook;Kim, Youngmi;Lee, Younghoon
    • Bulletin of the Korean Chemical Society
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    • 제35권1호
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    • pp.83-86
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    • 2014
  • Poly(A) polymerase (PAP) play an essential role for maturation of mRNA by adding the adenylate residues at the 3' end. PAP functions are regulated through protein-protein interaction at its C-terminal region. In this study, cyclophilin A (CypA), a member of the peptidyl-prolyl cis-trans isomerase family, was identified as a partner protein interacting with the C-terminal region PAP. The interaction between PAP and CypA was inhibited by the immunosuppressive drug cyclosporine A. Deletion analysis revealed that the N-terminal 56 residues of CypA are sufficient for the interaction with PAP. Interestingly, we observed that PAP and CypA colocalize in the nucleus during SDF-1-induced chemotaxis, implying that CypA could be involved in the regulation of polyadenylation by PAP in the chemotactic cells.

Statistical Analysis of Fluorescence Correlation Spectroscopy of Ultra Low Concentration Molecules with a Confocal Microscope

  • Lee, Soon-Hyouk;Lim, Gyu-Chang;Kim, Soo-Yong;Kim, Eun-Kyung;Kim, Hak-Sung;Kim, Sok-Won
    • Journal of the Optical Society of Korea
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    • 제12권3호
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    • pp.170-173
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    • 2008
  • In this study, we simulated a statistical model of FCS(fluorescence correlation spectroscopy) based on a Poisson process to understand and explain observations of the experiment performed on molecules of ultra-low concentration by the home-built laser-scanning confocal microscope. The statistical model confirmed that the relative mean square amplitude of fluctuations is shown to be inversely proportional to the average number of molecules, even in the ultra-low concentration, if some conditions are satisfied. Signal-to-noise ratio and the variability of dwelling time under the confocal volume were found to be effective conditions for the experiment.

Low Cycle Fatigue Behaviors of Type 316 Stainless Steel in $310^{\circ}C$ Water Environment

  • Kim, Byoung-Koo;Cho, Hyun-Chul;Kim, In-Sup;Jang, Chang-Heui;Jung, Dae-Yul;Byeon, Seong-Cheol
    • 한국원자력학회:학술대회논문집
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    • 한국원자력학회 2005년도 춘계학술발표회
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    • pp.467-468
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    • 2005
  • Low cycle fatigue test results of Type 316 stainless steel in $310^{\circ}C$ water environment can be summarized as follows. 1. Cyclic stress response of Type 316 stainless steel shows negative strain rate sensitivity, primary hardening and secondary hardening. 2. Fatigue life in $310^{\circ}C$ water environment was shorter than fatigue life in room temperature air environment. This was because of water environment and temperature effects.

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DESIGN AND IMPLEMENTATION OF ON-BOARD COMPUTERS FOR STSAT-2

  • Ryu Changwan;Choi Myungjin;Oh Daesoo;Kang Kyungin;Nam Myeong-Ryong;Keum Junghoon
    • 한국우주과학회:학술대회논문집(한국우주과학회보)
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    • 한국우주과학회 2004년도 한국우주과학회보 제13권2호
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    • pp.293-295
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    • 2004
  • The Engineering Model of on-board computer was developed and tested completely with other sub-systems for STSAT-2. We designed the on-board computer of STSAT-2 which has some improved features compared with that of STSAT-l. A remarkable change is that the on-board computer has a structure of centeralized network communication without a Network Controller of the STSAT-l. That is, the on-board computer directly manages a satellite network. In addition, as many logics are implemented by Field Programmable Gate Array, so we can reduce the weight and size of on-board computer. Also, the developed on-board computer has more improved tolerance against Single Event Upsets and faults than that of the STSAT-l.

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이동평균 코시 잡음에서의 약한 다진 신호 검파 (Detection of Weak M-ary Signals in Moving-Average of Cauchy Noise)

  • 오종호;이주미;권형문;강현구;송익호
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2006년도 하계종합학술대회
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    • pp.171-172
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    • 2006
  • In first-order moving-average Cauchy noise, the maximum likelihood (ML) and suboptimum ML (S-ML) detectors are analyzed in terms of the bit-error-rate in impulsive environment. Despite reduced complexity and simpler structure, the S-ML detector exhibits practically the same performance as the ML detector.

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High performance Organic-Inorganic Hybrid Materials for Application in OLED Barrier Coating

  • Jung, Kyung-Ho;Yun, Chang-Hun;Bae, Jun-Young;Yoo, Seung-Hyup;Bae, Byeong-Soo
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2009년도 9th International Meeting on Information Display
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    • pp.806-809
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    • 2009
  • Epoxy functionalized organic-inorganic hybrid materials (hybrimers) were synthesized by sol-gel reaction for application in OLED barrier coating. By using the calcium degradation method, the oxygen transition rate (OTR) and water vapor transition rate (WVTR) measured so far is $10^{-2}cc/m^2$-day for oxygen and $10^{-1}g/m^2$-day for water molecules with single hybrimer coating film, respectively. Encapsulated OLED devices have life time of 14hrs of a single hybrimer barrier coating and 29hrs of hybrimer/inorganic double barrier coatings at $25^{\circ}C$ and 60% relative humidity.

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Fabrication of Flexible Photoluminescent Display for Improving Reliability

  • Choi, Kyung-Cheol;Kim, Seung-Hun;Jang, Cheol;Kim, Kuk-Joo;Ahn, Sung-Il
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2009년도 9th International Meeting on Information Display
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    • pp.337-338
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    • 2009
  • A flexible photoluminescent display device was proposed and fabrication technology with a low process temperature was investigated in order to improve its reliability. The proposed flexible photoluminescent display showed good characteristics in reliability and flexibility. The lifetime of the proposed flexible photoluminescent displays with organics components is estimated to be approximately more than 10,000 hours.

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금속 차폐 공간 내 원거리 무선전력전송 기술의 적용 검토 (A Study on the Application of Wireless Power Transfer Technologies in Metal Shielding Spaces)

  • 정석용;최보환;유승진;구범우;임춘택
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 2013년도 전력전자학술대회 논문집
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    • pp.335-336
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    • 2013
  • 본 논문에서 금속 차폐 공간 내 원거리 무선 전력전송 기술의 적용방법을 제시한다. 논문에서 고려된 금속 차폐 공간은 무선 전력전송 송수신코일의 후면 및 천장, 바닥에 위치하는 철, 알루미늄, 페라이트 3종류의 금속판들로 구성된다. 본 논문에서는 유한요소해석 시뮬레이션(Ansoft Maxwell)을 통해 송수신코일 간 자기결합 측면에서 철, 페라이트 금속판 보다 우수한 알루미늄 금속판의 특성을 검토하였다.

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미세조류 Nannochloris oculata의 성장과 지질 생산에 미치는 질소 농도와 광량의 영향 (Production of Biomass and Lipid Using Microalga Nannochloris oculata Under Different Conditions of Nitrogen and Irradiance)

  • 박상진;최윤이;김철웅;박원근;양지원
    • KSBB Journal
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    • 제25권6호
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    • pp.553-558
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    • 2010
  • Increasing demands on fossil fuel have led to the unprecedented attraction to microalgal biofuel as an alternative energy. In this study, we investigated growth and lipid productions of microalga Nannochloris oculata under various carbon dioxide or nitrogen source concentrations and irradiance conditions. Biomass production of N. oculata was highest under 2% $CO_2$ with 0.3 flow rate (vvm). In addition, biomass productivities were proportional to the concentration of nitrogen source, whereas lipid biosynthesis was suppressed under higher nitrogen concentration (up to 50 mg/L). High irradiation ($160{\sim}180\;{\mu}mol/m^2{\cdot}s$) enhanced growth rate and lipid production of N. oculata.